| East | W | L | Pct | GB |
| Tampa Bay | 97 | 65 | .599 | -- |
| Boston | 95 | 67 | .586 | 2.0 |
| NY Yankees | 89 | 73 | .549 | 8.0 |
| Toronto | 86 | 76 | .531 | 11.0 |
| Baltimore | 68 | 93 | .422 | 28.5 |
| # | Player | Pos | Rk | Age | Drafted | HiLvl | G | AB | R | H | 2B | 3B | HR | RBI | SB | CS | BB | SO | HBP | IBB | SH | SF | DP | AVG | OBP | SLG | OPS | TB | PA | OUT | RC | RC/G | babip |
| 15 | Dustin Pedroia | 2b | 3 | 24 | 2004-2-65 | MLB | 157 | 653 | 118 | 213 | 54 | 2 | 17 | 83 | 20 | 1 | 50 | 52 | 7 | 1 | 7 | 9 | 17 | .326 | .376 | .493 | 869 | 322 | 726 | 474 | 138 | 7.8 | .331 |
| 46 | Jacoby Ellsbury | cf | 35 | 24 | 2005-1-23 | MLB | 145 | 554 | 98 | 155 | 22 | 7 | 9 | 47 | 50 | 11 | 41 | 80 | 7 | 2 | 4 | 3 | 9 | .280 | .336 | .394 | 729 | 218 | 609 | 426 | 83 | 5.2 | .312 |
| 20 | Kevin Youkilis | 3b | 7 | 29 | 2001-8-243 | MLB | 145 | 538 | 91 | 168 | 43 | 4 | 29 | 115 | 3 | 5 | 62 | 108 | 12 | 7 | 0 | 9 | 11 | .312 | .390 | .569 | 958 | 306 | 621 | 395 | 125 | 8.5 | .339 |
| 33 | Jason Varitek | c | 86 | 36 | 1994-1-14 | MLB | 131 | 423 | 37 | 93 | 20 | 0 | 13 | 43 | 0 | 1 | 52 | 122 | 6 | 3 | 0 | 2 | 13 | .220 | .313 | .359 | 672 | 152 | 483 | 346 | 44 | 3.4 | .276 |
| 25 | Mike Lowell | 3b | - | 34 | 1995-20-562 | MLB | 113 | 419 | 58 | 115 | 27 | 0 | 17 | 73 | 2 | 2 | 38 | 61 | 5 | 2 | 0 | 6 | 14 | .274 | .338 | .461 | 798 | 193 | 468 | 326 | 70 | 5.8 | .282 |
| 34 | David Ortiz | dh | 56 | 32 | UDFA: 1992 | MLB | 109 | 416 | 74 | 110 | 30 | 1 | 23 | 89 | 1 | 0 | 70 | 74 | 1 | 12 | 1 | 3 | 11 | .264 | .369 | .507 | 877 | 211 | 491 | 321 | 85 | 7.1 | .270 |
| 7 | J.D. Drew | rf | 73 | 32 | 1998-1-5 | MLB | 109 | 368 | 79 | 103 | 23 | 4 | 19 | 64 | 4 | 1 | 79 | 80 | 4 | 5 | 0 | 5 | 11 | .280 | .408 | .519 | 927 | 191 | 456 | 282 | 84 | 8.1 | .307 |
| 24 | Manny Ramirez | dh | 88 | 36 | 1991-1-13 | MLB | 100 | 365 | 66 | 109 | 22 | 1 | 20 | 68 | 1 | 0 | 52 | 86 | 8 | 8 | 0 | 0 | 12 | .299 | .398 | .529 | 926 | 193 | 425 | 268 | 77 | 7.8 | .344 |
| 10 | Coco Crisp | cf | 54 | 28 | 1999-7-222 | MLB | 118 | 361 | 55 | 102 | 18 | 3 | 7 | 41 | 20 | 7 | 35 | 59 | 1 | 0 | 8 | 4 | 6 | .283 | .344 | .407 | 751 | 147 | 409 | 284 | 56 | 5.3 | .318 |
