| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-03-29 | Thu | BOS | AL | H | D | 1 | W | 6-4 | 9 | box - pbp - pit | W1 | 1-0 | 3 | 4 | 7 | 3:00 | 31,042 | Chris Archer | Chris Sale (L) | Austin Pruitt | Carson Smith | Alex Colome | |
| 2018-03-30 | Fri | BOS | AL | H | N | 2 | L | 0-1 | 9 | box - pbp - pit | L1 | 1-1 | 4 | 6 | 12 | 2:46 | 19,203 | Blake Snell | David Price (L) | David Price | Chaz Roe | Craig Kimbrel | |
| 2018-03-31 | Sat | BOS | AL | H | N | 3 | L | 2-3 | 9 | box - pbp - pit | L2 | 1-2 | 4 | 11 | 20 | 3:21 | 17,838 | Andrew Kittredge | Rick Porcello (R) | Rick Porcello | Andrew Kittredge | Craig Kimbrel | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-04-01 | Sun | BOS | AL | H | D | 4 | L | 1-2 | 9 | box - pbp - pit | L3 | 1-3 | 5 | 12 | 25 | 3:24 | 14,256 | Jacob Faria | Hector Velazquez (R) | Hector Velazquez | Jose Alvarado | Joe Kelly | |
| 2018-04-03 | Tue | NYA | AL | A | D | 5 | L | 4-11 | 9 | box - pbp - pit | L4 | 1-4 | 5 | 14 | 27 | 3:29 | 46,776 | Chris Archer | Jordan Montgomery (L) | Tommy Kahnle | Austin Pruitt | None | |
| 2018-04-04 | Wed | NYA | AL | A | D | 6 | L | 2-7 | 9 | box - pbp - pit | L5 | 1-5 | 5 | 14 | 28 | 2:44 | 40,028 | Blake Snell | Luis Severino (R) | Luis Severino | Blake Snell | None | |
| 2018-04-05 | Thu | BOS | AL | A | D | 7 | L | 2-3 | 12 | box - pbp - pit | L6 | 1-6 | 5 | 15 | 29 | 3:55 | 36,134 | Yonny Chirinos | David Price (L) | Bobby Poyner | Andrew Kittredge | None | |
| 2018-04-07 | Sat | BOS | AL | A | D | 8 | L | 3-10 | 9 | box - pbp - pit | L7 | 1-7 | 5 | 15 | 30 | 2:48 | 31,821 | Jacob Faria | Rick Porcello (R) | Rick Porcello | Jacob Faria | None | |
| 2018-04-08 | Sun | BOS | AL | A | D | 9 | L | 7-8 | 9 | box - pbp - pit | L8 | 1-8 | 5 | 15 | 30 | 3:50 | 31,979 | Andrew Kittredge | Eduardo Rodriguez (L) | Carson Smith | Alex Colome | Craig Kimbrel | |
| 2018-04-09 | Mon | CHA | AL | A | D | 10 | W | 5-4 | 9 | box - pbp - pit | W1 | 2-8 | 5 | 15 | 30 | 3:47 | 10,377 | Chris Archer | Miguel Gonzalez (R) | Chris Archer | Miguel Gonzalez | Alex Colome | |
| 2018-04-10 | Tue | CHA | AL | A | D | 11 | W | 6-5 | 9 | box - pbp - pit | W2 | 3-8 | 5 | 15 | 28 | 3:44 | 10,069 | Blake Snell | Carson Fulmer (R) | Blake Snell | Carson Fulmer | Alex Colome | |
| 2018-04-11 | Wed | CHA | AL | A | D | 12 | L | 1-2 | 9 | box - pbp - pit | L1 | 3-9 | 5 | 15 | 28 | 3:02 | 10,431 | Yonny Chirinos | James Shields (R) | Bruce Rondon | Austin Pruitt | Nate Jones | |
| 2018-04-13 | Fri | PHI | NL | H | N | 13 | L | 1-2 | 9 | box - pbp - pit | L2 | 3-10 | 5 | 15 | 29 | 2:53 | 13,372 | Jacob Faria | Vincent Velasquez (R) | Edubray Ramos | Alex Colome | Hector Neris | |
| 2018-04-14 | Sat | PHI | NL | H | N | 14 | L | 4-9 | 9 | box - pbp - pit | L3 | 3-11 | 5 | 15 | 29 | 2:46 | 20,934 | Chris Archer | Jake Arrieta (R) | Jake Arrieta | Chris Archer | None | |
| 2018-04-15 | Sun | PHI | NL | H | D | 15 | L | 4-10 | 9 | box - pbp - pit | L4 | 3-12 | 5 | 15 | 29 | 3:34 | 19,841 | Ryan Yarbrough | Ben Lively (R) | Yacksel Rios | Ryan Yarbrough | None | |
| 2018-04-16 | Mon | TEX | AL | H | N | 16 | W | 8-4 | 9 | box - pbp - pit | W1 | 4-12 | 5 | 14 | 28 | 2:49 | 9,363 | Blake Snell | Martin Perez (L) | Blake Snell | Martin Perez | None | |
| 2018-04-17 | Tue | TEX | AL | H | N | 17 | L | 2-7 | 9 | box - pbp - pit | L1 | 4-13 | 5 | 14 | 28 | 2:44 | 8,972 | Yonny Chirinos | Matt Moore (L) | Matt Moore | Yonny Chirinos | None | |
| 2018-04-18 | Wed | TEX | AL | H | D | 18 | W | 4-2 | 9 | box - pbp - pit | W1 | 5-13 | 5 | 12 | 26 | 2:36 | 8,657 | Jacob Faria | Cole Hamels (L) | Jacob Faria | Cole Hamels | Alex Colome | |
| 2018-04-20 | Fri | MIN | AL | H | N | 19 | W | 8-7 | 10 | box - pbp - pit | W2 | 6-13 | 4 | 12 | 25 | 3:30 | 9,786 | Chris Archer | Lance Lynn (R) | Alex Colome | Zach Duke | None | |
| 2018-04-21 | Sat | MIN | AL | H | N | 20 | W | 10-1 | 9 | box - pbp - pit | W3 | 7-13 | 4 | 11 | 24 | 2:53 | 10,106 | Blake Snell | Kyle Gibson (R) | Blake Snell | Kyle Gibson | None | |
| 2018-04-22 | Sun | MIN | AL | H | D | 21 | W | 8-6 | 9 | box - pbp - pit | W4 | 8-13 | 4 | 11 | 23 | 3:39 | 12,515 | Yonny Chirinos | Phil Hughes (R) | Alex Colome | Addison Reed | None | |
