| 2000 | Bowman | R | 395 | Roy Oswalt | Houston Astros |
| 2000 | Upper Deck | Black Diamond Rookie Edit | 145 | Roy Oswalt Team USA | |
| 2001 | Bowman | Best | 148 | Roy Oswalt | Houston Astros |
| 2001 | Bowman | Heritage | 360 | Roy Oswalt | Houston Astros |
| 2001 | Bowman | R | 237 | Roy Oswalt | Houston Astros |
| 2001 | Fleer | Platinum | 267 | Roy Oswalt, Ben Sheets Major League Rookies | |
| 2001 | Leaf | Limited | 355 | Roy Oswalt Bat | Houston Astros |
| 2001 | Leaf | Rookies and Stars | 207 | Roy Oswalt | Houston Astros |
| 2001 | Topps | Fusion | 64 | Roy Oswalt Gold Label | Houston Astros |
| 2001 | Topps | Gallery | 109 | Roy Oswalt Students of the Game | Houston Astros |
| 2001 | Topps | R | 727 | Roy Oswalt, Jon Rauch, Pat Strange Prospects | |
| 2001 | Topps | Traded | 75 | Roy Oswalt | Houston Astros |
| 2001 | Upper Deck | Ultimate Collection | 44 | Roy Oswalt | Houston Astros |
| 2002 | Bowman | Best | 83 | Roy Oswalt | Houston Astros |
| 2002 | Bowman | Heritage | 72 | Roy Oswalt | Houston Astros |
| 2002 | Bowman | R | 79 | Roy Oswalt | Houston Astros |
| 2002 | Donruss | Classics | 80 | Roy Oswalt | Houston Astros |
| 2002 | Donruss | Diamond Kings | 27 | Roy Oswalt | Houston Astros |
| 2002 | Donruss | Elite | 14 | Roy Oswalt | Houston Astros |
| 2002 | Donruss | Fan Club | 12 | Roy Oswalt | Houston Astros |
| 2002 | Donruss | Fan Club | 278 | Roy Oswalt Fan Club | Houston Astros |
| 2002 | Donruss | Originals | 364 | Roy Oswalt 1988 | Houston Astros |
| 2002 | Donruss | Originals | 267 | Roy Oswalt 1986 | Houston Astros |
| 2002 | Donruss | Originals | 144 | Roy Oswalt 1984 | Houston Astros |
| 2002 | Donruss | Originals | 54 | Roy Oswalt 1982 | Houston Astros |
| 2002 | Donruss | R | 112 | Roy Oswalt | Houston Astros |
| 2002 | Donruss | R | 215 | Roy Oswalt Fan Club | Houston Astros |
| 2002 | Donruss | Studio | 37 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Authentix | 112 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Box Score | 46 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Flair | 16 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Focus Jersey Edition | 118 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Maximum | 171 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Platinum | 267 | Roy Oswalt Building Blocks | Houston Astros |
| 2002 | Fleer | Premium | 92 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Tradition | 70 | Roy Oswalt | Houston Astros |
| 2002 | Fleer | Triple Crown | 84 | Roy Oswalt | Houston Astros |
| 2002 | Leaf | Certified | 67 | Roy Oswalt | Houston Astros |
| 2002 | Leaf | R | 118 | Roy Oswalt | Houston Astros |
| 2002 | Leaf | Rookies and Stars | 169 | Roy Oswalt | Houston Astros |
| 2002 | SP | Authentic | 44 | Roy Oswalt | Houston Astros |
| 2002 | SPx | R | 44 | Roy Oswalt | Houston Astros |
| 2002 | Topps | 206 | 104 | Roy Oswalt | Houston Astros |
| 2002 | Topps | 206 | 252 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Finest | 15 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Gallery | 134 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Gold Label | 82 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Heritage | 316 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Opening Day | 1 | Roy Oswalt | Houston Astros |
| 2002 | Topps | R | 69 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Reserve | 129 | Roy Oswalt | Houston Astros |
| 2002 | Topps | Total | 36 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | 40 Man | 459 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | 40 Man | 1132 | Roy Oswalt Rotation | Houston Astros |
| 2002 | Upper Deck | Ballpark Idols | 95 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | Diamond Connection | 44 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | MVP | 142 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | R | 257 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | Sweet Spot | 42 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | Victory | 243 | Roy Oswalt | Houston Astros |
| 2002 | Upper Deck | Vintage | 132 | Roy Oswalt | Houston Astros |
| 2003 | Bowman | Chrome | 63 | Roy Oswalt | Houston Astros |
| 2003 | Bowman | Heritage | 116 | Roy Oswalt | Houston Astros |
| 2003 | Bowman | R | 63 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Champions | 122 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Classics | 13 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Diamond Kings | 105 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Elite | 115 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | R | 293 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Signature | 40 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Studio | 133 | Roy Oswalt | Houston Astros |
| 2003 | Donruss | Team Heroes | 215 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Authentix | 72 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Box Score | 67 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Genuine | 48 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Hot Prospects | 42 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Platinum | 184 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Showcase | 57 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Splendid Splinters | 46 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Tradition | 484 | Roy Oswalt Banner Season | Houston Astros |
