| # | Player Name | Pos | Team | Age | Born | Ht | Wt | B-T | High Level | MLB Years | Drafted From | # |
| 1266. | Grant Theophilus | P | TB | 18 | 4/22/1985 | | | L-L | College | | Ocean View High School (Huntington Beach,CA) | 13 |
| 1267. | Daryl Maday | P | MIL | 17 | 8/12/1985 | 6-2 | 225 | R-R | AA | | Westocha Central High School (Bristol,WI) | 1 |
| 1268. | Brian Santo | P | DET | 22 | 10/26/1980 | 6-8 | 240 | R-R | A | | Mount St. Mary's College | 1 |
| 1269. | Nathan Rogers | P | SD | 20 | 10/11/1982 | 6-3 | 215 | L-L | Rookie | | Connors State College | 57 |
| 1270. | Matt Mallory | P | KC | 18 | 3/4/1985 | 6-3 | 220 | R-R | A | | Grand Junction Central High School (Grand Junction,CO) | 2 |
| 1271. | Brandon Harmon | P | CHC | 18 | 5/10/1985 | 6-5 | 200 | R-R | College | | Shadle Park High School (Spokane,WA) | 7 |
| 1272. | Kyle George | SS | BAL | 21 | 10/14/1981 | 6-0 | 195 | R-R | Ind | | University of Maryland | 65 |
| 1273. | Lance Scoggins | P | PIT | 18 | 1/19/1985 | 6-1 | 165 | L-L | College | | Bolton High School (Arlington,TN) | 1 |
| 1274. | Hunter Harrigan | C | TEX | 20 | 4/17/1983 | 6-1 | 210 | R-R | AAA | | Cowley County Community College | 30 |
| 1275. | Justin Jameson | OF | COL | 17 | 7/12/1985 | | | L-L | - | | Creekside High School (Fairburn,GA) | 2 |
| 1276. | Joe Weaver | P | CLE | 21 | 8/17/1981 | 6-4 | 195 | R-R | A- | | Oklahoma State University | 170 |
| 1277. | Mike Chambless | C | NYM | 18 | 2/9/1985 | 6-2 | 175 | R-R | - | | Round Rock High School (Round Rock,TX) | 10 |
| 1278. | Ryan Gordon | P | TOR | 22 | 1/27/1981 | 5-11 | 180 | L-L | College | | University of North Carolina-Greensboro | 10 |
| 1279. | Nick Devito | 1B | CIN | 18 | 10/22/1984 | 6-6 | 225 | R-R | College | | Hingham High School (Hingham,MA) | 3 |
| 1280. | Dustin Shafer | SS | CHW | 18 | 3/31/1985 | 6-3 | 185 | R-R | Rookie | | Russell High School (Russell,KY) | 2 |
| 1281. | Jared Johnson | P | FLA | 18 | 9/15/1984 | 6-2 | 200 | R-R | Ind | | | |
| 1282. | Scott Thomas | C | BOS | 18 | 3/21/1985 | 5-11 | 202 | L-R | A- | | chaminade College Prep School High School (St. Louis,MO) | 1 |
| 1283. | Cole Buchanan | P | PHI | 18 | 3/15/1985 | 6-2 | 165 | L-L | - | | Santiago High School (Corona,CA) | 1 |
| 1284. | Harold Williams | P | SEA | 18 | 9/23/1984 | 6-3 | 180 | L-L | A+ | | Cerritos College | 150 |
| 1285. | Anthony Savio | P | MTL | 18 | 9/6/1984 | 6-4 | 195 | R-R | - | | American River College | 5 |
| 1286. | Travis Kalin | SS | MIN | 18 | 7/30/1984 | 6-3 | 180 | R-R | Rookie | | Bishop Moore High School (Orlando,FL) | 6 |
| 1287. | Caleb Hatfield | P | ANA | 18 | 12/19/1984 | 5-7 | 210 | R-R | - | | Red Bluff High School (Red Bluff,CA) | 4 |
| 1288. | Clayton Van Hook | SS | LA | 18 | 1/18/1985 | 5-10 | 170 | B-R | - | | Brenham High School (Brenham,TX) | 1 |
| 1289. | Mike Bell | C | SF | 18 | 3/30/1985 | 5-11 | 175 | R-R | AA | | Red Bluff High School (Red Bluff,CA) | 5 |
| 1290. | Justin Berg | P | NYY | 19 | 6/7/1984 | 6-3 | 190 | R-R | AAA | | Indian Hills Community College-Centerville | 86 |
| 1291. | Max Scherzer | P | STL | 18 | 7/27/1984 | 6-3 | 190 | R-R | MLB | 2008-2008 | Parkway Central High School (Chesterfield,MO) | 3 |
| 1292. | Matt Mammen | P | ARI | 20 | 2/26/1983 | 6-2 | 180 | L-L | - | | St. Charles Community College | 3 |
| 1293. | Zechry Zinicola | P | ATL | 18 | 3/2/1985 | 6-1 | 220 | R-R | AA | | Arlington High School (Riverside,CA) | 13 |
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