| 2018-04-25 | Wed | BAL | AL | A | N | 22 | W | 8-4 | 9 | box - pbp - pit | W5 | 9-13 | 4 | 11 | 23 | 2:53 | 8,730 | Jacob Faria | Alex Cobb (R) | Andrew Kittredge | Alex Cobb | None | |
| 2018-04-26 | Thu | BAL | AL | A | N | 23 | W | 9-5 | 9 | box - pbp - pit | W6 | 10-13 | 4 | 10 | 22 | 3:20 | 9,596 | Chris Archer | Dylan Bundy (R) | Chris Archer | Dylan Bundy | None | |
| 2018-04-27 | Fri | BOS | AL | A | N | 24 | W | 4-3 | 9 | box - pbp - pit | W7 | 11-13 | 4 | 9 | 20 | 3:10 | 32,620 | Blake Snell | Drew Pomeranz (L) | Blake Snell | Drew Pomeranz | Alex Colome | |
| 2018-04-28 | Sat | BOS | AL | A | D | 25 | W | 12-6 | 9 | box - pbp - pit | W8 | 12-13 | 4 | 9 | 19 | 3:52 | 35,795 | Yonny Chirinos | David Price (L) | Ryan Yarbrough | David Price | None | |
| 2018-04-29 | Sun | BOS | AL | A | D | 26 | L | 3-4 | 9 | box - pbp - pit | L1 | 12-14 | 4 | 9 | 19 | 3:01 | 32,888 | Matt Andriese | Rick Porcello (R) | Craig Kimbrel | Alex Colome | None | |
| 2018-04-30 | Mon | DET | AL | A | N | 27 | W | 3-2 | 9 | box - pbp - pit | W1 | 13-14 | 4 | 9 | 19 | 2:52 | 19,398 | Jacob Faria | Jordan Zimmermann (R) | Jacob Faria | Shane Greene | Jose Alvarado | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-05-01 | Tue | DET | AL | A | N | 28 | L | 1-2 | 9 | box - pbp - pit | L1 | 13-15 | 4 | 9 | 20 | 2:28 | 17,255 | Chris Archer | Matt Boyd (L) | Matt Boyd | Chris Archer | Shane Greene | |
| 2018-05-02 | Wed | DET | AL | A | D | 29 | L | 2-3 | 12 | box - pbp - pit | L2 | 13-16 | 4 | 10 | 21 | 3:28 | 20,866 | Blake Snell | Michael Fulmer (R) | Warwick Saupold | Matt Andriese | None | |
| 2018-05-04 | Fri | TOR | AL | H | N | 30 | W | 6-2 | 9 | box - pbp - pit | W1 | 14-16 | 4 | 9 | 21 | 2:39 | 11,117 | Andrew Kittredge | J.A. Happ (L) | Ryan Yarbrough | J.A. Happ | None | |
| 2018-05-05 | Sat | TOR | AL | H | N | 31 | W | 5-3 | 9 | box - pbp - pit | W2 | 15-16 | 4 | 9 | 20 | 2:52 | 16,297 | Jacob Faria | Aaron Sanchez (R) | Jacob Faria | Aaron Sanchez | Alex Colome | |
| 2018-05-06 | Sun | TOR | AL | H | D | 32 | L | 1-2 | 9 | box - pbp - pit | L1 | 15-17 | 4 | 9 | 20 | 2:56 | 14,032 | Chris Archer | Marco Estrada (R) | Ryan Tepera | Alex Colome | Roberto Osuna | |
| 2018-05-08 | Tue | ATL | NL | H | N | 33 | L | 0-1 | 9 | box - pbp - pit | L2 | 15-18 | 4 | 10 | 21 | 2:55 | 15,382 | Blake Snell | Sean Newcomb (L) | Sean Newcomb | Blake Snell | Arodys Vizcaino | |
| 2018-05-09 | Wed | ATL | NL | H | N | 34 | L | 2-5 | 9 | box - pbp - pit | L3 | 15-19 | 4 | 10 | 22 | 2:51 | 12,082 | Ryan Yarbrough | Julio Teheran (R) | Julio Teheran | Ryan Yarbrough | Arodys Vizcaino | |
| 2018-05-11 | Fri | BAL | AL | A | N | 35 | L | 4-9 | 9 | box - pbp - pit | L4 | 15-20 | 4 | 10 | 21 | 2:36 | 28,170 | Jacob Faria | Kevin Gausman (R) | Kevin Gausman | Jacob Faria | Brad Brach | |
| 2018-05-12 | Sat | BAL | AL | A | D | 36 | L | 3-6 | 9 | box - pbp - pit | L5 | 16-21 | 4 | 10 | 21 | 2:27 | 0 | Chris Archer | David Hess (R) | David Hess | Chris Archer | Mychal Givens | |
| 2018-05-12 | Sat | BAL | AL | A | N | 37 | W | 10-3 | 9 | box - pbp - pit | W1 | 16-21 | 4 | 10 | 21 | 2:58 | 24,534 | Matt Andriese | Alex Cobb (R) | Sergio Romo | Alex Cobb | None | |
| 2018-05-13 | Sun | BAL | AL | A | D | 38 | L | 1-17 | 9 | box - pbp - pit | L1 | 16-22 | 4 | 11 | 22 | 3:01 | 25,257 | Blake Snell | Dylan Bundy (R) | Dylan Bundy | Blake Snell | None | |
| 2018-05-14 | Mon | KCA | AL | A | N | 39 | W | 2-1 | 9 | box - pbp - pit | W1 | 17-22 | 4 | 11 | 22 | 2:33 | 14,174 | Ryan Yarbrough | Eric Skoglund (L) | Ryan Yarbrough | Eric Skoglund | Alex Colome | |
| 2018-05-15 | Tue | KCA | AL | A | N | 40 | W | 6-5 | 9 | box - pbp - pit | W2 | 18-22 | 4 | 11 | 22 | 2:53 | 21,500 | Anthony Banda | Ian Kennedy (R) | Jonny Venters | Kelvin Herrera | Alex Colome | |
| 2018-05-16 | Wed | KCA | AL | A | D | 41 | W | 5-3 | 9 | box - pbp - pit | W3 | 19-22 | 4 | 9 | 20 | 2:59 | 19,611 | Jacob Faria | Jason Hammel (R) | Matt Andriese | Jason Hammel | Alex Colome | |
| 2018-05-17 | Thu | ANA | AL | A | N | 42 | W | 7-1 | 9 | box - pbp - pit | W4 | 20-22 | 4 | 9 | 20 | 3:06 | 30,487 | Chris Archer | Tyler Skaggs (L) | Chris Archer | Tyler Skaggs | None | |