| 2003 | Fleer | Tradition | 13 | Roy Oswalt, Lance Berkman Astros Team Leaders | Houston Astros |
| 2003 | Fleer | Tradition Update | 153 | Roy Oswalt | Houston Astros |
| 2003 | Fleer | Ultra | 78 | Roy Oswalt | Houston Astros |
| 2003 | Leaf | Certified Materials | 70 | Roy Oswalt | Houston Astros |
| 2003 | Leaf | Limited | 74 | Roy Oswalt | Houston Astros |
| 2003 | Leaf | Limited | 114 | Roy Oswalt | Houston Astros |
| 2003 | Leaf | R | 178 | Roy Oswalt | Houston Astros |
| 2003 | SPx | R | 50 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Chrome | 38 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Finest | 87 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Gallery | 84 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Heritage | 297 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Opening Day | 139 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Pristine | 46 | Roy Oswalt | Houston Astros |
| 2003 | Topps | R | 210 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Stadium Club | 98 | Roy Oswalt | Houston Astros |
| 2003 | Topps | Total | 746 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | 40 Man | 357 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Classic Portraits | 6 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Finite | 42 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | First Pitch | 139 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Game Face | 172 | Roy Oswalt, Ken Griffey Faceoff | |
| 2003 | Upper Deck | Game Face | 47 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Honor Roll | 93 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Honor Roll | 94 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | MVP | 91 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Play Ball | 26 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | R | 139 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Victory | 36 | Roy Oswalt | Houston Astros |
| 2003 | Upper Deck | Vintage | 11 | Roy Oswalt | Houston Astros |
| 2004 | Bazooka | R | 134 | Roy Oswalt | Houston Astros |
| 2004 | Bowman | R | 75 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Classics | 55 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Diamond Kings | 134 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Elite | 108 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Elite Extra Edition | 108 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Leather and Lumber | 64 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | R | 282 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Studio | 93 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | Team Heroes | 186 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | ThrowBack Threads | 89 | Roy Oswalt | Houston Astros |
| 2004 | Donruss | World Series | 84 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Authentix | 54 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Classic Clippings | 55 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Genuine Insider | 45 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | National Pastime | 23 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Platinum | 108 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Showcase | 40 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Tradition | 372 | Roy Oswalt | Houston Astros |
| 2004 | Fleer | Ultra | 194 | Roy Oswalt | Houston Astros |
| 2004 | Leaf | Certified Cuts | 87 | Roy Oswalt | Houston Astros |
| 2004 | Leaf | Limited | 240 | Roy Oswalt | Houston Astros |
| 2004 | Leaf | Limited | 137 | Roy Oswalt | Houston Astros |
| 2004 | Leaf | R | 142 | Roy Oswalt | Houston Astros |
| 2004 | SP | Authentic | 29 | Roy Oswalt | Houston Astros |
| 2004 | SP | Prospects | 62 | Roy Oswalt | Houston Astros |
| 2004 | SPx | R | 16 | Roy Oswalt | Houston Astros |
| 2004 | Topps | Chrome | 428 | Roy Oswalt | Houston Astros |
| 2004 | Topps | Finest | 7 | Roy Oswalt | Houston Astros |
| 2004 | Topps | Heritage | 255 | Roy Oswalt | Houston Astros |
| 2004 | Topps | Opening Day | 139 | Roy Oswalt | Houston Astros |
| 2004 | Topps | R | 486 | Roy Oswalt | Houston Astros |
| 2004 | Topps | Total | 170 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | Etchings | 33 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | First Pitch | 139 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | Play Ball | 58 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | Power Up | 16 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | R | 139 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | R Class | 84 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | Reflections | 88 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | Vintage | 40 | Roy Oswalt | Houston Astros |
| 2004 | Upper Deck | Vintage | 308 | Roy Oswalt Play Ball | Houston Astros |
| 2005 | Bazooka | R | 128 | Roy Oswalt | Houston Astros |
| 2005 | Bowman | Heritage | 322 | Roy Oswalt | Houston Astros |
