| 1 | 3 | June-Reg | Dewon Brazelton | P | 21 | 6-4 | 214 | R | R | MLB | 2002-2006 | Middle Tennessee State University | $2,500,000 |
| 2 | 47 | June-Reg | Jon Switzer | P | 21 | 6-3 | 190 | L | L | MLB | 2003-2009 | Arizona State University | $800,000 |
| 3 | 79 | June-Reg | Chris Flinn | P | 20 | 6-2 | 185 | R | R | AAA | | Stony Brook University | $470,000 |
| 4 | 109** | June-Reg | David Bush | P | 21 | 6-2 | 210 | R | R | MLB | 2004-2009 | Wake Forest University | |
| 5 | 139 | June-Reg | Chris Seddon | P | 17 | 6-3 | 170 | L | L | MLB | 2007-2007 | Canyon (Canyon Country,CA) | $325,000 |
| 6 | 169 | June-Reg | Matt Rico | OF | 19 | 6-3 | 200 | R | R | AA | | Freed-Hardeman University | $150,000 |
| 7 | 199 | June-Reg | Timothy King | P | 17 | 6-3 | 200 | L | L | A | | Deer Park (Deer Park,TX) | $132,000 |
| 8 | 229 | June-Reg | Aaron Clark | OF | 22 | 6-1 | 190 | L | L | AA | | University of Alabama | $25,000 |
| 9 | 259 | June-Reg | Fernando Cortez | IF | 19 | 6-1 | 170 | L | R | MLB | 2005-2007 | Grossmont College | $75,000 |
| 10 | 289 | June-Reg | Jason St. Clair | 2B | 18 | 5-10 | 170 | R | R | A+ | | Desert Vista (Phoenix,AZ) | $100,000 |
| 11 | 319** | June-Reg | Mark Worrell | P | 18 | 6-1 | 190 | R | R | MLB | 2008-2008 | John Leonard (Greenacres,FL) | |
| 12 | 349 | June-Reg | Pierre Blount | OF | 20 | 6-3 | 200 | R | R | A- | | Chaffey College | |
| 13 | 379 | June-Reg | Vince Harrison | 3B | 21 | 5-11 | 200 | R | R | AA | | University of Kentucky | |
| 14 | 409 | June-Reg | Thomas Nichols | 1B | 17 | 6-4 | 190 | R | R | A | | | |
| 15 | 439 | June-Reg | Eric Miller | IF | 23 | 6-2 | 175 | R | R | A+ | | Gulf Coast (Naples,FL) | |
| 16 | 469** | June-Reg | Tim Layden | P | 18 | 6-2 | 180 | L | L | AA | | Deer Park (Deer Park,NY) | |
| 17 | 499 | June-Reg | Michael Navaroli | P | 20 | 6-3 | 220 | R | R | A+ | | Indian River State College | |
| 18 | 529 | June-Reg | Jonny Gomes | OF | 20 | 6-1 | 205 | R | R | MLB | 2003-2009 | Santa Rosa Junior College | $25,000 |
| 19 | 559** | June-Reg | Jason Hammel | P | 18 | 6-6 | 200 | R | R | MLB | 2006-2009 | Treasure Valley Community College | |
| 20 | 589 | June-Reg | Jake Carney | P | 21 | 6-2 | 180 | R | R | A | | University of Dallas | |
| 21 | 619 | June-Reg | Jarod Matthews | P | 18 | 6-2 | 195 | R | R | AA | | Yelm (Yelm,WA) | |
| 22 | 649 | June-Reg | John-Paul Davis | 1B | 22 | 6-4 | 220 | R | R | AA | | Arkansas Tech University | |
| 23 | 679 | June-Reg | Brent Cordell | C | 21 | 6-3 | 210 | B | R | A+ | | Cosumnes River College | |
| 24 | 709 | June-Reg | Brian Wolotka | OF | 20 | 6-5 | 190 | L | L | A | | Valparaiso University | |
