| 25 | Tommy John | - | 26 | 33 | 33 | 187.2 | 4.03 | 1.38 | 10.17 | 0.58 | 2.25 | 3.02 | 0.75 | 2.32 | 19 | 6 | 736 | .288 | 802 | -- | -- | -- | -- |
| 26 | Rick Rhoden | - | 37 | 30 | 29 | 181.2 | 3.86 | 1.35 | 9.12 | 1.09 | 3.02 | 5.30 | 0.57 | 1.15 | 15 | 3 | 687 | .268 | 764 | 0.01 | 100.0 | 0.0 | 0.0 |
| 41 | Charles Hudson | - | 66 | 35 | 16 | 154.2 | 3.61 | 1.25 | 7.97 | 1.11 | 3.32 | 5.82 | 0.57 | 0.64 | 6 | 3 | 573 | .239 | 641 | -- | -- | -- | -- |
| 45 | Dennis Rasmussen | - | 71 | 26 | 25 | 146.0 | 4.75 | 1.37 | 8.94 | 1.91 | 3.39 | 5.49 | 0.62 | 0.62 | 11 | 4 | 558 | .260 | 627 | -- | -- | -- | -- |
| 49 | Ron Guidry | - | - | 22 | 17 | 117.2 | 3.67 | 1.27 | 8.49 | 1.07 | 2.91 | 7.34 | 0.40 | 0.56 | 8 | 1 | 448 | .248 | 493 | -- | -- | -- | -- |
| 19 | Dave Righetti | - | 28 | 60 | 0 | 95.0 | 3.51 | 1.46 | 9.00 | 0.85 | 4.17 | 7.29 | 0.57 | 1.06 | 0 | 2 | 362 | .262 | 419 | -- | -- | -- | -- |
| 43 | Tim Stoddard | - | 69 | 57 | 0 | 92.2 | 3.50 | 1.22 | 8.06 | 1.26 | 2.91 | 7.58 | 0.38 | 0.65 | 0 | 0 | 353 | .235 | 386 | -- | -- | -- | -- |
| 29,38 | Pat Clements | - | 82 | 55 | 0 | 80.0 | 4.95 | 1.51 | 10.24 | 0.45 | 3.37 | 4.05 | 0.83 | 2.40 | 0 | 3 | 304 | .299 | 347 | -- | -- | -- | -- |
| 39 | Joe Niekro | - | 72 | 8 | 8 | 50.2 | 3.55 | 1.16 | 7.11 | 0.71 | 3.37 | 5.33 | 0.63 | 0.82 | 0 | 0 | 0 | -- | 0 | -- | -- | -- | -- |
| 45 | Bill Gullickson | - | - | 8 | 8 | 48.0 | 4.88 | 1.19 | 8.63 | 1.31 | 2.06 | 5.25 | 0.39 | 0.62 | 0 | 0 | 0 | -- | 0 | -- | -- | -- | -- |
| 35 | Steve Trout | - | - | 14 | 9 | 46.1 | 6.60 | 1.90 | 9.91 | 0.78 | 7.19 | 5.24 | 1.37 | 1.61 | 1 | 1 | 186 | .274 | 224 | -- | -- | -- | -- |
| 51,54 | Cecilio Guante | - | - | 23 | 0 | 44.0 | 5.73 | 1.41 | 8.59 | 1.64 | 4.09 | 9.41 | 0.43 | 0.48 | 0 | 1 | 170 | .247 | 195 | -- | -- | -- | -- |
| 29 | Bob Shirley | - | - | 12 | 1 | 34.0 | 4.50 | 1.53 | 9.53 | 1.06 | 4.24 | 3.18 | 1.33 | 0.68 | 0 | 0 | 130 | .277 | 152 | -- | -- | -- | -- |
| 35 | Bob Tewksbury | - | - | 8 | 6 | 33.1 | 6.75 | 1.62 | 12.69 | 1.35 | 1.89 | 3.24 | 0.58 | 1.08 | 1 | 1 | 139 | .338 | 149 | -- | -- | -- | -- |
| 46 | Rich Bordi | - | - | 16 | 1 | 33.0 | 7.64 | 1.64 | 11.45 | 1.91 | 3.27 | 6.27 | 0.52 | 0.71 | 0 | 0 | 136 | .309 | 149 | -- | -- | -- | -- |
| 48 | Neil Allen | - | - | 8 | 1 | 24.2 | 3.65 | 1.34 | 8.39 | 0.73 | 3.65 | 5.84 | 0.63 | 1.11 | 0 | 0 | 95 | .242 | 106 | -- | -- | -- | -- |
| 56 | Al Leiter | - | - | 4 | 4 | 22.2 | 6.35 | 1.72 | 9.53 | 0.79 | 5.96 | 11.12 | 0.54 | 0.81 | 1 | 0 | 88 | .273 | 104 | -- | -- | -- | -- |
| 47 | Pete Filson | - | - | 7 | 2 | 22.0 | 3.27 | 1.59 | 10.64 | 0.82 | 3.68 | 4.09 | 0.90 | 0.51 | 1 | 1 | 87 | .299 | 99 | -- | -- | -- | -- |
| 36,54 | Brad Arnsberg | - | - | 6 | 2 | 19.1 | 5.59 | 1.81 | 10.24 | 2.33 | 6.05 | 6.52 | 0.93 | 0.78 | 1 | 0 | 76 | .289 | 91 | -- | -- | -- | -- |
| 29 | Al Holland | - | - | 3 | 0 | 6.1 | 14.21 | 2.84 | 12.79 | 1.42 | 12.79 | 7.11 | 1.80 | 0.70 | 0 | 0 | 28 | .321 | 37 | -- | -- | -- | -- |
| 64 | Bill Fulton | - | - | 3 | 0 | 4.2 | 11.57 | 2.14 | 17.36 | 7.71 | 1.93 | 3.86 | 0.50 | 1.17 | 0 | 1 | 22 | .409 | 24 | -- | -- | -- | -- |
| 6 | Rick Cerone | - | - | 2 | 0 | 2.0 | 0.00 | 0.50 | 0.00 | -- | 4.50 | 4.50 | 1.00 | 1.50 | 0 | 0 | 6 | .000 | 7 | -- | -- | -- | -- |