| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-04-05 | Mon | SDN | NL | H | D | 1 | W | 6-3 | 9 | box - pbp - pit | W1 | 1-0 | 1 | 1 | 12 | 2:31 | 49,192 | Dan Haren | Jon Garland (R) | Dan Haren | Jon Garland | None | |
| 2010-04-06 | Tue | SDN | NL | H | N | 2 | L | 3-6 | 9 | box - pbp - pit | L1 | 1-1 | 3 | 7 | 15 | 3:20 | 19,177 | Edwin Jackson | Chris Young (R) | Chris Young | Edwin Jackson | Heath Bell | |
| 2010-04-07 | Wed | SDN | NL | H | N | 3 | W | 5-3 | 9 | box - pbp - pit | W1 | 2-1 | 1 | 2 | 8 | 2:54 | 17,673 | Ian Kennedy | Kevin Correia (R) | Blaine Boyer | Kevin Correia | Chad Qualls | |
| 2010-04-09 | Fri | PIT | NL | H | N | 4 | W | 9-1 | 9 | box - pbp - pit | W2 | 3-1 | 1 | 1 | 7 | 2:51 | 21,316 | Rodrigo Lopez | Charlie Morton (R) | Rodrigo Lopez | Charlie Morton | None | |
| 2010-04-10 | Sat | PIT | NL | H | N | 5 | L | 3-6 | 9 | box - pbp - pit | L1 | 3-2 | 1 | 2 | 12 | 2:45 | 22,400 | Dan Haren | Zach Duke (L) | Zach Duke | Dan Haren | Octavio Dotel | |
| 2010-04-11 | Sun | PIT | NL | H | D | 6 | W | 15-6 | 9 | box - pbp - pit | W1 | 3-3 | 2 | 6 | 16 | 2:56 | 21,093 | Edwin Jackson | Daniel McCutchen (R) | Edwin Jackson | Daniel McCutchen | None | |
| 2010-04-13 | Tue | LAN | NL | A | D | 7 | L | 5-9 | 9 | box - pbp - pit | L1 | 3-4 | 2 | 8 | 19 | 3:42 | 56,000 | Ian Kennedy | Clayton Kershaw (L) | Clayton Kershaw | Ian Kennedy | None | |
| 2010-04-14 | Wed | LAN | NL | A | N | 8 | W | 9-7 | 11 | box - pbp - pit | W1 | 4-4 | 2 | 8 | 18 | 4:57 | 44,621 | Rodrigo Lopez | Chad Billingsley (R) | Leo Rosales | Russ Ortiz | None | |
| 2010-04-15 | Thu | LAN | NL | A | N | 9 | L | 5-6 | 10 | box - pbp - pit | L1 | 4-5 | 2 | 14 | 17 | 3:42 | 39,697 | Dan Haren | Hiroki Kuroda (R) | Jonathan Broxton | Blaine Boyer | None | |
| 2010-04-16 | Fri | SDN | NL | A | N | 10 | L | 3-6 | 9 | box - pbp - pit | L2 | 4-6 | 2 | 14 | 18 | 3:20 | 26,632 | Edwin Jackson | Jon Garland (R) | Heath Bell | Juan Gutierrez | None | |
| 2010-04-17 | Sat | SDN | NL | A | N | 11 | L | 0-5 | 9 | box - pbp - pit | L3 | 4-7 | 3 | 15 | 23 | 3:06 | 31,324 | Kris Benson | Kevin Correia (R) | Kevin Correia | Kris Benson | None | |
| 2010-04-18 | Sun | SDN | NL | A | D | 12 | L | 3-5 | 9 | box - pbp - pit | L4 | 4-8 | 5 | 16 | 24 | 3:03 | 20,634 | Ian Kennedy | Wade LeBlanc (L) | Edward Mujica | Aaron Heilman | Heath Bell | |
| 2010-04-19 | Mon | SLN | NL | H | N | 13 | L | 2-4 | 9 | box - pbp - pit | L5 | 4-9 | 5 | 16 | 29 | 3:08 | 24,167 | Rodrigo Lopez | Brad Penny (R) | Brad Penny | Blaine Boyer | Ryan Franklin | |
| 2010-04-20 | Tue | SLN | NL | H | N | 14 | W | 9-7 | 9 | box - pbp - pit | W1 | 5-9 | 4 | 16 | 27 | 3:04 | 19,855 | Dan Haren | Kyle Lohse (R) | Dan Haren | Mitchell Boggs | Chad Qualls | |
| 2010-04-21 | Wed | SLN | NL | H | N | 15 | L | 4-9 | 9 | box - pbp - pit | L1 | 5-10 | 4 | 16 | 29 | 2:50 | 19,165 | Edwin Jackson | Chris Carpenter (R) | Jason Motte | Chad Qualls | None | |
| 2010-04-23 | Fri | PHI | NL | H | N | 16 | W | 7-4 | 9 | box - pbp - pit | W1 | 6-10 | 3 | 16 | 27 | 2:54 | 25,980 | Kris Benson | Cole Hamels (L) | Kris Benson | Cole Hamels | Chad Qualls | |
| 2010-04-24 | Sat | PHI | NL | H | N | 17 | L | 2-3 | 9 | box - pbp - pit | L1 | 6-11 | 5 | 16 | 28 | 2:35 | 33,323 | Ian Kennedy | Nelson Figueroa (R) | Jose Contreras | Juan Gutierrez | Ryan Madson | |
| 2010-04-25 | Sun | PHI | NL | H | D | 18 | W | 8-6 | 9 | box - pbp - pit | W1 | 7-11 | 4 | 16 | 28 | 3:12 | 29,296 | Rodrigo Lopez | Kyle Kendrick (R) | Leo Rosales | David Herndon | Chad Qualls | |
| 2010-04-26 | Mon | COL | NL | A | N | 19 | W | 5-3 | 9 | box - pbp - pit | W2 | 8-11 | 3 | 14 | 21 | 2:49 | 20,308 | Dan Haren | Jason Hammel (R) | Dan Haren | Jason Hammel | Chad Qualls | |
| 2010-04-27 | Tue | COL | NL | A | N | 20 | L | 1-12 | 9 | box - pbp - pit | L1 | 8-12 | 4 | 16 | 26 | 2:52 | 24,112 | Edwin Jackson | Ubaldo Jimenez (R) | Ubaldo Jimenez | Edwin Jackson | None | |
| 2010-04-28 | Wed | COL | NL | A | D | 21 | W | 12-11 | 10 | box - pbp - pit | W1 | 9-12 | 3 | 11 | 21 | 4:08 | 23,773 | Kris Benson | Greg Smith (L) | Bob Howry | Franklin Morales | Juan Gutierrez | |
