| 2012-04-05 | TOR | 36.330 | W 7-4 | @ CLE | 1 | 754 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 11 | 5 | 6 | 55% | 0-0 | 0.00 | 1.00 |
| 2012-04-07 | TOR | 36.332 | W 7-4 | @ CLE | 2 | 755 | - | Rel | 1.0 | 3 | 1 | 1 | 0 | 0 | 0 | 30 | 13 | 17 | 57% | 0-0 | 4.50 | 2.00 |
| 2012-04-09 | TOR | 36.334 | W 2-4 | vs BOS | 3 | 756 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 10 | 3 | 7 | 70% | 0-0 | 3.00 | 1.33 |
| 2012-04-14 | TOR | 36.339 | W 4-6 | vs BAL | 4 | 757 | L | Rel | 1.0 | 2 | 2 | 2 | 1 | 0 | 2 | 16 | 7 | 9 | 56% | 0-1 | 6.75 | 1.50 |
| 2012-04-17 | TOR | 36.342 | L 7-3 | vs TBA | 5 | 758 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 1 | 2 | 21 | 8 | 13 | 62% | 0-1 | 5.40 | 1.60 |
| 2012-04-20 | TOR | 36.345 | W 4-3 | @ KCA | 6 | 759 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 1 | 1 | 16 | 7 | 9 | 56% | 0-1 | 4.50 | 1.50 |
| 2012-04-22 | TOR | 36.347 | W 5-3 | @ KCA | 7 | 760 | Sv | Rel | 1.0 | 2 | 1 | 1 | 0 | 1 | 0 | 22 | 8 | 14 | 64% | 0-1 | 5.14 | 1.71 |
| 2012-04-23 | TOR | 36.348 | W 4-1 | @ KCA | 8 | 761 | Sv | Rel | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 16 | 5 | 11 | 69% | 0-1 | 4.50 | 1.63 |
| 2012-04-27 | TOR | 36.352 | W 5-9 | vs SEA | 9 | 762 | - | Rel | 1.0 | 2 | 2 | 1 | 1 | 1 | 0 | 27 | 9 | 18 | 67% | 0-1 | 5.00 | 1.78 |
| 2012-04-29 | TOR | 36.354 | L 7-2 | vs SEA | 10 | 763 | - | Rel | 1.0 | 2 | 1 | 1 | 1 | 0 | 1 | 19 | 8 | 11 | 58% | 0-1 | 5.40 | 1.80 |
| 2012-05-01 | TOR | 36.356 | L 8-7 | vs TEX | 11 | 764 | W | Rel | 1.0 | 3 | 1 | 1 | 0 | 0 | 1 | 20 | 5 | 15 | 75% | 1-1 | 5.73 | 1.91 |
| 2012-05-08 |
| 2012-05-08 | TOR | 36.363 | L 3-7 | @ OAK | 12 | 765 | L | Rel | 0.1 | 3 | 5 | 5 | 1 | 2 | 0 | 27 | 19 | 8 | 30% | 1-2 | 9.82 | 2.36 |
| 2012-05-12 | TOR | 37.001 | W 2-1 | @ MIN | 13 | 766 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 1 | 1 | 31 | 15 | 16 | 52% | 1-2 | 9.00 | 2.33 |
| 2012-05-14 | TOR | 37.003 | W 1-7 | vs TBA | 14 | 767 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 12 | 3 | 9 | 75% | 1-2 | 8.31 | 2.23 |
| 2012-05-16 | TOR | 37.005 | L 8-1 | vs NYA | 15 | 768 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 2 | 5 | 71% | 1-2 | 7.71 | 2.07 |
| 2012-05-18 | TOR | 37.007 | L 14-5 | vs NYN | 16 | 769 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 16 | 8 | 8 | 50% | 1-2 | 7.20 | 2.00 |
| 2012-05-20 | TOR | 37.009 | W 5-6 | vs NYN | 17 | 770 | - | Rel | 0.1 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 3 | 100% | 1-2 | 6.75 | 1.88 |
| 2012-05-21 | TOR | 37.010 | W 6-2 | @ TBA | 18 | 771 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 10 | 4 | 6 | 60% | 1-2 | 6.35 | 1.76 |
| 2012-05-23 | TOR | 37.012 | L 4-5 | @ TBA | 19 | 772 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 20 | 7 | 13 | 65% | 1-2 | 6.00 | 1.72 |
| 2012-05-26 | TOR | 37.015 | L 7-8 | @ TEX | 20 | 773 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 15 | 7 | 8 | 53% | 1-2 | 5.68 | 1.63 |
| 2012-05-28 | TOR | 37.017 | L 6-2 | vs BAL | 21 | 774 | - | Rel | 0.1 | 4 | 2 | 2 | 0 | 0 | 1 | 26 | 9 | 17 | 65% | 1-2 | 6.63 | 1.84 |
| 2012-05-29 | TOR | 37.018 | L 8-6 | vs BAL | 22 | 775 | - | Rel | 0.2 | 0 | 0 | 0 | 0 | 0 | 1 | 12 | 4 | 8 | 67% | 1-2 | 6.30 | 1.75 |
| 2012-05-30 | TOR | 37.019 | L 4-1 | vs BAL | 23 | 776 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 10 | 3 | 7 | 70% | 1-2 | 6.00 | 1.67 |
| 2012-06-02 | TOR | 37.022 | W 4-7 | vs BOS | 24 | 777 | - | Rel | 0.2 | 0 | 0 | 0 | 0 | 1 | 0 | 14 | 6 | 8 | 57% | 1-2 | 6.00 | 1.71 |
