| Central | W | L | Pct | GB |
| St. Louis | 95 | 67 | .586 | -- |
| Cincinnati | 85 | 77 | .525 | 10.0 |
| Milwaukee | 73 | 89 | .451 | 22.0 |
| Houston | 72 | 90 | .444 | 23.0 |
| Pittsburgh | 69 | 93 | .426 | 26.0 |
| Chi Cubs | 65 | 97 | .401 | 30.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2000-04-04 | Jason Schmidt | R | 27 | W 2-5 | vs HOU | 1 | 118 | L | 6.0 | 3 | 5 | 5 | 1 | 6 | 4 | 98 | 43 | 55 | 56% | 0-1 | 7.50 | 1.50 |
| 2000-04-05 | Kris Benson | R | 25 | W 2-11 | vs HOU | 1 | 32 | L | 6.0 | 7 | 5 | 2 | 1 | 2 | 6 | 87 | 30 | 57 | 66% | 0-1 | 3.00 | 1.50 |
| 2000-04-06 | Francisco Cordova | R | 28 | L 10-1 | vs HOU | 1 | 96 | W | 8.0 | 2 | 1 | 1 | 0 | 3 | 7 | 107 | 45 | 62 | 58% | 1-0 | 1.13 | 0.63 |
| 2000-04-07 | Todd Ritchie | R | 28 | W 7-2 | @ ARI | 1 | 27 | - | 6.0 | 4 | 1 | 1 | 1 | 0 | 3 | 71 | 25 | 46 | 65% | 0-0 | 1.50 | 0.67 |
| 2000-04-08 | Jimmy Anderson | L | 24 | L 5-6 | @ ARI | 1 | 5 | - | 4.1 | 8 | 5 | 5 | 2 | 2 | 2 | 83 | 40 | 43 | 52% | 0-0 | 11.25 | 2.50 |
| 2000-04-09 | Jason Schmidt | R | 27 | L 0-1 | @ ARI | 2 | 119 | L | 7.0 | 4 | 1 | 1 | 0 | 4 | 5 | 140 | 55 | 85 | 61% | 0-2 | 4.15 | 1.31 |
| 2000-04-11 | Kris Benson | R | 25 | W 3-7 | vs MON | 2 | 33 | L | 7.0 | 9 | 7 | 7 | 3 | 2 | 9 | 103 | 35 | 68 | 66% | 0-2 | 6.23 | 1.54 |
| 2000-04-12 | Francisco Cordova | R | 28 | L 6-4 | vs MON | 2 | 97 | - | 5.1 | 5 | 4 | 3 | 0 | 1 | 2 | 101 | 47 | 54 | 53% | 1-0 | 2.77 | 0.85 |
| 2000-04-13 | Todd Ritchie | R | 28 | L 4-3 | vs MON | 2 | 28 | - | 7.0 | 6 | 2 | 2 | 0 | 1 | 1 | 79 | 31 | 48 | 61% | 0-0 | 2.08 | 0.85 |
| 2000-04-14 | Jason Schmidt | R | 27 | W 5-8 | vs NYN | 3 | 120 | - | 7.0 | 12 | 4 | 4 | 2 | 4 | 6 | 139 | 53 | 86 | 62% | 0-2 | 4.50 | 1.65 |
| 2000-04-15 | Jimmy Anderson | L | 24 | L 2-0 | vs NYN | 2 | 6 | W | 8.0 | 5 | 0 | 0 | 0 | 1 | 5 | 109 | 43 | 66 | 61% | 1-0 | 3.75 | 1.33 |
| 2000-04-16 | Kris Benson | R | 25 | W 9-12 | vs NYN | 3 | 34 | - | 2.2 | 5 | 6 | 3 | 2 | 0 | 1 | 55 | 20 | 35 | 64% | 0-2 | 6.75 | 1.56 |
| 2000-04-18 | Francisco Cordova | R | 28 | L 5-12 | @ FLO | 3 | 98 | L | 4.0 | 8 | 6 | 6 | 0 | 4 | 2 | 92 | 39 | 53 | 58% | 1-1 | 5.29 | 1.35 |
| 2000-04-19 | Todd Ritchie | R | 28 | W 5-1 | @ FLO | 3 | 29 | W | 7.0 | 8 | 1 | 1 | 0 | 1 | 4 | 118 | 44 | 74 | 63% | 1-0 | 1.80 | 1.00 |
| 2000-04-20 | Jimmy Anderson | L | 24 | L 2-3 | @ FLO | 3 | 7 | - | 6.0 | 5 | 2 | 2 | 0 | 2 | 2 | 109 | 49 | 60 | 55% | 1-0 | 3.50 | 1.28 |
| 2000-04-21 | Jose Parra | R | 27 | L 2-6 | @ ATL | 1 | 18 | - | 5.0 | 5 | 2 | 2 | 0 | 2 | 7 | 82 | 32 | 50 | 61% | 0-0 | 3.60 | 1.40 |
| 2000-04-22 | Kris Benson | R | 25 | L 2-4 | @ ATL | 4 | 35 | L | 7.0 | 7 | 3 | 3 | 1 | 2 | 4 | 109 | 42 | 67 | 61% | 0-3 | 5.87 | 1.48 |
| 2000-04-23 | Francisco Cordova | R | 28 | L 3-5 | @ ATL | 4 | 99 | L | 6.2 | 6 | 4 | 2 | 1 | 3 | 6 | 116 | 47 | 69 | 59% | 1-2 | 4.50 | 1.33 |
