| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-04-07 | Fri | MIL | AL | A | D | 1 | L | 3-11 | 9 | box - pbp | L1 | 0-1 | 3 | 10 | 18 | 2:18 | 47,824 | Mike Flanagan | Jerry Augustine (L) | Jerry Augustine | Mike Flanagan | None | |
| 1978-04-08 | Sat | MIL | AL | A | D | 2 | L | 3-16 | 9 | box - pbp | L2 | 0-2 | 5 | 14 | 25 | 2:54 | 6,470 | Dennis Martinez | Moose Haas (R) | Moose Haas | Dennis Martinez | None | |
| 1978-04-09 | Sun | MIL | AL | A | D | 3 | L | 5-13 | 9 | box - pbp | L3 | 0-3 | 7 | 14 | 25 | 2:53 | 18,514 | Scott McGregor | Lary Sorensen (R) | Lary Sorensen | Scott McGregor | None | |
| 1978-04-10 | Mon | KCA | AL | A | N | 4 | L | 2-4 | 9 | box - pbp | L4 | 0-4 | 7 | 14 | 26 | 2:19 | 38,194 | Nelson Briles | Paul Splittorff (L) | Paul Splittorff | Nelson Briles | Al Hrabosky | |
| 1978-04-12 | Wed | KCA | AL | A | D | 5 | L | 2-5 | 9 | box - pbp | L5 | 0-5 | 7 | 14 | 26 | 2:11 | 17,449 | Mike Flanagan | Dennis Leonard (R) | Dennis Leonard | Mike Flanagan | Steve Mingori | |
| 1978-04-14 | Fri | MIL | AL | H | D | 6 | W | 6-5 | 9 | box - pbp | W1 | 1-5 | 7 | 14 | 25 | 2:30 | 36,086 | Dennis Martinez | Lary Sorensen (R) | Dennis Martinez | Lary Sorensen | Don Stanhouse | |
| 1978-04-15 | Sat | MIL | AL | H | D | 7 | W | 7-0 | 9 | box - pbp | W2 | 2-5 | 6 | 13 | 23 | 2:07 | 7,527 | Jim Palmer | Jerry Augustine (L) | Jim Palmer | Jerry Augustine | None | |
| 1978-04-16 | Sun | MIL | AL | H | D | 8 | W | 7-5 | 9 | box - pbp | W3 | 3-6 | 5 | 10 | 19 | 2:06 | 0 | Nelson Briles | Moose Haas (R) | Nelson Briles | Moose Haas | Don Stanhouse | |
| 1978-04-16 | Sun | MIL | AL | H | D | 9 | L | 2-9 | 9 | box - pbp | L1 | 3-6 | 5 | 10 | 19 | 2:39 | 14,995 | Scott McGregor | Andy Replogle (R) | Andy Replogle | Scott McGregor | Eduardo Rodriguez | |
| 1978-04-17 | Mon | NYA | AL | A | D | 10 | W | 6-1 | 9 | box - pbp | W1 | 4-6 | 5 | 10 | 19 | 2:40 | 15,674 | Mike Flanagan | Catfish Hunter (R) | Mike Flanagan | Catfish Hunter | None | |
| 1978-04-18 | Tue | NYA | AL | A | D | 11 | L | 3-4 | 9 | box - pbp | L1 | 4-7 | 6 | 11 | 20 | 2:18 | 15,628 | Dennis Martinez | Ron Guidry (L) | Sparky Lyle | Tippy Martinez | None | |
| 1978-04-21 | Fri | KCA | AL | H | N | 12 | W | 2-1 | 9 | box - pbp | W1 | 5-7 | 4 | 9 | 18 | 2:15 | 6,203 | Jim Palmer | Dennis Leonard (R) | Jim Palmer | Dennis Leonard | Don Stanhouse | |
| 1978-04-22 | Sat | KCA | AL | H | N | 13 | L | 3-5 | 9 | box - pbp | L1 | 5-8 | 6 | 10 | 19 | 2:29 | 7,277 | Mike Flanagan | Paul Splittorff (L) | Paul Splittorff | Mike Flanagan | Al Hrabosky | |
| 1978-04-23 | Sun | KCA | AL | H | D | 14 | L | 5-6 | 9 | box - pbp | L2 | 5-9 | 6 | 11 | 20 | 3:22 | 13,833 | Dennis Martinez | Steve Busby (R) | Larry Gura | Tim Stoddard | Marty Pattin | |
| 1978-04-24 | Mon | NYA | AL | H | N | 15 | L | 2-8 | 9 | box - pbp | L3 | 5-10 | 6 | 12 | 21 | 2:43 | 18,053 | Scott McGregor | Ron Guidry (L) | Ron Guidry | Scott McGregor | None | |
| 1978-04-25 | Tue | NYA | AL | H | N | 16 | L | 3-4 | 9 | box - pbp | L4 | 5-11 | 6 | 12 | 22 | 2:19 | 14,159 | Jim Palmer | Jim Beattie (R) | Jim Beattie | Jim Palmer | Sparky Lyle | |
| 1978-04-28 | Fri | CHA | AL | A | N | 17 | W | 6-4 | 9 | box - pbp | W1 | 6-11 | 7 | 12 | 23 | 2:46 | 25,395 | Dennis Martinez | Steve Stone (R) | Dennis Martinez | Pablo Torrealba | Don Stanhouse | |
| 1978-04-29 | Sat | CHA | AL | A | N | 18 | W | 5-2 | 9 | box - pbp | W2 | 7-11 | 6 | 10 | 21 | 2:48 | 22,240 | Jim Palmer | Ken Kravec (L) | Jim Palmer | Ken Kravec | Don Stanhouse | |
| 1978-04-30 | Sun | CHA | AL | A | D | 19 | W | 8-7 | 9 | box - pbp | W3 | 8-11 | 5 | 9 | 19 | 3:04 | 17,786 | Mike Flanagan | Francisco Barrios (R) | Scott McGregor | Pablo Torrealba | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-05-01 | Mon | BOS | AL | A | N | 20 | L | 6-9 | 9 | box - pbp | L1 | 8-12 | 6 | 10 | 20 | 3:21 | 18,710 | Nelson Briles | Mike Torrez (R) | Mike Torrez | Nelson Briles | Bob Stanley | |
