| 2002-03-31 | vs CLE | 1 | L 0-6 | 0-1 | 1 | 42,697 | Jarrod Washburn | Bartolo Colon | Bartolo Colon | Jarrod Washburn | | 0 | 6 | -6 |
| 2002-04-02 | vs CLE | 2 | W 7-5 | 1-1 | 2 | 20,055 | Kevin Appier | CC Sabathia | Ben Weber | David Riske | Troy Percival | 7 | 11 | -4 |
| 2002-04-03 | vs CLE | 3 | L 5-6 | 1-2 | 3 | 18,194 | Aaron Sele | Ryan Drese | Ryan Drese | Aaron Sele | Bob Wickman | 12 | 17 | -5 |
| 2002-04-05 | @ TEX | 4 | W 3-1 | 2-2 | 3 | 49,617 | Scott Schoeneweis | Ismael Valdez | Scott Schoeneweis | Ismael Valdez | Al Levine | 15 | 18 | -3 |
| 2002-04-06 | @ TEX | 5 | W 6-3 | 3-2 | 2 | 35,006 | Ramon Ortiz | Hideki Irabu | Ramon Ortiz | Hideki Irabu | Al Levine | 21 | 21 | 0 |
| 2002-04-08 | vs SEA | 6 | L 4-5 | 3-3 | 3 | 16,908 | Jarrod Washburn | Paul Abbott | Shigetoshi Hasegawa | Ben Weber | Kazuhiro Sasaki | 25 | 26 | -1 |
| 2002-04-09 | vs SEA | 7 | L 1-5 | 3-4 | 3 | 17,210 | Kevin Appier | John Halama | John Halama | Kevin Appier | | 26 | 31 | -5 |
| 2002-04-10 | vs SEA | 8 | L 1-8 | 3-5 | 3 | 17,784 | Aaron Sele | James Baldwin | James Baldwin | Aaron Sele | | 27 | 39 | -12 |
| 2002-04-11 | vs SEA | 9 | L 4-8 | 3-6 | 3 | 18,806 | Scott Schoeneweis | Freddy Garcia | Freddy Garcia | Scott Schoeneweis | | 31 | 47 | -16 |
| 2002-04-12 | vs OAK | 10 | L 1-5 | 3-7 | 3 | 31,815 | Ramon Ortiz | Tim Hudson | Tim Hudson | Ramon Ortiz | | 32 | 52 | -20 |
| 2002-04-13 | vs OAK | 11 | L 2-7 | 3-8 | 3 | 33,554 | Jarrod Washburn | Erik Hiljus | Erik Hiljus | Jarrod Washburn | | 34 | 59 | -25 |
| 2002-04-14 | vs OAK | 12 | W 4-1 | 4-8 | 3 | 32,881 | Kevin Appier | Barry Zito | Kevin Appier | Barry Zito | Al Levine | 38 | 60 | -22 |
| 2002-04-16 | vs TEX | 13 | W 6-5 | 5-8 | 3 | 15,385 | Aaron Sele | Doug Davis | Al Levine | John Rocker | | 44 | 65 | -21 |
| 2002-04-17 | vs TEX | 14 | L 1-4 | 5-9 | 3 | 15,632 | Scott Schoeneweis | Ismael Valdez | Ismael Valdez | Scott Schoeneweis | Hideki Irabu | 45 | 69 | -24 |
| 2002-04-18 | @ OAK | 15 | L 2-4 | 5-10 | 3 | 9,145 | Ramon Ortiz | Erik Hiljus | Erik Hiljus | Ramon Ortiz | Billy Koch | 47 | 73 | -26 |
| 2002-04-19 | @ OAK | 16 | W 9-7 | 6-10 | 3 | 12,468 | Jarrod Washburn | Mike Fyhrie | Jarrod Washburn | Mike Fyhrie | Troy Percival | 56 | 80 | -24 |
| 2002-04-20 | @ OAK | 17 | L 7-8 | 6-11 | 3 | 20,253 | Kevin Appier | Barry Zito | Chad Bradford | Al Levine | Billy Koch | 63 | 88 | -25 |
| 2002-04-21 | @ OAK | 18 | L 5-6 | 6-12 | 3 | 20,088 | Aaron Sele | Cory Lidle | Mike Venafro | Troy Percival | | 68 | 94 | -26 |
| 2002-04-22 | @ SEA | 19 | L 5-16 | 6-13 | 3 | 33,119 | Scott Schoeneweis | Jamie Moyer | Jamie Moyer | Scott Schoeneweis | | 73 | 110 | -37 |
| 2002-04-23 | @ SEA | 20 | L 0-1 | 6-14 | 3 | 32,127 | Ramon Ortiz | Ryan Franklin | Ryan Franklin | Ramon Ortiz | Kazuhiro Sasaki | 73 | 111 | -38 |
| 2002-04-24 | @ SEA | 21 | W 10-6 | 7-14 | 3 | 37,212 | Jarrod Washburn | Paul Abbott | Jarrod Washburn | Paul Abbott | | 83 | 117 | -34 |
