| 1998-12-21 | George Williams | Signed as Free Agent by Twins. | C-OF | 5-10 | 190 | B | R | 1969-04-22 | La Crosse,WI | 1991- 24- 645-OAK
| MLB | 1995-2000 | 1990-2001 |
| 1998-12-18 | Jose Espinal | Claimed on waivers by Twins from Cubs | P | 6-1 | 185 | R | R | 1976-08-31 | Santo Domingo,DR | 1998- 16- 469-MIN
| AAA | | 1997-2007 |
| 1998-12-18 | Gary Rath | Signed as Free Agent by Twins. | P | 6-2 | 186 | L | L | 1973-01-10 | Gulfport,MS | 1994- 2- 47-LAN
| MLB | 1998-1999 | 1992-2005 |
| 1998-12-18 | Melvin Nieves | Signed by Twins | OF-RF | 6-2 | 220 | B | R | 1971-12-28 | San Juan,PR | 1988- 0- 0-ATL
| MLB | 1992-1998 | 1988-2008 |
| 1998-12-15 | Brent Gates | Signed as Free Agent by Twins. | 2B-3B | 6-1 | 190 | B | R | 1970-03-14 | Grand Rapids,MI | 1991- 1- 26-OAK
| MLB | 1993-1999 | 1991-1999 |
| 1998-12-15 | Melvin Nieves | Signed as Free Agent by Twins. | OF-RF | 6-2 | 220 | B | R | 1971-12-28 | San Juan,PR | 1988- 0- 0-ATL
| MLB | 1992-1998 | 1988-2008 |
| 1998-12-15 | Eddie Williams | Signed as Free Agent by Twins. | 3B-1B | 6-0 | 210 | R | R | 1964-11-01 | Shreveport,LA | 1983- 1- 4-NYN
| MLB | 1986-1998 | 1983-2002 |
| 1998-12-14 | Joe Espada | Selected by Twins from Athletics in Rule 5 major league draft | SS-2B | 5-10 | 175 | R | R | 1975-08-30 | Santurce,PR | 1996- 2- 45-OAK
| AAA | | 1994-2005 |
| 1998-12-14 | Brandon Marsters | Selected by Twins from Phillies in Rule 5 minor league draft | C-P | 5-11 | 206 | R | R | 1975-03-14 | Urbana,IL | 1996- 9- 256-PHI
| AAA | | 1994-2006 |
| 1998-12-14 | Alex Ochoa | Traded by Twins to Brewers for Darrell Nicholas. | OF-RF | 6-0 | 195 | R | R | 1972-03-29 | Miami Lakes,FL | 1991- 3- 82-BAL
| MLB | 1995-2002 | 1991-2008 |
| 1998-11-19 | Jon Shave | Claimed on waivers by Rangers from Twins. | 2B-SS | 6-0 | 185 | R | R | 1967-11-04 | Waycross,GA | 1990- 5- 144-TEX
| MLB | 1993-1999 | 1987-2001 |
| 1998-11-16 | Dan Naulty | Traded by Twins to Yankees for Allen Butler. | P | 6-6 | 224 | R | R | 1970-01-06 | Los Angeles,CA | 1992- 14- 402-MIN
| MLB | 1996-1999 | 1992-2000 |
| 1998-11-06 | J.C. Contreras | Signed as nondrafted free agent by Twins | P | 6-0 | 153 | L | L | 1982-04-24 | Caracas,VZ |
| A+ | | 2001-2004 |
| 1998-11-03 | Scott Downs | Traded by Cubs with Cash to Twins for Mike Morgan. | P | 6-2 | 190 | L | L | 1976-03-17 | Louisville,KY | 1997- 3- 94-CHN
| MLB | 2000-2014 | 1995-2014 |
| 1998-10-03 | Todd Ritchie | Released by Twins. | P | 6-3 | 222 | R | R | 1971-11-07 | Portsmouth,VA | 1990- 1- 12-MIN
| MLB | 1997-2004 | 1990-2008 |
| 1998-09-28 | Fred Rath | Claimed on waivers by Twins from Rockies. | P | 6-3 | 220 | R | R | 1973-01-05 | Dallas,TX | 1991- 29- 750-NYA
| MLB | 1998-1998 | 1995-2001 |
| 1998-08-25 | Mike Morgan | Traded by Twins to Cubs for Scott Downs and Cash. | P | 6-2 | 220 | R | R | 1959-10-08 | Tulare,CA | 1978- 1- 4-OAK
| MLB | 1978-2002 | 1978-2002 |
| 1998-07-31 | Matt Kinney | Traded by Red Sox with Joe Thomas and John Barnes to Twins for Greg Swindell and Orlando Merced. | P | 6-5 | 220 | R | R | 1976-12-16 | Bangor,ME | 1995- 6- 158-BOS
