| 2012-04-07 | BOS | 31.327 | L 0-10 | @ DET | 1 | 280 | L | ST | 4.2 | 7 | 7 | 7 | 5 | 1 | 3 | 82 | 24 | 58 | 71% | 0-1 | 12.60 | 1.60 |
| 2012-04-13 | BOS | 31.333 | L 12-2 | vs TBA | 2 | 281 | W | ST | 8.0 | 5 | 1 | 1 | 0 | 1 | 1 | 94 | 33 | 61 | 65% | 1-1 | 5.54 | 1.08 |
| 2012-04-18 | BOS | 31.338 | W 3-6 | vs TEX | 3 | 282 | L | ST | 7.0 | 7 | 3 | 3 | 1 | 1 | 7 | 110 | 42 | 68 | 62% | 1-2 | 4.95 | 1.10 |
| 2012-04-24 | BOS | 31.344 | W 11-2 | @ MIN | 4 | 283 | W | ST | 6.0 | 5 | 2 | 2 | 0 | 3 | 5 | 97 | 35 | 62 | 64% | 2-2 | 4.50 | 1.15 |
| 2012-04-29 | BOS | 31.349 | L 1-4 | @ CHA | 5 | 284 | L | ST | 6.2 | 6 | 3 | 3 | 1 | 3 | 8 | 128 | 42 | 86 | 67% | 2-3 | 4.50 | 1.22 |
| 2012-05-04 |
| 2012-05-10 | BOS | 31.360 | W 3-8 | vs CLE | 6 | 285 | L | ST | 2.1 | 7 | 7 | 7 | 2 | 2 | 2 | 55 | 22 | 33 | 60% | 2-4 | 5.91 | 1.37 |
| 2012-05-15 | BOS | 32.000 | L 5-0 | vs SEA | 7 | 286 | W | ST | 7.0 | 4 | 0 | 0 | 0 | 2 | 9 | 92 | 33 | 59 | 64% | 3-4 | 4.93 | 1.29 |
| 2012-05-20 | BOS | 32.005 | W 5-1 | @ PHI | 8 | 287 | W | ST | 7.2 | 7 | 1 | 1 | 0 | 2 | 5 | 105 | 32 | 73 | 70% | 4-4 | 4.41 | 1.29 |
| 2012-05-26 | BOS | 32.011 | L 3-2 | vs TBA | 9 | 288 | - | ST | 7.0 | 4 | 2 | 2 | 0 | 0 | 5 | 90 | 22 | 68 | 76% | 4-4 | 4.18 | 1.20 |
| 2012-05-31 | BOS | 32.016 | W 3-7 | vs DET | 10 | 289 | L | ST | 7.0 | 10 | 4 | 4 | 0 | 1 | 1 | 102 | 35 | 67 | 66% | 4-5 | 4.29 | 1.24 |
| 2012-06-06 | BOS | 32.022 | W 1-2 | vs BAL | 11 | 290 | L | ST | 8.0 | 5 | 2 | 2 | 0 | 0 | 5 | 92 | 26 | 66 | 72% | 4-6 | 4.06 | 1.17 |
| 2012-06-11 | BOS | 32.027 | L 1-4 | @ MIA | 12 | 291 | L | ST | 7.0 | 6 | 4 | 4 | 0 | 1 | 5 | 96 | 32 | 64 | 67% | 4-7 | 4.15 | 1.15 |
| 2012-06-16 DL-15 Right shoulder soreness |
| 2012-06-30 Activated from DL |
| 2012-06-30 | BOS | 32.046 | L 2-3 | @ SEA | 13 | 292 | - | ST | 6.0 | 4 | 2 | 2 | 0 | 3 | 4 | 88 | 33 | 55 | 63% | 4-7 | 4.07 | 1.15 |
| 2012-07-06 | BOS | 32.052 | W 8-10 | vs NYA | 14 | 293 | - | ST | 5.0 | 8 | 6 | 6 | 0 | 2 | 5 | 90 | 41 | 49 | 54% | 4-7 | 4.45 | 1.20 |
