| Julio Machado | 3B | 18.321 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Zach Guth | P | 22.117 | Colorado Rockies | Grand Junction (Rk) | Signed to Minor League Contract |
| Dwight Smith | OF | 26.277 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Left calf strain |
| Chandler Shepherd | P | 26.339 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Jose Rondon | SS | 25.149 | Baltimore Orioles | Baltimore Orioles (MLB) | Claimed off waivers from White Sox by Orioles |
| Ryan Lavarnway | C | 31.358 | Cincinnati Reds | Louisville (AAA) | Outrighted to minors |
| Spencer Turnbull | P | 26.315 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) for rehab |
| Jonathan Loaisiga | RP | 24.270 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) for rehab |
| Carson Fulmer | p | 25.229 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| David Phelps | RP | 32.294 | Chicago Cubs | Chicago Cubs (MLB) | Traded from Blue Jays to Cubs for Thomas Hatch |
| Thomas Hatch | P | 24.304 | Toronto Blue Jays | New Hampshire (AA) | Traded from Cubs to Blue Jays for David Phelps |
| Xavier Cedeno | P | 32.338 | Chicago Cubs | Chicago Cubs (MLB) | Transferred to 60-day DL |
| Jedd Gyorko | 3B-2B | 30.310 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Transferred to 60-day DL |
| Lane Thomas | OF | 23.342 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Adalberto Mejia | P | 26.040 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Claimed off waivers from Angels by Cardinals |
| Marcell Ozuna | LF | 28.260 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) for rehab |
| Geoff Hartlieb | P | 25.233 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Yefry Ramirez | P | 25.244 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Alex Mcrae | P | 26.115 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Montana Durapau | P | 27.125 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Jerad Eickhoff | SP | 29.028 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) for rehab |
| Marco Estrada | SP | 36.025 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) for rehab |
| Carlos Torres | P | 36.281 | | | Released by Twins |
| Kevin Cron | 1B | 26.163 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to AZL Diamondbacks (Rk) for rehab |
| Tony Gonsolin | P | 25.077 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Josh Sborz | P | 25.225 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Jake Rogers | C | 24.103 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Bobby Wilson | C | 36.113 | Detroit Tigers | Toledo (AAA) | Outrighted to minors |
| Dalton Pompey | CF | 26.231 | Toronto Blue Jays | Buffalo (AAA) | Outrighted to minors |
| Sean Reid-Foley | P | 23.335 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Christin Stewart | C-1B | 25.232 | Detroit Tigers | Detroit Tigers (MLB) | DL-7 Concussion |
| Victor Reyes | OF | 24.298 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Erich Weiss | 3B | 27.323 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Tyler Thornburg | CL | 30.304 | Los Angeles Dodgers | Oklahoma City (AAA) | Signed to Minor League Contract |
| Garrett Richards | SP | 31.064 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) for rehab |
| Pedro Strop | RP | 34.047 | Chicago Cubs | Chicago Cubs (MLB) | DL-10 Left neck tightness |
| Duane Underwood | P | 25.010 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Adam McCreery | P | 26.211 | Los Angeles Angels | Los Angeles Angels (MLB) | Designated for Assignment |
| J.C. Ramirez | SP | 30.348 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Blake Parker | P | 34.041 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Signed to 1-year contract for 2019-2019 ($0m) |
| Edgar Garcia | P | 22.299 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Mitchell Walding | SS | 26.323 | Philadelphia Phillies | Lehigh Valley (AAA) | Designated for Assignment |
| Ryan Pressly | RP | 30.227 | Houston Astros | Houston Astros (MLB) | DL-7 Right knee soreness |
| Daniel Robertson | 3B-SS | 25.130 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Justin Miller | P | 32.047 | Washington Nationals | Washington Nationals (MLB) | Designated for assignment |
| Chris Martin | RP | 33.058 | Atlanta Braves | Atlanta Braves (MLB) | Traded from rangers to Braves for Kolby Allard |
| Kolby Allard | RP | 21.351 | Texas Rangers | Nashville (AAA) | Traded from Braves to Rangers for Chris Martin |
| Kameron Misner | OF | 21.202 | Miami Marlins | Clinton (A) | Assigned to Clinton (A) |