| 1978-05-02 | Tue | BOS | AL | A | N | 21 | W | 3-1 | 9 | box - pbp | W1 | 9-12 | 5 | 9 | 18 | 2:43 | 19,930 | Dennis Martinez | Allen Ripley (R) | Dennis Martinez | Allen Ripley | None | |
| 1978-05-03 | Wed | TEX | AL | H | N | 22 | L | 1-2 | 9 | box - pbp | L1 | 9-13 | 6 | 10 | 21 | 2:38 | 6,118 | Jim Palmer | Doyle Alexander (R) | Doyle Alexander | Don Stanhouse | None | |
| 1978-05-05 | Fri | MIN | AL | H | N | 23 | W | 2-1 | 9 | box - pbp | W1 | 10-13 | 6 | 10 | 18 | 1:57 | 3,897 | Mike Flanagan | Geoff Zahn (L) | Mike Flanagan | Geoff Zahn | None | |
| 1978-05-06 | Sat | MIN | AL | H | N | 24 | L | 7-8 | 9 | box - pbp | L1 | 10-14 | 6 | 10 | 18 | 3:13 | 26,870 | Dennis Martinez | Roger Erickson (R) | Greg Thayer | Don Stanhouse | Tom Johnson | |
| 1978-05-07 | Sun | MIN | AL | H | D | 25 | L | 9-15 | 9 | box - pbp | L2 | 10-15 | 6 | 10 | 20 | 3:16 | 8,923 | Jim Palmer | Gary Serum (R) | Mac Scarce | Jim Palmer | None | |
| 1978-05-10 | Wed | BOS | AL | H | N | 26 | W | 3-2 | 9 | box - pbp | W1 | 11-15 | 6 | 10 | 18 | 2:21 | 10,023 | Mike Flanagan | Allen Ripley (R) | Mike Flanagan | Tom Burgmeier | None | |
| 1978-05-11 | Thu | BOS | AL | H | N | 27 | L | 4-5 | 9 | box - pbp | L1 | 11-16 | 6 | 10 | 19 | 3:18 | 14,950 | Dennis Martinez | Bill Lee (L) | Bill Lee | Dennis Martinez | Dick Drago | |
| 1978-05-12 | Fri | TEX | AL | A | N | 28 | L | 3-9 | 9 | box - pbp | L2 | 11-17 | 6 | 10 | 21 | 2:53 | 30,803 | Jim Palmer | Jon Matlack (L) | Jon Matlack | Jim Palmer | None | |
| 1978-05-13 | Sat | TEX | AL | A | N | 29 | W | 5-1 | 9 | box - pbp | W1 | 12-17 | 6 | 10 | 20 | 1:51 | 32,700 | Scott McGregor | Jim Umbarger (L) | Scott McGregor | Jim Umbarger | None | |
| 1978-05-14 | Sun | TEX | AL | A | N | 30 | W | 3-2 | 9 | box - pbp | W2 | 13-17 | 6 | 10 | 18 | 2:40 | 16,440 | Mike Flanagan | Dock Ellis (R) | John Flinn | Dock Ellis | Don Stanhouse | |
| 1978-05-15 | Mon | MIN | AL | A | N | 31 | L | 6-9 | 10 | box - pbp | L1 | 13-18 | 6 | 10 | 19 | 3:28 | 3,847 | Dennis Martinez | Roger Erickson (R) | Mike Marshall | John Flinn | None | |
| 1978-05-16 | Tue | MIN | AL | A | N | 32 | L | 1-8 | 9 | box - pbp | L2 | 13-19 | 6 | 11 | 20 | 2:34 | 4,893 | Jim Palmer | Dave Goltz (R) | Dave Goltz | Jim Palmer | Tom Johnson | |
| 1978-05-18 | Thu | TOR | AL | H | N | 33 | W | 5-3 | 9 | box - pbp | W1 | 14-19 | 6 | 10 | 20 | 2:31 | 4,255 | Mike Flanagan | Jim Clancy (R) | Mike Flanagan | Jim Clancy | None | |
| 1978-05-19 | Fri | CLE | AL | A | N | 34 | L | 5-7 | 9 | box - pbp | L1 | 14-20 | 6 | 10 | 20 | 2:59 | 15,565 | Dennis Martinez | Mike Paxton (R) | Jim Kern | Don Stanhouse | None | |
| 1978-05-20 | Sat | CLE | AL | A | D | 35 | W | 2-1 | 9 | box - pbp | W1 | 15-20 | 6 | 10 | 20 | 2:38 | 11,426 | Jim Palmer | Rick Wise (R) | Jim Palmer | Rick Wise | Don Stanhouse | |
| 1978-05-21 | Sun | CLE | AL | A | D | 36 | W | 3-0 | 9 | box - pbp | W2 | 16-21 | 6 | 10 | 20 | 2:01 | 0 | Scott McGregor | Rick Waits (L) | Scott McGregor | Rick Waits | None | |
| 1978-05-21 | Sun | CLE | AL | A | D | 37 | L | 2-3 | 9 | box - pbp | L1 | 16-21 | 6 | 10 | 20 | 2:35 | 23,206 | Nelson Briles | David Clyde (L) | David Clyde | Nelson Briles | Dennis Kinney | |
| 1978-05-23 | Tue | DET | AL | H | N | 38 | W | 2-0 | 9 | box - pbp | W1 | 17-21 | 6 | 10 | 20 | 1:51 | 4,536 | Mike Flanagan | Jack Billingham (R) | Mike Flanagan | Jack Billingham | None | |
| 1978-05-24 | Wed | DET | AL | H | N | 39 | L | 2-3 | 9 | box - pbp | L1 | 18-22 | 6 | 10 | 20 | 2:29 | 0 | Dennis Martinez | Jim Slaton (R) | John Hiller | Dennis Martinez | None | |
| 1978-05-24 | Wed | DET | AL | H | N | 40 | W | 1-0 | 9 | box - pbp | W1 | 18-22 | 6 | 10 | 20 | 1:57 | 8,196 | Jim Palmer | Bob Sykes (L) | Jim Palmer | Bob Sykes | None | |
| 1978-05-25 | Thu | DET | AL | H | N | 41 | W | 2-1 | 9 | box - pbp | W2 | 19-22 | 5 | 9 | 18 | 2:13 | 5,109 | Scott McGregor | Steve Baker (R) | Scott McGregor | John Hiller | None | |
| 1978-05-26 | Fri | CLE | AL | H | N | 42 | W | 4-3 | 9 | box - pbp | W3 | 20-22 | 5 | 9 | 16 | 2:53 | 29,215 | Nelson Briles | Rick Wise (R) | Tippy Martinez | Rick Wise | None | |