| 23 | Julio Lugo | ss-3b | - | 32 | 1994-43-1193 | MLB | 82 | 261 | 27 | 70 | 13 | 0 | 1 | 22 | 12 | 4 | 34 | 51 | 4 | 0 | 3 | 5 | 13 | .268 | .355 | .330 | 685 | 86 | 307 | 216 | 31 | 3.9 | .322 |
| 12 | Jed Lowrie | ss | 74 | 24 | 2005-1-45 | MLB | 81 | 260 | 34 | 67 | 25 | 3 | 2 | 46 | 1 | 0 | 35 | 68 | 1 | 0 | 2 | 8 | 8 | .258 | .339 | .400 | 739 | 104 | 306 | 211 | 38 | 4.9 | .328 |
| 22 | Sean Casey | 1b | - | 33 | 1995-2-53 | MLB | 69 | 199 | 14 | 64 | 14 | 0 | 0 | 17 | 1 | 0 | 17 | 25 | 2 | 3 | 0 | 0 | 6 | .322 | .381 | .392 | 773 | 78 | 218 | 141 | 32 | 6.1 | .368 |
| 44 | Jason Bay | lf | - | 29 | 2000-22-645 | MLB | 49 | 184 | 39 | 54 | 12 | 2 | 9 | 37 | 3 | 0 | 22 | 51 | 2 | 2 | 0 | 3 | 4 | .293 | .370 | .527 | 897 | 97 | 211 | 137 | 37 | 7.3 | .354 |
| 13 | Alex Cora | 3b-ss | 87 | 32 | 1996-3-88 | MLB | 75 | 152 | 14 | 41 | 8 | 2 | 0 | 9 | 1 | 1 | 16 | 13 | 9 | 1 | 1 | 1 | 3 | .270 | .371 | .349 | 719 | 53 | 179 | 117 | 24 | 5.5 | .293 |
| 36,30 | Kevin Cash | c | - | 30 | UDFA: 1999 | MLB | 61 | 142 | 11 | 32 | 7 | 0 | 3 | 15 | 0 | 0 | 18 | 50 | 0 | 1 | 0 | 2 | 6 | .225 | .309 | .338 | 647 | 48 | 162 | 118 | 12 | 2.7 | .319 |
| 11 | Mark Kotsay | lf | - | 32 | 1996-1-9 | MLB | 22 | 84 | 6 | 19 | 8 | 1 | 0 | 12 | 0 | 1 | 7 | 11 | 0 | 1 | 0 | 0 | 1 | .226 | .286 | .345 | 631 | 29 | 91 | 67 | 9 | 3.8 | .260 |
| 44 | Brandon Moss | 1b | - | 24 | 2002-8-238 | MLB | 34 | 78 | 7 | 23 | 5 | 1 | 2 | 11 | 1 | 1 | 6 | 25 | 0 | 0 | 0 | 2 | 0 | .295 | .337 | .462 | 799 | 36 | 86 | 58 | 12 | 5.7 | .396 |
| 55 | Jeff Bailey | 1b | - | 29 | 1997-2-64 | MLB | 27 | 50 | 10 | 14 | 1 | 1 | 2 | 6 | 0 | 0 | 9 | 17 | 0 | 1 | 0 | 0 | 2 | .280 | .390 | .460 | 850 | 23 | 59 | 38 | 8 | 5.9 | .387 |
| 54 | Chris Carter | lf-rf | - | 25 | 2004-17-506 | MLB | 9 | 18 | 5 | 6 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | .333 | .400 | .333 | 733 | 6 | 20 | 12 | 2 | 5.2 | .462 |
| 30,60 | Jon Van Every | of | - | 28 | 2000-29-876 | MLB | 11 | 17 | 0 | 4 | 0 | 1 | 0 | 5 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | .235 | .278 | .353 | 631 | 6 | 18 | 13 | 1 | 3.1 | .364 |
| 51 | Gil Velazquez | ss | - | 28 | 1998-14-424 | MLB | 3 | 8 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .125 | .125 | .125 | 250 | 1 | 8 | 7 | 0 | -0.6 | .125 |
