| Northern | ||||||||||||||
| Rk | Team | Affiliate | W | L | Pct | Gbl | RF | RA | Manager | Stadium | Attendance | Top Batter | Top Pitcher | Playoffs |
| 1 | Wilmington Blue Rocks | BOS | 67 | 71 | .486 | -- | 614 | 601 | Chad Epperson | Daniel S. Frawley Stadium | 312,258 | Jeff Corsaletti (11) | Mike James (16) | Lost in 1st Round |
| 2 | Potomac Nationals | WAN | 64 | 76 | .457 | 4.0 | 623 | 715 | Edgar Caceres | G. Richard Pfitzner Stadi | 151,507 | Brandon Powell (2) | Mike Hinckley (14) | - |
| 3 | Lynchburg Hillcats | PIT | 63 | 75 | .457 | 4.0 | 652 | 678 | Gary Green | Calvin Falwell Field | 157,744 | Michael Carlin (8) | Derek Hankins (13) | - |
| 4 | Frederick Keys | BAL | 61 | 77 | .442 | 6.0 | 637 | 1422 | Bien Figueroa | Harry Grove Stadium | 280,034 | Nolan Reimold (5) | Luis Ramirez (1) | Lost in finals |
| Southern | ||||||||||||||
| Rk | Team | Affiliate | W | L | Pct | Gbl | RF | RA | Manager | Stadium | Attendance | Top Batter | Top Pitcher | Playoffs |
| 1 | Kinston Indians ** | CLE | 85 | 54 | .612 | -- | 744 | 544 | Jim Rickon | Grainger Stadium | 112,253 | Jordan Brown (1) | Chuck Lofgren (4) | League Champions |
| 2 | Salem Avalanche | HOU | 76 | 61 | .555 | 8.0 | 582 | 518 | Jim Pankovits | Lewis-Gale Field at Salem | 237,724 | Drew Sutton (6) | Jimmy Barthmaier (8) | Lost in 1st Round |
| 3 | Myrtle Beach Pelicans | ATL | 72 | 68 | .514 | 13.5 | 599 | 673 | Rocket Wheeler | BB&T Coastal Field | 200,152 | Van Pope (3) | James Parr (19) | - |
| 4 | Winston-Salem Warthogs | CHW | 66 | 72 | .478 | 18.5 | 566 | 577 | Rafael Santana | Ernie Shore Field | 149,755 | Victor Mercedes (4) | Jack Egbert (7) | - |