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| | 1 | 1 | Delmon Young | $$ | OF | 17 | 9/14/1985 | 6-2 | 200 | R | R | MLB | 2006-2007 | Camarillo High School (Camarillo,CA) |
| | 2 | 38 | James Houser | $$ | P | 18 | 12/15/1984 | 6-5 | 185 | L | L | AA | | Sarasota High School (Sarasota,FL) |
| | 3 | 68** | Andrew Miller | | P | 18 | 5/21/1985 | 6-6 | 175 | L | L | MLB | 2006-2007 | Buchholz High School (Gainesville,FL) |
| | 4 | 98 | Travis Schlichting | $$ | 3B | 18 | 10/19/1984 | 6-4 | 190 | R | R | A | | Round Rock High School (Round Rock,TX) |
| | 5 | 128 | Jonathan Barratt | | P | 18 | 3/10/1985 | 5-10 | 155 | R | L | AA | | Hillcrest High School (Springfield,MO) |
| | 6 | 158 | Christian Lopez | | C | 18 | 10/10/1984 | 6-1 | 185 | R | R | AAA | | Hialeah High School (Hialeah,FL) |
| | 7 | 188 | Brian Henderson | | P | 21 | 5/19/1982 | 6-0 | 200 | L | L | AA | | University of Houston |
| | 8 | 218 | Matthew Maniscalco | | SS | 22 | 2/18/1981 | 5-10 | 184 | R | R | AAA | | Mississippi State University |
| | 9 | 248** | Billy Buckner | | P | 19 | 8/27/1983 | 6-2 | 195 | R | R | MLB | 2007-2007 | Young Harris College |
| | 10 | 278 | Shaun Cumberland | | OF | 18 | 8/1/1984 | 6-3 | 180 | L | R | AA | | Monsignor Pace High School (Opa Locka,FL) |
| | 11 | 308 | Chad Cooper | | 2B | 22 | 1/31/1981 | 6-1 | 185 | R | R | A- | | Middle Tennessee State University |
| | 12 | 338 | John Jaso | | C | 19 | 9/19/1983 | 6-2 | 200 | L | R | AA | | Southwestern Community College |
| | 13 | 368 | Chad Orvella | | P | 22 | 10/1/1980 | 5-11 | 180 | R | R | MLB | 2005-2007 | North Carolina State University |
| | 14 | 398 | Aaron Gangi | | P | 21 | 12/7/1981 | 6-3 | 190 | L | L | A | | University of Akron |
| | 15 | 428 | Andy Weimer | | P | 22 | 3/20/1981 | 6-2 | 180 | R | R | A | | Le Moyne College |
| | 16 | 458 | Jared Hughes | | P | 17 | 7/4/1985 | 6-7 | 220 | R | R | A | | Santa Margarita Catholic High School (Rancho Santa Margarita,CA) |
| | 17 | 488 | Chris Gustafson | | OF | 18 | 11/2/1984 | 6-1 | 170 | L | R | Rookie | | Kamiak High School (Everett,WA) |
| | 18 | 518 | Jason Cayton | | P | 19 | 3/5/1984 | 6-5 | 200 | L | R | A | | Cal State Northridge |
| | 19 | 548** | Joshua Geer | | P | 20 | 6/2/1983 | 6-2 | 180 | R | R | AAA | | Navarro College |
| | 20 | 578 | Mark Schleicher | | 2B | 21 | 1/1/1982 | 6-1 | 180 | R | R | AA | | Pfeiffer University |
| | 21 | 608** | Casey Hudspeth | | P | 18 | 10/1/1984 | 5-11 | 165 | R | R | A+ | | Sarasota High School (Sarasota,FL) |
| | 22 | 638** | Rod Allen | | OF | 20 | 9/21/1982 | 6-2 | 200 | R | R | A+ | | Arizona State University |
| | 23 | 668 | Ryan McCally | | P | 22 | 2/27/1981 | 6-1 | 195 | R | R | A+ | | Stanford University |
| | 24 | 698** | Chris Shaver | | P | 21 | 8/21/1981 | 6-7 | 235 | L | L | AA | | College of William and Mary |
