| 469. | Tim Layden | P | TB | 18 | 12/22/1982 | 6-2 | 180 | L-L | AA | | Deer Park High School (Deer Park,NY) | 1 |
| 471. | Royce Hampton | P | TEX | 18 | 10/19/1982 | 6-2 | 170 | L-L | A | | Lehi High School (Lehi,UT) | 2 |
| 478. | Gene Desalme | P | MIL | 21 | 9/14/1979 | 6-5 | 210 | L-L | Ind | | Northwestern State University | 4 |
| 486. | Jason Vavao | 1B | CIN | 20 | 5/5/1981 | 6-4 | 220 | R-R | A+ | | Los Angeles Harbor Community College | 86 |
| 487. | Sean Smith | P | CLE | 17 | 10/13/1983 | 6-4 | 180 | R-R | AAA | | College Park High School (Pleasant Hill,CA) | 6 |
| 488. | Michael DiRosa | C | ARI | 21 | 1/17/1980 | 5-11 | 195 | R-R | AA | | University of Miami (Florida) | 169 |
| 489. | Sean Peless | IF | SEA | 20 | 12/24/1980 | 6-5 | 230 | L-L | A | - | Edmonds Community College | 46 |
| 493. | Chris Young | OF | CHW | 17 | 9/5/1983 | 6-2 | 170 | R-R | MLB | 2006-2008 | Bellaire High School (Bellaire,TX) | 23 |
| 495. | Roberto Santana | 1B | ATL | 18 | 3/2/1983 | 5-11 | 180 | L-R | Rookie | | Jose Collazo Colon High School (Juncos,PR) | 2 |
| 496. | Craig James | P | SF | 18 | 3/10/1983 | 6-1 | 170 | R-R | AA | | Miami Killian High School (Miami,FL) | 11 |