| 2002-04-26 | vs TOR | 22 | W 4-0 | 8-14 | 3 | 25,296 | Kevin Appier | Michael Smith | Kevin Appier | Michael Smith | Troy Percival | 87 | 117 | -30 |
| 2002-04-27 | vs TOR | 23 | W 11-4 | 9-14 | 3 | 29,112 | Aaron Sele | Justin Miller | Aaron Sele | Pedro Borbon | | 98 | 121 | -23 |
| 2002-04-28 | vs TOR | 24 | W 8-5 | 10-14 | 3 | 25,073 | Scott Schoeneweis | Brandon Lyon | Mark Lukasiewicz | Pedro Borbon | | 106 | 126 | -20 |
| 2002-04-30 | @ CLE | 25 | W 21-2 | 11-14 | 3 | 24,286 | Ramon Ortiz | CC Sabathia | Ramon Ortiz | CC Sabathia | | 127 | 128 | -1 |
| 2002-05-01 | @ CLE | 26 | W 7-2 | 12-14 | 3 | 23,536 | Jarrod Washburn | Ryan Drese | Jarrod Washburn | Ryan Drese | | 134 | 130 | 4 |
| 2002-05-02 | @ CLE | 27 | W 8-0 | 13-14 | 3 | 26,068 | Kevin Appier | Chuck Finley | Kevin Appier | Chuck Finley | | 142 | 130 | 12 |
| 2002-05-03 | @ TOR | 28 | W 6-4 | 14-14 | 3 | 13,183 | Aaron Sele | Brandon Lyon | Aaron Sele | Brandon Lyon | Troy Percival | 148 | 134 | 14 |
| 2002-05-04 | @ TOR | 29 | L 1-4 | 14-15 | 3 | 20,558 | Scott Schoeneweis | Justin Miller | Justin Miller | Scott Schoeneweis | Kelvim Escobar | 149 | 138 | 11 |
| 2002-05-05 | @ TOR | 30 | W 8-2 | 15-15 | 3 | 24,046 | Ramon Ortiz | Luke Prokopec | Ramon Ortiz | Luke Prokopec | | 157 | 140 | 17 |
| 2002-05-07 | vs DET | 31 | L 0-3 | 15-16 | 3 | 15,315 | Jarrod Washburn | Seth Greisinger | Seth Greisinger | Ben Weber | Juan Acevedo | 157 | 143 | 14 |
| 2002-05-08 | vs DET | 32 | W 3-2 | 16-16 | 3 | 14,722 | Kevin Appier | Nate Cornejo | Troy Percival | Fernando Rodney | | 160 | 145 | 15 |
| 2002-05-09 | vs DET | 33 | W 7-6 | 17-16 | 2 | 15,003 | Aaron Sele | Mark Redman | Aaron Sele | Mark Redman | Troy Percival | 167 | 151 | 16 |
| 2002-05-10 | vs CHA | 34 | W 19-0 | 18-16 | 2 | 36,715 | Scott Schoeneweis | Dan Wright | Scott Schoeneweis | Dan Wright | | 186 | 151 | 35 |
| 2002-05-11 | vs CHA | 35 | W 6-3 | 19-16 | 2 | 40,535 | Ramon Ortiz | Jon Garland | Ramon Ortiz | Jon Garland | Troy Percival | 192 | 154 | 38 |
| 2002-05-12 | vs CHA | 36 | W 5-4 | 20-16 | 2 | 19,251 | Jarrod Washburn | Gary Glover | Troy Percival | Keith Foulke | | 197 | 158 | 39 |
| 2002-05-14 | @ DET | 37 | W 9-2 | 21-16 | 2 | 12,745 | Kevin Appier | Nate Cornejo | Kevin Appier | Nate Cornejo | | 206 | 160 | 46 |
| 2002-05-15 | @ DET | 38 | W 10-1 | 22-16 | 2 | 12,314 | Aaron Sele | Mark Redman | Aaron Sele | Mark Redman | | 216 | 161 | 55 |
| 2002-05-17 | @ CHA | 39 | W 8-4 | 23-16 | 2 | 12,736 | Scott Schoeneweis | Jon Garland | Scott Schoeneweis | Jon Garland | Al Levine | 224 | 165 | 59 |
| 2002-05-18 | @ CHA | 40 | L 4-10 | 23-17 | 2 | 21,122 | Ramon Ortiz | Gary Glover | Gary Glover | Ramon Ortiz | | 228 | 175 | 53 |
| 2002-05-19 | @ CHA | 41 | W 6-1 | 24-17 | 2 | 19,869 | Jarrod Washburn | Mark Buehrle | Jarrod Washburn | Mark Buehrle | | 234 | 176 | 58 |