| 2005 | Bowman | R | 121 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Classics | 59 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Diamond Kings | 104 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Elite | 76 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | R | 211 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Studio | 138 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Team Heroes | 144 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Throwback Threads | 47 | Roy Oswalt | Houston Astros |
| 2005 | Donruss | Timeless Treasures | 44 | Roy Oswalt | Houston Astros |
| 2005 | Fleer | Tradition | 4 | Roy Oswalt, Roger Clemens, Carl Pavano NL Wins Leaders | |
| 2005 | Fleer | Tradition | 162 | Roy Oswalt | Houston Astros |
| 2005 | Fleer | Ultra | 31 | Roy Oswalt | Houston Astros |
| 2005 | Leaf | Century | 44 | Roy Oswalt | Houston Astros |
| 2005 | Leaf | Limited | 45 | Roy Oswalt | Houston Astros |
| 2005 | Leaf | R | 92 | Roy Oswalt | Houston Astros |
| 2005 | SP | Authentic | 84 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Chrome | 379 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Cracker Jack | 54 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Finest | 119 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Gallery | 96 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Heritage | 227 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Opening Day | 110 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Pack Wars | 113 | Roy Oswalt | Houston Astros |
| 2005 | Topps | R | 526 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Total | 75 | Roy Oswalt | Houston Astros |
| 2005 | Topps | Update | 127 | Roy Oswalt NLCS | Houston Astros |
| 2005 | Topps | Update | 130 | Roy Oswalt NLCS | Houston Astros |
| 2005 | Topps | Update | 144 | Roy Oswalt, Dontrelle Willis, Chris Carpenter NL Wins Leaders | |
| 2005 | Upper Deck | ESPN | 41 | Roy Oswalt | Houston Astros |
| 2005 | Upper Deck | First Pitch | 91 | Roy Oswalt | Houston Astros |
| 2005 | Upper Deck | MVP | 78 | Roy Oswalt | Houston Astros |
| 2005 | Upper Deck | Pros and Prospects | 98 | Roy Oswalt | Houston Astros |
| 2005 | Upper Deck | R | 91 | Roy Oswalt | Houston Astros |
| 2005 | Upper Deck | Sweet Spot | 77 | Roy Oswalt | Houston Astros |
| 2005 | Upper Deck | Trilogy | 85 | Roy Oswalt | Houston Astros |
| 2005 | Zenith | R | 47 | Roy Oswalt | Houston Astros |
| 2006 | Bazooka | R | 149 | Roy Oswalt | Houston Astros |
| 2006 | Bowman | Heritage | 174 | Roy Oswalt | Houston Astros |
| 2006 | Bowman | R | 139 | Roy Oswalt | Houston Astros |
| 2006 | Fleer | Flair Showcase | 21 | Roy Oswalt Upper Deck | Houston Astros |
| 2006 | Fleer | R | 26 | Roy Oswalt | Houston Astros |
| 2006 | Fleer | Tradition | 26 | Roy Oswalt | Houston Astros |
| 2006 | Fleer | Ultra | 10 | Roy Oswalt | Houston Astros |
| 2006 | SPx | R | 41 | Roy Oswalt | Houston Astros |
| 2006 | Topps | Chrome | 81 | Roy Oswalt | Houston Astros |
| 2006 | Topps | Co-Signers | 37 | Roy Oswalt | Houston Astros |
| 2006 | Topps | Finest | 87 | Roy Oswalt | Houston Astros |
| 2006 | Topps | Heritage | 306 | Roy Oswalt | Houston Astros |
| 2006 | Topps | Heritage | 400 | Andy Pettitte, Roger Clemens, Roy Oswalt Astros Aces | Houston Astros |
| 2006 | Topps | Opening Day | 114 | Roy Oswalt | Houston Astros |
| 2006 | Topps | R | 575 | Roy Oswalt | Houston Astros |
| 2006 | Topps | Triple Threads | 73 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | Artifacts | 38 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | Epic | 113 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | First Pitch | 88 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | Future Stars | 30 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | Ovation | 5 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | R | 217 | Roy Oswalt | Houston Astros |
| 2006 | Upper Deck | Sweet Spot Update | 41 | Roy Oswalt | Houston Astros |
| 2007 | Bowman | Heritage | 125 | Roy Oswalt | Houston Astros |
| 2007 | Bowman | R | 55 | Roy Oswalt | Houston Astros |
| 2007 | Fleer | R | 197 | Roy Oswalt | Houston Astros |
| 2007 | Fleer | Ultra | 73 | Roy Oswalt | Houston Astros |
| 2007 | SP | Authentic | 21 | Roy Oswalt | Houston Astros |
| 2007 | SPx | R | 69 | Roy Oswalt | Houston Astros |
| 2007 | Topps | Chrome | 153 | Roy Oswalt | Houston Astros |
| 2007 | Topps | Co-Signers | 12 | Roy Oswalt | Houston Astros |
| 2007 | Topps | Finest | 112 | Roy Oswalt | Houston Astros |
| 2007 | Topps | Heritage | 423 | Roy Oswalt | Houston Astros |
| 2007 | Topps | Opening Day | 173 | Roy Oswalt | Houston Astros |
| 2007 | Topps | Update | 248 | Roy Oswalt | Houston Astros |
| 2007 | Upper Deck | Future Stars | 40 | Roy Oswalt | Houston Astros |
| 2007 | Upper Deck | R | 719 | Roy Oswalt | Houston Astros |
| 2007 | Upper Deck | Spectrum | 69 | Roy Oswalt | Houston Astros |
| 2008 | Topps | Heritage | 235 | Roy Oswalt | Houston Astros |
| 2008 | Topps | Opening Day | 98 | Roy Oswalt | Houston Astros |
| 2008 | Topps | R | 220 | Roy Oswalt | Houston Astros |
| 2008 | Upper Deck | R | 11 | Roy Oswalt | Houston Astros |
