| 1 | 8 | June-Reg | Scott Moore | SS | 18 | 6-2 | 180 | L | R | MLB | 2006-2008 | Cypress (Cypress,CA) | $2,300,000 |
| 2 | 49 | June-Reg | Brent Clevlen | OF | 18 | 6-2 | 190 | R | R | MLB | 2006-2008 | Westwood (Austin,TX) | $805,000 |
| 3 | 80 | June-Reg | Curtis Granderson | OF | 21 | 6-1 | 180 | L | R | MLB | 2004-2009 | University of Illinois | $469,000 |
| 3 | 87 | June-Reg | Matt Pender | P | 21 | 6-5 | 210 | R | R | A+ | | Kennesaw State University | |
| 4 | 110 | June-Reg | Robbie Sovie | OF | 18 | 6-0 | 200 | R | R | A- | | Steubenville (Steubenville,OH) | |
| 5 | 140 | June-Reg | Bo Flowers | OF | 18 | 6-0 | 180 | R | R | A | | Walther Lutheran (Melrose Park,IL) | |
| 6 | 170 | June-Reg | Chris Maples | 3B | 22 | 5-10 | 180 | R | R | AAA | | University of North Carolina | |
| 7 | 200 | June-Reg | Wilton Reynolds | OF | 22 | 6-4 | 190 | R | R | AAA | | Oral Roberts University | |
| 8 | 230 | June-Reg | Troy Pickford | P | 22 | 6-8 | 220 | R | R | A- | | Oral Roberts University | |
| 9 | 260 | June-Reg | Marcos Hernandez | P | 18 | 6-4 | 200 | L | L | Rookie | | Juan Ponce De Leon (Sabana Hoyos,PR) | |
| 10 | 290 | June-Reg | Luke Carlin | C | 21 | 5-11 | 180 | B | R | MLB | 2008-2009 | Northeastern University | |
| 11 | 320 | June-Reg | Joel Zumaya | P | 17 | 6-3 | 210 | R | R | MLB | 2006-2009 | Bonita Vista (Chula Vista,CA) | |
| 12 | 350 | June-Reg | Corey Hamman | P | 22 | 6-2 | 190 | L | L | AAA | | Montclair State University | |
| 13 | 380** | June-Reg | Anthony Reyes | P | 20 | 6-2 | 215 | R | R | MLB | 2005-2009 | USC | |
| 14 | 410 | June-Reg | Jason Graham | P | 22 | 6-3 | 190 | R | R | A- | | University of Central Florida | |
| 15 | 440 | June-Reg | Jesse Carlson | P | 21 | 6-1 | 160 | L | L | MLB | 2008-2009 | University of Connecticut | |
| 16 | 470 | June-Reg | Michael Smith | P | 20 | 6-5 | 205 | L | L | Rookie | | Valdosta State University | |
| 17 | 500 | June-Reg | Rob Watson | IF | 22 | 5-10 | 180 | R | R | A+ | | Oklahoma State University | |
| 18 | 530** | June-Reg | Jacob Coash | P | 18 | 6-4 | 220 | L | L | - | | Canyon (Canyon Country,CA) | |
| 19 | 560 | June-Reg | Rafael Mendez | 3B | 18 | 6-0 | 190 | R | R | A+ | | Notre Dame (Caguas,PR) | |
| 20 | 590 | June-Reg | Jason Kennedy | OF | 22 | 6-3 | 200 | R | R | A | | University of Minnesota | |
| 21 | 620 | June-Reg | Corey Loomis | IF | 21 | 6-1 | 180 | L | R | A- | | Bowling Green State University | |
| 22 | 650** | June-Reg | Cameron McGuire | C | 18 | 6-3 | 205 | R | R | Ind | | South Grand Prairie (Grand Prairie,TX) | |
| 23 | 680 | June-Reg | Drew Caravella | 1B | 22 | 6-2 | 210 | L | L | A- | | Ohio Wesleyan University | |
| 24 | 710 | June-Reg | Jody Roughton | 1B | 21 | 6-1 | 190 | L | R | AA | | University of Missouri | |
| 25 | 740 | June-Reg | Daniel Nelson | SS | | | 0 | | | - | | Crenshaw (Los Angeles,CA) | |
| 26 | 770 | June-Reg | Billy Kieninger | P | 22 | 6-4 | 200 | R | R | A+ | | Miami University | |
| 27 | 800 | June-Reg | Damien Myers | P | 21 | 6-0 | 180 | L | R | A+ | | Concordia College | |
| 28 | 830 | June-Reg | Everett Hancock | P | 22 | 6-0 | 180 | L | L | A- | | University of North Carolina | |
| 29 | 860 | June-Reg | Miguel Donate | 1B | | | 0 | | | - | | Juan Quirindongo Morell (Vega Alta,PR) | |
| 30 | 890 | June-Reg | David Garcia | OF | 20 | 6-0 | 160 | B | R | A- | | Santa Ana College | |
| 31 | 920 | June-Reg | Chris Mccuiston | | | | | | | College | | Michigan State University | |
| 32 | 950 | June-Reg | Douglas Webb | P | | | 0 | | | - | | Newbury Park (Newbury Park,CA) | |
| 33 | 980 | June-Reg | Jose Rodriguez | C | | | 0 | | | - | | Cypress College | |
| 34 | 1010 | June-Reg | Jason Allec | C | 21 | 6-3 | 200 | R | R | A+ | | Cal State Northridge | |
| 35 | 1040** | June-Reg | Brandon McCormick | P | 18 | 6-9 | 210 | R | R | - | | King Academy (Leesville,SC) | |
| 36 | 1070 | June-Reg | Chris Steinborn | P | 20 | 6-4 | 210 | L | L | AA | | Lake Land College | |
| 37 | 1100 | June-Reg | Ronnie Baron | | | | | | | College | | Blinn College | |
| 38 | 1130 | June-Reg | Ed Romprey | SS | 22 | 6-0 | 180 | R | R | AA | | Bellevue University | |
| 39 | 1160 | June-Reg | Kevin McDonald | C | 22 | 6-1 | 210 | L | R | A+ | | University of Maryland | |
| 40 | 1190 | June-Reg | Matt Taylor | | | | | | | College | | Antioch (Antioch,TN) | |
| 41 | 1220 | June-Reg | Edgar Ortiz | 1B | 23 | 6-3 | 220 | R | R | Rookie | | Compton Community College | |
| 42 | 1250** | June-Reg | Travis Simmons | 3B | 18 | 6-2 | 180 | R | R | - | | Cleveland (Cleveland,TN) | |
| 43 | 1279** | June-Reg | Corey McCoy | OF | 18 | 6-0 | 180 | R | R | - | | Pine Bluff (Pine Bluff,AR) | $0 |
| 44 | 1307 | June-Reg | Sean Richardson | C | 18 | 6-1 | 185 | R | R | Rookie | | Palomar College | |