| 1952-12-10 | Mike Fornieles | Traded by Senators to White Sox for Chuck Stobbs. | P | 5-11 | 172 | R | R | 1932-01-18 | Havana,CU |
| MLB | 1952-1963 | 1952-1963 |
| 1952-12-10 | Chuck Stobbs | Traded by White Sox to Senators for Mike Fornieles. | P | 6-1 | 185 | L | L | 1929-07-02 | Wheeling,WV |
| MLB | 1947-1961 | 1947-1961 |
| 1952-12-02 | Carlos Pascual | Selected by Seattle (PCL) from Senators in the minor league draft. | P | 5-6 | 165 | R | R | 1931-03-13 | Havana,CU |
| MLB | 1950-1950 | 1950-1950 |
| 1952-10-07 | Tom Ferrick | Released by Senators. | P | 6-2 | 220 | R | R | 1915-01-06 | New York,NY |
| MLB | 1941-1952 | 1941-1952 |
| 1952-10-07 | Joe Haynes | Released by Senators. | P | 6-2 | 190 | R | R | 1917-09-21 | Lincolnton,GA |
| MLB | 1939-1952 | 1939-1952 |
| 1952-10-07 | Clyde Kluttz | Released by Senators. | C | 6-0 | 198 | R | R | 1917-12-12 | Rockwell,NC |
| MLB | 1942-1952 | 1942-1952 |
| 1952-09-23 | Wayne Terwilliger | Claimed on waivers by Senators from Dodgers. | 2B-3B | 5-11 | 170 | R | R | 1925-06-27 | Clare,MI |
| MLB | 1949-1960 | 1949-1960 |
| 1952-08-07 | Hal Keller | Purchased by Toronto (International) from Senators. | C | 6-1 | 200 | L | R | 1927-07-07 | Middletown,MD |
| MLB | 1949-1952 | 1949-1952 |
| 1952-06-16 | Bobo Newsom | Released by Senators. | P | 6-2 | 220 | R | R | 1907-08-11 | Hartsville,SC |
| MLB | 1929-1953 | 1929-1953 |
| 1952-06-10 | Walt Masterson | Traded by Red Sox with Randy Gumpert to Senators for Sid Hudson. | P | 6-2 | 189 | R | R | 1920-06-22 | Philadelphia,PA |
| MLB | 1939-1956 | 1939-1956 |
| 1952-06-10 | Fred Marsh | Traded by Senators to Browns for Earl Rapp. | 3B-SS | 5-10 | 180 | R | R | 1924-01-05 | Valley Falls,KS | 1942- 0- 0-CHN
| MLB | 1951-1956 | 1951-1956 |
| 1952-06-10 | Randy Gumpert | Traded by Red Sox with Walt Masterson to Senators for Sid Hudson. | P | 6-3 | 205 | R | R | 1918-01-23 | Monocacy,PA |
| MLB | 1936-1952 | 1936-1952 |
| 1952-06-10 | Earl Rapp | Traded by Browns to Senators for Fred Marsh. | OF | 6-2 | 185 | L | R | 1921-05-20 | Corunna,MI |
| MLB | 1949-1952 | 1949-1952 |
| 1952-06-10 | Sid Hudson | Traded by Senators to Red Sox for Randy Gumpert and Walt Masterson. | P | 6-4 | 180 | R | R | 1915-01-03 | Coalfield,TN |
| MLB | 1940-1954 | 1940-1954 |
| 1952-06-09 | Archie Wilson | Traded by Senators to Red Sox for Ken Wood. | OF | 6-0 | 175 | R | R | 1923-11-25 | Los Angeles,CA |
| MLB | 1951-1952 | 1951-1952 |
| 1952-06-09 | Ken Wood | Traded by Red Sox to Senators for Archie Wilson. | OF | 6-0 | 200 | R | R | 1924-07-01 | Lincolnton,NC |
| MLB | 1948-1953 | 1948-1953 |
| 1952-05-19 | Sherry Robertson | Claimed on waivers by Athletics from Senators. | OF-2B | 6-0 | 180 | L | R | 1919-01-01 | Montreal,QC |
| MLB | 1940-1952 | 1940-1952 |
| 1952-05-12 | Cass Michaels | Traded by Senators to Browns for Fred Marsh and Lou Sleater. | 2B-SS | 5-11 | 175 | R | R | 1926-03-04 | Detroit,MI |
| MLB | 1943-1954 | 1943-1954 |
