| 1 | 11 | June-Reg | Mike Drumright | P | 21 | 6-4 | 210 | L | R | AAA | | Wichita State University | $970,000 |
| 2 | 41 | June-Reg | Brian Powell | P | 21 | 6-2 | 205 | R | R | MLB | 1998-2004 | University of Georgia | $270,000 |
| 3 | 70** | June-Reg | Chuck Crowder | P | 18 | 6-1 | 190 | L | L | AA | | Crestwood (Mantua,OH) | |
| 4 | 98 | June-Reg | Clay Bruner | P | 18 | 6-3 | 180 | R | R | AA | | Weatherford (Weatherford,OK) | |
| 5 | 126 | June-Reg | Rosario Ortiz | P | 20 | 6-4 | 215 | R | R | A- | | Arizona Western College | |
| 6 | 154 | June-Reg | Jeremiah Lignitz | C | 18 | 6-2 | 210 | L | R | A | | Davison (Davison,MI) | |
| 7 | 182 | June-Reg | Chris Manser | P-OF | 19 | 6-2 | 215 | R | R | Rookie | | Hillsborough (Tampa,FL) | |
| 8 | 210 | June-Reg | Scott Weaver | OF | | | | L | L | A | | University of Michigan | |
| 9 | 238 | June-Reg | Ronald Marietta | P | 17 | 6-0 | 190 | L | L | A | - | Bishop Ford (Brooklyn,NY) | |
| 10 | 266 | June-Reg | John Foran | P | 21 | 6-1 | 185 | R | R | A+ | | University of Central Florida | |
| 11 | 294 | June-Reg | Dave Borkowski | P | 18 | 6-1 | 200 | R | R | MLB | 1999-2008 | Sterling Heights (Sterling Heights,MI) | |
| 12 | 322 | June-Reg | Jason Lawrie | p | 18 | 6-2 | 175 | R | R | Ind | | Independence (San Jose,CA) | |
| 13 | 350** | June-Reg | Kevin Jordan | SS | 18 | 6-1 | 190 | R | R | A+ | | Lee (Midland,TX) | |
| 14 | 378 | June-Reg | Steve Hartsburg | SS | | | | | | Ind | | Schaumburg (Schaumburg,IL) | |
| 15 | 406** | June-Reg | Justin Lehr | p-C | 17 | 6-1 | 200 | R | R | MLB | 2004-2009 | West Covina (West Covina,CA) | |
| 16 | 434** | June-Reg | Mark Hendrickson | p | 21 | 6-9 | 230 | L | L | MLB | 2002-2009 | Washington State University | |
| 17 | 462 | June-Reg | Craig Caballero | OF | | | | | | - | | Grand Canyon University | |
| 18 | 490 | June-Reg | Brian Fuller | C | | | | | | A+ | | Northwestern University | |
| 19 | 518 | June-Reg | Lawyer Milloy | OF | | | | | | - | | University of Washington | |
| 20 | 546 | June-Reg | Ron Rojas | 2B | | | | | | A- | | Northwestern University | |
| 21 | 574** | June-Reg | Clint Bryant | 3B | 21 | 6-0 | 180 | R | R | A+ | | Texas Tech University | |
| 22 | 602 | June-Reg | J.R Webb | C | | | | | | - | | University of Texas | |
| 23 | 630 | June-Reg | Jay Waggoner | 1B-OF | | | | | | A+ | | Auburn University | |
| 24 | 658 | June-Reg | Peter Durkovic | p | 21 | 6-4 | 215 | L | L | AA | | Fordham University | |
| 25 | 686 | June-Reg | Robert Gray | OF | | | | | | - | | Embry-Riddle University | |
| 26 | 714** | June-Reg | Eric Valent | OF | 18 | 6-0 | 191 | L | L | MLB | 2001-2005 | Canyon (Anaheim,CA) | |
| 27 | 742** | June-Reg | Matt Thornton | p | 18 | 6-6 | 220 | L | L | MLB | 2004-2009 | Centerville (Sturgis,MI) | |
| 28 | 770 | June-Reg | Clausal Milord | OF | | | | | | A- | | New York Institute of Technology | |
| 29 | 798 | June-Reg | Mike Miller | 3B | | | | | | A- | | Hofstra University | |