| 2000-04-25 | Todd Ritchie | R | 28 | L 4-3 | vs SDN | 4 | 30 | - | 7.2 | 9 | 3 | 3 | 0 | 0 | 8 | 106 | 33 | 73 | 69% | 1-0 | 2.25 | 1.04 |
| 2000-04-26 | Jimmy Anderson | L | 24 | L 9-8 | vs SDN | 4 | 8 | - | 4.1 | 7 | 4 | 4 | 0 | 2 | 6 | 85 | 35 | 50 | 59% | 1-0 | 4.30 | 1.39 |
| 2000-04-27 | Jose Parra | R | 27 | W 4-12 | vs SDN | 2 | 19 | L | 2.0 | 7 | 5 | 5 | 1 | 1 | 2 | 42 | 16 | 26 | 62% | 0-1 | 9.00 | 2.14 |
| 2000-04-28 | Kris Benson | R | 25 | L 2-1 | vs CIN | 5 | 36 | W | 8.0 | 5 | 1 | 1 | 0 | 3 | 6 | 103 | 39 | 64 | 62% | 1-3 | 4.65 | 1.35 |
| 2000-04-29 | Francisco Cordova | R | 28 | W 5-6 | vs CIN | 5 | 100 | - | 6.0 | 4 | 4 | 4 | 0 | 2 | 3 | 89 | 34 | 55 | 62% | 1-2 | 4.80 | 1.27 |
| 2000-04-30 | Todd Ritchie | R | 28 | W 2-6 | vs CIN | 5 | 31 | L | 6.2 | 8 | 3 | 3 | 1 | 5 | 4 | 97 | 42 | 55 | 57% | 1-1 | 2.65 | 1.24 |
| 2000-05-02 | Jason Schmidt | R | 27 | W 10-7 | @ SLN | 4 | 121 | - | 4.0 | 3 | 2 | 2 | 1 | 3 | 5 | 75 | 32 | 43 | 57% | 0-2 | 4.50 | 1.63 |
| 2000-05-03 | Kris Benson | R | 25 | W 8-2 | @ SLN | 6 | 37 | W | 7.0 | 5 | 2 | 2 | 0 | 7 | 7 | 129 | 58 | 71 | 55% | 2-3 | 4.26 | 1.42 |
| 2000-05-04 | Francisco Cordova | R | 28 | L 0-5 | @ SLN | 6 | 101 | L | 6.0 | 8 | 5 | 5 | 3 | 0 | 8 | 88 | 35 | 53 | 60% | 1-3 | 5.25 | 1.28 |
| 2000-05-05 | Todd Ritchie | R | 28 | W 4-2 | @ CHN | 6 | 32 | W | 7.1 | 8 | 2 | 2 | 2 | 1 | 8 | 91 | 32 | 59 | 65% | 2-1 | 2.57 | 1.21 |
| 2000-05-06 | Jimmy Anderson | L | 24 | W 11-9 | @ CHN | 5 | 9 | - | 5.0 | 8 | 3 | 3 | 0 | 2 | 3 | 85 | 33 | 52 | 61% | 1-0 | 4.50 | 1.50 |
| 2000-05-07 | Jason Schmidt | R | 27 | W 11-3 | @ CHN | 5 | 122 | W | 5.0 | 4 | 2 | 1 | 0 | 2 | 7 | 101 | 39 | 62 | 61% | 1-2 | 4.03 | 1.55 |
| 2000-05-09 | Kris Benson | R | 26 | W 0-2 | vs NYN | 7 | 38 | L | 8.0 | 8 | 2 | 2 | 2 | 2 | 4 | 114 | 40 | 74 | 65% | 2-4 | 3.91 | 1.39 |
| 2000-05-10 | Todd Ritchie | R | 29 | L 13-9 | vs NYN | 7 | 33 | - | 3.0 | 4 | 6 | 6 | 2 | 1 | 3 | 52 | 23 | 29 | 56% | 2-1 | 3.60 | 1.24 |
| 2000-05-11 | Jimmy Anderson | L | 24 | W 2-3 | vs NYN | 6 | 10 | L | 6.0 | 6 | 3 | 2 | 1 | 3 | 4 | 102 | 45 | 57 | 56% | 1-1 | 4.24 | 1.50 |
| 2000-05-12 | Jason Schmidt | R | 27 | W 1-6 | vs MIL | 6 | 123 | L | 5.0 | 7 | 5 | 5 | 1 | 2 | 2 | 98 | 36 | 62 | 63% | 1-3 | 4.76 | 1.59 |
| 2000-05-13 | Brian O'Connor | L | 23 | L 11-8 | vs MIL | 1 | 1 | - | 2.0 | 7 | 6 | 6 | 1 | 2 | 0 | 52 | 26 | 26 | 50% | 0-0 | 27.00 | 4.50 |
| 2000-05-14 | Kris Benson | R | 26 | L 3-0 | vs MIL | 8 | 39 | W | 8.0 | 4 | 0 | 0 | 0 | 3 | 3 | 109 | 43 | 66 | 61% | 3-4 | 3.33 | 1.31 |
| 2000-05-16 | Todd Ritchie | R | 29 | L 2-6 | @ CIN | 8 | 34 | L | 5.0 | 9 | 3 | 3 | 0 | 1 | 4 | 98 | 33 | 65 | 66% | 2-2 | 3.78 | 1.32 |
| 2000-05-17 | Jimmy Anderson | L | 24 | W 9-6 | @ CIN | 7 | 11 | - | 4.2 | 8 | 4 | 4 | 0 | 2 | 1 | 62 | 25 | 37 | 60% | 1-1 | 4.74 | 1.61 |
| 2000-05-18 | Jason Schmidt | R | 27 | L 3-4 | @ CIN | 7 | 124 | - | 6.0 | 5 | 3 | 3 | 0 | 6 | 3 | 124 | 60 | 64 | 52% | 1-3 | 4.73 | 1.63 |