| 2002-05-20 | vs KCA | 42 | W 6-3 | 25-17 | 2 | 14,035 | Kevin Appier | Blake Stein | Kevin Appier | Blake Stein | Troy Percival | 240 | 179 | 61 |
| 2002-05-21 | vs KCA | 43 | W 5-1 | 26-17 | 2 | 15,593 | Aaron Sele | Miguel Asencio | Dennis Cook | Dan Reichert | | 245 | 180 | 65 |
| 2002-05-22 | vs KCA | 44 | W 7-6 | 27-17 | 2 | 16,163 | Scott Schoeneweis | Paul Byrd | Ben Weber | Darrell May | Troy Percival | 252 | 186 | 66 |
| 2002-05-24 | vs MIN | 45 | L 1-5 | 27-18 | 2 | 27,494 | Ramon Ortiz | Rick Reed | Rick Reed | Ramon Ortiz | | 253 | 191 | 62 |
| 2002-05-25 | vs MIN | 46 | W 4-3 | 28-18 | 2 | 31,820 | Jarrod Washburn | Matt Kinney | Al Levine | Jack Cressend | | 257 | 194 | 63 |
| 2002-05-26 | vs MIN | 47 | L 2-5 | 28-19 | 2 | 22,854 | Kevin Appier | Eric Milton | Eric Milton | Kevin Appier | Eddie Guardado | 259 | 199 | 60 |
| 2002-05-28 | @ KCA | 48 | L 4-7 | 28-20 | 2 | 11,773 | Aaron Sele | Paul Byrd | Paul Byrd | Aaron Sele | Roberto Hernandez | 263 | 206 | 57 |
| 2002-05-29 | @ KCA | 49 | W 12-2 | 29-20 | 2 | 13,662 | Ramon Ortiz | Jeremy Affeldt | Ramon Ortiz | Jeremy Affeldt | | 275 | 208 | 67 |
| 2002-05-30 | @ MIN | 50 | L 6-7 | 29-21 | 2 | 14,521 | Scott Schoeneweis | Brad Radke | Eddie Guardado | Lou Pote | | 281 | 215 | 66 |
| 2002-05-31 | @ MIN | 51 | W 11-3 | 30-21 | 2 | 17,101 | Jarrod Washburn | Eric Milton | Jarrod Washburn | Eric Milton | | 292 | 218 | 74 |
| 2002-06-01 | @ MIN | 52 | L 2-4 | 30-22 | 2 | 17,480 | Kevin Appier | Kyle Lohse | Kyle Lohse | Kevin Appier | Eddie Guardado | 294 | 222 | 72 |
| 2002-06-02 | @ MIN | 53 | W 5-4 | 31-22 | 2 | 18,657 | Aaron Sele | Matt Kinney | Aaron Sele | Matt Kinney | Troy Percival | 299 | 226 | 73 |
| 2002-06-03 | vs TEX | 54 | W 5-2 | 32-22 | 2 | 15,619 | Ramon Ortiz | Rob Bell | Ramon Ortiz | Rob Bell | Troy Percival | 304 | 228 | 76 |
| 2002-06-04 | vs TEX | 55 | W 3-0 | 33-22 | 2 | 16,810 | Scott Schoeneweis | Dave Burba | Scott Schoeneweis | Dave Burba | Troy Percival | 307 | 228 | 79 |
| 2002-06-05 | vs TEX | 56 | W 7-5 | 34-22 | 2 | 15,301 | Jarrod Washburn | Ismael Valdez | Al Levine | Hideki Irabu | | 314 | 233 | 81 |
| 2002-06-06 | vs TEX | 57 | L 8-9 | 34-23 | 2 | 17,948 | Kevin Appier | Kenny Rogers | Kenny Rogers | Kevin Appier | Anthony Telford | 322 | 242 | 80 |
| 2002-06-07 | vs CIN | 58 | W 4-3 | 35-23 | 2 | 35,341 | Aaron Sele | Chris Reitsma | Aaron Sele | Chris Reitsma | Troy Percival | 326 | 245 | 81 |
| 2002-06-08 | vs CIN | 59 | L 3-4 | 35-24 | 2 | 29,881 | Ramon Ortiz | Elmer Dessens | Gabe White | Dennis Cook | Danny Graves | 329 | 249 | 80 |
| 2002-06-09 | vs CIN | 60 | W 7-4 | 36-24 | 2 | 35,501 | Scott Schoeneweis | Joey Hamilton | Scott Schoeneweis | Joey Hamilton | Troy Percival | 336 | 253 | 83 |
| 2002-06-10 | vs PIT | 61 | W 4-3 | 37-24 | 2 | 16,861 | Jarrod Washburn | Jimmy Anderson | Jarrod Washburn | Jimmy Anderson | Troy Percival | 340 | 256 | 84 |
| 2002-06-11 | vs PIT | 62 | L 3-7 | 37-25 | 2 | 17,755 | Kevin Appier | Josh Fogg | Josh Fogg | Kevin Appier | | 343 | 263 | 80 |