| 2010-04-29 | Thu | CHN | NL | A | D | 22 | W | 13-5 | 9 | box - pbp - pit | W2 | 9-13 | 3 | 13 | 25 | 2:40 | 36,850 | Ian Kennedy | Ted Lilly (L) | Ian Kennedy | Ted Lilly | None | |
| 2010-04-30 | Fri | CHN | NL | A | D | 23 | L | 5-11 | 9 | box - pbp - pit | L1 | 10-13 | 3 | 11 | 22 | 3:02 | 37,800 | Rodrigo Lopez | Randy Wells (R) | Randy Wells | Rodrigo Lopez | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-05-01 | Sat | CHN | NL | A | D | 24 | L | 5-7 | 9 | box - pbp - pit | L2 | 10-14 | 3 | 12 | 23 | 3:06 | 40,368 | Dan Haren | Carlos Silva (R) | Sean Marshall | Juan Gutierrez | Carlos Marmol | |
| 2010-05-02 | Sun | CHN | NL | A | D | 25 | L | 5-10 | 9 | box - pbp - pit | L3 | 11-14 | 3 | 12 | 23 | 2:41 | 38,144 | Edwin Jackson | Tom Gorzelanny (L) | Tom Gorzelanny | Edwin Jackson | None | |
| 2010-05-03 | Mon | HOU | NL | A | N | 26 | W | 9-1 | 9 | box - pbp - pit | W1 | 12-14 | 3 | 12 | 22 | 3:16 | 20,370 | Cesar Valdez | Felipe Paulino (R) | Cesar Valdez | Felipe Paulino | None | |
| 2010-05-04 | Tue | HOU | NL | A | N | 27 | W | 1-0 | 9 | box - pbp - pit | W2 | 13-14 | 3 | 10 | 19 | 2:40 | 22,661 | Ian Kennedy | Roy Oswalt (R) | Ian Kennedy | Roy Oswalt | Chad Qualls | |
| 2010-05-05 | Wed | HOU | NL | A | N | 28 | L | 2-4 | 9 | box - pbp - pit | L1 | 13-15 | 4 | 12 | 22 | 2:24 | 21,030 | Rodrigo Lopez | Brett Myers (R) | Matt Lindstrom | Juan Gutierrez | None | |
| 2010-05-06 | Thu | HOU | NL | A | N | 29 | W | 6-3 | 9 | box - pbp - pit | W1 | 14-15 | 4 | 10 | 19 | 2:32 | 21,019 | Dan Haren | Wandy Rodriguez (L) | Dan Haren | Wandy Rodriguez | None | |
| 2010-05-07 | Fri | MIL | NL | H | N | 30 | L | 2-3 | 9 | box - pbp - pit | L1 | 14-16 | 4 | 11 | 20 | 2:45 | 27,067 | Edwin Jackson | Yovani Gallardo (R) | Yovani Gallardo | Edwin Jackson | Trevor Hoffman | |
| 2010-05-08 | Sat | MIL | NL | H | N | 31 | L | 3-17 | 9 | box - pbp - pit | L2 | 15-16 | 4 | 10 | 19 | 3:20 | 26,877 | Cesar Valdez | Randy Wolf (L) | Randy Wolf | Cesar Valdez | None | |
| 2010-05-09 | Sun | MIL | NL | H | D | 32 | L | 1-6 | 9 | box - pbp - pit | L3 | 15-17 | 4 | 10 | 19 | 3:14 | 25,358 | Ian Kennedy | Chris Narveson (L) | Chris Narveson | Ian Kennedy | None | |
| 2010-05-10 | Mon | LAN | NL | H | N | 33 | L | 3-7 | 9 | box - pbp - pit | L4 | 15-18 | 4 | 12 | 22 | 2:59 | 19,863 | Rodrigo Lopez | Chad Billingsley (R) | Chad Billingsley | Rodrigo Lopez | None | |
| 2010-05-11 | Tue | LAN | NL | H | N | 34 | L | 3-13 | 9 | box - pbp - pit | L5 | 16-18 | 4 | 11 | 21 | 3:20 | 21,030 | Dan Haren | John Ely (R) | John Ely | Dan Haren | None | |
| 2010-05-12 | Wed | LAN | NL | H | N | 35 | L | 3-6 | 9 | box - pbp - pit | L6 | 16-19 | 4 | 12 | 22 | 3:13 | 22,714 | Edwin Jackson | Hiroki Kuroda (R) | Hiroki Kuroda | Edwin Jackson | Jonathan Broxton | |
| 2010-05-14 | Fri | ATL | NL | A | N | 36 | L | 5-6 | 9 | box - pbp - pit | L7 | 16-20 | 4 | 12 | 22 | 3:24 | 30,657 | Ian Kennedy | Kenshin Kawakami (R) | Billy Wagner | Chad Qualls | None | |
| 2010-05-15 | Sat | ATL | NL | A | N | 37 | W | 11-1 | 9 | box - pbp - pit | W1 | 17-20 | 5 | 13 | 23 | 2:54 | 32,718 | Rodrigo Lopez | Tommy Hanson (R) | Rodrigo Lopez | Tommy Hanson | None | |
| 2010-05-16 | Sun | ATL | NL | A | D | 38 | L | 1-13 | 9 | box - pbp - pit | L1 | 17-21 | 5 | 13 | 23 | 3:02 | 31,758 | Dan Haren | Tim Hudson (R) | Tim Hudson | Dan Haren | None | |
| 2010-05-17 | Mon | FLO | NL | A | N | 39 | W | 5-1 | 9 | box - pbp - pit | W1 | 18-21 | 5 | 13 | 22 | 2:48 | 10,870 | Edwin Jackson | Chris Volstad (R) | Edwin Jackson | Chris Volstad | None | |
| 2010-05-18 | Tue | FLO | NL | A | D | 40 | L | 0-8 | 9 | box - pbp - pit | L1 | 18-22 | 5 | 13 | 23 | 2:47 | 13,289 | Billy Buckner | Josh Johnson (R) | Josh Johnson | Billy Buckner | None | |
| 2010-05-19 | Wed | SFN | NL | H | N | 41 | W | 13-1 | 9 | box - pbp - pit | W1 | 19-22 | 4 | 12 | 22 | 2:46 | 17,073 | Ian Kennedy | Todd Wellemeyer (R) | Ian Kennedy | Todd Wellemeyer | None | |
| 2010-05-20 | Thu | SFN | NL | H | N | 42 | W | 8-7 | 9 | box - pbp - pit | W2 | 20-22 | 4 | 12 | 21 | 3:14 | 18,607 | Rodrigo Lopez | Tim Lincecum (R) | Aaron Heilman | Jeremy Affeldt | Chad Qualls | |
| 2010-05-21 | Fri | TOR | AL | H | N | 43 | W | 8-6 | 9 | box - pbp - pit | W3 | 21-22 | 4 | 11 | 19 | 2:50 | 19,531 | Dan Haren | Brandon Morrow (R) | Dan Haren | Brandon Morrow | Chad Qualls | |