| 2000-05-19 | Kris Benson | R | 26 | L 13-1 | vs SLN | 9 | 40 | W | 9.0 | 3 | 1 | 1 | 0 | 1 | 11 | 116 | 33 | 83 | 72% | 4-4 | 3.00 | 1.19 |
| 2000-05-20 | Francisco Cordova | R | 28 | W 4-19 | vs SLN | 7 | 102 | L | 3.0 | 5 | 5 | 3 | 1 | 4 | 2 | 67 | 31 | 36 | 54% | 1-4 | 5.54 | 1.41 |
| 2000-05-21 | Todd Ritchie | R | 29 | W 5-7 | vs SLN | 9 | 35 | L | 5.1 | 7 | 5 | 5 | 1 | 4 | 6 | 97 | 41 | 56 | 58% | 2-3 | 4.25 | 1.40 |
| 2000-05-23 | Jimmy Anderson | L | 24 | L 1-6 | @ ARI | 8 | 12 | L | 4.1 | 7 | 6 | 6 | 1 | 2 | 2 | 77 | 34 | 43 | 56% | 1-2 | 5.44 | 1.63 |
| 2000-05-24 | Jason Schmidt | R | 27 | L 5-6 | @ ARI | 8 | 125 | L | 6.1 | 7 | 5 | 5 | 0 | 3 | 7 | 100 | 30 | 70 | 70% | 1-4 | 5.09 | 1.63 |
| 2000-05-25 | Kris Benson | R | 26 | L 5-7 | @ ARI | 10 | 41 | L | 6.0 | 9 | 6 | 5 | 0 | 4 | 7 | 115 | 45 | 70 | 61% | 4-5 | 3.39 | 1.28 |
| 2000-05-26 | Francisco Cordova | R | 28 | W 2-1 | @ COL | 8 | 103 | W | 8.0 | 4 | 1 | 1 | 1 | 1 | 2 | 85 | 31 | 54 | 64% | 2-4 | 4.79 | 1.28 |
| 2000-05-27 | Todd Ritchie | R | 29 | L 6-7 | @ COL | 10 | 36 | - | 4.2 | 6 | 5 | 5 | 1 | 4 | 2 | 88 | 34 | 54 | 61% | 2-3 | 4.65 | 1.45 |
| 2000-05-28 | Jimmy Anderson | L | 24 | L 2-11 | @ COL | 9 | 13 | L | 1.0 | 5 | 5 | 5 | 0 | 0 | 0 | 26 | 11 | 15 | 58% | 1-3 | 6.34 | 1.70 |
| 2000-05-29 | Jason Schmidt | R | 27 | L 10-4 | vs FLO | 9 | 126 | W | 6.2 | 10 | 4 | 4 | 0 | 3 | 4 | 131 | 59 | 72 | 55% | 2-4 | 5.09 | 1.66 |
| 2000-05-30 | Kris Benson | R | 26 | L 3-2 | vs FLO | 11 | 42 | - | 8.0 | 4 | 2 | 2 | 1 | 2 | 11 | 123 | 44 | 79 | 64% | 4-5 | 3.27 | 1.22 |
| 2000-05-31 | Francisco Cordova | R | 28 | L 5-2 | vs FLO | 9 | 104 | W | 6.2 | 10 | 2 | 2 | 1 | 1 | 5 | 94 | 31 | 63 | 67% | 3-4 | 4.50 | 1.31 |
| 2000-06-02 | Todd Ritchie | R | 29 | L 9-3 | vs KCA | 11 | 37 | W | 7.0 | 4 | 3 | 3 | 2 | 2 | 5 | 79 | 27 | 52 | 66% | 3-3 | 4.57 | 1.39 |
| 2000-06-03 | Jason Schmidt | R | 27 | W 3-16 | vs KCA | 10 | 127 | L | 5.1 | 7 | 6 | 7 | 0 | 4 | 6 | 109 | 45 | 64 | 59% | 2-5 | 5.74 | 1.71 |
| 2000-06-04 | Kris Benson | R | 26 | W 5-7 | vs KCA | 12 | 43 | - | 7.0 | 6 | 4 | 4 | 1 | 2 | 5 | 105 | 43 | 62 | 59% | 4-5 | 3.43 | 1.21 |
| 2000-06-05 | Francisco Cordova | R | 28 | L 5-1 | vs DET | 10 | 105 | W | 7.0 | 6 | 1 | 1 | 0 | 2 | 7 | 123 | 48 | 75 | 61% | 4-4 | 4.13 | 1.30 |
| 2000-06-06 | Jimmy Anderson | L | 24 | W 1-2 | vs DET | 10 | 14 | L | 7.0 | 3 | 1 | 1 | 0 | 2 | 3 | 93 | 40 | 53 | 57% | 1-4 | 5.65 | 1.57 |
| 2000-06-07 | Todd Ritchie | R | 29 | L 4-3 | vs DET | 12 | 38 | W | 8.0 | 5 | 2 | 2 | 0 | 2 | 6 | 118 | 47 | 71 | 60% | 4-3 | 4.32 | 1.33 |
| 2000-06-09 | Jason Schmidt | R | 27 | L 5-6 | @ KCA | 11 | 128 | - | 5.0 | 9 | 5 | 1 | 1 | 4 | 2 | 112 | 53 | 59 | 53% | 2-5 | 5.43 | 1.78 |
| 2000-06-10 | Kris Benson | R | 26 | L 1-2 | @ KCA | 13 | 44 | - | 8.0 | 5 | 1 | 1 | 0 | 4 | 6 | 120 | 52 | 68 | 57% | 4-5 | 3.23 | 1.21 |