| 25 | 739** | June-Reg | Daron Roberts | C | 18 | 6-0 | 215 | R | R | AA | | Westview (Portland,OR) | |
| 26 | 769** | June-Reg | Josh Asanovich | 2B | 18 | 6-0 | 190 | R | R | AA | | Highland (Gilbert,AZ) | |
| 27 | 799 | June-Reg | Gabriel Martinez | 1B | 18 | 6-2 | 160 | L | R | AAA | | Blanca Malaret (Sabana Grande,PR) | |
| 28 | 829** | June-Reg | Mumba Rivera | | 20 | 6-5 | 205 | R | R | AAA | | Marshalltown Community College | |
| 29 | 859 | June-Reg | Josh Parker | P | 20 | 6-5 | 220 | R | R | AAA | | Wallace Community College | |
| 30 | 889 | June-Reg | Matt Wilkerson | | 18 | 6-2 | 215 | R | R | A | | Santa Margarita Catholic (Rancho Santa Margarita,CA) | |
| 31 | 919 | June-Reg | Diego Lopez | P | 17 | 6-4 | 190 | R | R | - | | Calexico (Calexico,CA) | |
| 32 | 949 | June-Reg | Joey Gathright | OF | 19 | 5-10 | 175 | L | R | MLB | 2004-2009 | | |
| 33 | 979 | June-Reg | Tyson Thompson | | 21 | 6-3 | 210 | R | R | A- | | Washington State University | |
| 34 | 1009 | June-Reg | Chad Gaudin | P | 18 | 5-11 | 165 | R | R | MLB | 2003-2009 | Crescent City Baptist (Harahan,LA) | |
| 35 | 1039** | June-Reg | Bryan Banks | P | | | 0 | | | - | | | |
| 36 | 1069** | June-Reg | Mike White | P | 18 | 6-2 | 210 | L | L | A- | | Countryside (Clearwater,FL) | |
| 37 | 1099** | June-Reg | Michael Rider | P | 17 | 6-3 | 210 | R | R | Rookie | | | |
| 38 | 1129** | June-Reg | Thomas Diamond | | 18 | 6-3 | 230 | R | R | AAA | | | |
| 39 | 1159** | June-Reg | Greg Dini | | 18 | 6-2 | 200 | R | R | A+ | | Bishop Moore (Orlando,FL) | |
| 40 | 1189 | June-Reg | Brett Davis | 1B | 19 | 6-4 | 175 | L | L | - | | Southern Union State Community College | |
| 41 | 1218 | June-Reg | Derek Acosta | P | 18 | 6-4 | 210 | R | R | - | | | |
| 42 | 1247 | June-Reg | Kevin Bertrand | | 20 | 6-4 | 220 | R | R | College | | College of the Sequoias | |
| 43 | 1275 | June-Reg | Griffin Zarbough | | 19 | 6-3 | 241 | L | L | Ind | | Wallace Community College | |
| 44 | 1303 | June-Reg | Danny Van Ruiten | P | 17 | 6-4 | 190 | R | R | Rookie | | St. John Bosco (Bellflower,CA) | |
| 45 | 1331 | June-Reg | Matt Lukevics | | 18 | 5-11 | 170 | R | R | College | | Jesuit (Tampa,FL) | |
| 46 | 1359 | June-Reg | Chris Eickhorst | C | 21 | 6-3 | 200 | R | R | AA | | Kean U. (Kean U.) | |
| 47 | 1387** | June-Reg | Eric Beattie | | 18 | 6-3 | 190 | R | R | A | | Riverview (Riverview,FL) | |
| 48 | 1414 | June-Reg | Brad Davis | C | 18 | 6-2 | 185 | R | R | AAA | | | |
| 49 | 1440 | June-Reg | Darwin Pittman | 1B | | | 0 | | | College | | East St. John (Reserve,LA) | |
| 50 | 1465 | June-Reg | Nick Aiello | P | 21 | 6-2 | 210 | L | L | A+ | | Oklahoma Christian University | |