| 2010-05-22 | Sat | TOR | AL | H | N | 44 | W | 8-5 | 9 | box - pbp - pit | W4 | 22-22 | 4 | 11 | 20 | 2:34 | 32,746 | Edwin Jackson | Dana Eveland (L) | Edwin Jackson | Dana Eveland | Chad Qualls | |
| 2010-05-23 | Sun | TOR | AL | H | D | 45 | L | 4-12 | 9 | box - pbp - pit | L1 | 23-22 | 4 | 10 | 17 | 3:02 | 23,148 | Billy Buckner | Shaun Marcum (R) | Shaun Marcum | Billy Buckner | None | |
| 2010-05-25 | Tue | COL | NL | A | N | 46 | L | 2-3 | 9 | box - pbp - pit | L2 | 23-23 | 4 | 10 | 19 | 2:38 | 28,370 | Ian Kennedy | Jhoulys Chacin (R) | Jhoulis Chacin | Ian Kennedy | Manuel Corpas | |
| 2010-05-26 | Wed | COL | NL | A | N | 47 | L | 3-7 | 9 | box - pbp - pit | L3 | 23-24 | 4 | 10 | 20 | 2:30 | 26,320 | Rodrigo Lopez | Ubaldo Jimenez (R) | Ubaldo Jimenez | Rodrigo Lopez | None | |
| 2010-05-27 | Thu | COL | NL | A | D | 48 | L | 2-8 | 9 | box - pbp - pit | L4 | 23-25 | 5 | 11 | 21 | 2:55 | 28,353 | Dan Haren | Jason Hammel (R) | Jason Hammel | Dan Haren | None | |
| 2010-05-28 | Fri | SFN | NL | A | N | 49 | L | 0-5 | 9 | box - pbp - pit | L5 | 23-26 | 5 | 12 | 22 | 2:18 | 31,495 | Edwin Jackson | Matt Cain (R) | Matt Cain | Edwin Jackson | None | |
| 2010-05-29 | Sat | SFN | NL | A | N | 50 | L | 1-12 | 9 | box - pbp - pit | L6 | 23-27 | 5 | 13 | 23 | 3:02 | 37,400 | Billy Buckner | Jonathan Sanchez (L) | Jonathan Sanchez | Billy Buckner | None | |
| 2010-05-30 | Sun | SFN | NL | A | D | 51 | L | 5-6 | 10 | box - pbp - pit | L7 | 23-28 | 5 | 14 | 24 | 3:33 | 41,394 | Ian Kennedy | Todd Wellemeyer (R) | Brian Wilson | Carlos Rosa | None | |
| 2010-05-31 | Mon | LAN | NL | A | N | 52 | L | 4-5 | 9 | box - pbp - pit | L8 | 23-29 | 5 | 14 | 24 | 2:41 | 45,325 | Rodrigo Lopez | Chad Billingsley (R) | Jonathan Broxton | Esmerling Vasquez | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-06-01 | Tue | LAN | NL | A | N | 53 | L | 0-1 | 10 | box - pbp - pit | L9 | 23-30 | 5 | 14 | 24 | 3:06 | 36,533 | Dan Haren | John Ely (R) | Jeff Weaver | Juan Gutierrez | None | |
| 2010-06-02 | Wed | LAN | NL | A | D | 54 | L | 0-1 | 14 | box - pbp - pit | L10 | 23-31 | 5 | 16 | 26 | 4:16 | 35,355 | Edwin Jackson | Carlos Monasterios (R) | Travis Schlichting | Cesar Valdez | None | |
| 2010-06-04 | Fri | COL | NL | H | N | 55 | W | 7-6 | 9 | box - pbp - pit | W1 | 24-31 | 5 | 15 | 25 | 3:31 | 25,290 | Ian Kennedy | Aaron Cook (R) | Chad Qualls | Manuel Corpas | None | |
| 2010-06-05 | Sat | COL | NL | H | N | 56 | W | 4-3 | 9 | box - pbp - pit | W2 | 25-31 | 5 | 14 | 25 | 3:10 | 28,138 | Dontrelle Willis | Jhoulys Chacin (R) | Dontrelle Willis | Jhoulis Chacin | Chad Qualls | |
| 2010-06-06 | Sun | COL | NL | H | D | 57 | L | 2-3 | 9 | box - pbp - pit | L1 | 25-32 | 5 | 15 | 25 | 2:40 | 20,793 | Rodrigo Lopez | Ubaldo Jimenez (R) | Ubaldo Jimenez | Rodrigo Lopez | Manuel Corpas | |
| 2010-06-07 | Mon | ATL | NL | H | N | 58 | W | 7-4 | 9 | box - pbp - pit | W1 | 26-32 | 5 | 15 | 25 | 3:15 | 17,731 | Dan Haren | Derek Lowe (R) | Dan Haren | Derek Lowe | Chad Qualls | |
| 2010-06-08 | Tue | ATL | NL | H | N | 59 | L | 5-7 | 9 | box - pbp - pit | L1 | 26-33 | 5 | 15 | 25 | 3:05 | 17,052 | Edwin Jackson | Kris Medlen (R) | Jonny Venters | Esmerling Vasquez | Billy Wagner | |
| 2010-06-09 | Wed | ATL | NL | H | N | 60 | W | 2-1 | 9 | box - pbp - pit | W1 | 27-33 | 5 | 15 | 24 | 3:05 | 19,138 | Ian Kennedy | Kenshin Kawakami (R) | Aaron Heilman | Peter Moylan | Chad Qualls | |
| 2010-06-10 | Thu | ATL | NL | H | D | 61 | L | 7-11 | 9 | box - pbp - pit | L1 | 28-33 | 4 | 11 | 20 | 3:53 | 26,969 | Dontrelle Willis | Tommy Hanson (R) | Peter Moylan | Chad Qualls | None | |
| 2010-06-11 | Fri | SLN | NL | H | N | 62 | L | 2-5 | 9 | box - pbp - pit | L2 | 28-34 | 5 | 14 | 23 | 3:05 | 20,629 | Rodrigo Lopez | Jaime Garcia (L) | Jaime Garcia | Rodrigo Lopez | Ryan Franklin | |
| 2010-06-12 | Sat | SLN | NL | H | N | 63 | W | 7-2 | 9 | box - pbp - pit | W1 | 29-34 | 5 | 11 | 21 | 2:28 | 30,017 | Dan Haren | Adam Ottavino (R) | Dan Haren | Adam Ottavino | None | |
| 2010-06-13 | Sun | SLN | NL | H | D | 64 | W | 7-5 | 9 | box - pbp - pit | W2 | 30-34 | 4 | 10 | 19 | 3:15 | 23,922 | Edwin Jackson | Chris Carpenter (R) | Esmerling Vasquez | Kyle McClellan | None | |