| 2000-06-11 | Francisco Cordova | R | 28 | W 10-6 | @ KCA | 11 | 106 | - | 6.0 | 7 | 5 | 4 | 0 | 3 | 1 | 109 | 47 | 62 | 57% | 4-4 | 4.30 | 1.33 |
| 2000-06-12 | Todd Ritchie | R | 29 | W 8-10 | vs ATL | 13 | 39 | - | 5.1 | 8 | 6 | 5 | 2 | 1 | 3 | 93 | 35 | 58 | 62% | 4-3 | 4.61 | 1.36 |
| 2000-06-13 | Bronson Arroyo | R | 23 | L 7-6 | vs ATL | 1 | 1 | - | 5.0 | 10 | 5 | 5 | 1 | 2 | 1 | 86 | 36 | 50 | 58% | 0-0 | 9.00 | 2.40 |
| 2000-06-14 | Jimmy Anderson | L | 24 | W 4-8 | vs ATL | 11 | 15 | L | 4.0 | 5 | 6 | 4 | 1 | 5 | 3 | 91 | 46 | 45 | 49% | 1-5 | 5.89 | 1.64 |
| 2000-06-15 | Kris Benson | R | 26 | L 2-0 | vs ATL | 14 | 45 | W | 9.0 | 6 | 0 | 0 | 0 | 2 | 5 | 121 | 44 | 77 | 64% | 5-5 | 2.94 | 1.18 |
| 2000-06-16 | Francisco Cordova | R | 28 | W 3-8 | vs FLO | 12 | 107 | L | 4.1 | 8 | 7 | 6 | 2 | 3 | 4 | 92 | 43 | 49 | 53% | 4-5 | 4.82 | 1.41 |
| 2000-06-17 | Todd Ritchie | R | 29 | W 3-4 | vs FLO | 14 | 40 | - | 6.0 | 7 | 3 | 3 | 1 | 1 | 4 | 102 | 29 | 73 | 72% | 4-3 | 4.60 | 1.36 |
| 2000-06-18 | Bronson Arroyo | R | 23 | W 4-5 | vs FLO | 2 | 2 | - | 5.0 | 8 | 4 | 1 | 0 | 4 | 5 | 84 | 33 | 51 | 61% | 0-0 | 5.40 | 2.40 |
| 2000-06-19 | Jose Silva | R | 26 | L 1-2 | @ MON | 1 | 35 | - | 6.0 | 4 | 0 | 0 | 0 | 0 | 6 | 63 | 21 | 42 | 67% | 5-2 | 2.93 | 1.43 |
| 2000-06-20 | Kris Benson | R | 26 | W 2-1 | @ MON | 15 | 46 | W | 7.1 | 6 | 1 | 1 | 1 | 2 | 4 | 114 | 45 | 69 | 61% | 6-5 | 2.83 | 1.18 |
| 2000-06-21 | Francisco Cordova | R | 28 | W 8-3 | @ MON | 13 | 108 | W | 6.0 | 7 | 2 | 2 | 1 | 3 | 3 | 100 | 38 | 62 | 62% | 5-5 | 4.68 | 1.43 |
| 2000-06-22 | Todd Ritchie | R | 29 | L 5-6 | @ MON | 15 | 41 | L | 6.0 | 5 | 5 | 2 | 1 | 0 | 1 | 77 | 23 | 54 | 70% | 4-4 | 4.50 | 1.33 |
| 2000-06-23 | Bronson Arroyo | R | 23 | L 2-12 | @ NYN | 3 | 3 | L | 2.2 | 9 | 10 | 9 | 1 | 3 | 3 | 71 | 30 | 41 | 58% | 0-1 | 10.38 | 2.77 |
| 2000-06-24 | Jose Silva | R | 27 | L 8-10 | @ NYN | 2 | 36 | - | 5.0 | 6 | 3 | 3 | 1 | 1 | 4 | 76 | 26 | 50 | 66% | 5-2 | 3.18 | 1.43 |
| 2000-06-25 | Kris Benson | R | 26 | L 0-9 | @ NYN | 16 | 47 | L | 6.1 | 8 | 6 | 6 | 0 | 3 | 7 | 118 | 49 | 69 | 58% | 6-6 | 3.16 | 1.21 |
| 2000-06-27 | Todd Ritchie | R | 29 | L 6-0 | vs CHN | 16 | 42 | W | 9.0 | 3 | 0 | 0 | 0 | 3 | 6 | 99 | 39 | 60 | 61% | 5-4 | 4.10 | 1.27 |
| 2000-06-28 | Francisco Cordova | R | 28 | W 4-5 | vs CHN | 14 | 109 | L | 3.2 | 6 | 4 | 4 | 1 | 3 | 4 | 65 | 33 | 32 | 49% | 5-6 | 4.89 | 1.47 |
| 2000-06-29 | Jose Silva | R | 27 | L 5-4 | vs CHN | 3 | 37 | - | 6.0 | 5 | 3 | 2 | 1 | 2 | 2 | 94 | 37 | 57 | 61% | 5-2 | 3.16 | 1.40 |
| 2000-06-30 | Kris Benson | R | 26 | W 8-3 | @ PHI | 17 | 48 | W | 7.0 | 10 | 3 | 3 | 0 | 1 | 3 | 124 | 38 | 86 | 69% | 7-6 | 3.20 | 1.23 |
| 2000-07-01 | Bronson Arroyo | R | 23 | L 3-4 | @ PHI | 4 | 4 | L | 5.2 | 8 | 4 | 4 | 0 | 3 | 4 | 104 | 44 | 60 | 58% | 0-2 | 9.50 | 2.61 |
| 2000-07-02 | Todd Ritchie | R | 29 | L 1-9 | @ PHI | 17 | 43 | L | 3.0 | 8 | 7 | 7 | 2 | 0 | 1 | 51 | 14 | 37 | 73% | 5-5 | 4.59 | 1.31 |