| Mitchell Edwards | C | 19.364 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Julian Infante | IF | 22.309 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Joseph Monge | RF-OF | 24.073 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to Gulf Coast Red Sox (Rk) |
| Cole MacLaren | C | 22.050 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Brayan Mejia | P | 19.059 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Jimmy Robbins | P | 21.220 | Toronto Blue Jays | Bluefield (Rk) | Assigned to Bluefield (Rk) |
| Engel Estevez | P | 19.173 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Yennier Cano | P | 25.143 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Phil Capra | C-IF | 22.302 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Eduardo Salazar | OF | -- | New York Mets | Gulf Coast Mets (Rk) | Assigned to GCL Mets (Rk) |
| Richard Terrero | P | 21.324 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Reinstated to active roster |
| Douglas Lanza | C | 21.138 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Cody Reed | P | 23.053 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Brailin Pena | OF | 18.089 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Alexander Guerra | | -- | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Flemin Bautista | 2B | 19.142 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Bubba Derby | P | 25.156 | Milwaukee Brewers | Rocky Mountain (Rk) | Assigned to Rocky Mountain (Rk) |
| Zach Guth | P | 22.117 | Colorado Rockies | Grand Junction (Rk) | Assigned to Grand Junction (Rk) |
| Randy Pondler | P | 22.264 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Mason Fox | OF | 22.??? | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Juan Nunez | P | 23.189 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Chandler Avant | 2B | 24.019 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Harrison DiNicola | OF | 22.093 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Luis De Paula | P | 22.257 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Juan Aparicio | C | 19.065 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Michael Hernandez | C | 24.067 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Elih Marrero | C | 22.039 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Elvis Escobar | OF | 24.327 | Pittsburgh Pirates | West Virginia (A-) | Assigned to West Virginia (A-) |
| Michael Bienlien | P | 21.133 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Maddux Conger | P | 23.032 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Jeff Lindgren | P | 22.316 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Daniel Cody | P | 22.146 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Marcos Molina | P | 24.144 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Samuel Miranda | C | 21.343 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Kyle Marinconz | IF | 23.067 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Leemarcus Boyd | SS | 23.298 | Colorado Rockies | Lancaster (A+) | Assigned to Lancaster (A+) |
| Jack Perkins | P | 21.358 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Rafael Marchan | C | 20.155 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Nic Perkins | C | 23.162 | Washington Nationals | Hagerstown (A) | Activated from disabled list |
| Eric Gonzalez | C | 22.331 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Spencer Griffin | CF | 22.279 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Connor Scott | OF | 19.296 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Austin Dennis | IF | 22.205 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Gustavo Polanco | C | 22.047 | Chicago Cubs | South Bend (A) | Activated from disabled list |
| Omar Cruz | P | 20.185 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Joey Pulido | P | 23.309 | Toronto Blue Jays | Lansing (A) | DL-7 Injured |
| Zach Biermann | 1B | 22.058 | Houston Astros | Quad Cities (A) | DL-7 Injured |
| Justin Watts | P | 25.325 | Toronto Blue Jays | Lansing (A) | Activated from disabled list |
| Janson Junk | P | 23.197 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Jacob Zanon | CF | 24.035 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Jon Rosoff | UT | 24.258 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Lazaro Alonso | 1B | 24.225 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Victor Victor Mesa | OF | 23.010 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Mark Ecker | P | 24.064 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Jack Conley | C | 22.195 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Oneil Cruz | 3B | 20.299 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Chase Pinder | IF-OF | 23.136 | St. Louis Cardinals | Palm Beach (A+) | Activated from disabled list |