| 3 | Joe Thurston | 2b | - | 28 | 1999-4-134 | MLB | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | .000 | .111 | .000 | 111 | 0 | 9 | 8 | -1 | -2.0 | .000 |
| 28 | David Ross | c | - | 31 | 1998-7-216 | MLB | 8 | 8 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 0 | .125 | .125 | .125 | 250 | 1 | 9 | 8 | 0 | -1.5 | .200 |
| 19 | Josh Beckett | p | - | 28 | 1999-1-2 | MLB | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 7 | 7 | - | - | .000 |
| 68 | George Kottaras | c | - | 25 | 2002-20-595 | MLB | 3 | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | .200 | .200 | .400 | 600 | 2 | 5 | 4 | 0 | 2.8 | .333 |
| 31 | Jon Lester | p | - | 24 | 2002-2-57 | MLB | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 5 | 5 | - | - | .000 |
| 63 | Justin Masterson | p | - | 23 | 2006-2-71 | MLB | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 5 | 5 | - | - | .000 |
| 49 | Tim Wakefield | p | - | 41 | 1988-8-200 | MLB | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 3 | 3 | - | - | .000 |
| 40 | Bartolo Colon | p | - | 33 | UDFA: 1993 | MLB | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 2 | 2 | - | - | .000 |
| 18 | Daisuke Matsuzaka | p | - | 27 | UDFA: 2008 | MLB | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 2 | 2 | - | - | .000 |
| 53 | David Aardsma | p | - | 26 | 2003-1-22 | MLB | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 1 | 1 | - | - | .000 |
| 48 | Javier Lopez | p | - | 30 | 1998-4-133 | MLB | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | 0 | 0 | 1 | 1 | - | - | .000 |
| Totals: (32 players) | 162 | 5596 | 845 | 1565 | 353 | 33 | 173 | 807 | 120 | 35 | 646 | 1068 | 70 | 49 | 28 | 62 | 147 | .280 | .358 | .447 | 805 | 2503 | 6402 | 4303 | 960 | 6 | .315 | ||||||
| # | Player | Rk | Age | Drafted | HiLvl | W | L | ERA | G | GS | CG | SH | GF | SV | IP | H | R | ER | HR | BB | SO | WP | Bk | WHIP | H9 | HR9 | BB9 | SO9 | BB/SO | BABIP | GB/FB |
| 31 | Jon Lester | 7 | 24 | 2002-2-57 | MLB | 16 | 6 | 3.21 | 33 | 33 | 2 | 2 | 0 | 0 | 210.1 | 202 | 78 | 75 | 14 | 66 | 152 | 3 | 1 | 1.27 | 8.64 | 0.60 | 2.82 | 6.50 | 0.43 | .302 | 0.99 |
| 49 | Tim Wakefield | 28 | 41 | 1988-8-200 | MLB | 10 | 11 | 4.13 | 30 | 30 | 1 | 0 | 0 | 0 | 181.0 | 154 | 89 | 83 | 25 | 60 | 117 | 12 | 0 | 1.18 | 7.66 | 1.24 | 2.98 | 5.82 | 0.51 | .242 | 0.57 |
