| Northern | ||||||||||||||
| Rk | Team | Affiliate | W | L | Pct | Gbl | RF | RA | Manager | Stadium | Attendance | Top Batter | Top Pitcher | Playoffs |
| 1 | Wilmington Blue Rocks | KC | 84 | 55 | .604 | -- | 569 | 486 | Brian Rupp | Daniel S. Frawley Stadium | 288,094 | Johnny Giavotella (5) | Eduardo Paulino (2) | Lost in Semi-Finals |
| 2 | Potomac Nationals | WAN | 79 | 58 | .577 | 4.0 | 674 | 591 | Trent Jewett | G. Richard Pfitzner Stadi | 180,541 | Danny Espinosa (1) | Tommy Milone (4) | |
| 3 | Lynchburg Hillcats ** | PIT | 73 | 66 | .525 | 11.0 | 643 | 621 | P.J. Forbes | Calvin Falwell Field | 164,328 | Jordy Mercer (13) | Matt McSwain (3) | League Champions |
| 4 | Frederick Keys | BAL | 64 | 75 | .460 | 20.0 | 654 | 664 | Richie Hebner | Harry Grove Stadium | 293,438 | Brandon Waring (2) | Zach Britton (5) | |
| Southern | ||||||||||||||
| Rk | Team | Affiliate | W | L | Pct | Gbl | RF | RA | Manager | Stadium | Attendance | Top Batter | Top Pitcher | Playoffs |
| 1 | Winston-Salem Dash | CHW | 73 | 65 | .529 | -- | 626 | 642 | Joe McEwing | Gene Hooks Field at Wake | 57,665 | Brent Morel (4) | Anthony Carter (1) | Lost in Semi-Finals |
| 2 | Salem Red Sox | BOS | 67 | 72 | .482 | 6.5 | 600 | 599 | Chad Epperson | Lewis-Gale Field at Salem | 231,186 | Che-Hsuan Lin (11) | Eammon Portice (6) | Lost in Finals |
| 3 | Kinston Indians | CLE | 60 | 78 | .435 | 13.0 | 616 | 618 | Chris Tremie | Grainger Stadium | 133,049 | Cord Phelps (8) | Dallas Cawiezell (21) | |
| 4 | Myrtle Beach Pelicans | ATL | 53 | 84 | .387 | 19.5 | 550 | 711 | Rocket Wheeler | BB&T Coastal Field | 238,287 | Donell Linares (3) | Erik Cordier (8) | |