| 2010-06-15 | Tue | BOS | AL | A | N | 65 | L | 3-6 | 9 | box - pbp - pit | L1 | 30-35 | 4 | 10 | 19 | 3:02 | 37,459 | Ian Kennedy | Clay Buchholz (R) | Clay Buchholz | Ian Kennedy | Jonathan Papelbon | |
| 2010-06-16 | Wed | BOS | AL | A | N | 66 | L | 2-6 | 9 | box - pbp - pit | L2 | 30-36 | 4 | 12 | 22 | 2:48 | 37,452 | Rodrigo Lopez | Jon Lester (L) | Jon Lester | Rodrigo Lopez | Jonathan Papelbon | |
| 2010-06-17 | Thu | BOS | AL | A | N | 67 | L | 5-8 | 9 | box - pbp - pit | L3 | 30-37 | 5 | 13 | 23 | 3:24 | 37,544 | Dan Haren | John Lackey (R) | John Lackey | Dan Haren | None | |
| 2010-06-18 | Fri | DET | AL | A | N | 68 | L | 5-7 | 9 | box - pbp - pit | L4 | 30-38 | 5 | 14 | 24 | 2:58 | 37,438 | Dontrelle Willis | Armando Galarraga (R) | Phil Coke | Chad Qualls | Jose Valverde | |
| 2010-06-19 | Sat | DET | AL | A | N | 69 | W | 6-5 | 9 | box - pbp - pit | W1 | 31-38 | 5 | 12 | 23 | 2:50 | 40,681 | Edwin Jackson | Rick Porcello (R) | Edwin Jackson | Rick Porcello | Aaron Heilman | |
| 2010-06-20 | Sun | DET | AL | A | D | 70 | L | 1-3 | 9 | box - pbp - pit | L1 | 31-39 | 5 | 13 | 24 | 2:35 | 41,417 | Ian Kennedy | Max Scherzer (R) | Max Scherzer | Ian Kennedy | Jose Valverde | |
| 2010-06-21 | Mon | NYA | AL | H | N | 71 | W | 10-4 | 9 | box - pbp - pit | W1 | 31-40 | 5 | 14 | 24 | 2:59 | 47,229 | Rodrigo Lopez | A.J. Burnett (R) | Rodrigo Lopez | A.J. Burnett | None | |
| 2010-06-22 | Tue | NYA | AL | H | N | 72 | L | 3-9 | 9 | box - pbp - pit | L1 | 31-41 | 5 | 14 | 24 | 3:06 | 45,776 | Dan Haren | Andy Pettitte (L) | Andy Pettitte | Dan Haren | None | |
| 2010-06-23 | Wed | NYA | AL | H | N | 73 | L | 5-6 | 10 | box - pbp - pit | L2 | 31-42 | 5 | 15 | 26 | 4:07 | 46,325 | Dontrelle Willis | Javier Vazquez (R) | Mariano Rivera | Carlos Rosa | None | |
| 2010-06-25 | Fri | TBA | AL | A | N | 74 | W | 1-0 | 9 | box - pbp - pit | W1 | 32-42 | 5 | 15 | 25 | 2:46 | 18,918 | Edwin Jackson | Jeff Niemann (R) | Edwin Jackson | Jeff Niemann | None | |
| 2010-06-26 | Sat | TBA | AL | A | D | 75 | L | 3-5 | 9 | box - pbp - pit | L1 | 32-43 | 5 | 15 | 26 | 3:01 | 23,945 | Ian Kennedy | David Price (L) | David Price | Ian Kennedy | Rafael Soriano | |
| 2010-06-27 | Sun | TBA | AL | A | D | 76 | W | 2-1 | 9 | box - pbp - pit | W1 | 33-43 | 5 | 15 | 25 | 2:46 | 25,442 | Rodrigo Lopez | Wade Davis (R) | Rodrigo Lopez | Wade Davis | Aaron Heilman | |
| 2010-06-28 | Mon | SLN | NL | A | N | 77 | L | 5-6 | 9 | box - pbp - pit | L1 | 33-44 | 5 | 15 | 25 | 2:41 | 41,578 | Dan Haren | Chris Carpenter (R) | Jason Motte | Aaron Heilman | None | |
| 2010-06-29 | Tue | SLN | NL | A | N | 78 | L | 0-8 | 9 | box - pbp - pit | L2 | 33-45 | 5 | 15 | 27 | 2:51 | 38,736 | Dontrelle Willis | Adam Wainwright (R) | Adam Wainwright | Dontrelle Willis | None | |
| 2010-06-30 | Wed | SLN | NL | A | D | 79 | W | 4-2 | 9 | box - pbp - pit | W1 | 34-45 | 5 | 15 | 27 | 3:53 | 36,962 | Barry Enright | Jeff Suppan (R) | Barry Enright | Jeff Suppan | Aaron Heilman | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-07-02 | Fri | LAN | NL | H | N | 80 | W | 12-5 | 9 | box - pbp - pit | W2 | 34-46 | 5 | 16 | 28 | 3:15 | 23,155 | Edwin Jackson | Hiroki Kuroda (R) | Edwin Jackson | Hiroki Kuroda | None | |
| 2010-07-03 | Sat | LAN | NL | H | N | 81 | L | 1-14 | 9 | box - pbp - pit | L1 | 34-47 | 5 | 16 | 29 | 3:11 | 44,169 | Rodrigo Lopez | Clayton Kershaw (L) | Clayton Kershaw | Rodrigo Lopez | None | |
| 2010-07-04 | Sun | LAN | NL | H | D | 82 | L | 1-3 | 9 | box - pbp - pit | L2 | 34-48 | 5 | 16 | 29 | 2:57 | 26,517 | Dan Haren | Chad Billingsley (R) | Hong-Chih Kuo | Aaron Heilman | Jonathan Broxton | |
| 2010-07-05 | Mon | CHN | NL | H | D | 83 | L | 4-9 | 9 | box - pbp - pit | L3 | 34-49 | 5 | 16 | 29 | 3:07 | 26,250 | Ian Kennedy | Tom Gorzelanny (L) | Tom Gorzelanny | Ian Kennedy | None | |
| 2010-07-06 | Tue | CHN | NL | H | N | 84 | L | 4-6 | 9 | box - pbp - pit | L4 | 34-50 | 5 | 16 | 29 | 2:43 | 20,067 | Barry Enright | Carlos Silva (R) | Carlos Silva | Barry Enright | Carlos Marmol | |
| 2010-07-07 | Wed | CHN | NL | H | N | 85 | L | 3-8 | 9 | box - pbp - pit | L5 | 34-51 | 5 | 16 | 29 | 3:03 | 20,914 | Edwin Jackson | Ryan Dempster (R) | Ryan Dempster | Edwin Jackson | None | |