| 19 | Josh Beckett | 16 | 28 | 1999-1-2 | MLB | 12 | 10 | 4.03 | 27 | 27 | 1 | 0 | 0 | 0 | 174.1 | 173 | 80 | 78 | 18 | 34 | 172 | 5 | 0 | 1.19 | 8.93 | 0.93 | 1.76 | 8.88 | 0.20 | .320 | 0.74 |
| 18 | Daisuke Matsuzaka | 8 | 27 | UDFA: 2008 | MLB | 18 | 3 | 2.90 | 29 | 29 | 0 | 0 | 0 | 0 | 167.2 | 128 | 58 | 54 | 12 | 94 | 154 | 5 | 0 | 1.32 | 6.87 | 0.64 | 5.05 | 8.27 | 0.61 | .262 | 0.65 |
| 63 | Justin Masterson | - | 23 | 2006-2-71 | MLB | 6 | 5 | 3.16 | 36 | 9 | 0 | 0 | 6 | 0 | 88.1 | 68 | 31 | 31 | 10 | 40 | 68 | 1 | 0 | 1.22 | 6.93 | 1.02 | 4.08 | 6.93 | 0.59 | .245 | 1.22 |
| 61 | Clay Buchholz | - | 23 | 2005-1-42 | MLB | 2 | 9 | 6.75 | 16 | 15 | 1 | 0 | 0 | 0 | 76.0 | 93 | 63 | 57 | 11 | 41 | 72 | 2 | 1 | 1.76 | 11.01 | 1.30 | 4.86 | 8.53 | 0.57 | .360 | 0.97 |
| 17 | Manny Delcarmen | 64 | 26 | 2000-2-62 | MLB | 1 | 2 | 3.27 | 73 | 0 | 0 | 0 | 16 | 2 | 74.1 | 55 | 28 | 27 | 5 | 28 | 72 | 0 | 0 | 1.12 | 6.66 | 0.61 | 3.39 | 8.72 | 0.39 | .262 | 1.13 |
| 58 | Jonathan Papelbon | 32 | 27 | 2003-4-114 | MLB | 5 | 4 | 2.34 | 67 | 0 | 0 | 0 | 62 | 41 | 69.1 | 58 | 24 | 18 | 4 | 8 | 77 | 2 | 0 | 0.95 | 7.53 | 0.52 | 1.04 | 10.00 | 0.10 | .302 | 1.04 |
| 37 | Hideki Okajima | - | 32 | UDFA: 2010 | MLB | 3 | 2 | 2.61 | 64 | 0 | 0 | 0 | 11 | 1 | 62.0 | 49 | 18 | 18 | 6 | 23 | 60 | 2 | 0 | 1.16 | 7.11 | 0.87 | 3.34 | 8.71 | 0.38 | .261 | 0.53 |
| 48 | Javier Lopez | 74 | 30 | 1998-4-133 | MLB | 2 | 0 | 2.43 | 70 | 0 | 0 | 0 | 10 | 0 | 59.1 | 53 | 18 | 16 | 4 | 27 | 38 | 1 | 0 | 1.35 | 8.04 | 0.61 | 4.10 | 5.76 | 0.71 | .282 | 1.54 |
| 50 | Mike Timlin | 86 | 42 | 1987-5-127 | MLB | 4 | 4 | 5.66 | 47 | 0 | 0 | 0 | 26 | 1 | 49.1 | 60 | 32 | 31 | 9 | 20 | 32 | 1 | 0 | 1.62 | 10.95 | 1.64 | 3.65 | 5.84 | 0.63 | .323 | 0.81 |
| 36 | Paul Byrd | 27 | 37 | 1991-4-113 | MLB | 4 | 2 | 4.78 | 8 | 8 | 0 | 0 | 0 | 0 | 49.0 | 58 | 26 | 26 | 8 | 10 | 26 | 0 | 0 | 1.39 | 10.65 | 1.47 | 1.84 | 4.78 | 0.38 | -- | 0.55 |
| 53 | David Aardsma | - | 26 | 2003-1-22 | MLB | 4 | 2 | 5.55 | 47 | 0 | 0 | 0 | 7 | 0 | 48.2 | 49 | 32 | 30 | 4 | 35 | 49 | 3 | 0 | 1.73 | 9.06 | 0.74 | 6.47 | 9.06 | 0.71 | .346 | 0.83 |
| 40 | Bartolo Colon | - | 33 | UDFA: 1993 | MLB | 4 | 2 | 3.92 | 7 | 7 | 0 | 0 | 0 | 0 | 39.0 | 44 | 23 | 17 | 5 | 10 | 27 | 0 | 0 | 1.38 | 10.15 | 1.15 | 2.31 | 6.23 | 0.37 | .315 | 0.74 |