| 1978-05-27 | Sat | CLE | AL | H | D | 43 | L | 2-6 | 9 | box - pbp | L1 | 20-23 | 5 | 9 | 17 | 2:22 | 8,920 | Mike Flanagan | David Clyde (L) | David Clyde | Mike Flanagan | None | |
| 1978-05-28 | Sun | CLE | AL | H | D | 44 | L | 3-4 | 10 | box - pbp | L2 | 21-24 | 5 | 9 | 17 | 2:57 | 0 | Dennis Martinez | Don Hood (L) | Sid Monge | Don Stanhouse | None | |
| 1978-05-28 | Sun | CLE | AL | H | N | 45 | W | 3-0 | 9 | box - pbp | W1 | 21-24 | 5 | 9 | 17 | 2:30 | 18,276 | Jim Palmer | Mike Paxton (R) | Jim Palmer | Mike Paxton | None | |
| 1978-05-29 | Mon | DET | AL | A | N | 46 | W | 6-3 | 9 | box - pbp | W2 | 22-24 | 5 | 9 | 16 | 2:00 | 20,534 | Scott McGregor | Bob Sykes (L) | Scott McGregor | Bob Sykes | None | |
| 1978-05-30 | Tue | DET | AL | A | N | 47 | L | 2-5 | 9 | box - pbp | L1 | 22-25 | 5 | 9 | 16 | 2:25 | 10,530 | Nelson Briles | Steve Baker (R) | Steve Baker | Nelson Briles | John Hiller | |
| 1978-05-31 | Wed | NYA | AL | A | N | 48 | W | 3-2 | 9 | box - pbp | W1 | 23-25 | 5 | 9 | 15 | 2:23 | 21,404 | Mike Flanagan | Ed Figueroa (R) | Mike Flanagan | Ed Figueroa | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-06-01 | Thu | NYA | AL | A | N | 49 | W | 1-0 | 9 | box - pbp | W2 | 24-25 | 5 | 9 | 15 | 2:12 | 19,943 | Jim Palmer | Jim Beattie (R) | Jim Palmer | Jim Beattie | None | |
| 1978-06-02 | Fri | SEA | AL | A | N | 50 | W | 10-9 | 9 | box - pbp | W3 | 25-25 | 4 | 8 | 14 | 3:02 | 4,936 | Dennis Martinez | Jim Colborn (R) | Dennis Martinez | Jim Colborn | Don Stanhouse | |
| 1978-06-03 | Sat | SEA | AL | A | N | 51 | W | 2-1 | 9 | box - pbp | W4 | 26-25 | 4 | 7 | 13 | 2:30 | 15,002 | Scott McGregor | Paul Mitchell (R) | Scott McGregor | Paul Mitchell | Tippy Martinez | |
| 1978-06-04 | Sun | SEA | AL | A | D | 52 | W | 4-1 | 9 | box - pbp | W5 | 27-25 | 4 | 7 | 13 | 2:23 | 6,429 | Mike Flanagan | Dick Pole (R) | Mike Flanagan | Dick Pole | None | |
| 1978-06-05 | Mon | CAL | AL | A | N | 53 | W | 6-2 | 10 | box - pbp | W6 | 28-25 | 4 | 6 | 12 | 3:18 | 13,231 | Jim Palmer | Don Aase (R) | Don Stanhouse | Dave LaRoche | None | |
| 1978-06-06 | Tue | CAL | AL | A | N | 54 | W | 8-6 | 9 | box - pbp | W7 | 29-25 | 4 | 6 | 12 | 3:18 | 15,864 | Dennis Martinez | Nolan Ryan (R) | Dennis Martinez | Nolan Ryan | Don Stanhouse | |
| 1978-06-09 | Fri | OAK | AL | A | N | 55 | W | 5-3 | 9 | box - pbp | W8 | 30-25 | 4 | 5 | 10 | 2:32 | 3,323 | Mike Flanagan | Pete Broberg (R) | Mike Flanagan | Pete Broberg | None | |
| 1978-06-10 | Sat | OAK | AL | A | D | 56 | W | 1-0 | 9 | box - pbp | W9 | 31-25 | 4 | 5 | 9 | 2:12 | 11,422 | Jim Palmer | Steve Renko (R) | Jim Palmer | Steve Renko | None | |
| 1978-06-11 | Sun | OAK | AL | A | D | 57 | W | 3-0 | 9 | box - pbp | W10 | 32-25 | 4 | 4 | 8 | 2:00 | 17,157 | Scott McGregor | Mike Morgan (R) | Scott McGregor | Mike Morgan | None | |
| 1978-06-12 | Mon | SEA | AL | H | N | 58 | W | 5-4 | 9 | box - pbp | W11 | 33-25 | 3 | 3 | 6 | 2:24 | 13,212 | Dennis Martinez | Jim Colborn (R) | Tippy Martinez | Jim Colborn | Don Stanhouse | |
| 1978-06-13 | Tue | SEA | AL | H | N | 59 | W | 3-2 | 11 | box - pbp | W12 | 34-25 | 3 | 3 | 6 | 2:27 | 7,729 | Mike Flanagan | Glenn Abbott (R) | Mike Flanagan | Enrique Romo | None | |
| 1978-06-14 | Wed | CAL | AL | H | N | 60 | W | 5-2 | 9 | box - pbp | W13 | 35-25 | 3 | 3 | 5 | 2:24 | 21,815 | Jim Palmer | Ken Brett (L) | Jim Palmer | Ken Brett | None | |
| 1978-06-15 | Thu | CAL | AL | H | N | 61 | L | 1-5 | 9 | box - pbp | L1 | 35-26 | 3 | 3 | 6 | 2:48 | 15,004 | Scott McGregor | Frank Tanana (L) | Frank Tanana | Scott McGregor | None | |
| 1978-06-16 | Fri | OAK | AL | H | N | 62 | W | 6-0 | 9 | box - pbp | W1 | 36-26 | 3 | 3 | 6 | 2:16 | 31,944 | Dennis Martinez | Rick Langford (R) | Dennis Martinez | Rick Langford | None | |
| 1978-06-17 | Sat | OAK | AL | H | N | 63 | W | 5-4 | 9 | box - pbp | W2 | 37-26 | 3 | 3 | 5 | 2:23 | 24,619 | Mike Flanagan | Mike Morgan (R) | Mike Flanagan | Mike Morgan | Don Stanhouse | |