| 2010-07-08 | Thu | FLO | NL | H | N | 86 | W | 10-4 | 9 | box - pbp - pit | W1 | 34-52 | 5 | 16 | 29 | 2:46 | 16,664 | Rodrigo Lopez | Anibal Sanchez (R) | Rodrigo Lopez | Anibal Sanchez | None | |
| 2010-07-09 | Fri | FLO | NL | H | N | 87 | L | 2-3 | 9 | box - pbp - pit | L1 | 34-53 | 5 | 16 | 29 | 2:42 | 18,117 | Dan Haren | Ricky Nolasco (R) | Ricky Nolasco | Dan Haren | Leo Nunez | |
| 2010-07-10 | Sat | FLO | NL | H | N | 88 | W | 5-4 | 9 | box - pbp - pit | W1 | 35-53 | 5 | 16 | 29 | 2:51 | 21,627 | Ian Kennedy | Nate Robertson (R) | Ian Kennedy | Nate Robertson | Juan Gutierrez | |
| 2010-07-11 | Sun | FLO | NL | H | D | 89 | L | 0-2 | 9 | box - pbp - pit | L1 | 35-54 | 5 | 16 | 29 | 2:34 | 21,037 | Barry Enright | Alex Sanabia (R) | Burke Badenhop | Barry Enright | Leo Nunez | |
| 2010-07-16 | Fri | SDN | NL | A | N | 90 | L | 1-12 | 9 | box - pbp - pit | L2 | 35-55 | 5 | 16 | 29 | 3:13 | 33,177 | Dan Haren | Jon Garland (R) | Jon Garland | Dan Haren | None | |
| 2010-07-17 | Sat | SDN | NL | A | N | 91 | L | 5-8 | 9 | box - pbp - pit | L3 | 35-56 | 5 | 16 | 29 | 2:43 | 40,011 | Rodrigo Lopez | Clayton Richard (L) | Clayton Richard | Rodrigo Lopez | Heath Bell | |
| 2010-07-18 | Sun | SDN | NL | A | D | 92 | L | 4-6 | 9 | box - pbp - pit | L4 | 35-57 | 5 | 16 | 29 | 3:17 | 25,363 | Edwin Jackson | Kevin Correia (R) | Kevin Correia | Edwin Jackson | Heath Bell | |
| 2010-07-19 | Mon | NYN | NL | H | N | 93 | W | 13-2 | 9 | box - pbp - pit | W1 | 35-58 | 5 | 16 | 29 | 3:20 | 18,253 | Ian Kennedy | Mike Pelfrey (R) | Ian Kennedy | Mike Pelfrey | None | |
| 2010-07-20 | Tue | NYN | NL | H | N | 94 | W | 3-2 | 9 | box - pbp - pit | W2 | 36-58 | 5 | 16 | 29 | 2:23 | 18,749 | Barry Enright | R.A. Dickey (R) | Barry Enright | R.A. Dickey | Juan Gutierrez | |
| 2010-07-21 | Wed | NYN | NL | H | N | 95 | W | 4-3 | 14 | box - pbp - pit | W3 | 37-58 | 5 | 16 | 29 | 4:45 | 18,223 | Dan Haren | Jon Niese (L) | Blaine Boyer | Fernando Nieve | None | |
| 2010-07-22 | Thu | SFN | NL | H | N | 96 | L | 0-3 | 9 | box - pbp - pit | L1 | 37-59 | 5 | 16 | 29 | 2:27 | 17,230 | Rodrigo Lopez | Matt Cain (R) | Matt Cain | Rodrigo Lopez | Brian Wilson | |
| 2010-07-23 | Fri | SFN | NL | H | N | 97 | L | 4-7 | 9 | box - pbp - pit | L2 | 37-60 | 5 | 16 | 29 | 3:45 | 22,512 | Edwin Jackson | Jonathan Sanchez (L) | Chris Ray | Edwin Jackson | Brian Wilson | |
| 2010-07-24 | Sat | SFN | NL | H | N | 98 | L | 4-10 | 9 | box - pbp - pit | L3 | 38-60 | 5 | 16 | 29 | 3:02 | 32,774 | Ian Kennedy | Madison Bumgarner (L) | Madison Bumgarner | Ian Kennedy | None | |
| 2010-07-25 | Sun | SFN | NL | H | D | 99 | L | 2-3 | 10 | box - pbp - pit | L4 | 38-61 | 5 | 16 | 29 | 3:15 | 31,278 | Barry Enright | Tim Lincecum (R) | Sergio Romo | Esmerling Vasquez | Brian Wilson | |
| 2010-07-27 | Tue | PHI | NL | A | N | 100 | L | 5-9 | 9 | box - pbp - pit | L5 | 38-62 | 5 | 16 | 29 | 3:13 | 44,379 | Rodrigo Lopez | Cole Hamels (L) | David Herndon | Jordan Norberto | None | |
| 2010-07-28 | Wed | PHI | NL | A | N | 101 | L | 1-7 | 9 | box - pbp - pit | L6 | 38-63 | 5 | 16 | 29 | 2:42 | 45,048 | Edwin Jackson | Roy Halladay (R) | Roy Halladay | Edwin Jackson | None | |
| 2010-07-29 | Thu | PHI | NL | A | N | 102 | L | 2-3 | 11 | box - pbp - pit | L7 | 38-64 | 5 | 16 | 29 | 3:17 | 45,232 | Joe Saunders | Kyle Kendrick (R) | Jose Contreras | Esmerling Vasquez | None | |
| 2010-07-30 | Fri | NYN | NL | A | N | 103 | W | 9-6 | 9 | box - pbp - pit | W1 | 39-64 | 5 | 16 | 29 | 3:27 | 34,280 | Ian Kennedy | Mike Pelfrey (R) | Ian Kennedy | Raul Valdes | Aaron Heilman | |
| 2010-07-31 | Sat | NYN | NL | A | N | 104 | L | 4-5 | 9 | box - pbp - pit | L1 | 39-65 | 5 | 16 | 29 | 3:12 | 35,287 | Barry Enright | Hisanori Takahashi (L) | Francisco Rodriguez | Juan Gutierrez | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-08-01 | Sun | NYN | NL | A | D | 105 | W | 14-1 | 9 | box - pbp - pit | W1 | 40-65 | 5 | 16 | 28 | 2:41 | 35,014 | Daniel Hudson | Jon Niese (L) | Daniel Hudson | Jonathon Niese | None | |
| 2010-08-02 | Mon | WAS | NL | H | N | 106 | L | 1-3 | 9 | box - pbp - pit | L1 | 40-66 | 5 | 16 | 29 | 2:19 | 16,793 | Rodrigo Lopez | Livan Hernandez (R) | Livan Hernandez | Rodrigo Lopez | Sean Burnett | |