| 56 | Craig Hansen | - | 24 | 2005-1-26 | MLB | 1 | 3 | 5.58 | 32 | 0 | 0 | 0 | 6 | 2 | 30.2 | 29 | 23 | 19 | 2 | 23 | 25 | 3 | 0 | 1.70 | 8.51 | 0.59 | 6.75 | 7.34 | 0.92 | .287 | 1.20 |
| 59 | Chris Smith | - | 27 | 2002-4-118 | MLB | 1 | 0 | 7.85 | 12 | 0 | 0 | 0 | 3 | 0 | 18.1 | 18 | 16 | 16 | 6 | 7 | 13 | 0 | 0 | 1.36 | 8.84 | 2.95 | 3.44 | 6.38 | 0.54 | .240 | 0.38 |
| 51 | Julian Tavarez | - | 35 | UDFA: 1990 | MLB | 0 | 1 | 6.39 | 9 | 0 | 0 | 0 | 2 | 0 | 12.2 | 18 | 12 | 9 | 0 | 9 | 6 | 1 | 0 | 2.13 | 12.79 | 0.00 | 6.39 | 4.26 | 1.50 | -- | 1.53 |
| 62 | David Pauley | - | 25 | 2001-8-240 | MLB | 0 | 1 | 11.68 | 6 | 2 | 0 | 0 | 3 | 0 | 12.1 | 23 | 17 | 16 | 2 | 5 | 11 | 0 | 0 | 2.27 | 16.78 | 1.46 | 3.65 | 8.03 | 0.45 | .447 | 0.79 |
| 43 | Devern Hansack | - | 30 | UDFA: 1999 | MLB | 1 | 0 | 4.05 | 4 | 0 | 0 | 0 | 3 | 0 | 6.2 | 6 | 5 | 3 | 0 | 1 | 5 | 0 | 0 | 1.05 | 8.10 | 0.00 | 1.35 | 6.75 | 0.20 | .316 | 0.82 |
| 30 | Bryan Corey | - | 34 | 1993-12-333 | MLB | 0 | 0 | 10.50 | 7 | 0 | 0 | 0 | 2 | 0 | 6.0 | 11 | 7 | 7 | 1 | 3 | 4 | 0 | 0 | 2.33 | 16.50 | 1.50 | 4.50 | 6.00 | 0.75 | -- | 0.50 |
| 64 | Mike Bowden | - | 21 | 2005-1-47 | MLB | 1 | 0 | 3.60 | 1 | 1 | 0 | 0 | 0 | 0 | 5.0 | 7 | 2 | 2 | 0 | 1 | 3 | 0 | 0 | 1.60 | 12.60 | 0.00 | 1.80 | 5.40 | 0.33 | .389 | 0.20 |
| 51 | Charlie Zink | - | 28 | UDFA: 2002 | MLB | 0 | 0 | 16.62 | 1 | 1 | 0 | 0 | 0 | 0 | 4.1 | 11 | 8 | 8 | 0 | 1 | 1 | 1 | 0 | 2.77 | 22.85 | 0.00 | 2.08 | 2.08 | 1.00 | .478 | 0.64 |
| 39 | Kyle Snyder | - | 30 | 1999-1-7 | MLB | 0 | 0 | 21.60 | 2 | 0 | 0 | 0 | 0 | 0 | 1.2 | 2 | 4 | 4 | 1 | 2 | 1 | 1 | 0 | 2.40 | 10.80 | 5.40 | 10.80 | 5.40 | 2.00 | .250 | 1.00 |
| Totals: (32 players) | 95 | 67 | 4.01 | 162 | 162 | 5 | 2 | 157 | 47 | 1,446 | 1369 | 694 | 645 | 173 | 548 | 1185 | 43 | 2 | 1.53 | 8.52 | 0.91 | 3.41 | 7.37 | 0.46 | .310 | ||||||
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Jason Varitek | C | 131 | 1041 | 903 | 42 | 4 | 7 | .996 | 8.17 | |
| Kevin Cash | C | 57 | 372 | 280 | 26 | 4 | 5 | .987 | 7.40 | |
| David Ross | C | 8 | 25 | 23 | 0 | 0 | 0 | 1.000 | 8.28 | |
| George Kottaras | C | 2 | 8 | 5 | 0 | 0 | 0 | 1.000 | 5.63 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Kevin Youkilis | 1B | 125 | 984 | 923 | 87 | 4 | 92 | .996 | 9.24 | |