| 2002-06-12 | vs PIT | 63 | W 8-5 | 38-25 | 2 | 17,096 | Aaron Sele | Joe Beimel | Ben Weber | Brian Boehringer | Troy Percival | 351 | 268 | 83 |
| 2002-06-14 | @ LAN | 64 | W 8-4 | 39-25 | 2 | 51,722 | Ramon Ortiz | Kazuhisa Ishii | Ramon Ortiz | Kazuhisa Ishii | | 359 | 272 | 87 |
| 2002-06-15 | @ LAN | 65 | L 5-10 | 39-26 | 2 | 52,165 | Scott Schoeneweis | Odalis Perez | Odalis Perez | Scott Schoeneweis | | 364 | 282 | 82 |
| 2002-06-16 | @ LAN | 66 | L 4-5 | 39-27 | 2 | 52,183 | Jarrod Washburn | Hideo Nomo | Giovanni Carrara | Al Levine | Eric Gagne | 368 | 287 | 81 |
| 2002-06-18 | @ SLN | 67 | L 2-7 | 39-28 | 2 | 39,386 | Kevin Appier | Darryl Kile | Darryl Kile | Kevin Appier | | 370 | 294 | 76 |
| 2002-06-19 | @ SLN | 68 | L 2-6 | 39-29 | 2 | 35,432 | Aaron Sele | Matt Morris | Matt Morris | Aaron Sele | | 372 | 300 | 72 |
| 2002-06-20 | @ SLN | 69 | W 3-2 | 40-29 | 2 | 36,385 | Scott Schoeneweis | Bud Smith | Scott Schoeneweis | Bud Smith | Troy Percival | 375 | 302 | 73 |
| 2002-06-21 | @ MIL | 70 | W 11-4 | 41-29 | 2 | 20,289 | Ramon Ortiz | Ruben Quevedo | Ramon Ortiz | Ruben Quevedo | | 386 | 306 | 80 |
| 2002-06-22 | @ MIL | 71 | W 8-2 | 42-29 | 2 | 28,765 | Jarrod Washburn | Jose Cabrera | Jarrod Washburn | Jose Cabrera | | 394 | 308 | 86 |
| 2002-06-23 | @ MIL | 72 | W 5-2 | 43-29 | 2 | 23,751 | Kevin Appier | Ben Sheets | Kevin Appier | Ben Sheets | Troy Percival | 399 | 310 | 89 |
| 2002-06-24 | @ TEX | 73 | L 5-8 | 43-31 | 3 | 0 | Aaron Sele | Joaquin Benoit | Joaquin Benoit | Aaron Sele | | 404 | 318 | 86 |
| 2002-06-24 | @ TEX | 74 | L 2-3 | 43-31 | 3 | 23,103 | John Lackey | Dave Burba | Dave Burba | John Lackey | Hideki Irabu | 406 | 321 | 85 |
| 2002-06-25 | @ TEX | 75 | L 5-11 | 43-32 | 3 | 20,089 | Scott Schoeneweis | Ismael Valdez | Ismael Valdez | Scott Schoeneweis | | 411 | 332 | 79 |
| 2002-06-26 | @ TEX | 76 | W 7-6 | 44-32 | 2 | 29,726 | Ramon Ortiz | Aaron Myette | Ben Weber | Hideki Irabu | Troy Percival | 418 | 338 | 80 |
| 2002-06-27 | @ TEX | 77 | W 6-3 | 45-32 | 2 | 22,077 | Jarrod Washburn | Rob Bell | Jarrod Washburn | Rob Bell | Troy Percival | 424 | 341 | 83 |
| 2002-06-28 | vs LAN | 78 | L 5-7 | 45-33 | 2 | 43,690 | Kevin Appier | Andy Ashby | Giovanni Carrara | Scot Shields | Eric Gagne | 429 | 348 | 81 |
| 2002-06-29 | vs LAN | 79 | W 7-0 | 46-33 | 2 | 43,502 | Aaron Sele | Kazuhisa Ishii | Aaron Sele | Kazuhisa Ishii | | 436 | 348 | 88 |
| 2002-06-30 | vs LAN | 80 | W 5-1 | 47-33 | 2 | 43,059 | John Lackey | Odalis Perez | John Lackey | Odalis Perez | Ben Weber | 441 | 349 | 92 |
| 2002-07-02 | vs BAL | 81 | L 0-3 | 47-34 | 2 | 18,521 | Ramon Ortiz | Rodrigo Lopez | Rodrigo Lopez | Ramon Ortiz | Jorge Julio | 441 | 352 | 89 |
| 2002-07-03 | vs BAL | 82 | W 1-0 | 48-34 | 2 | 17,477 | Jarrod Washburn | Scott Erickson | Jarrod Washburn | Scott Erickson | Troy Percival | 442 | 352 | 90 |