| 2010-08-03 | Tue | WAS | NL | H | N | 107 | W | 6-1 | 9 | box - pbp - pit | W1 | 41-66 | 5 | 16 | 28 | 2:22 | 17,164 | Joe Saunders | Scott Olsen (L) | Joe Saunders | Scott Olsen | None | |
| 2010-08-04 | Wed | WAS | NL | H | N | 108 | L | 2-7 | 9 | box - pbp - pit | L1 | 41-67 | 5 | 16 | 29 | 3:16 | 15,670 | Ian Kennedy | Craig Stammen (R) | Craig Stammen | Ian Kennedy | None | |
| 2010-08-05 | Thu | WAS | NL | H | N | 109 | W | 8-4 | 9 | box - pbp - pit | W1 | 42-67 | 5 | 16 | 28 | 2:53 | 16,638 | Barry Enright | Ross Detwiler (L) | Barry Enright | Ross Detwiler | None | |
| 2010-08-06 | Fri | SDN | NL | H | N | 110 | W | 2-1 | 9 | box - pbp - pit | W2 | 43-67 | 5 | 15 | 27 | 2:23 | 22,168 | Daniel Hudson | Jon Garland (R) | Daniel Hudson | Jon Garland | Aaron Heilman | |
| 2010-08-07 | Sat | SDN | NL | H | N | 111 | W | 6-5 | 9 | box - pbp - pit | W3 | 44-67 | 5 | 15 | 27 | 3:04 | 48,946 | Rodrigo Lopez | Clayton Richard (L) | Aaron Heilman | Luke Gregerson | None | |
| 2010-08-08 | Sun | SDN | NL | H | D | 112 | L | 1-10 | 9 | box - pbp - pit | L1 | 44-68 | 5 | 15 | 27 | 2:46 | 27,856 | Joe Saunders | Mat Latos (R) | Mat Latos | Joe Saunders | None | |
| 2010-08-09 | Mon | MIL | NL | A | N | 113 | W | 7-4 | 10 | box - pbp - pit | W1 | 45-68 | 5 | 15 | 27 | 3:26 | 29,633 | Ian Kennedy | Chris Narveson (L) | Sam Demel | Trevor Hoffman | Aaron Heilman | |
| 2010-08-10 | Tue | MIL | NL | A | N | 114 | W | 2-1 | 9 | box - pbp - pit | W2 | 46-68 | 5 | 15 | 27 | 3:02 | 35,029 | Barry Enright | Manny Parra (L) | Blaine Boyer | Chris Capuano | Sam Demel | |
| 2010-08-11 | Wed | MIL | NL | A | N | 115 | W | 8-2 | 9 | box - pbp - pit | W3 | 47-68 | 5 | 15 | 27 | 3:00 | 29,611 | Daniel Hudson | David Bush (R) | Daniel Hudson | David Bush | None | |
| 2010-08-12 | Thu | MIL | NL | A | D | 116 | L | 4-8 | 9 | box - pbp - pit | L1 | 47-69 | 5 | 15 | 27 | 3:14 | 34,808 | Rodrigo Lopez | Randy Wolf (L) | Randy Wolf | Rodrigo Lopez | John Axford | |
| 2010-08-13 | Fri | WAS | NL | A | N | 117 | L | 2-4 | 9 | box - pbp - pit | L2 | 47-70 | 5 | 15 | 28 | 2:25 | 19,549 | Joe Saunders | John Lannan (L) | John Lannan | Joe Saunders | Sean Burnett | |
| 2010-08-14 | Sat | WAS | NL | A | N | 118 | W | 9-2 | 9 | box - pbp - pit | W1 | 48-70 | 5 | 15 | 28 | 2:43 | 22,400 | Ian Kennedy | Jason Marquis (R) | Ian Kennedy | Jason Marquis | None | |
| 2010-08-15 | Sun | WAS | NL | A | D | 119 | L | 3-5 | 9 | box - pbp - pit | L1 | 48-71 | 5 | 15 | 28 | 2:33 | 21,695 | Barry Enright | Stephen Strasburg (R) | Tyler Clippard | Jordan Norberto | Drew Storen | |
| 2010-08-17 | Tue | CIN | NL | H | N | 120 | L | 2-6 | 9 | box - pbp - pit | L2 | 48-72 | 5 | 15 | 28 | 2:45 | 21,502 | Daniel Hudson | Bronson Arroyo (R) | Bronson Arroyo | Daniel Hudson | None | |
| 2010-08-18 | Wed | CIN | NL | H | N | 121 | L | 7-11 | 9 | box - pbp - pit | L3 | 49-72 | 5 | 15 | 28 | 3:25 | 15,509 | Rodrigo Lopez | Edinson Volquez (R) | Arthur Rhodes | Aaron Heilman | None | |
| 2010-08-19 | Thu | CIN | NL | H | N | 122 | L | 5-9 | 9 | box - pbp - pit | L4 | 49-73 | 5 | 15 | 28 | 2:50 | 17,385 | Joe Saunders | Travis Wood (L) | Travis Wood | Joe Saunders | None | |
| 2010-08-20 | Fri | COL | NL | H | N | 123 | W | 4-3 | 10 | box - pbp - pit | W1 | 50-73 | 5 | 15 | 28 | 3:22 | 26,294 | Ian Kennedy | Esmil Rogers (R) | Aaron Heilman | Joe Beimel | None | |
| 2010-08-21 | Sat | COL | NL | H | N | 124 | W | 3-1 | 9 | box - pbp - pit | W2 | 51-73 | 5 | 15 | 28 | 2:45 | 37,631 | Barry Enright | Ubaldo Jimenez (R) | Barry Enright | Ubaldo Jimenez | Juan Gutierrez | |
| 2010-08-22 | Sun | COL | NL | H | D | 125 | L | 0-1 | 9 | box - pbp - pit | L1 | 51-74 | 5 | 15 | 28 | 2:33 | 30,397 | Daniel Hudson | Jhoulys Chacin (R) | Jhoulis Chacin | Aaron Heilman | Huston Street | |
| 2010-08-24 | Tue | SDN | NL | A | N | 126 | L | 0-5 | 9 | box - pbp - pit | L2 | 51-75 | 5 | 15 | 28 | 2:45 | 20,075 | Rodrigo Lopez | Clayton Richard (L) | Clayton Richard | Rodrigo Lopez | None | |
| 2010-08-25 | Wed | SDN | NL | A | N | 127 | L | 3-9 | 9 | box - pbp - pit | L3 | 51-76 | 5 | 15 | 28 | 2:32 | 21,966 | Joe Saunders | Wade LeBlanc (L) | Wade LeBlanc | Joe Saunders | None | |