| 2000-07-03 | Francisco Cordova | R | 28 | L 0-3 | @ CHN | 15 | 110 | L | 4.0 | 4 | 1 | 0 | 0 | 0 | 1 | 58 | 21 | 37 | 64% | 5-7 | 4.66 | 1.45 |
| 2000-07-04 | Jose Silva | R | 27 | W 10-4 | @ CHN | 4 | 38 | - | 6.0 | 6 | 4 | 2 | 0 | 4 | 3 | 107 | 42 | 65 | 61% | 5-2 | 3.14 | 1.43 |
| 2000-07-05 | Jimmy Anderson | L | 24 | W 9-6 | @ CHN | 12 | 16 | W | 5.0 | 5 | 4 | 3 | 0 | 3 | 3 | 104 | 47 | 57 | 55% | 2-5 | 5.86 | 1.68 |
| 2000-07-07 | Todd Ritchie | R | 29 | L 8-6 | vs MIN | 18 | 44 | - | 6.0 | 7 | 6 | 1 | 0 | 4 | 6 | 102 | 42 | 60 | 59% | 5-5 | 4.42 | 1.34 |
| 2000-07-08 | Kris Benson | R | 26 | L 4-1 | vs MIN | 18 | 49 | W | 8.1 | 4 | 1 | 1 | 1 | 2 | 5 | 114 | 45 | 69 | 61% | 8-6 | 3.05 | 1.19 |
| 2000-07-09 | Jose Silva | R | 27 | W 2-3 | vs MIN | 5 | 39 | L | 6.0 | 6 | 3 | 3 | 1 | 3 | 4 | 96 | 38 | 58 | 60% | 5-3 | 3.26 | 1.43 |
| 2000-07-13 | Todd Ritchie | R | 29 | L 3-4 | @ CLE | 19 | 45 | - | 7.0 | 6 | 3 | 3 | 1 | 2 | 4 | 92 | 39 | 53 | 58% | 5-5 | 4.38 | 1.32 |
| 2000-07-14 | Kris Benson | R | 26 | L 3-9 | @ CLE | 19 | 50 | L | 4.0 | 9 | 7 | 7 | 1 | 2 | 6 | 77 | 27 | 50 | 65% | 8-7 | 3.43 | 1.24 |
| 2000-07-15 | Jose Silva | R | 27 | L 4-6 | @ CLE | 6 | 40 | L | 1.2 | 7 | 6 | 6 | 0 | 3 | 1 | 65 | 26 | 39 | 60% | 5-4 | 3.99 | 1.56 |
| 2000-07-16 | Jimmy Anderson | L | 24 | L 3-7 | @ LAN | 13 | 17 | - | 6.2 | 3 | 1 | 0 | 0 | 5 | 2 | 98 | 41 | 57 | 58% | 2-5 | 5.35 | 1.65 |
| 2000-07-17 | Bronson Arroyo | R | 23 | L 6-9 | @ LAN | 5 | 5 | L | 5.1 | 7 | 5 | 4 | 0 | 2 | 5 | 98 | 44 | 54 | 55% | 0-3 | 8.63 | 2.33 |
| 2000-07-18 | Todd Ritchie | R | 29 | W 8-6 | @ LAN | 20 | 46 | - | 2.1 | 9 | 6 | 6 | 0 | 1 | 3 | 65 | 20 | 45 | 69% | 5-5 | 4.76 | 1.39 |
| 2000-07-19 | Kris Benson | R | 26 | L 0-6 | @ MIL | 20 | 51 | L | 6.0 | 5 | 3 | 4 | 0 | 3 | 11 | 99 | 39 | 60 | 61% | 8-8 | 3.54 | 1.24 |
| 2000-07-20 | Jose Silva | R | 27 | W 9-2 | @ MIL | 7 | 41 | W | 8.0 | 4 | 2 | 2 | 1 | 3 | 5 | 112 | 41 | 71 | 63% | 6-4 | 3.81 | 1.49 |
| 2000-07-21 | Jimmy Anderson | L | 24 | L 9-2 | vs PHI | 14 | 18 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 5 | 123 | 50 | 73 | 59% | 3-5 | 4.79 | 1.56 |
| 2000-07-22 | Bronson Arroyo | R | 23 | L 2-1 | vs PHI | 6 | 6 | W | 7.0 | 2 | 0 | 0 | 0 | 3 | 3 | 88 | 33 | 55 | 63% | 1-3 | 6.68 | 1.97 |
| 2000-07-23 | Todd Ritchie | R | 29 | W 1-4 | vs PHI | 21 | 47 | L | 7.0 | 7 | 4 | 4 | 2 | 0 | 5 | 103 | 35 | 68 | 66% | 5-6 | 4.79 | 1.37 |
| 2000-07-25 | Kris Benson | R | 26 | W 1-4 | vs MIL | 21 | 52 | - | 9.0 | 7 | 1 | 1 | 1 | 1 | 9 | 123 | 44 | 79 | 64% | 8-8 | 3.38 | 1.22 |
| 2000-07-26 | Jose Silva | R | 27 | L 5-4 | vs MIL | 8 | 42 | W | 7.0 | 4 | 1 | 0 | 0 | 3 | 8 | 111 | 37 | 74 | 67% | 7-4 | 3.49 | 1.45 |
| 2000-07-27 | Jimmy Anderson | L | 25 | W 3-4 | vs MIL | 15 | 19 | - | 8.0 | 8 | 3 | 3 | 0 | 0 | 4 | 88 | 29 | 59 | 67% | 3-5 | 4.66 | 1.51 |