| 2012-06-03 | TOR | 37.023 | L 5-1 | vs BOS | 25 | 778 | - | Rel | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 50% | 1-2 | 5.73 | 1.64 |
| 2012-06-05 | TOR | 37.025 | W 9-5 | @ CHA | 26 | 779 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 16 | 9 | 7 | 44% | 1-2 | 5.48 | 1.65 |
| 2012-06-07 | TOR | 37.027 | L 3-4 | @ CHA | 27 | 780 | L | Rel | 0.2 | 2 | 1 | 1 | 0 | 0 | 0 | 14 | 6 | 8 | 57% | 1-3 | 5.87 | 1.74 |
| 2012-06-08 | TOR | 37.028 | L 3-4 | @ ATL | 28 | 781 | L | Rel | 0.1 | 1 | 1 | 0 | 0 | 0 | 0 | 7 | 2 | 5 | 71% | 1-4 | 5.63 | 1.71 |
| 2012-06-11 | TOR | 37.031 | W 3-6 | vs WAS | 29 | 782 | - | Rel | 1.0 | 2 | 1 | 1 | 1 | 0 | 1 | 17 | 8 | 9 | 53% | 1-4 | 5.76 | 1.72 |
| 2012-06-13 | TOR | 37.033 | W 2-6 | vs WAS | 30 | 783 | - | Rel | 0.2 | 0 | 0 | 0 | 0 | 1 | 0 | 9 | 5 | 4 | 44% | 1-4 | 5.76 | 1.76 |
| 2012-06-16 | TOR | 37.036 | L 6-5 | vs PHI | 31 | 784 | W | Rel | 1.0 | 0 | 0 | 0 | 0 | 1 | 1 | 17 | 9 | 8 | 47% | 2-4 | 5.54 | 1.73 |
| 2012-06-18 | TOR | 37.038 | L 6-7 | @ MIL | 32 | 785 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 1 | 2 | 16 | 6 | 10 | 63% | 2-4 | 5.33 | 1.74 |
| 2012-06-19 | TOR | 37.039 | W 10-9 | @ MIL | 33 | 786 | - | Rel | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 14 | 5 | 9 | 64% | 2-4 | 5.14 | 1.75 |
| 2012-06-24 | TOR | 37.044 | L 0-9 | @ MIA | 34 | 787 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 13 | 5 | 8 | 62% | 2-4 | 4.97 | 1.69 |
| 2012-06-25 | TOR | 37.045 | W 9-6 | @ BOS | 35 | 788 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 17 | 9 | 8 | 47% | 2-4 | 4.80 | 1.67 |
| 2012-06-28 | TOR | 37.048 | W 7-9 | vs ANA | 36 | 789 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 1 | 2 | 19 | 8 | 11 | 58% | 2-4 | 4.65 | 1.68 |
| 2012-06-29 | TOR | 37.049 | L 7-5 | vs ANA | 37 | 790 | W | Rel | 0.2 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | 2 | 4 | 67% | 3-4 | 4.50 | 1.66 |
| 2012-07-01 | TOR | 37.051 | W 6-10 | vs ANA | 38 | 791 | L | Rel | 0.1 | 4 | 3 | 3 | 2 | 0 | 0 | 20 | 10 | 10 | 50% | 3-5 | 5.34 | 1.78 |
| 2012-07-05 | TOR | 37.055 | W 6-9 | vs KCA | 39 | 792 | - | Rel | 0.2 | 5 | 3 | 3 | 0 | 0 | 1 | 19 | 4 | 15 | 79% | 3-5 | 6.00 | 1.88 |
| 2012-07-16 | TOR | 37.066 | L 3-6 | @ NYA | 40 | 793 | - | Rel | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 100% | 3-5 | 6.00 | 1.88 |
| 2012-07-17 | TOR | 37.067 | L 1-6 | @ NYA | 41 | 794 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 13 | 4 | 9 | 69% | 3-5 | 5.82 | 1.82 |
| 2012-07-20 Traded from Blue Jays to Astros in 10-player deal |
| 2012-07-20 | HOU | 37.070 | L 8-13 | @ ARI | 42 | 795 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 4 | 6 | 60% | 3-5 | 5.66 | 1.77 |
| 2012-07-24 | HOU | 37.074 | W 2-4 | vs CIN | 43 | 796 | L | Rel | 0.2 | 3 | 3 | 3 | 1 | 2 | 0 | 29 | 16 | 13 | 45% | 3-6 | 6.25 | 1.86 |
| 2012-07-25 | HOU | 37.075 | W 3-5 | vs CIN | 44 | 797 | L | Rel | 0.2 | 2 | 3 | 3 | 0 | 1 | 2 | 27 | 9 | 18 | 67% | 3-7 | 6.81 | 1.89 |
| 2012-07-29 | HOU | 37.079 | L 9-5 | vs PIT | 45 | 798 | - | Rel | 0.2 | 0 | 0 | 0 | 0 | 0 | 2 | 13 | 4 | 9 | 69% | 3-7 | 6.81 | 1.89 |
| 2012-07-30 | HOU | 37.080 | L 7-8 | @ MIL | 46 | 799 | L | Rel | 1.0 | 4 | 2 | 2 | 0 | 1 | 0 | 21 | 10 | 11 | 52% | 3-8 | 7.11 | 1.97 |
| 2012-08-01 | HOU | 37.082 | L 4-13 | @ MIL | 47 | 800 | - | Rel | 1.0 | 4 | 3 | 3 | 1 | 0 | 1 | 28 | 10 | 18 | 64% | 3-8 | 7.62 | 2.03 |