| 1978-06-18 | Sun | OAK | AL | H | D | 64 | W | 2-1 | 9 | box - pbp | W3 | 38-26 | 2 | 2 | 4 | 2:14 | 17,143 | Jim Palmer | John Henry Johnson (L) | Jim Palmer | John Henry Johnson | Tippy Martinez | |
| 1978-06-20 | Tue | MIL | AL | A | N | 65 | W | 8-5 | 9 | box - pbp | W4 | 39-26 | 2 | 2 | 4 | 2:45 | 22,640 | Scott McGregor | Bill Travers (L) | Scott McGregor | Bill Travers | None | |
| 1978-06-21 | Wed | MIL | AL | A | N | 66 | L | 3-5 | 9 | box - pbp | L1 | 39-27 | 2 | 2 | 4 | 2:05 | 21,732 | Dennis Martinez | Lary Sorensen (R) | Lary Sorensen | Dennis Martinez | Bill Castro | |
| 1978-06-22 | Thu | MIL | AL | A | D | 67 | W | 10-3 | 9 | box - pbp | W1 | 40-27 | 2 | 2 | 4 | 2:20 | 26,586 | Mike Flanagan | Moose Haas (R) | Mike Flanagan | Moose Haas | None | |
| 1978-06-23 | Fri | BOS | AL | A | N | 68 | L | 2-5 | 9 | box - pbp | L1 | 40-28 | 2 | 2 | 4 | 2:19 | 34,582 | Jim Palmer | Bill Lee (L) | Bill Lee | Jim Palmer | None | |
| 1978-06-24 | Sat | BOS | AL | A | D | 69 | L | 3-8 | 9 | box - pbp | L2 | 40-29 | 2 | 2 | 4 | 2:42 | 32,213 | Scott McGregor | Luis Tiant (R) | Luis Tiant | Scott McGregor | None | |
| 1978-06-25 | Sun | BOS | AL | A | D | 70 | L | 1-4 | 9 | box - pbp | L3 | 40-30 | 3 | 3 | 5 | 2:48 | 33,526 | Dennis Martinez | Mike Torrez (R) | Mike Torrez | Dennis Martinez | None | |
| 1978-06-26 | Mon | TOR | AL | A | N | 71 | L | 10-24 | 9 | box - pbp | L4 | 40-31 | 3 | 3 | 5 | 2:58 | 16,184 | Mike Flanagan | Tom Underwood (L) | Tom Underwood | Mike Flanagan | None | |
| 1978-06-27 | Tue | TOR | AL | A | N | 72 | L | 2-6 | 9 | box - pbp | L5 | 40-33 | 4 | 5 | 9 | 2:22 | 0 | Jim Palmer | Dave Lemanczyk (R) | Dave Lemanczyk | Jim Palmer | Victor Cruz | |
| 1978-06-27 | Tue | TOR | AL | A | N | 73 | L | 8-9 | 9 | box - pbp | L6 | 40-33 | 4 | 5 | 9 | 3:15 | 38,563 | Nelson Briles | Jesse Jefferson (R) | Victor Cruz | Don Stanhouse | None | |
| 1978-06-28 | Wed | TOR | AL | A | N | 74 | L | 2-3 | 9 | box - pbp | L7 | 40-34 | 4 | 5 | 9 | 2:09 | 28,392 | Scott McGregor | Jim Clancy (R) | Jim Clancy | Scott McGregor | Tom Murphy | |
| 1978-06-29 | Thu | BOS | AL | H | N | 75 | L | 3-4 | 9 | box - pbp | L8 | 40-35 | 4 | 5 | 9 | 2:57 | 28,899 | Dennis Martinez | Bill Lee (L) | Allen Ripley | Dennis Martinez | None | |
| 1978-06-30 | Fri | BOS | AL | H | N | 76 | W | 3-2 | 11 | box - pbp | W1 | 41-35 | 4 | 4 | 8 | 3:01 | 33,034 | Mike Flanagan | Luis Tiant (R) | Don Stanhouse | Luis Tiant | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-07-01 | Sat | BOS | AL | H | N | 77 | W | 3-2 | 11 | box - pbp | W2 | 42-35 | 4 | 4 | 8 | 3:24 | 38,542 | Jim Palmer | Mike Torrez (R) | Nelson Briles | Mike Torrez | None | |
| 1978-07-03 | Mon | CLE | AL | A | N | 78 | L | 0-9 | 9 | box - pbp | L1 | 42-36 | 4 | 4 | 8 | 2:23 | 9,302 | Scott McGregor | Mike Paxton (R) | Mike Paxton | Scott McGregor | None | |
| 1978-07-04 | Tue | CLE | AL | A | N | 79 | W | 6-4 | 9 | box - pbp | W1 | 43-36 | 4 | 4 | 8 | 3:01 | 36,300 | Dennis Martinez | David Clyde (L) | Dennis Martinez | David Clyde | Don Stanhouse | |
| 1978-07-05 | Wed | TOR | AL | H | N | 80 | W | 3-1 | 9 | box - pbp | W2 | 45-36 | 4 | 4 | 8 | 1:53 | 0 | Mike Flanagan | Jerry Garvin (L) | Mike Flanagan | Jerry Garvin | None | |
| 1978-07-05 | Wed | TOR | AL | H | N | 81 | W | 8-6 | 9 | box - pbp | W3 | 45-36 | 4 | 4 | 8 | 2:57 | 9,886 | Nelson Briles | Tom Underwood (L) | Joe Kerrigan | Tom Murphy | None | |
| 1978-07-06 | Thu | TOR | AL | H | N | 82 | L | 0-2 | 9 | box - pbp | L1 | 45-37 | 4 | 4 | 8 | 2:28 | 14,926 | Jim Palmer | Dave Lemanczyk (R) | Dave Lemanczyk | Jim Palmer | Mike Willis | |
| 1978-07-07 | Fri | KCA | AL | A | N | 83 | L | 1-3 | 9 | box - pbp | L2 | 45-38 | 4 | 4 | 8 | 2:08 | 23,314 | Scott McGregor | Paul Splittorff (L) | Paul Splittorff | Scott McGregor | None | |
| 1978-07-08 | Sat | KCA | AL | A | N | 84 | L | 3-11 | 9 | box - pbp | L3 | 45-39 | 4 | 5 | 9 | 2:58 | 34,587 | Dennis Martinez | Rich Gale (R) | Rich Gale | Dennis Martinez | None | |