| 2000-07-28 | Bronson Arroyo | R | 23 | L 16-5 | vs SDN | 7 | 7 | W | 6.0 | 8 | 5 | 3 | 0 | 1 | 5 | 92 | 34 | 58 | 63% | 2-3 | 6.32 | 1.89 |
| 2000-07-29 | Francisco Cordova | R | 28 | L 10-2 | vs SDN | 16 | 111 | W | 5.0 | 3 | 1 | 1 | 0 | 0 | 4 | 59 | 16 | 43 | 73% | 6-7 | 4.50 | 1.40 |
| 2000-07-30 | Kris Benson | R | 26 | W 8-9 | vs SDN | 22 | 53 | - | 6.0 | 6 | 3 | 3 | 0 | 4 | 5 | 117 | 47 | 70 | 60% | 8-8 | 3.43 | 1.24 |
| 2000-08-01 | Jimmy Anderson | L | 25 | L 6-0 | vs LAN | 16 | 20 | W | 8.0 | 5 | 0 | 0 | 0 | 2 | 4 | 123 | 54 | 69 | 56% | 4-5 | 4.26 | 1.45 |
| 2000-08-01 | Bronson Arroyo | R | 23 | W 3-5 | vs LAN | 8 | 8 | - | 6.0 | 4 | 2 | 2 | 1 | 2 | 5 | 98 | 41 | 57 | 58% | 2-3 | 5.86 | 1.77 |
| 2000-08-02 | Jose Silva | R | 27 | W 5-11 | vs LAN | 9 | 43 | L | 2.0 | 6 | 8 | 6 | 1 | 4 | 2 | 77 | 37 | 40 | 52% | 7-5 | 4.03 | 1.53 |
| 2000-08-03 | Francisco Cordova | R | 28 | L 2-10 | @ SFN | 17 | 112 | L | 3.1 | 11 | 7 | 7 | 1 | 2 | 4 | 93 | 34 | 59 | 63% | 6-8 | 5.03 | 1.49 |
| 2000-08-04 | Kris Benson | R | 26 | L 3-5 | @ SFN | 23 | 54 | L | 6.0 | 7 | 4 | 4 | 0 | 5 | 4 | 114 | 52 | 62 | 54% | 8-9 | 3.52 | 1.27 |
| 2000-08-05 | Dan Serafini | L | 27 | W 7-2 | @ SFN | 1 | 19 | W | 6.2 | 8 | 2 | 2 | 1 | 2 | 1 | 87 | 33 | 54 | 62% | 1-0 | 7.20 | 2.10 |
| 2000-08-06 | Bronson Arroyo | R | 23 | L 1-7 | @ SFN | 9 | 9 | L | 2.2 | 7 | 7 | 5 | 0 | 2 | 0 | 67 | 28 | 39 | 58% | 2-4 | 6.60 | 1.89 |
| 2000-08-07 | Jimmy Anderson | L | 25 | W 8-7 | @ COL | 17 | 21 | - | 6.0 | 9 | 5 | 4 | 1 | 1 | 4 | 101 | 39 | 62 | 61% | 4-5 | 4.36 | 1.46 |
| 2000-08-08 | Jose Silva | R | 27 | L 1-6 | @ COL | 10 | 44 | L | 4.2 | 12 | 3 | 3 | 0 | 1 | 1 | 77 | 30 | 47 | 61% | 7-6 | 4.11 | 1.59 |
| 2000-08-09 | Kris Benson | R | 26 | L 3-4 | @ COL | 24 | 55 | - | 7.0 | 7 | 2 | 2 | 1 | 1 | 3 | 103 | 35 | 68 | 66% | 8-9 | 3.48 | 1.26 |
| 2000-08-11 | Dan Serafini | L | 27 | W 1-6 | vs ARI | 2 | 20 | L | 6.2 | 7 | 4 | 4 | 1 | 4 | 3 | 110 | 45 | 65 | 59% | 1-1 | 6.75 | 2.00 |
| 2000-08-12 | Todd Ritchie | R | 29 | L 9-6 | vs ARI | 22 | 48 | - | 5.0 | 7 | 2 | 2 | 0 | 0 | 2 | 75 | 26 | 49 | 65% | 5-6 | 4.74 | 1.37 |
| 2000-08-13 | Jimmy Anderson | L | 25 | W 6-7 | vs ARI | 18 | 22 | - | 2.1 | 8 | 3 | 3 | 0 | 0 | 1 | 48 | 19 | 29 | 60% | 4-5 | 4.50 | 1.50 |
| 2000-08-14 | Jose Silva | R | 27 | L 2-16 | @ HOU | 11 | 45 | L | 2.2 | 9 | 9 | 9 | 0 | 3 | 1 | 78 | 34 | 44 | 56% | 7-7 | 4.83 | 1.66 |
| 2000-08-15 | Kris Benson | R | 26 | L 4-5 | @ HOU | 25 | 56 | L | 6.1 | 6 | 4 | 4 | 2 | 5 | 3 | 110 | 46 | 64 | 58% | 8-10 | 3.57 | 1.28 |
| 2000-08-16 | Dan Serafini | L | 27 | L 10-11 | @ HOU | 3 | 21 | L | 4.1 | 6 | 7 | 7 | 4 | 1 | 2 | 74 | 30 | 44 | 59% | 1-2 | 8.14 | 1.86 |
| 2000-08-18 | Todd Ritchie | R | 29 | W 6-3 | @ CIN | 23 | 49 | W | 7.1 | 5 | 3 | 3 | 1 | 2 | 4 | 93 | 35 | 58 | 62% | 6-6 | 4.66 | 1.34 |
| 2000-08-19 | Jimmy Anderson | L | 25 | L 1-7 | @ CIN | 19 | 23 | L | 7.0 | 6 | 5 | 4 | 0 | 3 | 3 | 94 | 46 | 48 | 51% | 4-6 | 4.54 | 1.49 |