| 2002-07-04 | vs BAL | 83 | L 2-7 | 48-35 | 2 | 43,342 | Kevin Appier | Travis Driskill | Travis Driskill | Kevin Appier | | 444 | 359 | 85 |
| 2002-07-05 | vs TBA | 84 | W 6-5 | 49-35 | 2 | 23,648 | Aaron Sele | Joe Kennedy | Scot Shields | Esteban Yan | | 450 | 364 | 86 |
| 2002-07-06 | vs TBA | 85 | W 4-3 | 50-35 | 2 | 29,513 | John Lackey | Jorge Sosa | Scott Schoeneweis | Jesus Colome | Troy Percival | 454 | 367 | 87 |
| 2002-07-07 | vs TBA | 86 | W 2-1 | 51-35 | 2 | 26,446 | Ramon Ortiz | Tanyon Sturtze | Troy Percival | Travis Harper | | 456 | 368 | 88 |
| 2002-07-11 | @ KCA | 87 | W 1-0 | 52-35 | 2 | 13,031 | Jarrod Washburn | Darrell May | Jarrod Washburn | Darrell May | Troy Percival | 457 | 368 | 89 |
| 2002-07-12 | @ KCA | 88 | W 11-3 | 53-35 | 2 | 24,824 | Kevin Appier | Jeff Suppan | Kevin Appier | Jeff Suppan | | 468 | 371 | 97 |
| 2002-07-13 | @ KCA | 89 | L 0-4 | 53-36 | 2 | 19,504 | Aaron Sele | Paul Byrd | Paul Byrd | Aaron Sele | | 468 | 375 | 93 |
| 2002-07-14 | @ KCA | 90 | L 3-12 | 53-37 | 2 | 12,457 | Ramon Ortiz | Miguel Asencio | Miguel Asencio | Ramon Ortiz | | 471 | 387 | 84 |
| 2002-07-15 | @ MIN | 91 | L 8-10 | 53-38 | 2 | 19,189 | John Lackey | Johan Santana | LaTroy Hawkins | Scott Schoeneweis | Eddie Guardado | 479 | 397 | 82 |
| 2002-07-16 | @ MIN | 92 | W 4-2 | 54-38 | 2 | 26,258 | Jarrod Washburn | Eric Milton | Jarrod Washburn | Eric Milton | Ben Weber | 483 | 399 | 84 |
| 2002-07-17 | @ OAK | 93 | W 10-4 | 55-38 | 2 | 38,547 | Kevin Appier | Tim Hudson | Kevin Appier | Tim Hudson | | 493 | 403 | 90 |
| 2002-07-18 | @ OAK | 94 | L 0-2 | 55-39 | 2 | 15,733 | Aaron Sele | Barry Zito | Barry Zito | Aaron Sele | Billy Koch | 493 | 405 | 88 |
| 2002-07-19 | vs SEA | 95 | W 15-3 | 56-39 | 2 | 43,407 | Ramon Ortiz | Freddy Garcia | Ramon Ortiz | Freddy Garcia | | 508 | 408 | 100 |
| 2002-07-20 | vs SEA | 96 | W 7-6 | 57-39 | 2 | 43,109 | John Lackey | Ryan Franklin | Scot Shields | Arthur Rhodes | Ben Weber | 515 | 414 | 101 |
| 2002-07-21 | vs SEA | 97 | W 7-5 | 58-39 | 2 | 34,945 | Jarrod Washburn | Joel Pineiro | Jarrod Washburn | Jeff Nelson | Ben Weber | 522 | 419 | 103 |
| 2002-07-23 | vs OAK | 98 | L 1-2 | 58-40 | 2 | 25,370 | Kevin Appier | Barry Zito | Barry Zito | Kevin Appier | Billy Koch | 523 | 421 | 102 |
| 2002-07-24 | vs OAK | 99 | W 5-1 | 59-40 | 2 | 25,240 | Aaron Sele | Tim Hudson | Aaron Sele | Tim Hudson | | 528 | 422 | 106 |
| 2002-07-25 | vs OAK | 100 | W 5-4 | 60-40 | 2 | 31,653 | Ramon Ortiz | Cory Lidle | Scot Shields | Jim Mecir | Ben Weber | 533 | 426 | 107 |
| 2002-07-26 | @ SEA | 101 | W 8-0 | 61-40 | 1 | 45,559 | John Lackey | James Baldwin | John Lackey | James Baldwin | | 541 | 426 | 115 |
| 2002-07-27 | @ SEA | 102 | L 1-3 | 61-41 | 2 | 45,974 | Jarrod Washburn | Joel Pineiro | Joel Pineiro | Jarrod Washburn | Kazuhiro Sasaki | 542 | 429 | 113 |