| MLB | 2000-2005 | 1995-2010 |
| 1998-07-31 | John Barnes | Traded by Red Sox with Joe Thomas and Matt Kinney to Twins for Greg Swindell and Orlando Merced. | OF-P | 6-2 | 205 | R | R | 1976-04-24 | San Diego,CA | 1996- 4- 121-BOS
| MLB | 2000-2001 | 1996-2007 |
| 1998-07-31 | Orlando Merced | Traded by Twins with Greg Swindell to Red Sox for Joe Thomas, Matt Kinney and John Barnes. | 1B-OF | 6-1 | 195 | L | R | 1966-11-02 | San Juan,PR | 1985- 0- 0-PIT
| MLB | 1990-2003 | 1986-2003 |
| 1998-07-31 | Greg Swindell | Traded by Twins with Orlando Merced to Red Sox for Joe Thomas, Matt Kinney and John Barnes. | P | 6-3 | 230 | R | L | 1965-01-02 | Fort Worth,TX | 1986- 1- 2-CLE
| MLB | 1986-2002 | 1986-2003 |
| 1998-06-25 | Fred Rath | Claimed on waivers by Rockies from Twins. | P | 6-3 | 220 | R | R | 1973-01-05 | Dallas,TX | 1991- 29- 750-NYA
| MLB | 1998-1998 | 1995-2001 |
| 1998-05-26 | Doug Linton | Signed as Free Agent by Twins. | P | 6-1 | 190 | R | R | 1965-09-02 | Santa Ana,CA | 1986- 43- 878-TOR
| MLB | 1992-2003 | 1984-2004 |
| 1998-05-22 | Ricky Bones | Released by Twins. | P-OF | 6-0 | 202 | R | R | 1969-04-07 | Salinas,PR | 1986- 0- 0-SDN
| MLB | 1991-2001 | 1986-2003 |
| 1998-04-20 | Chris Turner | Released by Twins. | C-1B | 6-3 | 200 | R | R | 1969-03-23 | Bowling Green,KY | 1991- 7- 194-CAL
| MLB | 1993-2000 | 1991-2000 |
| 1998-04-03 | Hector Carrasco | Claimed on waivers by Twins from Diamondbacks. | P | 6-2 | 220 | R | R | 1969-10-22 | San Pedro de Macoris,DR | 1988- 0- 0-NYN
| MLB | 1994-2007 | 1988-2012 |
| 1998-03-27 | Ryan Radmanovich | Claimed on waivers by Mariners from Twins. | OF-3B | 6-2 | 200 | L | R | 1971-08-09 | Calgary,AB | 1993- 14- 401-MIN
| MLB | 1998-1998 | 1993-2009 |
| 1998-02-06 | Chuck Knoblauch | Traded by Twins to Yankees for ??, Eric Milton, Cristian Guzman, Brian Buchanan and Cash. | 2B-LF | 5-9 | 170 | R | R | 1968-07-07 | Houston,TX | 1989- 1- 25-MIN
| MLB | 1991-2002 | 1987-2002 |
| 1998-02-06 | Brian Buchanan | Traded by Yankees with ??, Eric Milton, Cristian Guzman and Cash to Twins for Chuck Knoblauch. | OF-RF | 6-4 | 230 | R | R | 1973-07-21 | Miami,FL | 1994- 1- 24-NYA
| MLB | 2000-2004 | 1992-2009 |
| 1998-02-06 | Eric Milton | Traded by Yankees with ??, Cristian Guzman, Brian Buchanan and Cash to Twins for Chuck Knoblauch. | P | 6-3 | 220 | L | L | 1975-08-04 | State College,PA | 1996- 1- 20-NYA
| MLB | 1998-2009 | 1994-2009 |
| 1998-02-06 | Cristian Guzman | Traded by Yankees with ??, Eric Milton, Brian Buchanan and Cash to Twins for Chuck Knoblauch. | SS-2B | 6-0 | 188 | B | R | 1978-03-21 | Santo Domingo,DR | 1994- 0- 0-NYA
| MLB | 1999-2010 | 1996-2010 |
| 1998-01-14 | Orlando Merced | Signed as Free Agent by Twins. | 1B-OF | 6-1 | 195 | L | R | 1966-11-02 | San Juan,PR | 1985- 0- 0-PIT
| MLB | 1990-2003 | 1986-2003 |
| 1998-01-06 | Ricky Bones | Signed as Free Agent by Twins. | P-OF | 6-0 | 202 | R | R | 1969-04-07 | Salinas,PR | 1986- 0- 0-SDN
| MLB | 1991-2001 | 1986-2003 |