| 1978-07-09 | Sun | KCA | AL | A | D | 85 | L | 4-10 | 9 | box - pbp | L4 | 45-40 | 4 | 5 | 9 | 2:16 | 24,662 | Mike Flanagan | Dennis Leonard (R) | Dennis Leonard | Mike Flanagan | None | |
| 1978-07-13 | Thu | MIN | AL | H | N | 86 | W | 8-6 | 9 | box - pbp | W1 | 46-40 | 4 | 5 | 9 | 2:44 | 8,119 | Mike Flanagan | Dave Goltz (R) | Mike Flanagan | Dave Goltz | Tippy Martinez | |
| 1978-07-14 | Fri | MIN | AL | H | N | 87 | W | 5-1 | 9 | box - pbp | W2 | 47-40 | 4 | 5 | 9 | 2:33 | 24,195 | Scott McGregor | Geoff Zahn (L) | Scott McGregor | Geoff Zahn | None | |
| 1978-07-15 | Sat | TEX | AL | H | N | 88 | W | 8-7 | 9 | box - pbp | W3 | 48-41 | 4 | 5 | 9 | 3:07 | 0 | Dennis Martinez | Doyle Alexander (R) | Tippy Martinez | Len Barker | None | |
| 1978-07-15 | Sat | TEX | AL | H | N | 89 | L | 1-11 | 9 | box - pbp | L1 | 48-41 | 4 | 5 | 9 | 2:55 | 22,353 | Jim Palmer | Doc Medich (R) | Doc Medich | Jim Palmer | None | |
| 1978-07-16 | Sun | TEX | AL | H | D | 90 | W | 2-1 | 12 | box - pbp | W1 | 49-41 | 3 | 3 | 8 | 3:19 | 11,839 | Joe Kerrigan | Jon Matlack (L) | Don Stanhouse | Reggie Cleveland | None | |
| 1978-07-17 | Mon | TEX | AL | H | N | 91 | L | 0-2 | 11 | box - pbp | L1 | 49-42 | 3 | 4 | 9 | 2:34 | 11,676 | Mike Flanagan | Steve Comer (R) | Reggie Cleveland | Mike Flanagan | None | |
| 1978-07-18 | Tue | TEX | AL | H | N | 92 | W | 5-1 | 9 | box - pbp | W1 | 50-42 | 3 | 3 | 7 | 2:30 | 10,832 | Scott McGregor | Dock Ellis (R) | Scott McGregor | Dock Ellis | None | |
| 1978-07-19 | Wed | CHA | AL | A | N | 93 | W | 10-3 | 9 | box - pbp | W2 | 51-42 | 3 | 3 | 7 | 2:39 | 18,682 | Jim Palmer | Ken Kravec (L) | Jim Palmer | Ken Kravec | None | |
| 1978-07-21 | Fri | MIN | AL | A | N | 94 | W | 5-4 | 10 | box - pbp | W3 | 52-42 | 3 | 4 | 8 | 2:52 | 14,702 | Mike Flanagan | Roger Erickson (R) | Don Stanhouse | Mike Marshall | None | |
| 1978-07-22 | Sat | MIN | AL | A | D | 95 | L | 4-5 | 9 | box - pbp | L1 | 52-43 | 4 | 5 | 9 | 2:32 | 10,063 | Scott McGregor | Dave Goltz (R) | Dave Goltz | Scott McGregor | None | |
| 1978-07-23 | Sun | MIN | AL | A | D | 96 | W | 8-5 | 9 | box - pbp | W1 | 53-43 | 4 | 5 | 9 | 2:47 | 30,896 | Jim Palmer | Gary Serum (R) | Jim Palmer | Gary Serum | Don Stanhouse | |
| 1978-07-24 | Mon | TEX | AL | A | N | 97 | W | 10-6 | 9 | box - pbp | W2 | 54-43 | 3 | 4 | 8 | 3:04 | 11,732 | Dennis Martinez | Fergie Jenkins (R) | Don Stanhouse | Fergie Jenkins | Scott McGregor | |
| 1978-07-25 | Tue | TEX | AL | A | N | 98 | W | 7-6 | 9 | box - pbp | W3 | 55-43 | 3 | 4 | 8 | 2:46 | 12,686 | Joe Kerrigan | Doyle Alexander (R) | Joe Kerrigan | Doyle Alexander | Tippy Martinez | |
| 1978-07-26 | Wed | DET | AL | A | N | 99 | L | 6-9 | 9 | box - pbp | L1 | 55-44 | 4 | 5 | 9 | 2:36 | 18,056 | Mike Flanagan | Jack Billingham (R) | Jack Billingham | Mike Flanagan | Bob Sykes | |
| 1978-07-27 | Thu | DET | AL | A | N | 100 | W | 7-3 | 9 | box - pbp | W1 | 56-44 | 3 | 4 | 7 | 2:21 | 22,856 | Scott McGregor | Jim Slaton (R) | Scott McGregor | Jim Slaton | None | |
| 1978-07-28 | Fri | CAL | AL | H | N | 101 | W | 5-4 | 9 | box - pbp | W2 | 57-44 | 3 | 4 | 7 | 2:28 | 14,407 | Jim Palmer | Don Aase (R) | Jim Palmer | Don Aase | Don Stanhouse | |
| 1978-07-29 | Sat | CAL | AL | H | N | 102 | L | 1-2 | 9 | box - pbp | L1 | 57-45 | 3 | 4 | 7 | 2:23 | 23,504 | Dennis Martinez | Paul Hartzell (R) | Paul Hartzell | Dennis Martinez | None | |
| 1978-07-30 | Sun | CAL | AL | H | D | 103 | L | 2-4 | 9 | box - pbp | L2 | 57-46 | 3 | 4 | 8 | 3:11 | 15,350 | Mike Flanagan | Dave Frost (R) | Dave Frost | Mike Flanagan | Dave LaRoche | |
| 1978-07-31 | Mon | MIL | AL | H | N | 104 | W | 6-5 | 10 | box - pbp | W1 | 58-46 | 3 | 4 | 8 | 2:56 | 10,514 | Scott McGregor | Bill Travers (L) | Joe Kerrigan | Bill Castro | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-08-02 | Wed | MIL | AL | H | N | 105 | L | 3-5 | 9 | box - pbp | L1 | 58-47 | 4 | 5 | 8 | 2:50 | 10,663 | Jim Palmer | Mike Caldwell (L) | Mike Caldwell | Jim Palmer | Lary Sorensen | |
