| 1 | 55 | June-Reg | Nick Hagadone | P | 21 | 6-5 | 230 | L | L | AA | | University of Washington | $571,500 |
| 1 | 62 | June-Reg | Ryan Dent | SS/2B | 18 | 6-0 | 190 | R | R | AA | | Wilson (Long Beach,CA) | $571,000 |
| 2 | 84** | June-Reg | Hunter Morris | 1B | 18 | 6-2 | 200 | L | R | College | | Grissom (Huntsville,AL) | |
| 3 | 114 | June-Reg | Brock Huntzinger | P | 18 | 6-3 | 200 | R | R | AA | | Pendelton Heights (Anderson,IN) | $225,000 |
| 4 | 144 | June-Reg | Chris Province | P | 22 | 6-4 | 220 | R | R | AA | | Southeastern Louisiana University | $120,000 |
| 5 | 174 | June-Reg | Will Middlebrooks | 3B/P | 18 | 6-3 | 197 | R | R | AA | | Liberty Eylau (Texarkana,TX) | $925,000 |
| 6 | 204 | June-Reg | Anthony Rizzo | 1B/P | 17 | 6-3 | 220 | L | L | AA | | Stoneman Douglas (Parkland,FL) | $325,000 |
| 7 | 234 | June-Reg | David Mailman | 1B | 18 | 6-2 | 180 | L | L | AA | | Providence (Charlotte,NC) | $550,000 |
| 8 | 264 | June-Reg | Adam Mills | P | 22 | 6-0 | 190 | R | R | AAA | | University of North Carolina-Charlotte | $25,000 |
| 9 | 294 | June-Reg | Kade Keowen | OF | 21 | 6-5 | 215 | R | R | AA | | Louisiana State University-Eunice | $123,000 |
| 10 | 324 | June-Reg | Kenneth Roque | SS | 17 | 5-11 | 162 | L | R | A- | | Puerto Rico Baseball Academy (Gurabo,PR) | $70,000 |
| 11 | 354 | June-Reg | Ryan Pressly | P | 18 | 6-3 | 175 | R | R | A- | | Marcus (Flower Mound,TX) | |
| 12 | 384 | June-Reg | Eammon Portice | P | 22 | 6-2 | 185 | R | R | A+ | | High Point University | |
| 13 | 414 | June-Reg | Justin Grimm | P | 18 | 6-4 | 170 | R | R | College | | Virginia (Bristol,VA) | |
| 14 | 443 | June-Reg | Jake Cowan | P | 19 | 6-3 | 175 | L | R | A- | | Roswell (Roswell,GA) | |
| 15 | 474 | June-Reg | Scott Green | P | 21 | 6-7 | 240 | R | R | A+ | | University of Kentucky | |
| 16 | 504 | June-Reg | Austin Bailey | P | 18 | 6-1 | 195 | S | R | A | | Prattville (Prattville,AL) | |
| 17 | 534 | June-Reg | Jaren Matthews | 1B/OF | 18 | 6-2 | 215 | L | L | College | | Don Bosco Prep (Ramsey,NJ) | |
| 18 | 564 | June-Reg | Hunter Strickland | P | 18 | 6-5 | 200 | R | R | AA | | Pike County (Zebulon,GA) | |
| 19 | 594 | June-Reg | David Marks | OF | 20 | 6-1 | 190 | L | R | AA | | Edmonds Community College | |
| 20 | 624 | June-Reg | Dan Milano | C | 21 | 6-1 | 215 | R | R | A- | | Northeastern University | |
| 21 | 654 | June-Reg | Aaron Reza | SS | 22 | 5-8 | 185 | R | R | A+ | | University of Oklahoma | |
| 22 | 684 | June-Reg | Will Latimer | P | 21 | 6-3 | 200 | L | L | AA | | Trinidad State Junior College | |
| 23 | 714 | June-Reg | Drake Britton | P | 18 | 6-2 | 200 | L | L | A- | | Tomball (Tomball,TX) | |
| 24 | 744 | June-Reg | Matt Presley | 3B | 18 | 6-3 | 210 | R | R | College | | Cheyenne Mountain (Colorado Springs,CO) | |
| 25 | 774 | June-Reg | Seth Garrison | P | 21 | 6-5 | 220 | B | R | A+ | | Texas Christian University | |
| 26 | 804 | June-Reg | Deshaun Brooks | 3B | 22 | 6-4 | 240 | R | R | A- | | Benedict College | |
| 27 | 834 | June-Reg | Yasmani Grandal | C | 18 | 6-2 | 215 | B | R | College | | Miami Springs (Miami Springs,FL) | |
| 28 | 864 | June-Reg | Nick Tepesch | P | 18 | 6-4 | 200 | R | R | College | | Blue Springs (Blue Springs,MO) | |
| 29 | 894** | June-Reg | Junior Carlin | P | 19 | 6-1 | 170 | L | L | College | | Riverview (Sarasota,FL) | |
| 30 | 924 | June-Reg | Will Vazquez | C | 22 | 6-1 | 190 | R | R | College | | Kent State University | |
| 31 | 954 | June-Reg | Daniel Buller | P | 22 | 6-1 | 215 | R | L | A | | Fresno City College | |
| 32 | 983 | June-Reg | Ridge Carpenter | OF | 18 | 6-0 | 170 | L | R | - | | Kalani (Honolulu,HI) | |
| 33 | 1012 | June-Reg | Garrett Larsen | P | 19 | 6-4 | 190 | R | R | - | | Texarkana College | |
| 34 | 1041 | June-Reg | Tony Bajoczky | P | 22 | 6-0 | 170 | R | R | AA | | Duke University | |
| 35 | 1070 | June-Reg | Sean Tierney | P | 18 | 6-5 | 180 | L | L | College | | Clover Hill (Midlothian,VA) | |
| 36 | 1099 | June-Reg | Scott Lyons | SS | 20 | 6-0 | 175 | R | R | College | | Mt. San Jacinto College | |
| 37 | 1127 | June-Reg | Scott Lonergan | P | 23 | 6-5 | 215 | R | R | AAA | | Rice University | |
| 38 | 1155 | June-Reg | Derrick Stultz | P | 18 | 6-3 | 220 | R | R | College | | Wharton (Tampa,FL) | |
| 39 | 1183 | June-Reg | Jonathan Roof | SS | 18 | 6-1 | 155 | R | R | College | | St. Mary's (Paducah,KY) | |
| 40 | 1211 | June-Reg | Ryan Fischer | P | 18 | 6-0 | 180 | R | R | - | | Lodi (Lodi,CA) | |
| 41 | 1237 | June-Reg | Mike Bourdon | C | 18 | 6-3 | 215 | R | R | College | | Northwest Catholic (West Hartford,CT) | |
| 42 | 1263 | June-Reg | Chad Povich | P | 21 | 6-1 | 190 | R | R | AA | | Dixie State College of Utah | |
| 43 | 1289 | June-Reg | Scott Cure | P | 18 | 6-3 | 190 | L | L | - | | Idalia (Idalia,CO) | |
| 44 | 1315 | June-Reg | Emmanuel Solano | SS | 24 | 5-9 | 165 | B | R | Rookie | | Miami-Dade College | |
| 45 | 1340 | June-Reg | Peter Gilardo | C | 21 | 6-0 | 200 | R | R | A | | Dominican College | |
| 46 | 1364 | June-Reg | Garrett Young | OF | 22 | 6-3 | 225 | R | R | College | | Liberty University | |