| 2002-07-28 | @ SEA | 103 | W 1-0 | 62-41 | 1 | 45,634 | Kevin Appier | Jamie Moyer | Kevin Appier | Kazuhiro Sasaki | Troy Percival | 543 | 429 | 114 |
| 2002-07-29 | vs BOS | 104 | W 5-4 | 63-41 | 1 | 27,929 | Aaron Sele | Casey Fossum | Scott Schoeneweis | Alan Embree | Troy Percival | 548 | 433 | 115 |
| 2002-07-30 | vs BOS | 105 | L 0-6 | 63-42 | 2 | 32,812 | Ramon Ortiz | Pedro Martinez | Pedro Martinez | Ramon Ortiz | | 548 | 439 | 109 |
| 2002-07-31 | vs BOS | 106 | L 1-2 | 63-43 | 2 | 28,227 | John Lackey | Tim Wakefield | Tim Wakefield | John Lackey | Ugueth Urbina | 549 | 441 | 108 |
| 2002-08-01 | vs NYA | 107 | W 2-1 | 64-43 | 2 | 42,897 | Jarrod Washburn | Jeff Weaver | Jarrod Washburn | Jeff Weaver | Troy Percival | 551 | 442 | 109 |
| 2002-08-02 | vs NYA | 108 | L 0-4 | 64-44 | 2 | 43,668 | Kevin Appier | Andy Pettitte | Andy Pettitte | Kevin Appier | Ramiro Mendoza | 551 | 446 | 105 |
| 2002-08-03 | vs NYA | 109 | W 5-4 | 65-44 | 2 | 43,619 | Aaron Sele | Orlando Hernandez | Troy Percival | Ramiro Mendoza | | 556 | 450 | 106 |
| 2002-08-04 | vs NYA | 110 | L 5-7 | 65-45 | 2 | 43,455 | Ramon Ortiz | David Wells | Mike Stanton | Scot Shields | Ramiro Mendoza | 561 | 457 | 104 |
| 2002-08-05 | @ DET | 111 | W 6-3 | 66-45 | 2 | 18,546 | John Lackey | Brian Powell | John Lackey | Brian Powell | Troy Percival | 567 | 460 | 107 |
| 2002-08-06 | @ CHA | 112 | W 11-2 | 67-45 | 2 | 17,706 | Jarrod Washburn | Dan Wright | Jarrod Washburn | Dan Wright | Al Levine | 578 | 462 | 116 |
| 2002-08-07 | @ CHA | 113 | L 6-7 | 67-46 | 2 | 14,253 | Kevin Appier | Gary Glover | Antonio Osuna | Brendan Donnelly | | 584 | 469 | 115 |
| 2002-08-08 | @ CHA | 114 | L 2-3 | 67-47 | 2 | 18,165 | Aaron Sele | Jim Parque | Jim Parque | Aaron Sele | Damaso Marte | 586 | 472 | 114 |
| 2002-08-09 | @ TOR | 115 | L 4-5 | 67-48 | 2 | 18,728 | Ramon Ortiz | Pete Walker | Pete Walker | Ramon Ortiz | Kelvim Escobar | 590 | 477 | 113 |
| 2002-08-10 | @ TOR | 116 | W 11-4 | 68-48 | 2 | 25,118 | John Lackey | Steve Parris | John Lackey | Steve Parris | | 601 | 481 | 120 |
| 2002-08-11 | @ TOR | 117 | W 1-0 | 69-48 | 2 | 34,013 | Jarrod Washburn | Roy Halladay | Jarrod Washburn | Roy Halladay | Troy Percival | 602 | 481 | 121 |
| 2002-08-12 | vs DET | 118 | W 7-0 | 70-48 | 2 | 19,709 | Kevin Appier | Mark Redman | Kevin Appier | Mark Redman | | 609 | 481 | 128 |
| 2002-08-13 | vs DET | 119 | W 7-6 | 71-48 | 2 | 19,694 | Aaron Sele | Jose Lima | Al Levine | Adam Bernero | | 616 | 487 | 129 |
| 2002-08-14 | vs DET | 120 | W 5-4 | 72-48 | 2 | 23,391 | Ramon Ortiz | Mike Maroth | Ramon Ortiz | Mike Maroth | Troy Percival | 621 | 491 | 130 |
| 2002-08-16 | vs CLE | 121 | W 5-4 | 73-48 | 2 | 41,356 | John Lackey | Ryan Drese | John Lackey | Ryan Drese | Troy Percival | 626 | 495 | 131 |
| 2002-08-17 | vs CLE | 122 | L 4-9 | 73-49 | 2 | 39,866 | Jarrod Washburn | Jason Phillips | Carl Sadler | Jarrod Washburn | | 630 | 504 | 126 |
