| Frank German | P | 21.322 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Jose Devers | SS | 19.247 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Ildemaro Escalona | SS | 20.179 | - | | Released by Gulf Coast Tigers East |
| Alvaro Gonzalez | SS | 18.328 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Jake Hirabayashi | C | 22.316 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Edgar Barclay | P | 21.078 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Kelvin Smith | 3B | 19.285 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Jose Larez | P | 22.210 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to Gulf Coast Red Sox (Rk) |
| Mariano Dotel | SS | 19.219 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Alejandro Vallejo | P | 20.279 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Rainier Rivas | | -- | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Kevin Strohschein | 1B | 22.016 | Washington Nationals | Gulf Coast Nationals (Rk) | |
| Hunter Oliver | C | 21.293 | Cincinnati Reds | Arizona Reds (Rk) | Assigned to Arizona Reds (Rk) |
| Braden Webb | P | 24.107 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Jesus Luzardo | P | 21.314 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Makesiondon Kelkboom | SS | 19.029 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Yovanny Cruz | P | 19.353 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Caleb Freeman | P | 21.168 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| Clayton Chatham | P | 24.042 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Hansen Butler | P | 23.285 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Nick Grande | SS | 21.182 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Edward Cuello | P | 20.294 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Ricky De La Torre | SS | 20.020 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Connor Grey | P | 25.096 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Kelvin Alarcon | 3B | 20.157 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Hector Hernandez | P | 28.171 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Michael Gibbons | P | 26.108 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Aaron McGarity | P | 24.191 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Taylor Varnell | P | 24.097 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Josh Maciejewski | P | 23.362 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Mickey Gasper | C | 23.304 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Josh Breaux | C | 21.307 | New York Yankees | Charleston (sc) (A) | Activated from disabled list |
| Zach Scott | 2B | 24.105 | Miami Marlins | Clinton (A) | DL-7 Injured |
| Ike Freeman | IF | 21.054 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Pablo Abreu | OF | 19.296 | Milwaukee Brewers | Wisconsin (A) | Activated from disabled list |
| Michael Wielansky | SS | 22.145 | Houston Astros | Quad Cities (A) | DL-7 Injured |
| CJ Abrams | SS | 18.311 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Orlando Marquez | C | 23.151 | Houston Astros | Quad Cities (A) | Activated from disabled list |
| DaShawn Keirsey | CF | 22.089 | Minnesota Twins | Cedar Rapids (A) | Activated from disabled list |
| Connor Fitzsimons | R | 24.346 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| Andy Cox | UT | 25.291 | Cincinnati Reds | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Connor Law | P | 25.105 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Ryan Kellogg | P | 25.187 | Chicago Cubs | Myrtle Beach (A+) | Reinstated to active roster |
| Kade McClure | P | 23.180 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Jeffrey Passantino | P | 23.320 | Chicago Cubs | Myrtle Beach (A+) | DL-7 Injured |
| Jarred Kelenic | OF | 20.025 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Max Gamboa | P | 23.262 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Willis Montgomerie | P | 24.069 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Activated from disabled list |
| Aaron Knapp | OF | 24.279 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Ofreidy Gomez | P | 24.035 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Damien Magnifico | P | 28.078 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Sam Lewis | P | 27.306 | Arizona Diamondbacks | Jackson (AA) | Activated from disabled list |
| Ryan Nutof | P | 23.282 | Cincinnati Reds | Chattanooga (AA) | DL-7 Injured |
| Ibandel Isabel | OF | 24.051 | Cincinnati Reds | Chattanooga (AA) | DL-7 Injured |
| Jonah Arenado | 3B | 24.188 | - | | Released by Richmond |
| Logan Webb | P | 22.265 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Jenrry Mejia | P | 29.303 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Jin-De Jhang | C | 26.085 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Brian Gonzalez | P | 23.290 | Baltimore Orioles | Bowie (AA) | DL-7 Injured |
| Alex Faedo | P | 23.272 | Detroit Tigers | Erie (AA) | DL-7 Injured |
| Marcos Molina | P | 24.155 | Baltimore Orioles | Bowie (AA) | Activated from disabled list |
| Yoanys Quiala | P | 25.207 | - | | Released by Sacramento |
| Bradin Hagens | P | 30.090 | Arizona Diamondbacks | Reno (AAA) | DL-7 Injured |
| Ben Moore | OF-C | 26.322 | Los Angeles Dodgers | Oklahoma City (AAA) | DL-7 Injured |
| Ricky Nolasco | P | 36.240 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Tom Windle | P | 27.153 | - | | Released by Lehigh Valley |
| Ian Miller | OF | 27.171 | Minnesota Twins | Rochester (AAA) | Traded to Twins from Mariners for cash |
| Ryan O'Rourke | P | 31.102 | Minnesota Twins | Rochester (AAA) | Signed to Minor League Contract |
| Nick Vincent | P | 33.029 | Philadelphia Phillies | Lehigh Valley (AAA) | Signed to Minor League Contract |
| Dylan Cozens | RF-OF | 25.071 | Tampa Bay Rays | Durham (AAA) | Signed to Minor League Contract |
| Harol Gonzalez | P | 24.161 | New York Mets | Syracuse (AAA) | DL-7 Injured |
| Matt Wotherspoon | P | 27.309 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Ian Krol | P | 28.093 | Minnesota Twins | Rochester (AAA) | Placed on restricted list |
| AJ Cole | RP | 27.218 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Injured |
| Hunter Wood | P | 25.363 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| David Paulino | P | 25.185 | | | Released by Blue Jays |
| Trevor Rosenthal | P | 29.073 | Detroit Tigers | Toledo (AAA) | Outrighted to minors |
| Sam Howard | P | 26.158 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Ryan Court | 1B-3B | 31.074 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Dee Gordon | CF | 31.110 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Dillon Maples | P | 27.093 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Steven Cishek | RP | 33.053 | Chicago Cubs | Chicago Cubs (MLB) | DL-10 Left hip inflammation |
| Keynan Middleton | RP | 25.332 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) for rehab |
| Jaime Barria | SP | 23.023 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Andrew Heaney | SP | 28.066 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Brock Stewart | SP | 27.312 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Lourdes Gurriel | 2B | 25.295 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Left quad strain |
| Noe Ramirez | RP | 29.231 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) for rehab |
| Jonathan Holder | RP | 26.062 | New York Yankees | New York Yankees (MLB) | DL-10 Right shoulder inflammation |
| Kyle Higashioka | C | 29.112 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Stephen Tarpley | P | 26.174 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Gary Sanchez | C | 26.251 | New York Yankees | New York Yankees (MLB) | Activated from DL |
| Dan Altavilla | RP | 26.336 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) for rehab |
| Johnathon Tripp | P | 25.077 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Ian Miller | OF | 27.171 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Ryan O'Rourke | P | 31.102 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Nick Vincent | P | 33.029 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Dylan Cozens | RF-OF | 25.071 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Tim Melville | P | 29.305 | Colorado Rockies | Albuquerque (AAA) | Placed on temporarily inactive list |