| 2010-08-26 | Thu | SDN | NL | A | D | 128 | W | 11-5 | 9 | box - pbp - pit | W1 | 51-77 | 5 | 15 | 28 | 3:02 | 20,983 | Ian Kennedy | Kevin Correia (R) | Ian Kennedy | Kevin Correia | None | |
| 2010-08-27 | Fri | SFN | NL | A | N | 129 | W | 6-0 | 9 | box - pbp - pit | W2 | 52-77 | 5 | 15 | 28 | 2:45 | 38,013 | Barry Enright | Tim Lincecum (R) | Barry Enright | Tim Lincecum | None | |
| 2010-08-28 | Sat | SFN | NL | A | N | 130 | W | 11-3 | 9 | box - pbp - pit | W3 | 52-78 | 5 | 15 | 28 | 2:48 | 41,250 | Daniel Hudson | Barry Zito (L) | Daniel Hudson | Barry Zito | None | |
| 2010-08-29 | Sun | SFN | NL | A | D | 131 | L | 7-9 | 9 | box - pbp - pit | L1 | 52-79 | 5 | 15 | 29 | 3:03 | 38,735 | Rodrigo Lopez | Matt Cain (R) | Jeremy Affeldt | Esmerling Vasquez | Brian Wilson | |
| 2010-08-30 | Mon | SDN | NL | H | N | 132 | W | 7-2 | 9 | box - pbp - pit | W1 | 53-79 | 5 | 15 | 28 | 2:22 | 17,829 | Joe Saunders | Wade LeBlanc (L) | Joe Saunders | Wade LeBlanc | None | |
| 2010-08-31 | Tue | SDN | NL | H | N | 133 | W | 7-4 | 9 | box - pbp - pit | W2 | 54-79 | 5 | 15 | 28 | 2:52 | 16,250 | Ian Kennedy | Kevin Correia (R) | Ian Kennedy | Kevin Correia | Juan Gutierrez | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-09-01 | Wed | SDN | NL | H | D | 134 | W | 5-2 | 9 | box - pbp - pit | W3 | 55-79 | 5 | 15 | 27 | 2:31 | 17,599 | Barry Enright | Mat Latos (R) | Barry Enright | Luke Gregerson | Juan Gutierrez | |
| 2010-09-03 | Fri | HOU | NL | H | N | 135 | W | 4-3 | 9 | box - pbp - pit | W4 | 56-79 | 5 | 15 | 27 | 2:40 | 24,748 | Daniel Hudson | Brett Myers (R) | Aaron Heilman | Wilton Lopez | Juan Gutierrez | |
| 2010-09-04 | Sat | HOU | NL | H | N | 136 | L | 5-6 | 9 | box - pbp - pit | L1 | 56-80 | 5 | 15 | 27 | 3:09 | 31,605 | Joe Saunders | Bud Norris (R) | Mark Melancon | Aaron Heilman | Brandon Lyon | |
| 2010-09-05 | Sun | HOU | NL | H | D | 137 | L | 2-3 | 9 | box - pbp - pit | L2 | 56-81 | 5 | 15 | 28 | 2:34 | 25,416 | Rodrigo Lopez | J.A. Happ (L) | J.A. Happ | Rodrigo Lopez | Brandon Lyon | |
| 2010-09-06 | Mon | SFN | NL | H | D | 138 | L | 0-2 | 11 | box - pbp - pit | L3 | 56-82 | 5 | 15 | 29 | 3:02 | 31,879 | Ian Kennedy | Madison Bumgarner (L) | Santiago Casilla | Aaron Heilman | Brian Wilson | |
| 2010-09-07 | Tue | SFN | NL | H | N | 139 | L | 3-6 | 9 | box - pbp - pit | L4 | 56-83 | 5 | 15 | 29 | 2:16 | 19,417 | Barry Enright | Tim Lincecum (R) | Tim Lincecum | Barry Enright | Jeremy Affeldt | |
| 2010-09-08 | Wed | SFN | NL | H | N | 140 | W | 3-1 | 9 | box - pbp - pit | W1 | 57-83 | 5 | 15 | 29 | 2:29 | 19,972 | Daniel Hudson | Barry Zito (L) | Daniel Hudson | Barry Zito | Juan Gutierrez | |
| 2010-09-10 | Fri | COL | NL | A | N | 141 | L | 4-13 | 9 | box - pbp - pit | L1 | 58-83 | 5 | 15 | 28 | 3:07 | 37,265 | Joe Saunders | Jorge De La Rosa (L) | Jorge de la Rosa | Joe Saunders | None | |
| 2010-09-11 | Sat | COL | NL | A | N | 142 | L | 1-2 | 9 | box - pbp - pit | L2 | 58-84 | 5 | 15 | 28 | 2:49 | 48,023 | Rodrigo Lopez | Ubaldo Jimenez (R) | Matt Reynolds | Rodrigo Lopez | Huston Street | |
| 2010-09-12 | Sun | COL | NL | A | D | 143 | L | 2-4 | 9 | box - pbp - pit | L3 | 58-85 | 5 | 15 | 28 | 3:06 | 41,504 | Ian Kennedy | Jhoulys Chacin (R) | Huston Street | Sam Demel | None | |
| 2010-09-13 | Mon | CIN | NL | A | N | 144 | L | 2-7 | 9 | box - pbp - pit | L4 | 58-86 | 5 | 15 | 28 | 3:05 | 12,060 | Barry Enright | Bronson Arroyo (R) | Bronson Arroyo | Barry Enright | None | |
| 2010-09-14 | Tue | CIN | NL | A | N | 145 | W | 3-1 | 9 | box - pbp - pit | W1 | 59-86 | 5 | 15 | 28 | 2:38 | 16,973 | Daniel Hudson | Travis Wood (L) | Daniel Hudson | Travis Wood | Juan Gutierrez | |
| 2010-09-15 | Wed | CIN | NL | A | N | 146 | L | 5-7 | 9 | box - pbp - pit | L1 | 59-87 | 5 | 15 | 28 | 3:02 | 19,923 | Joe Saunders | Homer Bailey (R) | Matt Maloney | Joe Saunders | Francisco Cordero | |
| 2010-09-16 | Thu | CIN | NL | A | D | 147 | W | 3-1 | 9 | box - pbp - pit | W1 | 60-87 | 5 | 15 | 28 | 2:38 | 22,090 | Rodrigo Lopez | Edinson Volquez (R) | Rodrigo Lopez | Edinson Volquez | Juan Gutierrez | |