| 2018-05-18 | Fri | ANA | AL | A | N | 43 | W | 8-3 | 9 | box - pbp - pit | W5 | 21-22 | 4 | 9 | 18 | 3:32 | 40,067 | Blake Snell | Nick Tropeano (R) | Blake Snell | Nick Tropeano | None | |
| 2018-05-19 | Sat | ANA | AL | A | N | 44 | W | 5-3 | 9 | box - pbp - pit | W6 | 22-22 | 3 | 7 | 17 | 3:00 | 37,232 | Sergio Romo | Andrew Heaney (L) | Ryan Yarbrough | Andrew Heaney | Alex Colome | |
| 2018-05-20 | Sun | ANA | AL | A | D | 45 | L | 2-5 | 9 | box - pbp - pit | L1 | 22-23 | 3 | 7 | 19 | 3:15 | 38,560 | Sergio Romo | Shohei Ohtani (R) | Shohei Ohtani | Matt Andriese | Blake Parker | |
| 2018-05-22 | Tue | BOS | AL | H | N | 46 | L | 2-4 | 9 | box - pbp - pit | L2 | 22-24 | 4 | 9 | 20 | 2:55 | 10,642 | Jacob Faria | Chris Sale (L) | Chris Sale | Jacob Faria | Craig Kimbrel | |
| 2018-05-23 | Wed | BOS | AL | H | N | 47 | L | 1-4 | 9 | box - pbp - pit | L3 | 22-25 | 4 | 9 | 20 | 3:10 | 10,194 | Chris Archer | David Price (L) | Joe Kelly | Alex Colome | Craig Kimbrel | |
| 2018-05-24 | Thu | BOS | AL | H | N | 48 | W | 6-3 | 9 | box - pbp - pit | W1 | 23-25 | 3 | 8 | 19 | 2:58 | 12,468 | Blake Snell | Rick Porcello (R) | Blake Snell | Rick Porcello | Alex Colome | |
| 2018-05-25 | Fri | BAL | AL | H | N | 49 | L | 0-2 | 9 | box - pbp - pit | L1 | 23-26 | 4 | 9 | 20 | 2:47 | 11,354 | Sergio Romo | David Hess (R) | David Hess | Sergio Romo | Brad Brach | |
| 2018-05-26 | Sat | BAL | AL | H | D | 50 | W | 5-1 | 9 | box - pbp - pit | W1 | 24-26 | 3 | 8 | 19 | 2:28 | 14,744 | Ryne Stanek | Andrew Cashner (R) | Anthony Banda | Andrew Cashner | None | |
| 2018-05-27 | Sun | BAL | AL | H | D | 51 | W | 8-3 | 9 | box - pbp - pit | W2 | 25-26 | 3 | 8 | 18 | 3:10 | 13,311 | Sergio Romo | Kevin Gausman (R) | Vidal Nuno | Kevin Gausman | Austin Pruitt | |
| 2018-05-28 | Mon | OAK | AL | A | D | 52 | W | 1-0 | 13 | box - pbp - pit | W3 | 26-26 | 3 | 8 | 18 | 3:55 | 10,881 | Chris Archer | Trevor Cahill (R) | Ryne Stanek | Chris Hatcher | Jonny Venters | |
| 2018-05-29 | Tue | OAK | AL | A | N | 53 | W | 4-3 | 9 | box - pbp - pit | W4 | 27-26 | 3 | 7 | 16 | 2:55 | 7,521 | Blake Snell | Daniel Gossett (R) | Blake Snell | Daniel Gossett | Sergio Romo | |
| 2018-05-30 | Wed | OAK | AL | A | N | 54 | W | 6-0 | 9 | box - pbp - pit | W5 | 28-26 | 3 | 7 | 15 | 2:50 | 6,705 | Nathan Eovaldi | Sean Manaea (L) | Nathan Eovaldi | Sean Manaea | None | |
| 2018-05-31 | Thu | OAK | AL | A | D | 55 | L | 3-7 | 9 | box - pbp - pit | L1 | 28-27 | 3 | 7 | 15 | 2:37 | 12,070 | Ryne Stanek | Daniel Mengden (R) | Daniel Mengden | Ryne Stanek | Blake Treinen | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-06-01 | Fri | SEA | AL | A | N | 56 | L | 3-4 | 13 | box - pbp - pit | L2 | 28-28 | 3 | 8 | 17 | 4:16 | 22,636 | Sergio Romo | Mike Leake (R) | Roenis Elias | Matt Andriese | None | |
| 2018-06-02 | Sat | SEA | AL | A | N | 57 | L | 1-3 | 9 | box - pbp - pit | L3 | 28-29 | 3 | 8 | 17 | 2:57 | 28,599 | Chris Archer | Marco Gonzales (L) | Marco Gonzales | Chris Archer | Edwin Diaz | |
| 2018-06-03 | Sun | SEA | AL | A | D | 58 | L | 1-2 | 9 | box - pbp - pit | L4 | 28-30 | 3 | 8 | 19 | 2:40 | 26,567 | Blake Snell | Felix Hernandez (R) | Felix Hernandez | Jose Alvarado | Edwin Diaz | |
| 2018-06-05 | Tue | WAS | NL | A | N | 59 | L | 2-4 | 9 | box - pbp - pit | L5 | 28-31 | 3 | 8 | 19 | 2:16 | 32,165 | Nathan Eovaldi | Max Scherzer (R) | Max Scherzer | Nathan Eovaldi | Sean Doolittle | |
| 2018-06-06 | Wed | WAS | NL | A | D | 60 | L | 2-11 | 9 | box - pbp - pit | L6 | 28-32 | 3 | 8 | 19 | 2:50 | 33,106 | Jonny Venters | Tanner Roark (R) | Tanner Roark | Jonny Venters | None | |
| 2018-06-07 | Thu | SEA | AL | H | N | 61 | L | 4-5 | 9 | box - pbp - pit | L7 | 28-33 | 3 | 9 | 20 | 2:43 | 10,342 | Ryne Stanek | Mike Leake (R) | Mike Leake | Austin Pruitt | None | |
| 2018-06-08 | Fri | SEA | AL | H | N | 62 | L | 3-4 | 9 | box - pbp - pit | L8 | 28-34 | 3 | 9 | 20 | 2:50 | 12,435 | Wilmer Font | Marco Gonzales (L) | Marco Gonzales | Wilmer Font | Edwin Diaz | |
| 2018-06-09 | Sat | SEA | AL | H | D | 63 | W | 7-3 | 9 | box - pbp - pit | W1 | 29-34 | 3 | 9 | 20 | 2:52 | 12,258 | Blake Snell | Felix Hernandez (R) | Blake Snell | Felix Hernandez | Chaz Roe | |