| 1978-08-03 | Thu | MIL | AL | H | N | 106 | W | 3-2 | 10 | box - pbp | W1 | 59-47 | 3 | 4 | 7 | 2:33 | 9,654 | Dennis Martinez | Jerry Augustine (L) | Dennis Martinez | Jerry Augustine | None | |
| 1978-08-04 | Fri | NYA | AL | A | N | 107 | W | 2-1 | 9 | box - pbp | W2 | 60-47 | 3 | 3 | 5 | 2:19 | 28,189 | Mike Flanagan | Ron Guidry (L) | Mike Flanagan | Ron Guidry | Don Stanhouse | |
| 1978-08-05 | Sat | NYA | AL | A | N | 108 | L | 2-3 | 9 | box - pbp | L1 | 60-48 | 3 | 4 | 7 | 2:26 | 26,727 | Scott McGregor | Ed Figueroa (R) | Sparky Lyle | Tippy Martinez | None | |
| 1978-08-06 | Sun | NYA | AL | A | D | 109 | L | 0-3 | 9 | box - pbp | L2 | 60-49 | 4 | 5 | 9 | 2:03 | 40,765 | Jim Palmer | Catfish Hunter (R) | Catfish Hunter | Jim Palmer | None | |
| 1978-08-07 | Mon | TOR | AL | A | D | 110 | L | 1-2 | 9 | box - pbp | L3 | 60-50 | 5 | 6 | 10 | 2:04 | 19,184 | Dennis Martinez | Jim Clancy (R) | Jim Clancy | Dennis Martinez | None | |
| 1978-08-08 | Tue | TOR | AL | A | N | 111 | L | 3-5 | 9 | box - pbp | L4 | 60-51 | 5 | 6 | 10 | 2:18 | 19,052 | Mike Flanagan | Tom Underwood (L) | Tom Underwood | Mike Flanagan | Victor Cruz | |
| 1978-08-09 | Wed | KCA | AL | H | N | 112 | L | 0-2 | 9 | box - pbp | L5 | 60-52 | 5 | 7 | 11 | 2:11 | 12,859 | Scott McGregor | Larry Gura (L) | Larry Gura | Scott McGregor | None | |
| 1978-08-10 | Thu | KCA | AL | H | N | 113 | W | 3-2 | 9 | box - pbp | W1 | 61-52 | 5 | 7 | 11 | 2:28 | 9,221 | Jim Palmer | Doug Bird (R) | Jim Palmer | Doug Bird | Don Stanhouse | |
| 1978-08-11 | Fri | NYA | AL | H | N | 114 | L | 1-2 | 6 | box - pbp | L1 | 61-53 | 5 | 7 | 11 | 2:27 | 29,539 | Dennis Martinez | Catfish Hunter (R) | Catfish Hunter | Dennis Martinez | None | |
| 1978-08-12 | Sat | NYA | AL | H | N | 115 | W | 6-4 | 9 | box - pbp | W1 | 62-53 | 5 | 7 | 11 | 2:53 | 32,153 | Mike Flanagan | Jim Beattie (R) | Mike Flanagan | Jim Beattie | Don Stanhouse | |
| 1978-08-13 | Sun | NYA | AL | H | D | 116 | W | 3-0 | 6 | box - pbp | W2 | 63-53 | 5 | 6 | 10 | 2:03 | 31,591 | Scott McGregor | Ed Figueroa (R) | Scott McGregor | Ed Figueroa | None | |
| 1978-08-14 | Mon | NYA | AL | H | N | 117 | L | 1-4 | 9 | box - pbp | L1 | 63-54 | 5 | 7 | 11 | 2:42 | 30,397 | Jim Palmer | Dick Tidrow (R) | Rich Gossage | Jim Palmer | None | |
| 1978-08-15 | Tue | SEA | AL | A | N | 118 | W | 7-4 | 9 | box - pbp | W1 | 64-54 | 5 | 7 | 11 | 2:53 | 7,999 | Dennis Martinez | Glenn Abbott (R) | Dennis Martinez | Glenn Abbott | Don Stanhouse | |
| 1978-08-16 | Wed | SEA | AL | A | N | 119 | L | 5-7 | 9 | box - pbp | L1 | 64-55 | 5 | 7 | 11 | 2:47 | 6,619 | Mike Flanagan | Byron McLaughlin (R) | Byron McLaughlin | Mike Flanagan | Jim Todd | |
| 1978-08-18 | Fri | CAL | AL | A | N | 120 | L | 2-3 | 9 | box - pbp | L2 | 64-56 | 5 | 7 | 11 | 2:25 | 19,488 | Scott McGregor | Chris Knapp (R) | Chris Knapp | Scott McGregor | None | |
| 1978-08-19 | Sat | CAL | AL | A | N | 121 | L | 3-4 | 9 | box - pbp | L3 | 64-57 | 5 | 7 | 11 | 2:10 | 38,870 | Jim Palmer | Paul Hartzell (R) | Paul Hartzell | Jim Palmer | None | |
| 1978-08-20 | Sun | CAL | AL | A | D | 122 | L | 0-1 | 14 | box - pbp | L4 | 64-58 | 5 | 7 | 11 | 3:43 | 20,773 | Dennis Martinez | Nolan Ryan (R) | Tom Griffin | Don Stanhouse | None | |
| 1978-08-21 | Mon | OAK | AL | A | N | 123 | W | 3-2 | 9 | box - pbp | W1 | 65-58 | 5 | 7 | 11 | 2:16 | 9,786 | Mike Flanagan | Rick Langford (R) | Mike Flanagan | Rick Langford | None | |
| 1978-08-22 | Tue | OAK | AL | A | N | 124 | W | 6-4 | 10 | box - pbp | W2 | 66-58 | 5 | 7 | 11 | 3:29 | 1,930 | Scott McGregor | Pete Broberg (R) | Don Stanhouse | Bob Lacey | Joe Kerrigan | |
| 1978-08-23 | Wed | OAK | AL | A | N | 125 | W | 11-0 | 9 | box - pbp | W3 | 67-58 | 5 | 7 | 11 | 2:24 | 2,497 | Jim Palmer | Steve Renko (R) | Jim Palmer | Steve Renko | None | |