| 2012-07-15 | BOS | 32.061 | W 7-3 | @ TBA | 15 | 294 | W | ST | 6.0 | 8 | 3 | 3 | 0 | 2 | 7 | 107 | 39 | 68 | 64% | 5-7 | 4.45 | 1.23 |
| 2012-07-20 | BOS | 32.066 | W 1-6 | vs TOR | 16 | 295 | L | ST | 6.0 | 7 | 5 | 4 | 0 | 3 | 7 | 94 | 34 | 60 | 64% | 5-8 | 4.54 | 1.26 |
| 2012-07-25 | BOS | 32.071 | L 3-5 | @ TEX | 17 | 296 | L | ST | 7.0 | 9 | 4 | 4 | 0 | 2 | 3 | 116 | 45 | 71 | 61% | 5-9 | 4.58 | 1.28 |
| 2012-07-31 | BOS | 32.077 | L 4-1 | vs DET | 18 | 297 | - | ST | 2.2 | 1 | 1 | 1 | 0 | 2 | 2 | 47 | 22 | 25 | 53% | 5-9 | 4.54 | 1.27 |
| 2012-08-08 | BOS | 32.085 | W 9-10 | vs TEX | 19 | 298 | - | ST | 5.0 | 8 | 8 | 8 | 3 | 2 | 2 | 86 | 28 | 58 | 67% | 5-9 | 4.97 | 1.30 |
| 2012-08-14 | BOS | 32.091 | L 1-7 | @ BAL | 20 | 299 | L | ST | 5.1 | 6 | 6 | 6 | 2 | 2 | 2 | 90 | 34 | 56 | 62% | 5-10 | 5.21 | 1.31 |
| 2012-08-19 | BOS | 32.096 | L 1-4 | @ NYA | 21 | 300 | L | ST | 6.0 | 7 | 4 | 4 | 2 | 3 | 6 | 104 | 43 | 61 | 59% | 5-11 | 5.24 | 1.33 |
| 2012-08-25 Traded from Red Sox with Adrian Gonzalez, Carl Crawford and Nick Punto to Dodgers for Jerry Sands, James Loney, Ivan DeJesus, Rubby de la Rosa and Allen Webster |
| 2012-08-27 | LAN | 32.104 | L 0-10 | @ COL | 22 | 301 | L | ST | 5.2 | 7 | 3 | 3 | 1 | 3 | 6 | 108 | 40 | 68 | 63% | 5-12 | 5.21 | 1.35 |
| 2012-09-01 | LAN | 32.109 | L 2-1 | vs ARI | 23 | 302 | W | ST | 6.2 | 6 | 1 | 1 | 1 | 1 | 9 | 100 | 32 | 68 | 68% | 6-12 | 5.01 | 1.33 |
| 2012-09-07 | LAN | 32.115 | L 2-5 | @ SFN | 24 | 303 | L | ST | 6.1 | 7 | 4 | 4 | 0 | 3 | 3 | 93 | 41 | 52 | 56% | 6-13 | 5.05 | 1.34 |
| 2012-09-13 | LAN | 32.121 | W 1-2 | vs SLN | 25 | 304 | - | ST | 5.1 | 7 | 1 | 1 | 0 | 2 | 6 | 96 | 40 | 56 | 58% | 6-13 | 4.95 | 1.36 |
| 2012-09-19 | LAN | 32.127 | W 7-6 | @ WAS | 26 | 305 | - | ST | 7.1 | 5 | 4 | 3 | 2 | 0 | 2 | 82 | 28 | 54 | 66% | 6-13 | 4.87 | 1.32 |
| 2012-09-25 | LAN | 32.133 | L 1-2 | @ SDN | 27 | 306 | L | ST | 5.2 | 5 | 2 | 1 | 0 | 2 | 7 | 102 | 41 | 61 | 60% | 6-14 | 4.77 | 1.32 |
| 2012-09-30 | LAN | 32.138 | L 7-1 | vs COL | 28 | 307 | W | ST | 6.0 | 6 | 1 | 1 | 1 | 3 | 5 | 91 | 32 | 59 | 65% | 7-14 | 4.66 | 1.33 |