| 2018-06-10 | Sun | SEA | AL | H | D | 64 | L | 4-5 | 9 | box - pbp - pit | L1 | 29-35 | 4 | 10 | 22 | 2:50 | 10,512 | Nathan Eovaldi | James Paxton (L) | James Paxton | Jose Alvarado | Edwin Diaz | |
| 2018-06-11 | Mon | TOR | AL | H | N | 65 | W | 8-4 | 9 | box - pbp - pit | W1 | 30-35 | 3 | 9 | 20 | 2:34 | 10,769 | Ryan Yarbrough | Sam Gaviglio (R) | Ryan Yarbrough | Sam Gaviglio | None | |
| 2018-06-12 | Tue | TOR | AL | H | N | 66 | W | 4-1 | 9 | box - pbp - pit | W2 | 31-35 | 3 | 8 | 19 | 2:41 | 11,162 | Ryne Stanek | Jaime Garcia (L) | Austin Pruitt | Jaime Garcia | Sergio Romo | |
| 2018-06-13 | Wed | TOR | AL | H | D | 67 | W | 1-0 | 9 | box - pbp - pit | W3 | 32-35 | 3 | 8 | 19 | 3:00 | 10,847 | Wilmer Font | J.A. Happ (L) | Diego Castillo | Ryan Tepera | None | |
| 2018-06-14 | Thu | NYA | AL | A | N | 68 | L | 3-4 | 9 | box - pbp - pit | L1 | 32-36 | 3 | 9 | 20 | 2:49 | 45,066 | Blake Snell | Domingo German (R) | Domingo German | Blake Snell | Aroldis Chapman | |
| 2018-06-15 | Fri | NYA | AL | A | N | 69 | L | 0-5 | 9 | box - pbp - pit | L2 | 32-37 | 3 | 9 | 21 | 2:44 | 45,112 | Nathan Eovaldi | Jonathan Loaisiga (R) | Jonathan Loaisiga | Nathan Eovaldi | None | |
| 2018-06-16 | Sat | NYA | AL | A | D | 70 | L | 1-4 | 9 | box - pbp - pit | L3 | 32-38 | 3 | 10 | 23 | 2:47 | 46,249 | Ryne Stanek | Luis Severino (R) | Luis Severino | Ryan Yarbrough | Aroldis Chapman | |
| 2018-06-17 | Sun | NYA | AL | A | D | 71 | W | 3-1 | 9 | box - pbp - pit | W1 | 33-38 | 3 | 9 | 21 | 2:45 | 46,400 | Wilmer Font | CC Sabathia (L) | Chaz Roe | CC Sabathia | Sergio Romo | |
| 2018-06-18 | Mon | HOU | AL | A | N | 72 | L | 4-5 | 9 | box - pbp - pit | L1 | 33-39 | 4 | 10 | 22 | 2:57 | 34,151 | Ryne Stanek | Gerrit Cole (R) | Collin McHugh | Sergio Romo | None | |
| 2018-06-19 | Tue | HOU | AL | A | N | 73 | W | 2-1 | 9 | box - pbp - pit | W1 | 34-39 | 3 | 9 | 20 | 3:19 | 37,414 | Blake Snell | Justin Verlander (R) | Blake Snell | Hector Rondon | Sergio Romo | |
| 2018-06-20 | Wed | HOU | AL | A | N | 74 | L | 1-5 | 9 | box - pbp - pit | L1 | 34-40 | 4 | 11 | 22 | 2:32 | 43,409 | Nathan Eovaldi | Charlie Morton (R) | Charlie Morton | Nathan Eovaldi | None | |
| 2018-06-22 | Fri | NYA | AL | H | N | 75 | W | 2-1 | 9 | box - pbp - pit | W1 | 35-40 | 3 | 9 | 20 | 3:08 | 27,252 | Ryne Stanek | CC Sabathia (L) | Ryan Yarbrough | CC Sabathia | Sergio Romo | |
| 2018-06-23 | Sat | NYA | AL | H | D | 76 | W | 4-0 | 9 | box - pbp - pit | W2 | 36-40 | 3 | 8 | 18 | 2:39 | 29,831 | Wilmer Font | Sonny Gray (R) | Wilmer Font | Sonny Gray | None | |
| 2018-06-24 | Sun | NYA | AL | H | D | 77 | W | 7-6 | 12 | box - pbp - pit | W3 | 37-40 | 3 | 8 | 18 | 4:16 | 23,667 | Matt Andriese | Domingo German (R) | Ryan Yarbrough | Chasen Shreve | None | |
| 2018-06-25 | Mon | WAS | NL | H | N | 78 | W | 11-0 | 9 | box - pbp - pit | W4 | 38-40 | 3 | 8 | 18 | 2:51 | 13,624 | Blake Snell | Gio Gonzalez (L) | Blake Snell | Gio Gonzalez | None | |
| 2018-06-26 | Tue | WAS | NL | H | D | 79 | W | 1-0 | 9 | box - pbp - pit | W5 | 39-40 | 3 | 8 | 17 | 2:45 | 14,289 | Nathan Eovaldi | Max Scherzer (R) | Nathan Eovaldi | Max Scherzer | Sergio Romo | |
| 2018-06-28 | Thu | HOU | AL | H | N | 80 | L | 0-1 | 9 | box - pbp - pit | L1 | 39-41 | 3 | 8 | 17 | 2:53 | 12,305 | Ryne Stanek | Lance McCullers (R) | Lance McCullers | Ryan Yarbrough | Hector Rondon | |
| 2018-06-29 | Fri | HOU | AL | H | N | 81 | W | 3-2 | 9 | box - pbp - pit | W1 | 40-41 | 3 | 8 | 17 | 2:35 | 15,797 | Wilmer Font | Gerrit Cole (R) | Wilmer Font | Gerrit Cole | Jose Alvarado | |
| 2018-06-30 | Sat | HOU | AL | H | D | 82 | W | 5-2 | 9 | box - pbp - pit | W2 | 41-41 | 3 | 8 | 17 | 2:39 | 18,378 | Ryne Stanek | Justin Verlander (R) | Vidal Nuno | Justin Verlander | Sergio Romo | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-07-01 | Sun | HOU | AL | H | D | 83 | W | 3-2 | 9 | box - pbp - pit | W3 | 42-41 | 3 | 7 | 16 | 2:36 | 19,334 | Blake Snell | Charlie Morton (R) | Blake Snell | Charlie Morton | Sergio Romo | |
| 2018-07-02 | Mon | MIA | NL | A | N | 84 | L | 2-3 | 10 | box - pbp - pit | L1 | 42-42 | 3 | 8 | 17 | 3:05 | 6,004 | Nathan Eovaldi | Wei-Yin Chen (L) | Drew Rucinski | Ryne Stanek | None | |