| 2010-09-17 | Fri | PIT | NL | A | N | 148 | L | 3-4 | 9 | box - pbp - pit | L1 | 60-88 | 5 | 15 | 28 | 2:50 | 22,939 | Ian Kennedy | Brian Burres (L) | Evan Meek | Esmerling Vasquez | None | |
| 2010-09-18 | Sat | PIT | NL | A | N | 149 | L | 6-9 | 9 | box - pbp - pit | L2 | 60-89 | 5 | 15 | 28 | 3:19 | 25,981 | Barry Enright | James McDonald (R) | James McDonald | Barry Enright | None | |
| 2010-09-19 | Sun | PIT | NL | A | D | 150 | L | 3-4 | 9 | box - pbp - pit | L3 | 60-90 | 5 | 15 | 28 | 2:30 | 18,331 | Daniel Hudson | Zach Duke (L) | Joel Hanrahan | Aaron Heilman | Evan Meek | |
| 2010-09-21 | Tue | COL | NL | H | N | 151 | W | 3-1 | 9 | box - pbp - pit | W1 | 61-90 | 5 | 15 | 28 | 2:34 | 37,460 | Joe Saunders | Jorge De La Rosa (L) | Joe Saunders | Jorge de la Rosa | Juan Gutierrez | |
| 2010-09-22 | Wed | COL | NL | H | N | 152 | W | 8-4 | 9 | box - pbp - pit | W2 | 62-90 | 5 | 15 | 28 | 3:12 | 29,903 | Rodrigo Lopez | Ubaldo Jimenez (R) | Rodrigo Lopez | Ubaldo Jimenez | Sam Demel | |
| 2010-09-23 | Thu | COL | NL | H | N | 153 | W | 10-9 | 9 | box - pbp - pit | W3 | 62-91 | 5 | 15 | 28 | 3:48 | 30,093 | Ian Kennedy | Jeff Francis (L) | D.J. Carrasco | Jeff Francis | Juan Gutierrez | |
| 2010-09-24 | Fri | LAN | NL | H | N | 154 | L | 1-3 | 9 | box - pbp - pit | L1 | 62-92 | 5 | 15 | 28 | 2:26 | 38,516 | Barry Enright | Clayton Kershaw (L) | Clayton Kershaw | Barry Enright | Kenley Jansen | |
| 2010-09-25 | Sat | LAN | NL | H | N | 155 | W | 5-2 | 9 | box - pbp - pit | W1 | 63-92 | 5 | 15 | 28 | 2:26 | 41,477 | Daniel Hudson | John Ely (R) | Daniel Hudson | John Ely | Juan Gutierrez | |
| 2010-09-26 | Sun | LAN | NL | H | D | 156 | W | 5-4 | 9 | box - pbp - pit | W2 | 64-92 | 5 | 15 | 28 | 2:59 | 37,911 | Joe Saunders | Chad Billingsley (R) | Sam Demel | Jonathan Broxton | Juan Gutierrez | |
| 2010-09-28 | Tue | SFN | NL | A | N | 157 | L | 2-4 | 9 | box - pbp - pit | L1 | 64-93 | 5 | 15 | 28 | 2:45 | 37,449 | Rodrigo Lopez | Jonathan Sanchez (L) | Jonathan Sanchez | Rodrigo Lopez | Brian Wilson | |
| 2010-09-29 | Wed | SFN | NL | A | N | 158 | L | 1-3 | 9 | box - pbp - pit | L2 | 64-94 | 5 | 15 | 28 | 2:34 | 38,228 | Ian Kennedy | Tim Lincecum (R) | Tim Lincecum | Ian Kennedy | Brian Wilson | |
| 2010-09-30 | Thu | SFN | NL | A | D | 159 | L | 1-4 | 9 | box - pbp - pit | L3 | 64-95 | 5 | 15 | 28 | 2:26 | 37,261 | Barry Enright | Madison Bumgarner (L) | Madison Bumgarner | Barry Enright | Ramon Ramirez | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2010-10-01 | Fri | LAN | NL | A | N | 160 | W | 7-5 | 9 | box - pbp - pit | W1 | 65-95 | 5 | 15 | 28 | 2:54 | 36,713 | Zach Kroenke | John Ely (R) | Zach Kroenke | John Ely | Juan Gutierrez | |
| 2010-10-02 | Sat | LAN | NL | A | N | 161 | L | 2-3 | 9 | box - pbp - pit | L1 | 65-96 | 5 | 15 | 28 | 2:36 | 41,918 | Joe Saunders | Chad Billingsley (R) | Chad Billingsley | Joe Saunders | Kenley Jansen | |
| 2010-10-03 | Sun | LAN | NL | A | D | 162 | L | 1-3 | 9 | box - pbp - pit | L2 | 65-97 | 5 | 15 | 28 | 2:46 | 38,007 | Rodrigo Lopez | Ted Lilly (L) | Ted Lilly | Rodrigo Lopez | Hong-Chih Kuo |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 162 | 65 | 97 | .401 | 713 | 836 | -123 |
| Home Games | 81 | 40 | 41 | .494 | 384 | 409 | -25 |
| Away Games | 81 | 25 | 56 | .309 | 329 | 427 | -98 |
| Night Games | 117 | 52 | 65 | .444 | 524 | 590 | -66 |
| Day Games | 45 | 13 | 32 | .289 | 189 | 246 | -57 |
| March/April | 23 | 11 | 12 | .478 | 134 | 138 | -4 |
| May | 29 | 9 | 20 | .310 | 123 | 183 | -60 |
| June | 27 | 11 | 16 | .407 | 105 | 125 | -20 |
| July | 25 | 7 | 18 | .280 | 103 | 144 | -41 |
| August | 29 | 16 | 13 | .552 | 148 | 126 | +22 |
| Sept/Oct | 29 | 11 | 18 | .379 | 100 | 120 | -20 |
| 1-Run Games | 42 | 19 | 23 | .452 | 151 | 155 | -4 |
| Close Games (1-2-3 Runs) | 102 | 43 | 59 | .422 | 396 | 427 | -31 |
| Blowouts (7+ runs) | 23 | 11 | 12 | .478 | 149 | 172 | -23 |
| Extra Innings | 13 | 5 | 8 | .385 | 55 | 56 | -1 |
| Shutouts | 14 | 3 | 11 | .214 | 8 | 41 | -33 |
| vs LHSP | 50 | 18 | 32 | .360 | 219 | 291 | -72 |
| vs RHSP | 112 | 47 | 65 | .420 | 494 | 545 | -51 |
| vs Division | 72 | 27 | 45 | .375 | 283 | 374 | -91 |
| vs League | 147 | 59 | 88 | .401 | 647 | 753 | -106 |
| InterLeague | 15 | 6 | 9 | .400 | 66 | 83 | -17 |