| 2002-08-18 | vs CLE | 123 | W 4-1 | 74-49 | 2 | 41,059 | Kevin Appier | CC Sabathia | Kevin Appier | CC Sabathia | Troy Percival | 634 | 505 | 129 |
| 2002-08-20 | @ NYA | 124 | L 5-7 | 74-50 | 1 | 41,619 | Aaron Sele | Andy Pettitte | Andy Pettitte | Aaron Sele | Mike Stanton | 639 | 512 | 127 |
| 2002-08-21 | @ NYA | 125 | W 5-1 | 75-50 | 1 | 46,423 | Ramon Ortiz | Orlando Hernandez | Ben Weber | Jeff Weaver | | 644 | 513 | 131 |
| 2002-08-22 | @ NYA | 126 | L 2-4 | 75-51 | 3 | 43,222 | John Lackey | David Wells | David Wells | John Lackey | Steve Karsay | 646 | 517 | 129 |
| 2002-08-23 | @ BOS | 127 | L 1-4 | 75-52 | 3 | 33,221 | Jarrod Washburn | Pedro Martinez | Pedro Martinez | Jarrod Washburn | Ugueth Urbina | 647 | 521 | 126 |
| 2002-08-24 | @ BOS | 128 | W 2-0 | 76-52 | 2 | 32,510 | Kevin Appier | Tim Wakefield | Kevin Appier | Tim Wakefield | Troy Percival | 649 | 521 | 128 |
| 2002-08-25 | @ BOS | 129 | W 8-3 | 77-52 | 2 | 32,059 | Mickey Callaway | Derek Lowe | Scott Schoeneweis | Derek Lowe | | 657 | 524 | 133 |
| 2002-08-26 | @ BOS | 130 | L 9-10 | 77-53 | 3 | 32,869 | Ramon Ortiz | John Burkett | Ugueth Urbina | Scot Shields | | 666 | 534 | 132 |
| 2002-08-27 | vs TBA | 131 | W 7-3 | 78-53 | 2 | 19,869 | John Lackey | Victor Zambrano | John Lackey | Victor Zambrano | Ben Weber | 673 | 537 | 136 |
| 2002-08-28 | vs TBA | 132 | L 5-8 | 78-54 | 2 | 17,740 | Jarrod Washburn | Jorge Sosa | Esteban Yan | Al Levine | | 678 | 545 | 133 |
| 2002-08-29 | vs TBA | 133 | W 6-1 | 79-54 | 2 | 18,820 | Kevin Appier | Tanyon Sturtze | Kevin Appier | Tanyon Sturtze | | 684 | 546 | 138 |
| 2002-08-30 | vs BAL | 134 | W 6-2 | 80-54 | 2 | 29,959 | Mickey Callaway | Jason Johnson | Mickey Callaway | Jason Johnson | Scott Schoeneweis | 690 | 548 | 142 |
| 2002-08-31 | vs BAL | 135 | W 9-0 | 81-54 | 2 | 38,563 | Ramon Ortiz | Scott Erickson | Ramon Ortiz | Scott Erickson | | 699 | 548 | 151 |
| 2002-09-01 | vs BAL | 136 | W 9-3 | 82-54 | 2 | 24,592 | John Lackey | Rodrigo Lopez | John Lackey | Rodrigo Lopez | Troy Percival | 708 | 551 | 157 |
| 2002-09-03 | @ TBA | 137 | W 10-2 | 83-54 | 2 | 10,146 | Jarrod Washburn | Jorge Sosa | Jarrod Washburn | Jorge Sosa | | 718 | 553 | 165 |
| 2002-09-04 | @ TBA | 138 | W 4-2 | 84-54 | 2 | 10,161 | Kevin Appier | Tanyon Sturtze | Kevin Appier | Tanyon Sturtze | Troy Percival | 722 | 555 | 167 |
| 2002-09-05 | @ TBA | 139 | W 10-1 | 85-54 | 2 | 10,135 | Ramon Ortiz | Joe Kennedy | Ramon Ortiz | Joe Kennedy | | 732 | 556 | 176 |
| 2002-09-06 | @ BAL | 140 | W 6-3 | 86-54 | 2 | 24,045 | John Lackey | Sean Douglass | John Lackey | Sean Douglass | Troy Percival | 738 | 559 | 179 |
| 2002-09-07 | @ BAL | 141 | W 4-2 | 87-54 | 2 | 30,714 | Mickey Callaway | Rodrigo Lopez | Ben Weber | Jorge Julio | Troy Percival | 742 | 561 | 181 |
| 2002-09-08 | @ BAL | 142 | W 6-2 | 88-54 | 2 | 27,665 | Jarrod Washburn | Pat Hentgen | Jarrod Washburn | Pat Hentgen | Ben Weber | 748 | 563 | 185 |