| 1952-05-12 | Lou Sleater | Traded by Browns with Fred Marsh to Senators for Cass Michaels. | P | 5-10 | 185 | L | L | 1926-09-08 | St. Louis,MO |
| MLB | 1950-1958 | 1950-1958 |
| 1952-05-12 | Fred Marsh | Traded by Browns with Lou Sleater to Senators for Cass Michaels. | 3B-SS | 5-10 | 180 | R | R | 1924-01-05 | Valley Falls,KS | 1942- 0- 0-CHN
| MLB | 1951-1956 | 1951-1956 |
| 1952-05-03 | Irv Noren | Traded by Senators with Tom Upton to Yankees for Archie Wilson, Jerry Snyder, Spec Shea and Jackie Jensen. | OF-1B | 6-0 | 190 | L | L | 1924-11-29 | Jamestown,NY |
| MLB | 1950-1960 | 1950-1960 |
| 1952-05-03 | Archie Wilson | Traded by Yankees with Jerry Snyder, Spec Shea and Jackie Jensen to Senators for Tom Upton and Irv Noren. | OF | 6-0 | 175 | R | R | 1923-11-25 | Los Angeles,CA |
| MLB | 1951-1952 | 1951-1952 |
| 1952-05-03 | Sam Mele | Traded by Senators to White Sox for Mel Hoderlein and Jim Busby. | OF-1B | 6-1 | 187 | R | R | 1923-01-21 | Astoria,NY |
| MLB | 1947-1956 | 1947-1956 |
| 1952-05-03 | Tom Upton | Traded by Senators with Irv Noren to Yankees for Archie Wilson, Jerry Snyder, Spec Shea and Jackie Jensen. | SS-2B | 6-0 | 160 | R | R | 1926-12-29 | Esther,MO |
| MLB | 1950-1952 | 1950-1952 |
| 1952-05-03 | Mel Hoderlein | Traded by White Sox with Jim Busby to Senators for Sam Mele. | 2B-SS | 5-10 | 185 | B | R | 1923-06-24 | Mount Carmel,OH |
| MLB | 1951-1954 | 1951-1954 |
| 1952-05-03 | Jim Busby | Traded by White Sox with Mel Hoderlein to Senators for Sam Mele. | OF-3B | 6-1 | 175 | R | R | 1927-01-08 | Kenedy,TX |
| MLB | 1950-1962 | 1950-1962 |
| 1952-05-03 | Spec Shea | Traded by Yankees with Archie Wilson, Jerry Snyder and Jackie Jensen to Senators for Tom Upton and Irv Noren. | P | 6-0 | 195 | R | R | 1920-10-02 | Naugatuck,CT |
| MLB | 1947-1955 | 1947-1955 |
| 1952-05-03 | Jackie Jensen | Traded by Yankees with Archie Wilson, Jerry Snyder and Spec Shea to Senators for Tom Upton and Irv Noren. | OF | 5-11 | 190 | R | R | 1927-03-09 | San Francisco,CA |
| MLB | 1950-1961 | 1950-1961 |
| 1952-05-03 | Jerry Snyder | Traded by Yankees with Archie Wilson, Spec Shea and Jackie Jensen to Senators for Tom Upton and Irv Noren. | SS-2B | 6-0 | 170 | R | R | 1929-07-21 | Jenks,OK |
| MLB | 1952-1958 | 1952-1958 |
| 1952-04-22 | Mickey Harris | Claimed on waivers by Indians from Senators. | P | 6-0 | 195 | L | L | 1917-01-30 | New York,NY |
| MLB | 1940-1952 | 1940-1952 |
| 1952-02-01 | Mike McCormick | Released by Senators. | OF | 6-0 | 200 | R | R | 1917-05-06 | Angels Camp,CA |
| MLB | 1940-1951 | 1940-1951 |
| 1952-01-01 | Juan Delis | Signed as undrafted amateur Free Agent by Senators. | 3B-OF | 5-11 | 170 | R | R | 1928-02-27 | Santiago,CU |
| MLB | 1955-1955 | 1955-1955 |
| 1952-01-01 | Julio Becquer | Signed as undrafted amateur Free Agent by Senators. | 1B-OF | 5-11 | 178 | L | L | 1931-12-20 | Havana,CU |
| MLB | 1955-1963 | 1955-1963 |
| 1952-01-01 | Ted Abernathy | Signed as undrafted amateur Free Agent by Senators. | P | 6-4 | 215 | R | R | 1933-03-06 | Stanley,NC |
| MLB | 1955-1972 | 1952-1972 |