| 1978-08-25 | Fri | SEA | AL | H | N | 126 | W | 5-0 | 9 | box - pbp | W4 | 68-58 | 5 | 6 | 10 | 2:32 | 10,538 | Dennis Martinez | Paul Mitchell (R) | Dennis Martinez | Paul Mitchell | None | |
| 1978-08-26 | Sat | SEA | AL | H | N | 127 | W | 9-2 | 9 | box - pbp | W5 | 69-58 | 5 | 5 | 8 | 2:15 | 16,484 | Mike Flanagan | Jim Colborn (R) | Mike Flanagan | Jim Colborn | Joe Kerrigan | |
| 1978-08-27 | Sun | SEA | AL | H | D | 128 | W | 4-3 | 9 | box - pbp | W6 | 70-58 | 5 | 5 | 7 | 2:31 | 7,260 | Scott McGregor | Rick Honeycutt (L) | Nelson Briles | Enrique Romo | None | |
| 1978-08-28 | Mon | OAK | AL | H | N | 129 | W | 7-3 | 9 | box - pbp | W7 | 71-58 | 5 | 5 | 7 | 2:35 | 6,000 | Jim Palmer | Steve Renko (R) | Jim Palmer | Bob Lacey | None | |
| 1978-08-29 | Tue | OAK | AL | H | N | 130 | W | 6-2 | 9 | box - pbp | W8 | 72-58 | 5 | 5 | 7 | 2:32 | 4,995 | Dennis Martinez | Mike Norris (R) | Dennis Martinez | Mike Norris | None | |
| 1978-08-30 | Wed | NYA | AL | H | N | 131 | L | 4-5 | 9 | box - pbp | L1 | 72-59 | 5 | 5 | 7 | 2:38 | 20,501 | Mike Flanagan | Ron Guidry (L) | Ron Guidry | Tippy Martinez | Rich Gossage | |
| 1978-08-31 | Thu | NYA | AL | H | N | 132 | L | 2-6 | 9 | box - pbp | L2 | 72-60 | 5 | 5 | 8 | 2:37 | 15,579 | Scott McGregor | Dick Tidrow (R) | Dick Tidrow | Scott McGregor | Sparky Lyle | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-09-01 | Fri | CHA | AL | H | N | 133 | W | 3-0 | 9 | box - pbp | W1 | 74-60 | 5 | 5 | 7 | 2:16 | 0 | Jim Palmer | Steve Stone (R) | Jim Palmer | Steve Stone | Don Stanhouse | |
| 1978-09-01 | Fri | CHA | AL | H | N | 134 | W | 9-3 | 9 | box - pbp | W2 | 74-60 | 5 | 5 | 7 | 2:23 | 6,614 | Sammy Stewart | Ross Baumgarten (L) | Sammy Stewart | Ross Baumgarten | Joe Kerrigan | |
| 1978-09-02 | Sat | CHA | AL | H | N | 135 | W | 9-4 | 9 | box - pbp | W3 | 76-60 | 4 | 4 | 6 | 2:23 | 0 | Dennis Martinez | Ken Kravec (L) | Dennis Martinez | Ken Kravec | None | |
| 1978-09-02 | Sat | CHA | AL | H | N | 136 | W | 1-0 | 9 | box - pbp | W4 | 76-60 | 4 | 4 | 6 | 2:09 | 10,696 | Dave Ford | Jack Kucek (R) | Dave Ford | Jack Kucek | Tippy Martinez | |
| 1978-09-03 | Sun | CHA | AL | H | D | 137 | L | 2-4 | 9 | box - pbp | L1 | 76-61 | 4 | 4 | 6 | 2:40 | 7,101 | Mike Flanagan | Rich Wortham (L) | Lerrin LaGrow | Mike Flanagan | None | |
| 1978-09-04 | Mon | BOS | AL | H | N | 138 | W | 5-3 | 9 | box - pbp | W1 | 77-61 | 4 | 4 | 6 | 2:37 | 0 | Scott McGregor | Dennis Eckersley (R) | Scott McGregor | Dennis Eckersley | Don Stanhouse | |
| 1978-09-05 | Tue | BOS | AL | H | N | 139 | W | 4-1 | 9 | box - pbp | W2 | 78-61 | 4 | 4 | 6 | 2:58 | 15,644 | Jim Palmer | Bobby Sprowl (L) | Jim Palmer | Bobby Sprowl | Don Stanhouse | |
| 1978-09-06 | Wed | BOS | AL | H | N | 140 | L | 0-2 | 9 | box - pbp | L1 | 78-62 | 4 | 4 | 6 | 2:20 | 11,251 | Dennis Martinez | Luis Tiant (R) | Luis Tiant | Dennis Martinez | None | |
| 1978-09-08 | Fri | TOR | AL | A | N | 141 | W | 5-4 | 9 | box - pbp | W1 | 79-62 | 4 | 4 | 6 | 2:24 | 14,155 | Mike Flanagan | Tom Underwood (L) | Nelson Briles | Tom Underwood | Don Stanhouse | |
| 1978-09-09 | Sat | TOR | AL | A | N | 142 | W | 4-0 | 9 | box - pbp | W2 | 80-62 | 4 | 4 | 6 | 2:32 | 29,255 | Scott McGregor | Balor Moore (L) | Scott McGregor | Balor Moore | None | |
| 1978-09-11 | Mon | BOS | AL | A | N | 143 | L | 4-5 | 9 | box - pbp | L1 | 80-63 | 4 | 4 | 6 | 2:44 | 28,575 | Jim Palmer | Luis Tiant (R) | Bob Stanley | Joe Kerrigan | None | |
| 1978-09-12 | Tue | BOS | AL | A | N | 144 | W | 3-2 | 9 | box - pbp | W1 | 81-63 | 4 | 4 | 5 | 2:36 | 28,924 | Dennis Martinez | Mike Torrez (R) | Dennis Martinez | Mike Torrez | None | |
| 1978-09-13 | Wed | MIL | AL | A | N | 145 | L | 5-7 | 9 | box - pbp | L1 | 81-64 | 4 | 4 | 5 | 2:46 | 8,863 | Mike Flanagan | Andy Replogle (R) | Andy Replogle | Mike Flanagan | Ed Farmer | |
| 1978-09-14 | Thu | MIL | AL | A | N | 146 | L | 3-4 | 9 | box - pbp | L2 | 81-65 | 4 | 5 | 6 | 2:21 | 12,587 | Scott McGregor | Mike Caldwell (L) | Mike Caldwell | Scott McGregor | None | |