| 2018-07-03 | Tue | MIA | NL | A | N | 85 | W | 9-6 | 16 | box - pbp - pit | W1 | 43-42 | 3 | 7 | 15 | 5:31 | 6,259 | Ryan Yarbrough | Trevor Richards (R) | Vidal Nuno | Brett Graves | Jose Alvarado | |
| 2018-07-04 | Wed | MIA | NL | A | D | 86 | L | 0-3 | 9 | box - pbp - pit | L1 | 43-43 | 3 | 8 | 17 | 2:28 | 7,572 | Matt Andriese | Jose Urena (R) | Drew Rucinski | Ryan Weber | Brad Ziegler | |
| 2018-07-06 | Fri | NYN | NL | A | N | 87 | L | 1-5 | 9 | box - pbp - pit | L2 | 43-44 | 3 | 8 | 18 | 2:43 | 24,236 | Ryne Stanek | Jacob DeGrom (R) | Jeurys Familia | Chaz Roe | None | |
| 2018-07-07 | Sat | NYN | NL | A | D | 88 | W | 3-0 | 9 | box - pbp - pit | W1 | 44-44 | 3 | 8 | 18 | 2:58 | 32,986 | Blake Snell | Steven Matz (L) | Blake Snell | Steven Matz | Sergio Romo | |
| 2018-07-08 | Sun | NYN | NL | A | D | 89 | W | 9-0 | 9 | box - pbp - pit | W2 | 45-44 | 3 | 7 | 16 | 2:42 | 24,653 | Nathan Eovaldi | Chris Flexen (R) | Nathan Eovaldi | Chris Flexen | None | |
| 2018-07-09 | Mon | DET | AL | H | N | 90 | W | 10-9 | 10 | box - pbp - pit | W3 | 46-44 | 3 | 7 | 16 | 3:55 | 14,229 | Chris Archer | Francisco Liriano (L) | Matt Andriese | Blaine Hardy | None | |
| 2018-07-10 | Tue | DET | AL | H | N | 91 | W | 5-2 | 9 | box - pbp - pit | W4 | 47-44 | 3 | 7 | 14 | 2:25 | 13,478 | Ryne Stanek | Matt Boyd (L) | Jose Alvarado | Matt Boyd | Sergio Romo | |
| 2018-07-11 | Wed | DET | AL | H | D | 92 | W | 4-2 | 9 | box - pbp - pit | W5 | 48-44 | 3 | 7 | 13 | 2:40 | 13,922 | Hunter Wood | Jordan Zimmermann (R) | Ryan Yarbrough | Jordan Zimmermann | Sergio Romo | |
| 2018-07-12 | Thu | MIN | AL | A | N | 93 | L | 1-5 | 9 | box - pbp - pit | L1 | 48-45 | 3 | 7 | 15 | 2:50 | 25,281 | Blake Snell | Kyle Gibson (R) | Kyle Gibson | Blake Snell | Fernando Rodney | |
| 2018-07-13 | Fri | MIN | AL | A | N | 94 | L | 8-11 | 9 | box - pbp - pit | L2 | 48-46 | 3 | 7 | 16 | 3:23 | 28,756 | Nathan Eovaldi | Jake Odorizzi (R) | Trevor Hildenberger | Nathan Eovaldi | None | |
| 2018-07-14 | Sat | MIN | AL | A | D | 95 | W | 19-6 | 9 | box - pbp - pit | W1 | 49-46 | 3 | 7 | 14 | 3:45 | 25,094 | Chris Archer | Jose Berrios (R) | Jaime Schultz | Zach Duke | None | |
| 2018-07-15 | Sun | MIN | AL | A | D | 96 | L | 7-11 | 10 | box - pbp - pit | L1 | 49-47 | 3 | 7 | 15 | 4:38 | 25,561 | Ryne Stanek | Fernando Romero (R) | Alan Busenitz | Matt Andriese | None | |
| 2018-07-20 | Fri | MIA | NL | H | N | 97 | L | 5-6 | 9 | box - pbp - pit | L2 | 49-48 | 3 | 7 | 16 | 2:54 | 13,248 | Nathan Eovaldi | Dan Straily (R) | Dan Straily | Diego Castillo | Adam Conley | |
| 2018-07-21 | Sat | MIA | NL | H | N | 98 | L | 2-3 | 9 | box - pbp - pit | L3 | 49-49 | 3 | 7 | 17 | 2:48 | 13,808 | Ryne Stanek | Pablo Lopez (R) | Pablo Lopez | Ryan Yarbrough | Kyle Barraclough | |
| 2018-07-22 | Sun | MIA | NL | H | D | 99 | W | 6-4 | 9 | box - pbp - pit | W1 | 50-49 | 3 | 7 | 16 | 3:04 | 11,828 | Chris Archer | Trevor Richards (R) | Adam Kolarek | Kyle Barraclough | None | |
| 2018-07-23 | Mon | NYA | AL | H | N | 100 | W | 7-6 | 9 | box - pbp - pit | W2 | 51-49 | 3 | 7 | 15 | 3:26 | 14,670 | Hunter Wood | Luis Severino (R) | Matt Andriese | Luis Severino | Jose Alvarado | |
| 2018-07-24 | Tue | NYA | AL | H | N | 101 | L | 0-4 | 9 | box - pbp - pit | L1 | 51-50 | 3 | 7 | 16 | 2:37 | 19,579 | Yonny Chirinos | Masahiro Tanaka (R) | Masahiro Tanaka | Yonny Chirinos | None | |
| 2018-07-25 | Wed | NYA | AL | H | D | 102 | W | 3-2 | 9 | box - pbp - pit | W1 | 52-50 | 3 | 7 | 15 | 2:46 | 27,372 | Ryne Stanek | Luis Cessa (R) | Diego Castillo | Luis Cessa | Sergio Romo | |
| 2018-07-26 | Thu | BAL | AL | A | N | 103 | W | 4-3 | 9 | box - pbp - pit | W2 | 53-50 | 3 | 7 | 14 | 3:03 | 19,025 | Hunter Wood | Alex Cobb (R) | Ryan Yarbrough | Alex Cobb | Austin Pruitt | |
| 2018-07-27 | Fri | BAL | AL | A | N | 104 | L | 5-15 | 9 | box - pbp - pit | L1 | 53-51 | 3 | 7 | 15 | 3:10 | 15,649 | Chris Archer | Andrew Cashner (R) | Andrew Cashner | Chris Archer | None | |
| 2018-07-28 | Sat | BAL | AL | A | N | 105 | L | 2-11 | 9 | box - pbp - pit | L2 | 53-52 | 3 | 8 | 17 | 2:53 | 21,526 | Ryne Stanek | Kevin Gausman (R) | Kevin Gausman | Ryne Stanek | None | |