| 2000-08-20 | Jose Silva | R | 27 | W 7-3 | @ CIN | 12 | 46 | W | 5.2 | 8 | 3 | 3 | 0 | 2 | 2 | 95 | 30 | 65 | 68% | 8-7 | 4.86 | 1.68 |
| 2000-08-21 | Kris Benson | R | 26 | L 4-7 | @ SLN | 26 | 57 | L | 3.1 | 7 | 6 | 4 | 1 | 3 | 1 | 81 | 34 | 47 | 58% | 8-11 | 3.71 | 1.32 |
| 2000-08-22 | Dan Serafini | L | 27 | W 6-2 | @ SLN | 4 | 22 | - | 5.0 | 6 | 2 | 2 | 0 | 3 | 5 | 89 | 34 | 55 | 62% | 1-2 | 7.27 | 1.85 |
| 2000-08-23 | Todd Ritchie | R | 29 | L 2-5 | @ SLN | 24 | 50 | L | 6.0 | 7 | 3 | 3 | 1 | 1 | 4 | 92 | 32 | 60 | 65% | 6-7 | 4.66 | 1.34 |
| 2000-08-25 | Jimmy Anderson | L | 25 | W 3-6 | vs COL | 20 | 24 | L | 3.2 | 8 | 5 | 3 | 0 | 1 | 3 | 83 | 29 | 54 | 65% | 4-7 | 4.66 | 1.53 |
| 2000-08-26 | Jose Silva | R | 27 | W 4-11 | vs COL | 13 | 47 | L | 4.0 | 9 | 6 | 5 | 1 | 1 | 3 | 80 | 23 | 57 | 71% | 8-8 | 5.11 | 1.71 |
| 2000-08-27 | Dan Serafini | L | 27 | W 2-9 | vs COL | 5 | 23 | L | 3.2 | 8 | 4 | 4 | 1 | 1 | 2 | 63 | 26 | 37 | 59% | 1-3 | 7.76 | 1.97 |
| 2000-08-28 | Todd Ritchie | R | 29 | W 4-5 | vs SFN | 25 | 51 | - | 7.0 | 6 | 4 | 4 | 0 | 5 | 6 | 111 | 39 | 72 | 65% | 6-7 | 4.68 | 1.35 |
| 2000-08-29 | Kris Benson | R | 26 | L 8-0 | vs SFN | 27 | 58 | W | 8.0 | 1 | 0 | 0 | 0 | 5 | 7 | 119 | 50 | 69 | 58% | 9-11 | 3.55 | 1.29 |
| 2000-08-30 | Jimmy Anderson | L | 25 | W 0-2 | vs SFN | 21 | 25 | L | 6.0 | 4 | 2 | 2 | 1 | 1 | 2 | 86 | 40 | 46 | 53% | 4-8 | 4.58 | 1.49 |
| 2000-08-31 | Jose Silva | R | 27 | W 2-10 | vs SFN | 14 | 48 | L | 3.2 | 10 | 8 | 8 | 2 | 2 | 4 | 78 | 30 | 48 | 62% | 8-9 | 5.58 | 1.76 |
| 2000-09-01 | Dan Serafini | L | 27 | W 3-2 | @ SDN | 6 | 24 | - | 7.1 | 5 | 0 | 0 | 0 | 2 | 4 | 110 | 40 | 70 | 64% | 1-3 | 6.08 | 1.73 |
| 2000-09-02 | Todd Ritchie | R | 29 | W 6-3 | @ SDN | 26 | 52 | W | 6.0 | 7 | 3 | 3 | 1 | 1 | 4 | 85 | 25 | 60 | 71% | 7-7 | 4.67 | 1.35 |
| 2000-09-03 | Kris Benson | R | 26 | W 8-6 | @ SDN | 28 | 59 | - | 6.1 | 13 | 6 | 6 | 1 | 3 | 5 | 112 | 42 | 70 | 63% | 9-11 | 3.70 | 1.33 |
| 2000-09-04 | Jimmy Anderson | L | 25 | W 12-1 | @ LAN | 22 | 26 | W | 9.0 | 10 | 1 | 1 | 0 | 3 | 3 | 128 | 51 | 77 | 60% | 5-8 | 4.32 | 1.49 |
| 2000-09-05 | Jose Silva | R | 27 | W 8-0 | @ LAN | 15 | 49 | W | 7.0 | 5 | 0 | 0 | 0 | 1 | 5 | 102 | 36 | 66 | 65% | 9-9 | 5.24 | 1.70 |
| 2000-09-06 | Dan Serafini | L | 27 | W 8-3 | @ LAN | 7 | 25 | W | 6.2 | 4 | 3 | 2 | 0 | 1 | 4 | 93 | 34 | 59 | 63% | 2-3 | 5.65 | 1.60 |
| 2000-09-08 | Todd Ritchie | R | 29 | L 7-3 | vs CIN | 27 | 53 | W | 6.0 | 5 | 3 | 3 | 1 | 1 | 5 | 115 | 37 | 78 | 68% | 8-7 | 4.66 | 1.34 |
| 2000-09-08 | Bronson Arroyo | R | 24 | L 3-1 | vs CIN | 10 | 10 | - | 5.0 | 4 | 0 | 0 | 0 | 3 | 4 | 77 | 29 | 48 | 62% | 2-5 | 6.68 | 1.82 |
| 2000-09-09 | Kris Benson | R | 26 | W 4-6 | vs CIN | 29 | 60 | L | 7.0 | 12 | 5 | 5 | 2 | 3 | 6 | 105 | 31 | 74 | 70% | 9-12 | 3.80 | 1.36 |