| 1978-09-15 | Fri | TOR | AL | H | N | 147 | W | 8-3 | 9 | box - pbp | W1 | 82-65 | 4 | 5 | 6 | 2:50 | 4,000 | Jim Palmer | Jim Clancy (R) | Jim Palmer | Victor Cruz | None | |
| 1978-09-16 | Sat | TOR | AL | H | N | 148 | W | 11-1 | 9 | box - pbp | W2 | 83-65 | 4 | 4 | 5 | 2:42 | 10,263 | Dennis Martinez | Jesse Jefferson (R) | Dennis Martinez | Jesse Jefferson | None | |
| 1978-09-17 | Sun | TOR | AL | H | D | 149 | W | 5-0 | 9 | box - pbp | W3 | 84-65 | 4 | 4 | 5 | 2:10 | 4,436 | Mike Flanagan | Don Kirkwood (R) | Mike Flanagan | Don Kirkwood | None | |
| 1978-09-18 | Mon | CLE | AL | A | N | 150 | W | 10-3 | 9 | box - pbp | W4 | 85-65 | 3 | 3 | 4 | 2:42 | 2,873 | Scott McGregor | David Clyde (L) | Scott McGregor | David Clyde | None | |
| 1978-09-19 | Tue | CLE | AL | A | N | 151 | L | 1-2 | 9 | box - pbp | L1 | 85-66 | 4 | 5 | 6 | 2:28 | 3,148 | Jim Palmer | Mike Paxton (R) | Mike Paxton | Don Stanhouse | None | |
| 1978-09-22 | Fri | DET | AL | H | N | 152 | L | 5-7 | 10 | box - pbp | L2 | 85-67 | 4 | 5 | 6 | 2:53 | 5,444 | Mike Flanagan | Kip Young (R) | John Hiller | Mike Flanagan | None | |
| 1978-09-23 | Sat | DET | AL | H | N | 153 | L | 3-4 | 9 | box - pbp | L3 | 86-68 | 4 | 5 | 6 | 2:49 | 0 | Dennis Martinez | Jack Billingham (R) | John Hiller | Don Stanhouse | None | |
| 1978-09-23 | Sat | DET | AL | H | N | 154 | W | 6-1 | 9 | box - pbp | W1 | 86-68 | 4 | 5 | 6 | 2:14 | 13,036 | Jim Palmer | Steve Baker (R) | Jim Palmer | Steve Baker | None | |
| 1978-09-24 | Sun | DET | AL | H | D | 155 | L | 2-4 | 9 | box - pbp | L1 | 86-69 | 4 | 5 | 7 | 2:20 | 9,081 | Scott McGregor | Jim Slaton (R) | Jim Slaton | Don Stanhouse | None | |
| 1978-09-26 | Tue | CLE | AL | H | N | 156 | W | 3-1 | 9 | box - pbp | W1 | 87-69 | 4 | 5 | 7 | 2:18 | 3,662 | Mike Flanagan | Paul Reuschel (R) | Mike Flanagan | Paul Reuschel | Don Stanhouse | |
| 1978-09-27 | Wed | CLE | AL | H | N | 157 | W | 3-1 | 9 | box - pbp | W2 | 88-69 | 4 | 5 | 7 | 2:35 | 2,987 | Dennis Martinez | Rick Waits (L) | Dennis Martinez | Rick Waits | None | |
| 1978-09-28 | Thu | CLE | AL | H | N | 158 | W | 3-2 | 9 | box - pbp | W3 | 89-69 | 4 | 5 | 7 | 1:53 | 5,143 | Jim Palmer | Don Hood (L) | Jim Palmer | Don Hood | Don Stanhouse | |
| 1978-09-29 | Fri | DET | AL | A | N | 159 | L | 2-3 | 9 | box - pbp | L1 | 89-70 | 4 | 5 | 7 | 2:03 | 12,348 | Sammy Stewart | Jim Slaton (R) | Jim Slaton | Sammy Stewart | John Hiller | |
| 1978-09-30 | Sat | DET | AL | A | D | 160 | L | 4-5 | 9 | box - pbp | L2 | 89-71 | 4 | 5 | 8 | 2:24 | 13,919 | Mike Flanagan | Jack Morris (R) | Steve Baker | Mike Flanagan | John Hiller | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 1978-10-01 | Sun | DET | AL | A | D | 161 | W | 4-2 | 9 | box - pbp | W1 | 90-71 | 4 | 5 | 7 | 2:17 | 13,948 | Dennis Martinez | Dave Rozema (R) | Dennis Martinez | Dave Rozema | None |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 161 | 90 | 71 | .559 | 659 | 633 | +26 |
| Home Games | 81 | 51 | 30 | .630 | 316 | 258 | +58 |
| Away Games | 80 | 39 | 41 | .488 | 343 | 375 | -32 |
| Night Games | 121 | 72 | 49 | .595 | 512 | 456 | +56 |
| Day Games | 40 | 18 | 22 | .450 | 147 | 177 | -30 |
| March/April | 19 | 8 | 11 | .421 | 80 | 110 | -30 |
| May | 29 | 15 | 14 | .517 | 100 | 113 | -13 |
| June | 28 | 18 | 10 | .643 | 122 | 118 | +4 |
| July | 28 | 17 | 11 | .607 | 128 | 133 | -5 |
| August | 28 | 14 | 14 | .500 | 102 | 81 | +21 |
| Sept/Oct | 29 | 18 | 11 | .621 | 127 | 78 | +49 |
| 1-Run Games | 63 | 36 | 27 | .571 | 209 | 200 | +9 |
| Close Games (1-2-3 Runs) | 119 | 66 | 53 | .555 | 426 | 405 | +21 |
| Blowouts (7+ runs) | 16 | 7 | 9 | .438 | 96 | 124 | -28 |
| Extra Innings | 14 | 9 | 5 | .643 | 51 | 47 | +4 |
| Shutouts | 23 | 16 | 7 | .696 | 59 | 21 | +38 |
| vs LHSP | 49 | 28 | 21 | .571 | 199 | 185 | +14 |
| vs RHSP | 112 | 62 | 50 | .554 | 460 | 448 | +12 |
| vs Division | 90 | 44 | 46 | .489 | 339 | 362 | -23 |
| vs League | 161 | 90 | 71 | .559 | 659 | 633 | +26 |
| InterLeague | 0 | 0 | 0 | .000 | 0 | 0 | 0 |