| 2018-07-29 | Sun | BAL | AL | A | D | 106 | L | 5-11 | 9 | box - pbp - pit | L3 | 53-53 | 3 | 8 | 17 | 3:05 | 22,454 | Yonny Chirinos | Dylan Bundy (R) | Dylan Bundy | Yonny Chirinos | None | |
| 2018-07-31 | Tue | ANA | AL | H | N | 107 | W | 10-6 | 9 | box - pbp - pit | W1 | 54-53 | 3 | 7 | 15 | 3:17 | 15,858 | Ryne Stanek | Tyler Skaggs (L) | Ryan Yarbrough | Tyler Skaggs | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-08-01 | Wed | ANA | AL | H | N | 108 | W | 7-2 | 9 | box - pbp - pit | W2 | 55-53 | 3 | 7 | 15 | 3:01 | 9,132 | Tyler Glasnow | Nick Tropeano (R) | Jacob Faria | Nick Tropeano | None | |
| 2018-08-02 | Thu | ANA | AL | H | D | 109 | W | 4-2 | 9 | box - pbp - pit | W3 | 56-53 | 3 | 7 | 14 | 2:29 | 10,988 | Hunter Wood | Andrew Heaney (L) | Jalen Beeks | Andrew Heaney | Sergio Romo | |
| 2018-08-03 | Fri | CHA | AL | H | N | 110 | L | 2-3 | 10 | box - pbp - pit | L1 | 56-54 | 3 | 7 | 17 | 3:33 | 16,144 | Ryne Stanek | Lucas Giolito (R) | Tyler Danish | Jose Alvarado | Hector Santiago | |
| 2018-08-04 | Sat | CHA | AL | H | N | 111 | L | 1-2 | 9 | box - pbp - pit | L2 | 56-55 | 3 | 7 | 17 | 2:43 | 21,214 | Blake Snell | Carlos Rodon (L) | Xavier Cedeno | Yonny Chirinos | Thyago Vieira | |
| 2018-08-05 | Sun | CHA | AL | H | D | 112 | L | 7-8 | 9 | box - pbp - pit | L3 | 56-56 | 3 | 7 | 18 | 3:38 | 14,379 | Hunter Wood | James Shields (R) | Hector Santiago | Diego Castillo | None | |
| 2018-08-07 | Tue | BAL | AL | H | N | 113 | W | 4-3 | 9 | box - pbp - pit | W1 | 57-56 | 3 | 7 | 17 | 2:51 | 11,734 | Tyler Glasnow | Alex Cobb (R) | Sergio Romo | Miguel Castro | None | |
| 2018-08-08 | Wed | BAL | AL | H | N | 114 | L | 4-5 | 9 | box - pbp - pit | L1 | 57-57 | 3 | 7 | 17 | 2:52 | 9,474 | Ryne Stanek | Andrew Cashner (R) | Mike Wright | Sergio Romo | Mychal Givens | |
| 2018-08-09 | Thu | BAL | AL | H | N | 115 | W | 5-4 | 9 | box - pbp - pit | W1 | 58-57 | 3 | 7 | 17 | 2:41 | 10,254 | Hunter Wood | David Hess (R) | Yonny Chirinos | Cody Carroll | Sergio Romo | |
| 2018-08-10 | Fri | TOR | AL | A | N | 116 | W | 7-0 | 9 | box - pbp - pit | W2 | 59-57 | 3 | 7 | 16 | 2:27 | 23,082 | Blake Snell | Marco Estrada (R) | Blake Snell | Marco Estrada | None | |
| 2018-08-11 | Sat | TOR | AL | A | D | 117 | W | 3-1 | 9 | box - pbp - pit | W3 | 60-57 | 3 | 7 | 16 | 2:56 | 38,797 | Ryne Stanek | Sam Gaviglio (R) | Diego Castillo | Sam Gaviglio | Sergio Romo | |
| 2018-08-12 | Sun | TOR | AL | A | D | 118 | L | 1-2 | 9 | box - pbp - pit | L1 | 60-58 | 3 | 7 | 16 | 2:34 | 33,746 | Tyler Glasnow | Marcus Stroman (R) | Jaime Garcia | Jose Alvarado | Ken Giles | |
| 2018-08-14 | Tue | NYA | AL | A | N | 119 | L | 1-4 | 9 | box - pbp - pit | L2 | 60-59 | 3 | 7 | 16 | 2:32 | 40,393 | Hunter Wood | J.A. Happ (L) | J.A. Happ | Hunter Wood | Aroldis Chapman | |
| 2018-08-15 | Wed | NYA | AL | A | N | 120 | W | 6-1 | 9 | box - pbp - pit | W1 | 61-59 | 3 | 7 | 15 | 3:17 | 42,716 | Jacob Faria | Luis Cessa (R) | Ryan Yarbrough | Luis Cessa | None | |
| 2018-08-16 | Thu | NYA | AL | A | D | 121 | W | 3-1 | 9 | box - pbp - pit | W2 | 62-59 | 3 | 7 | 15 | 3:22 | 41,033 | Blake Snell | Masahiro Tanaka (R) | Blake Snell | Masahiro Tanaka | Adam Kolarek | |
| 2018-08-17 | Fri | BOS | AL | A | N | 122 | L | 3-7 | 9 | box - pbp - pit | L1 | 62-60 | 3 | 7 | 15 | 2:47 | 37,012 | Ryne Stanek | Brian Johnson (L) | Brian Johnson | Yonny Chirinos | None | |
| 2018-08-18 | Sat | BOS | AL | A | N | 123 | L | 2-5 | 9 | box - pbp - pit | L2 | 62-61 | 3 | 7 | 15 | 2:28 | 36,654 | Tyler Glasnow | David Price (L) | David Price | Tyler Glasnow | Craig Kimbrel | |
| 2018-08-19 | Sun | BOS | AL | A | D | 124 | W | 2-0 | 9 | box - pbp - pit | W1 | 63-61 | 3 | 7 | 15 | 2:47 | 37,242 | Diego Castillo | Hector Velazquez (R) | Jalen Beeks | Hector Velazquez | Sergio Romo | |
| 2018-08-20 | Mon | KCA | AL | H | N | 125 | W | 1-0 | 9 | box - pbp - pit | W2 | 64-61 | 3 | 7 | 15 | 2:49 | 10,036 | Hunter Wood | Jorge Lopez (R) | Ryan Yarbrough | Jorge Lopez | Jose Alvarado | |
| 2018-08-21 | Tue | KCA | AL | H | N | 126 | W | 4-1 | 9 | box - pbp - pit | W3 | 65-61 | 3 | 7 | 15 | 3:03 | 9,402 | Blake Snell | Glenn Sparkman (R) | Blake Snell | Glenn Sparkman | Sergio Romo | |