| 30 | 826** | June-Reg | Jason Haynie | p | 21 | 6-0 | 194 | L | L | AAA | | University of South Carolina | |
| 31 | 854 | June-Reg | Darrell Hussman | p | 18 | 6-5 | 200 | R | R | A | | Quartz Hill (Quartz Hill,CA) | |
| 32 | 882 | June-Reg | Derek Mitchell | SS | 20 | 6-2 | 170 | R | R | AAA | | Triton College | |
| 33 | 910 | June-Reg | Derek Kopacz | 3B | 20 | 5-10 | 195 | R | R | A | | Triton College | |
| 34 | 938 | June-Reg | Luke Bonner | p | | | | | | A- | | Divine Child (Dearborn,MI) | |
| 35 | 966** | June-Reg | Chris Clark | Of | 20 | 6-1 | 180 | R | R | AA | | University of Arkansas | |
| 36 | 994 | June-Reg | Nathan Shipman | Of | 18 | 6-0 | 190 | B | R | Rookie | | River Ridge (New Port Richey,FL) | |
| 37 | 1022** | June-Reg | Greg Sprehn | p | | | | | | - | | Bangor (Bangor,WI) | |
| 38 | 1050** | June-Reg | John Kremer | p | 18 | 6-1 | 220 | R | R | AA | | Chatard (Indianapolis,IN) | |
| 39 | 1078** | June-Reg | Josh Davis | p | | | | | | - | | Pensacola Catholic (Pensacola,FL) | |
| 40 | 1106 | June-Reg | Mike Davis | SS | | | | | | - | | Chicago Vocational (Chicago,IL) | |
| 41 | 1134** | June-Reg | Phil Rosengren | p | 18 | 6-5 | 210 | R | R | A | | Day (Rye,NY) | |
| 42 | 1162 | June-Reg | Mike Whiteman | p | 20 | 6-2 | 185 | L | L | Ind | | Potomac State College of WVU | |
| 43 | 1190** | June-Reg | Robert Fick | C | 21 | 6-1 | 189 | L | R | MLB | 1998-2007 | Cal State Northridge | |
| 44 | 1218** | June-Reg | Jeremy Giambi | of | 20 | 6-0 | 200 | L | L | MLB | 1998-2003 | Cal State Fullerton | |
| 45 | 1244 | June-Reg | Errick Lowe | of | | | | | | - | | Lake Worth (Lake Worth,FL) | |
| 46 | 1269 | June-Reg | Doug Engleka | SS | | | | | | A | | Ohio University | |
| 47 | 1293** | June-Reg | Pedro Flores | p | 18 | 6-0 | 201 | L | L | AAA | | Sierra Vista (Baldwin Park,CA) | |
| 48 | 1315** | June-Reg | Brian Justine | p | | | | | | Ind | | Dwyer (West Palm Beach,FL) | |
| 49 | 1337 | June-Reg | Judd Van Winkle | p | 19 | 6-2 | 190 | L | L | Rookie | | Spartanburg Methodist College | |
| 50 | 1359 | June-Reg | Jose Nunez | 2B | | | | | | Ind | | Northeast Texas Community College | |
| 51 | 1380 | June-Reg | Gregory Ryan | ip | | | 0 | | | Rookie | | Divine Child (Dearborn,MI) | |
| 52 | 1399 | June-Reg | Maurice Watkins | p | | | | | | - | | Osser (Chicago,IL) | |
| 53 | 1418** | June-Reg | Bryan Houston | of | | | | | | - | | Escambia (Pensacola,FL) | |
| 54 | 1437 | June-Reg | Chad Cook | p | | | | | | - | | Fallbrook (Fallbrook,CA) | |
| 55 | 1455** | June-Reg | Mark Mulder | 1B | 17 | 6-6 | 200 | L | L | MLB | 2000-2008 | Thornwood (South Holland,IL) | |
| 56 | 1472 | June-Reg | Joe McFarlane | p | 18 | 6-3 | 185 | R | R | Rookie | | Anacortes (Anacortes,WA) | |
| 57 | 1487 | June-Reg | Gabe Kapler | 3B | 19 | 6-2 | 208 | R | R | MLB | 1998-2009 | Moorpark College | |
| 58 | 1501 | June-Reg | Brian Cummins | p | | | | | | A- | | Northwestern University | |
| 59 | 1514 | June-Reg | David Reinfelder | p | 21 | 6-1 | 180 | R | L | A- | | Michigan State University | |