| Sean Casey | 1B | 45 | 342 | 331 | 13 | 3 | 25 | .991 | 9.05 | |
| Jeff Bailey | 1B | 12 | 67 | 77 | 3 | 0 | 10 | 1.000 | 10.75 | |
| Mark Kotsay | 1B | 6 | 39 | 35 | 3 | 1 | 7 | .974 | 8.77 | |
| Brandon Moss | 1B | 2 | 13 | 10 | 0 | 0 | 1 | 1.000 | 6.92 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Dustin Pedroia | 2B | 157 | 1376 | 279 | 448 | 6 | 101 | .992 | 4.76 | |
| Alex Cora | 2B | 7 | 35 | 6 | 14 | 0 | 3 | 1.000 | 5.14 | |
| Jed Lowrie | 2B | 3 | 16 | 2 | 4 | 0 | 0 | 1.000 | 3.38 | |
| Gil Velazquez | 2B | 2 | 19 | 5 | 9 | 0 | 2 | 1.000 | 6.63 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Mike Lowell | 3B | 110 | 935 | 80 | 217 | 10 | 20 | .967 | 2.86 | |
| Jed Lowrie | 3B | 45 | 243 | 16 | 59 | 2 | 8 | .974 | 2.78 | |
| Kevin Youkilis | 3B | 36 | 252 | 23 | 70 | 3 | 5 | .969 | 3.32 | |
| Kevin Cash | 3B | 4 | 15 | 1 | 1 | 0 | 0 | 1.000 | 1.20 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Julio Lugo | SS | 81 | 671 | 100 | 176 | 16 | 34 | .945 | 3.70 | |
| Alex Cora | SS | 69 | 386 | 74 | 136 | 6 | 39 | .972 | 4.90 | |
| Jed Lowrie | SS | 49 | 386 | 46 | 109 | 0 | 21 | 1.000 | 3.61 | |
| Gil Velazquez | SS | 1 | 3 | 0 | 1 | 0 | 0 | 1.000 | 3.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Manny Ramirez | LF | 66 | 537 | 99 | 6 | 1 | 2 | .991 | 1.76 | |
| Jacoby Ellsbury | LF | 58 | 346 | 89 | 1 | 0 | 1 | 1.000 | 2.34 | |
| Jason Bay | LF | 49 | 423 | 76 | 5 | 1 | 0 | .988 | 1.72 | |
| Brandon Moss | LF | 11 | 78 | 17 | 0 | 0 | 0 | 1.000 | 1.96 | |
| Jeff Bailey | LF | 5 | 23 | 3 | 0 | 0 | 0 | 1.000 | 1.17 | |
| Joe Thurston | LF | 4 | 19 | 5 | 0 | 0 | 0 | 1.000 | 2.37 | |
| Chris Carter | LF | 3 | 17 | 3 | 0 | 0 | 0 | 1.000 | 1.59 | |
| Julio Lugo | LF | 1 | 1 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Jon Van Every | LF | 1 | 1 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Coco Crisp | CF | 114 | 886 | 234 | 4 | 2 | 1 | .992 | 2.42 | |
| Jacoby Ellsbury | CF | 66 | 546 | 171 | 3 | 0 | 1 | 1.000 | 2.87 | |
| J.D. Drew | CF | 1 | 5 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Jon Van Every | CF | 1 | 8 | 1 | 0 | 0 | 0 | 1.000 | 1.13 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| J.D. Drew | RF | 106 | 886 | 184 | 6 | 4 | 1 | .979 | 1.93 | |