| 2018-08-22 | Wed | KCA | AL | H | N | 127 | W | 6-3 | 9 | box - pbp - pit | W4 | 66-61 | 3 | 7 | 15 | 2:52 | 8,686 | Ryne Stanek | Jake Junis (R) | Yonny Chirinos | Jake Junis | Sergio Romo | |
| 2018-08-23 | Thu | KCA | AL | H | N | 128 | W | 4-3 | 9 | box - pbp - pit | W5 | 67-61 | 3 | 7 | 15 | 2:51 | 9,088 | Tyler Glasnow | Danny Duffy (L) | Sergio Romo | Brian Flynn | None | |
| 2018-08-24 | Fri | BOS | AL | H | N | 129 | W | 10-3 | 9 | box - pbp - pit | W6 | 68-61 | 3 | 7 | 14 | 3:10 | 19,723 | Diego Castillo | Hector Velazquez (R) | Jalen Beeks | Hector Velazquez | None | |
| 2018-08-25 | Sat | BOS | AL | H | N | 130 | W | 5-1 | 9 | box - pbp - pit | W7 | 69-61 | 3 | 7 | 14 | 2:53 | 25,695 | Ryan Yarbrough | Rick Porcello (R) | Ryne Stanek | Rick Porcello | None | |
| 2018-08-26 | Sun | BOS | AL | H | D | 131 | W | 9-1 | 9 | box - pbp - pit | W8 | 70-61 | 3 | 7 | 14 | 3:05 | 23,448 | Blake Snell | Nathan Eovaldi (R) | Blake Snell | Nathan Eovaldi | None | |
| 2018-08-28 | Tue | ATL | NL | A | N | 132 | L | 5-9 | 9 | box - pbp - pit | L1 | 70-62 | 3 | 7 | 15 | 3:10 | 21,216 | Ryne Stanek | Julio Teheran (R) | Brad Brach | Chaz Roe | None | |
| 2018-08-29 | Wed | ATL | NL | A | N | 133 | W | 8-5 | 9 | box - pbp - pit | W1 | 71-62 | 3 | 7 | 15 | 3:06 | 20,876 | Diego Castillo | Sean Newcomb (L) | Jalen Beeks | Sean Newcomb | Jose Alvarado | |
| 2018-08-31 | Fri | CLE | AL | A | N | 134 | L | 0-3 | 9 | box - pbp - pit | L1 | 71-63 | 3 | 7 | 15 | 2:18 | 25,639 | Tyler Glasnow | Corey Kluber (R) | Corey Kluber | Tyler Glasnow | Brad Hand | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-09-01 | Sat | CLE | AL | A | N | 135 | W | 5-3 | 9 | box - pbp - pit | W1 | 72-63 | 3 | 7 | 14 | 3:13 | 31,816 | Blake Snell | Shane Bieber (R) | Blake Snell | Shane Bieber | Adam Kolarek | |
| 2018-09-02 | Sun | CLE | AL | A | D | 136 | W | 6-4 | 9 | box - pbp - pit | W2 | 73-63 | 3 | 7 | 14 | 3:10 | 26,535 | Diego Castillo | Carlos Carrasco (R) | Ryan Yarbrough | Carlos Carrasco | Jose Alvarado | |
| 2018-09-03 | Mon | TOR | AL | A | N | 137 | W | 7-1 | 9 | box - pbp - pit | W3 | 74-63 | 3 | 7 | 13 | 2:39 | 18,034 | Ryne Stanek | Marcus Stroman (R) | Yonny Chirinos | Marcus Stroman | None | |
| 2018-09-04 | Tue | TOR | AL | A | N | 138 | W | 4-0 | 9 | box - pbp - pit | W4 | 75-63 | 3 | 7 | 13 | 2:38 | 17,594 | Ryne Stanek | Ryan Borucki (L) | Hunter Wood | Ryan Borucki | Sergio Romo | |
| 2018-09-05 | Wed | TOR | AL | A | N | 139 | L | 3-10 | 9 | box - pbp - pit | L1 | 75-64 | 3 | 7 | 14 | 2:42 | 17,872 | Tyler Glasnow | Aaron Sanchez (R) | Aaron Sanchez | Tyler Glasnow | None | |
| 2018-09-07 | Fri | BAL | AL | H | N | 140 | W | 14-2 | 9 | box - pbp - pit | W1 | 76-64 | 3 | 7 | 13 | 3:05 | 12,436 | Blake Snell | Dylan Bundy (R) | Blake Snell | Dylan Bundy | None | |
| 2018-09-08 | Sat | BAL | AL | H | N | 141 | W | 10-5 | 9 | box - pbp - pit | W2 | 77-64 | 3 | 7 | 12 | 3:00 | 10,275 | Diego Castillo | David Hess (R) | Ryan Yarbrough | David Hess | None | |
| 2018-09-09 | Sun | BAL | AL | H | D | 142 | W | 8-3 | 9 | box - pbp - pit | W3 | 78-64 | 3 | 7 | 12 | 2:51 | 13,632 | Ryne Stanek | Josh Rogers (L) | Yonny Chirinos | Josh Rogers | None | |
| 2018-09-10 | Mon | CLE | AL | H | N | 143 | W | 6-5 | 9 | box - pbp - pit | W4 | 79-64 | 3 | 7 | 12 | 3:38 | 12,724 | Diego Castillo | Corey Kluber (R) | Jaime Schultz | Brad Hand | None | |
| 2018-09-11 | Tue | CLE | AL | H | N | 144 | L | 0-2 | 9 | box - pbp - pit | L1 | 79-65 | 3 | 6 | 10 | 2:44 | 10,599 | Tyler Glasnow | Shane Bieber (R) | Shane Bieber | Tyler Glasnow | Cody Allen | |
| 2018-09-12 | Wed | CLE | AL | H | D | 145 | W | 3-1 | 9 | box - pbp - pit | W1 | 80-65 | 3 | 6 | 10 | 2:20 | 10,654 | Blake Snell | Carlos Carrasco (R) | Blake Snell | Carlos Carrasco | Jose Alvarado | |
| 2018-09-14 | Fri | OAK | AL | H | N | 146 | L | 1-2 | 10 | box - pbp - pit | L1 | 80-66 | 3 | 7 | 11 | 3:05 | 11,549 | Diego Castillo | Edwin Jackson (R) | Blake Treinen | Jaime Schultz | None | |
| 2018-09-15 | Sat | OAK | AL | H | N | 147 | W | 7-5 | 9 | box - pbp - pit | W1 | 81-66 | 3 | 7 | 10 | 3:19 | 15,154 | Ryne Stanek | Liam Hendriks (R) | Andrew Kittredge | Jeurys Familia | Sergio Romo | |