| | 25 | 728 | Mitch Jones | | OF | 21 | 8/20/1981 | 6-2 | 185 | R | R | A+ | | University of Alabama-Birmingham |
| | 26 | 758 | Joe Little | | P | 21 | 3/10/1982 | 6-1 | 175 | L | L | A+ | | University of Arizona |
| | 27 | 788 | Adam Roos | | 3B | 18 | 5/10/1985 | | | L | R | - | | Hammarskjold High School (Thunder Bay,ON) |
| | 28 | 818 | Andrew Swanson | | P | 18 | 3/11/1985 | | | R | R | - | | Galesburg High School (Galesburg,IL) |
| | 29 | 848 | Fernando Puebla | | SS | 22 | 8/8/1980 | 6-0 | 185 | R | R | A- | | Southern University |
| | 30 | 878 | Adam Ottavino | | P | 17 | 11/22/1985 | 6-4 | | B | R | A+ | | Berkeley Carroll High School (Brooklyn,NY) |
| | 31 | 908 | Thomas Lagreid | | C | 19 | 10/24/1983 | 6-1 | 185 | R | R | A | | Everett Community College (WA) |
| | 32 | 938 | Matt Travis | | P | 22 | 12/26/1980 | 6-0 | 200 | R | L | A- | | Santa Clara University |
| | 33 | 968 | Jordan Olson | | P | 22 | 2/19/1981 | 6-3 | 190 | L | L | A | | USC |
| | 34 | 998 | Travis Fuller | | P | 18 | 12/24/1984 | | | L | L | - | | Hayesville High School (Hayesville,NC) |
| | 35 | 1028 | Gus Jacobson | | P | 18 | 2/21/1985 | | | R | R | College | | Cactus Shadows High School (Cave Creek,AZ) |
| | 36 | 1058 | Wade Leblanc | | P | 18 | 8/7/1984 | 6-2 | 180 | L | L | AA | | Barbe High School (Lake Charles,LA) |
| | 37 | 1088** | Kris Medlen | | SS | 17 | 10/7/1985 | 5-10 | 175 | B | R | AA | | Gahr High School (Cerritos,CA) |
| | 38 | 1118 | Kris Dufner | | SS | 23 | 2/15/1980 | 6-2 | 190 | B | R | A+ | | University of Delaware |
| | 39 | 1148 | Kevin Allen | | OF | 18 | 2/22/1985 | | | R | R | - | | West Henderson High School (West Henderson,NC) |
| | 40 | 1178 | Graham Baxter | | P | 18 | 2/10/1985 | | | R | R | - | | McQueen High School (Reno,NV) |
| | 41 | 1208** | Leon Johnson | | OF | 18 | 6/11/1985 | 6-1 | 185 | L | L | A | | Thatcher High School (Thatcher,AZ) |
| | 42 | 1237 | Travis Beech | | 2B | 22 | 4/22/1981 | 5-11 | 170 | L | R | Rookie | | Austin Peay State University |
| | 43 | 1266** | Grant Theophilus | | P | 18 | 4/22/1985 | | | L | L | College | | Ocean View High School (Huntington Beach,CA) |
| | 44 | 1294 | Josh Kendrick | | 1B | 23 | 6/29/1980 | 6-3 | 230 | R | R | A- | | University of Mobile |
| | 45 | 1322 | Brandon Rousseve | | SS | 18 | 8/4/1984 | 6-1 | 175 | R | R | A | | Meridian College |
| | 46 | 1349 | Josh Bolen | | OF | 23 | 5/5/1980 | 6-3 | 225 | R | R | A- | | University of Louisville |
| | 47 | 1376** | Brad Matthews | | 2B | 20 | 6/8/1983 | 6-0 | 175 | B | R | A- | | Surry Community College |
| | 48 | 1403 | Derrick Shaw | | SS | 18 | 2/26/1985 | | | L | R | - | | Benton High School (Benton,LA) |
| | 49 | 1429 | Lars Davis | | C | 17 | 11/7/1985 | 6-4 | 215 | L | R | A- | | Grande Prairie Composite High School (Grand Prairie,AB) |
| | 50 | 1455 | Brent Speigner | | P | 22 | 4/3/1981 | 6-1 | 200 | R | R | A | | |
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