| Jacoby Ellsbury | RF | 36 | 281 | 72 | 0 | 0 | 0 | 1.000 | 2.31 | |
| Mark Kotsay | RF | 19 | 151 | 32 | 0 | 0 | 0 | 1.000 | 1.91 | |
| Brandon Moss | RF | 14 | 86 | 19 | 2 | 0 | 0 | 1.000 | 2.20 | |
| Jon Van Every | RF | 8 | 32 | 15 | 0 | 0 | 0 | 1.000 | 4.22 | |
| Kevin Youkilis | RF | 2 | 8 | 3 | 0 | 0 | 0 | 1.000 | 3.38 | |
| Jeff Bailey | RF | 1 | 1 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| Manny Delcarmen | P | 73 | 74 | 6 | 5 | 0 | 0 | 1.000 | 1.34 | |
| Javier Lopez | P | 70 | 59 | 7 | 10 | 4 | 0 | .810 | 2.59 | |
| Jonathan Papelbon | P | 67 | 69 | 5 | 5 | 3 | 0 | .769 | 1.30 | |
| Hideki Okajima | P | 64 | 62 | 3 | 4 | 0 | 0 | 1.000 | 1.02 | |
| David Aardsma | P | 47 | 48 | 3 | 6 | 0 | 0 | 1.000 | 1.69 | |
| Mike Timlin | P | 47 | 49 | 1 | 9 | 0 | 0 | 1.000 | 1.84 | |
| Justin Masterson | P | 36 | 88 | 3 | 10 | 1 | 2 | .929 | 1.33 | |
| Jon Lester | P | 33 | 210 | 19 | 21 | 2 | 3 | .952 | 1.71 | |
| Craig Hansen | P | 32 | 30 | 0 | 2 | 0 | 0 | 1.000 | 0.60 | |
| Tim Wakefield | P | 30 | 181 | 7 | 15 | 1 | 1 | .957 | 1.09 | |
| Daisuke Matsuzaka | P | 29 | 167 | 16 | 19 | 1 | 2 | .972 | 1.89 | |
| Josh Beckett | P | 27 | 174 | 15 | 18 | 2 | 2 | .943 | 1.71 | |
| Clay Buchholz | P | 16 | 76 | 3 | 6 | 0 | 0 | 1.000 | 1.07 | |
| Chris Smith | P | 12 | 18 | 3 | 2 | 0 | 0 | 1.000 | 2.50 | |
| Julian Tavarez | P | 9 | 12 | 1 | 2 | 0 | 1 | 1.000 | 2.25 | |
| Paul Byrd | P | 8 | 49 | 2 | 9 | 1 | 1 | .917 | 2.02 | |
| Bartolo Colon | P | 7 | 39 | 2 | 4 | 2 | 0 | .750 | 1.38 | |
| Bryan Corey | P | 7 | 6 | 0 | 1 | 0 | 0 | 1.000 | 1.50 | |
| David Pauley | P | 6 | 12 | 0 | 1 | 0 | 0 | 1.000 | 0.75 | |
| Devern Hansack | P | 4 | 6 | 0 | 0 | 1 | 0 | .000 | 0.00 | |
| Kyle Snyder | P | 2 | 1 | 0 | 0 | 0 | 0 | .000 | 0.00 | |
| Mike Bowden | P | 1 | 5 | 1 | 1 | 0 | 1 | 1.000 | 3.60 | |
| Charlie Zink | P | 1 | 4 | 0 | 2 | 0 | 0 | 1.000 | 4.50 | |
| Player | Pos | G | Inn | PO | A | E | DP | Fpct | RF | |
| David Ortiz | DH | 108 | .000 | 0.00 | ||||||
| Manny Ramirez | DH | 31 | .000 | 0.00 | ||||||
| Sean Casey | DH | 7 | .000 | 0.00 | ||||||
| Jeff Bailey | DH | 2 | .000 | 0.00 | ||||||
| J.D. Drew | DH | 2 | .000 | 0.00 | ||||||
| Mike Lowell | DH | 2 | .000 | 0.00 | ||||||
| Chris Carter | DH | 1 | .000 | 0.00 |