| 2018-09-16 | Sun | OAK | AL | H | D | 148 | W | 5-4 | 9 | box - pbp - pit | W2 | 82-66 | 3 | 6 | 9 | 2:59 | 13,197 | Diego Castillo | Mike Fiers (R) | Andrew Kittredge | Michael Fiers | Sergio Romo | |
| 2018-09-17 | Mon | TEX | AL | A | N | 149 | W | 3-0 | 9 | box - pbp - pit | W3 | 83-66 | 3 | 6 | 8 | 2:41 | 21,840 | Tyler Glasnow | Adrian Sampson (R) | Tyler Glasnow | Adrian Sampson | Sergio Romo | |
| 2018-09-18 | Tue | TEX | AL | A | N | 150 | W | 4-0 | 9 | box - pbp - pit | W4 | 84-66 | 3 | 5 | 8 | 3:04 | 23,523 | Blake Snell | Yovani Gallardo (R) | Blake Snell | Yovani Gallardo | None | |
| 2018-09-19 | Wed | TEX | AL | A | D | 151 | W | 9-3 | 9 | box - pbp - pit | W5 | 85-66 | 3 | 5 | 8 | 2:55 | 25,168 | Diego Castillo | Yohander Mendez (L) | Ryan Yarbrough | Yohander Mendez | None | |
| 2018-09-20 | Thu | TOR | AL | A | N | 152 | L | 8-9 | 9 | box - pbp - pit | L1 | 85-67 | 3 | 6 | 7 | 3:13 | 19,478 | Ryne Stanek | Sam Gaviglio (R) | David Paulino | Sergio Romo | None | |
| 2018-09-21 | Fri | TOR | AL | A | N | 153 | W | 11-3 | 9 | box - pbp - pit | W1 | 86-67 | 3 | 5 | 7 | 3:20 | 21,167 | Diego Castillo | Sean Reid-Foley (R) | Jalen Beeks | Sean Reid-Foley | Austin Pruitt | |
| 2018-09-22 | Sat | TOR | AL | A | D | 154 | L | 2-5 | 9 | box - pbp - pit | L1 | 86-68 | 3 | 5 | 9 | 2:44 | 27,648 | Tyler Glasnow | Thomas Pannone (L) | Thomas Pannone | Tyler Glasnow | Ken Giles | |
| 2018-09-23 | Sun | TOR | AL | A | D | 155 | W | 5-2 | 9 | box - pbp - pit | W1 | 87-68 | 3 | 5 | 9 | 2:41 | 23,944 | Blake Snell | Ryan Borucki (L) | Blake Snell | Ryan Borucki | Sergio Romo | |
| 2018-09-24 | Mon | NYA | AL | H | N | 156 | L | 1-4 | 9 | box - pbp - pit | L1 | 87-69 | 3 | 6 | 10 | 3:01 | 13,832 | Diego Castillo | Jonathan Holder (R) | Sonny Gray | Ryan Yarbrough | Zach Britton | |
| 2018-09-25 | Tue | NYA | AL | H | N | 157 | L | 2-9 | 9 | box - pbp - pit | L2 | 87-70 | 3 | 6 | 11 | 3:14 | 10,953 | Jacob Faria | Luis Severino (R) | Luis Severino | Jacob Faria | None | |
| 2018-09-26 | Wed | NYA | AL | H | N | 158 | W | 8-7 | 9 | box - pbp - pit | W1 | 88-70 | 3 | 6 | 10 | 3:52 | 11,325 | Ryne Stanek | Masahiro Tanaka (R) | Yonny Chirinos | Masahiro Tanaka | Sergio Romo | |
| 2018-09-27 | Thu | NYA | AL | H | D | 159 | L | 1-12 | 9 | box - pbp - pit | L1 | 88-71 | 3 | 6 | 11 | 2:49 | 12,349 | Jaime Schultz | CC Sabathia (L) | CC Sabathia | Jaime Schultz | None | |
| 2018-09-28 | Fri | TOR | AL | H | N | 160 | L | 6-7 | 9 | box - pbp - pit | L2 | 88-72 | 3 | 6 | 11 | 3:39 | 12,061 | Tyler Glasnow | Thomas Pannone (L) | Tim Mayza | Jose Alvarado | Ken Giles | |
| 2018-09-29 | Sat | TOR | AL | H | N | 161 | W | 4-3 | 9 | box - pbp - pit | W1 | 89-72 | 3 | 6 | 11 | 2:38 | 13,221 | Blake Snell | Ryan Borucki (L) | Diego Castillo | Ryan Borucki | Sergio Romo | |
| 2018-09-30 | Sun | TOR | AL | H | D | 162 | W | 9-4 | 9 | box - pbp - pit | W2 | 90-72 | 3 | 6 | 11 | 3:06 | 13,313 | Ryne Stanek | Sam Gaviglio (R) | Ryan Yarbrough | Sam Gaviglio | Austin Pruitt |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 162 | 90 | 72 | .556 | 716 | 646 | +70 |
| Home Games | 81 | 51 | 30 | .630 | 371 | 284 | +87 |
| Away Games | 81 | 39 | 42 | .481 | 345 | 362 | -17 |
| Night Games | 100 | 54 | 46 | .540 | 445 | 387 | +58 |
| Day Games | 62 | 36 | 26 | .581 | 271 | 259 | +12 |
| March/April | 27 | 13 | 14 | .481 | 127 | 132 | -5 |
| May | 28 | 15 | 13 | .536 | 106 | 101 | +5 |
| June | 27 | 13 | 14 | .481 | 87 | 83 | +4 |
| July | 25 | 13 | 12 | .520 | 130 | 136 | -6 |
| August | 27 | 17 | 10 | .630 | 114 | 79 | +35 |
| Sept/Oct | 28 | 19 | 9 | .679 | 152 | 115 | +37 |
| 1-Run Games | 59 | 28 | 31 | .475 | 201 | 204 | -3 |
| Close Games (1-2-3 Runs) | 104 | 56 | 48 | .538 | 366 | 348 | +18 |
| Blowouts (7+ runs) | 19 | 10 | 9 | .526 | 133 | 125 | +8 |
| Extra Innings | 12 | 5 | 7 | .417 | 54 | 57 | -3 |
| Shutouts | 23 | 14 | 9 | .609 | 57 | 22 | +35 |
| vs LHSP | 47 | 27 | 20 | .574 | 200 | 165 | +35 |
| vs RHSP | 115 | 63 | 52 | .548 | 516 | 481 | +35 |
| vs Division | 76 | 41 | 35 | .539 | 342 | 332 | +10 |
| vs League | 142 | 83 | 59 | .585 | 639 | 560 | +79 |
| InterLeague | 20 | 7 | 13 | .350 | 77 | 86 | -9 |