| Jake Thompson | P | 25.180 | Detroit Tigers | Lakeland (A+) | Reinstated to active roster |
| Daniel Amaral | OF | 22.145 | Pittsburgh Pirates | Bradenton (A+) | Activated from disabled list |
| David Masters | SS | 26.098 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Tyler Payne | C | 26.278 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Rodrigo Benoit | P | 25.157 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Kieran Lovegrove | P | 25.002 | Baltimore Orioles | Frederick (A+) | Activated from disabled list |
| Tyler Joyner | P | 23.081 | Baltimore Orioles | Frederick (A+) | DL-7 Injured |
| JP France | P | 24.117 | Houston Astros | Fayetteville (A+) | Placed on temporarily inactive list |
| Ricky Aracena | SS | 21.301 | Kansas City Royals | Wilmington (A+) | Activated from disabled list |
| Connor Kopach | IF | 24.360 | Seattle Mariners | Modesto (A+) | Assigned to Modesto (A+) |
| Casey Meisner | P | 24.069 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Sean Bouchard | 1B | 23.075 | Colorado Rockies | Lancaster (A+) | DL-7 Injured |
| Alberto Triunfel | SS | 25.179 | - | | Released by Springfield |
| Johan Mieses | OF | 24.017 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Nate Esposito | C | 26.035 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Jason Bahr | P | 24.165 | Texas Rangers | Frisco (AA) | Reinstated to active roster |
| Ronald Herrera | P | 24.088 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Mikey White | SS | 25.330 | Oakland Athletics | Midland (AA) | Activated from disabled list |
| Evan White | 1B-OF | 23.095 | Seattle Mariners | Arkansas (AA) | DL-7 Injured |
| Ian Rice | C | 25.345 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Reiver Sanmartin | P | 23.106 | Cincinnati Reds | Chattanooga (AA) | DL-7 Injured |
| Ryan Nutof | P | 23.271 | Cincinnati Reds | Chattanooga (AA) | Activated from disabled list |
| Chih-Wei Hu | P | 25.268 | - | | Released by Akron |
| Gift Ngoepe | SS | 29.193 | - | | Released by Altoona |
| Pedro Araujo | P | 26.028 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Drew Ward | 3B | 24.247 | Washington Nationals | Fresno (AAA) | Assigned to Fresno (AAA) |
| Kevin McGowan | P | 27.286 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Harol Gonzalez | P | 24.150 | New York Mets | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Jay Flaa | P | 27.050 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Tyler Erwin | P | 24.335 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Michael King | P | 24.066 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Kyle Dowdy | P | 26.177 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Jose Taveras | P | 25.266 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Quinn Brodey | P | 23.242 | New York Mets | Binghamton (AA) | Activated from disabled list |
| Nerluis Martinez | C | 23.111 | Philadelphia Phillies | Reading (AA) | DL-7 Injured |
| Anthony Gose | CF-OF | 28.354 | Cleveland Indians | Akron (AA) | Placed on temporarily inactive list |
| Kyle Nelson | P | 23.022 | Cleveland Indians | Akron (AA) | Activated from disabled list |
| Joshua Torres | P | 25.095 | New York Mets | Binghamton (AA) | Activated from disabled list |
| Bralin Jackson | OF | 25.240 | Pittsburgh Pirates | Altoona (AA) | DL-7 Injured |
| Jerrick Suiter | 1B-OF | 26.148 | Pittsburgh Pirates | Altoona (AA) | Activated from disabled list |
| Josh Tobias | SS | 26.249 | Boston Red Sox | Portland (AA) | DL-7 Injured |
| Hunter Cervenka | P | 29.208 | - | | Released by Cardinals |
| Jake Buchanan | P | 29.309 | - | | Released by Athletics |
| Mike Hauschild | P | 29.189 | - | | Released by Memphis |
| Tim Collins | P | 29.343 | - | | Elected Free Agency |
| Tyler Thornburg | P | 30.304 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Zac Rosscup | P | 31.051 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Nick Dini | UT | 26.003 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| Bengie Gonzalez | 3B-OF | 29.195 | Washington Nationals | Fresno (AAA) | DL-7 Injured |
| Luis Vasquez | P | 33.118 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Travis Snider | RF | 31.179 | Arizona Diamondbacks | Reno (AAA) | DL-7 Injured |
| Taylor Jones | P | 25.236 | Houston Astros | Round Rock (AAA) | Reinstated to active roster |
| Logan Morrison | 1B | 31.340 | Philadelphia Phillies | Lehigh Valley (AAA) | Activated from disabled list |
| Reymin Guduan | RP | 27.136 | Houston Astros | Round Rock (AAA) | Suspended for disciplinary reasons |