| 2000-09-10 | Jimmy Anderson | L | 25 | W 4-6 | vs CIN | 23 | 27 | L | 6.1 | 6 | 6 | 6 | 2 | 4 | 4 | 99 | 41 | 58 | 59% | 5-9 | 4.50 | 1.49 |
| 2000-09-11 | Jose Silva | R | 27 | W 4-8 | vs SLN | 16 | 50 | - | 2.0 | 5 | 4 | 4 | 1 | 1 | 0 | 40 | 14 | 26 | 65% | 9-9 | 5.46 | 1.73 |
| 2000-09-12 | Dan Serafini | L | 27 | W 1-11 | vs SLN | 8 | 26 | L | 5.0 | 9 | 5 | 5 | 1 | 0 | 2 | 76 | 25 | 51 | 67% | 2-4 | 6.00 | 1.63 |
| 2000-09-13 | Todd Ritchie | R | 29 | W 5-9 | vs SLN | 28 | 54 | L | 5.0 | 9 | 6 | 4 | 0 | 2 | 3 | 83 | 28 | 55 | 66% | 8-8 | 4.74 | 1.36 |
| 2000-09-14 | Bronson Arroyo | R | 24 | L 7-8 | @ HOU | 11 | 11 | - | 3.0 | 5 | 3 | 3 | 1 | 1 | 3 | 51 | 19 | 32 | 63% | 2-5 | 6.78 | 1.83 |
| 2000-09-15 | Jimmy Anderson | L | 25 | L 7-16 | @ HOU | 24 | 28 | - | 3.0 | 7 | 6 | 6 | 1 | 1 | 1 | 62 | 23 | 39 | 63% | 5-9 | 4.80 | 1.51 |
| 2000-09-16 | Jose Silva | R | 27 | L 9-10 | @ HOU | 17 | 51 | - | 3.0 | 5 | 9 | 9 | 2 | 3 | 2 | 65 | 26 | 39 | 60% | 9-9 | 6.00 | 1.75 |
| 2000-09-17 | Dan Serafini | L | 27 | L 3-5 | @ HOU | 9 | 27 | L | 5.2 | 7 | 4 | 4 | 1 | 3 | 2 | 87 | 40 | 47 | 54% | 2-5 | 6.00 | 1.63 |
| 2000-09-18 | Todd Ritchie | R | 29 | W 6-5 | @ PHI | 29 | 55 | - | 6.0 | 9 | 4 | 4 | 1 | 2 | 2 | 123 | 51 | 72 | 59% | 8-8 | 4.78 | 1.38 |
| 2000-09-19 | Bronson Arroyo | R | 24 | W 12-8 | @ PHI | 12 | 12 | - | 4.1 | 1 | 2 | 2 | 0 | 1 | 4 | 63 | 26 | 37 | 59% | 2-5 | 6.46 | 1.72 |
| 2000-09-20 | Kris Benson | R | 26 | W 7-6 | @ PHI | 30 | 61 | - | 7.0 | 4 | 4 | 3 | 1 | 2 | 2 | 108 | 50 | 58 | 54% | 9-12 | 3.80 | 1.34 |
| 2000-09-21 | Jimmy Anderson | L | 25 | L 2-12 | @ MIL | 25 | 29 | L | 2.1 | 8 | 5 | 5 | 1 | 1 | 0 | 41 | 16 | 25 | 61% | 5-10 | 5.05 | 1.55 |
| 2000-09-23 | Jose Silva | R | 27 | W 4-2 | @ MIL | 18 | 52 | W | 7.0 | 4 | 2 | 2 | 0 | 2 | 4 | 114 | 43 | 71 | 62% | 10-9 | 5.81 | 1.70 |
| 2000-09-23 | Dan Serafini | L | 27 | L 4-5 | @ MIL | 10 | 28 | - | 7.0 | 2 | 0 | 0 | 0 | 7 | 5 | 125 | 53 | 72 | 58% | 2-5 | 5.31 | 1.59 |
| 2000-09-24 | Todd Ritchie | R | 29 | L 5-8 | @ MIL | 30 | 56 | - | 5.1 | 6 | 5 | 5 | 1 | 2 | 4 | 92 | 36 | 56 | 61% | 8-8 | 4.90 | 1.38 |
| 2000-09-26 | Kris Benson | R | 26 | L 9-4 | vs HOU | 31 | 62 | W | 7.0 | 4 | 2 | 2 | 1 | 3 | 9 | 115 | 48 | 67 | 58% | 10-12 | 3.76 | 1.33 |
| 2000-09-27 | Jimmy Anderson | L | 25 | W 1-10 | vs HOU | 26 | 30 | L | 5.0 | 6 | 6 | 6 | 2 | 5 | 3 | 88 | 40 | 48 | 55% | 5-11 | 5.25 | 1.58 |
| 2000-09-28 | Jose Silva | R | 27 | L 3-2 | vs HOU | 19 | 53 | W | 9.0 | 10 | 2 | 2 | 0 | 2 | 4 | 120 | 47 | 73 | 61% | 11-9 | 5.56 | 1.68 |
| 2000-09-29 | Dan Serafini | L | 27 | L 8-4 | vs CHN | 11 | 29 | - | 4.1 | 8 | 4 | 4 | 0 | 2 | 2 | 72 | 26 | 46 | 64% | 2-5 | 5.54 | 1.65 |
| 2000-09-30 | Todd Ritchie | R | 29 | L 4-2 | vs CHN | 31 | 57 | W | 7.0 | 9 | 2 | 2 | 1 | 1 | 3 | 100 | 34 | 66 | 66% | 9-8 | 4.81 | 1.39 |
| 2000-10-01 | Kris Benson | R | 26 | W 9-10 | vs CHN | 32 | 63 | - | 5.0 | 7 | 5 | 4 | 0 | 2 | 9 | 106 | 39 | 67 | 63% | 10-12 | 3.84 | 1.34 |