| 2002-09-09 | vs OAK | 143 | L 1-2 | 88-55 | 2 | 28,145 | Kevin Appier | Tim Hudson | Tim Hudson | Kevin Appier | Billy Koch | 749 | 565 | 184 |
| 2002-09-10 | vs OAK | 144 | W 5-2 | 89-55 | 2 | 35,323 | Ramon Ortiz | Ted Lilly | Ramon Ortiz | Ted Lilly | Troy Percival | 754 | 567 | 187 |
| 2002-09-11 | vs OAK | 145 | W 6-5 | 90-55 | 2 | 34,302 | John Lackey | Cory Lidle | Scot Shields | Jeff Tam | Troy Percival | 760 | 572 | 188 |
| 2002-09-12 | vs OAK | 146 | W 7-6 | 91-55 | 1 | 31,304 | Mickey Callaway | Mark Mulder | Brendan Donnelly | Billy Koch | | 767 | 578 | 189 |
| 2002-09-13 | vs TEX | 147 | W 3-2 | 92-55 | 1 | 35,345 | Jarrod Washburn | Joaquin Benoit | Jarrod Washburn | Joaquin Benoit | Troy Percival | 770 | 580 | 190 |
| 2002-09-14 | vs TEX | 148 | W 8-6 | 93-55 | 1 | 39,909 | Kevin Appier | Dennys Reyes | Scot Shields | Todd Van Poppel | Troy Percival | 778 | 586 | 192 |
| 2002-09-15 | vs TEX | 149 | W 13-4 | 94-55 | 1 | 33,445 | Ramon Ortiz | Kenny Rogers | Ramon Ortiz | Kenny Rogers | | 791 | 590 | 201 |
| 2002-09-16 | @ OAK | 150 | L 3-4 | 94-56 | 1 | 22,326 | John Lackey | Cory Lidle | Billy Koch | Al Levine | | 794 | 594 | 200 |
| 2002-09-17 | @ OAK | 151 | W 1-0 | 95-56 | 1 | 25,894 | Jarrod Washburn | Mark Mulder | Ben Weber | Billy Koch | Troy Percival | 795 | 594 | 201 |
| 2002-09-18 | @ OAK | 152 | L 4-7 | 95-57 | 1 | 50,730 | Mickey Callaway | Barry Zito | Barry Zito | Mickey Callaway | Billy Koch | 799 | 601 | 198 |
| 2002-09-19 | @ OAK | 153 | L 3-5 | 95-58 | 2 | 27,435 | Kevin Appier | Tim Hudson | Tim Hudson | Kevin Appier | Billy Koch | 802 | 606 | 196 |
| 2002-09-20 | @ SEA | 154 | W 8-1 | 96-58 | 2 | 45,663 | Ramon Ortiz | Joel Pineiro | Ramon Ortiz | Joel Pineiro | | 810 | 607 | 203 |
| 2002-09-21 | @ SEA | 155 | L 4-6 | 96-59 | 2 | 45,784 | John Lackey | Freddy Garcia | Freddy Garcia | John Lackey | Kazuhiro Sasaki | 814 | 613 | 201 |
| 2002-09-22 | @ SEA | 156 | L 2-3 | 96-60 | 2 | 45,693 | Jarrod Washburn | Ryan Franklin | Ryan Franklin | Jarrod Washburn | Jeff Nelson | 816 | 616 | 200 |
| 2002-09-24 | @ TEX | 157 | L 1-2 | 96-61 | 2 | 21,869 | Kevin Appier | Joaquin Benoit | Joaquin Benoit | Kevin Appier | Francisco Cordero | 817 | 618 | 199 |
| 2002-09-25 | @ TEX | 158 | L 3-4 | 96-62 | 2 | 20,976 | Ramon Ortiz | Kenny Rogers | Rudy Seanez | Scott Schoeneweis | Francisco Cordero | 820 | 622 | 198 |
| 2002-09-26 | @ TEX | 159 | W 10-5 | 97-62 | 2 | 21,774 | John Lackey | Colby Lewis | John Lackey | Colby Lewis | | 830 | 627 | 203 |
| 2002-09-27 | vs SEA | 160 | L 6-7 | 97-63 | 2 | 43,452 | Scot Shields | Freddy Garcia | John Halama | Lou Pote | | 836 | 634 | 202 |
| 2002-09-28 | vs SEA | 161 | W 8-4 | 98-63 | 2 | 43,202 | Mickey Callaway | Ryan Franklin | Mickey Callaway | Ryan Franklin | | 844 | 638 | 206 |
| 2002-09-29 | vs SEA | 162 | W 7-6 | 99-63 | 2 | 42,878 | Aaron Sele | Ismael Valdez | Mark Lukasiewicz | Ismael Valdez | Brendan Donnelly | 851 | 644 | 207 |