| Rk | Team | Nickname | W | L | Pct | Gbl | Overall | RF | RA | Manager | Stadium | Top Batter | Top Pitcher | Playoffs |
| 1 | Texas | Longhorns | 19 | 7 | .731 | -- | 41-21 | 400 | 304 | Augie Garrido | UFCU Disch-Falk Field | Drew Stubbs (2) | Kyle McCulloch (13) | CWS Regionals, #12 in Nation |
| 2 | Oklahoma State | Cowboys | 18 | 9 | .667 | 1.5 | 41-20 | 443 | 334 | Frank Anderson | Allie P. Reynolds Stadium | Corey Brown (3) | Brae Wright (8) | CWS Regionals, #23 in Nation |
| 3 | Oklahoma | Sooners | 17 | 10 | .630 | 2.5 | 45-22 | 492 | 363 | Sunny Golloway | L. Dale Mitchell Park | Ryan Rohlinger (1) | Daniel McCutchen (2) | CWS Super-Regionals, #9 in Nation |
| 4 | Nebraska | Cornhuskers | 17 | 10 | .630 | 2.5 | 42-17 | 376 | 230 | Mike Anderson | Hawks Field | Ryan Wehrle (12) | Brett Jensen (4) | Conf Finalists, CWS Regionals, #15 in Nation |
| 5 | Baylor | Bears | 13 | 14 | .481 | 6.5 | 37-26 | 394 | 306 | Steve Smith | Baylor Ballpark | Seth Fortenberry (10) | Jake Weghorst (10) | CWS Regionals |
| 6 | Kansas ** | Jayhawks | 13 | 14 | .481 | 6.5 | 43-25 | 436 | 379 | Ritchie Price | Hoglund Ballpark | Jared Schweitzer (6) | Don Czyz (3) | Conf Champions, CWS Regionals |
| 7 | Missouri | Tigers | 12 | 15 | .444 | 7.5 | 35-28 | 403 | 256 | Tim Jamieson | Taylor Stadium | Zane Taylor (30) | Nathan Culp (1) | CWS Super-Regionals, #18 in Nation |
| 8 | Texas Tech | Red Raiders | 9 | 16 | .360 | 9.5 | 31-26-1 | 397 | 332 | Larry Hays | Dan Law Field | Matt Smith (17) | Miles Morgan (9) | - |
| 9 | Kansas State | Wildcats | 8 | 17 | .320 | 10.5 | 31-20-2 | 371 | 251 | Brad Hill | Tointon Family Stadium | Jared Goedert (11) | Adam Cowart (5) | - |
| 10 | Texas A&M | Aggies | 6 | 20 | .231 | 13.0 | 25-30-1 | 247 | 241 | Rob Childress | Olsen Field | Blake Stouffer (39) | Austin Creps (19) | - |