| Rio Ruiz | 3B | 25.063 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Yency Almonte | RP | 25.050 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from Albuquerque (AAA) |
| Jose Cisnero | RP | 30.104 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Victor Alcantara | RP | 26.112 | Detroit Tigers | Detroit Tigers (MLB) | DL-10 Right middle finger contusion |
| Taylor Williams | P | 28.003 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from San Antonio (AAA) |
| Burch Smith | P | 29.103 | Milwaukee Brewers | San Antonio (AAA) | Assigned to San Antonio (AAA) |
| Adrian Sanchez | 2B | 28.342 | Washington Nationals | Washington Nationals (MLB) | Recalled from Harrisburg (AA) |
| Jonathan Holder | RP | 26.045 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Kyle Higashioka | C | 29.095 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Nestor Cortes | RP | 24.226 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Gary Sanchez | C | 26.234 | New York Yankees | New York Yankees (MLB) | DL-10 Left groin strain |
| Sean Rodriguez | LF | 34.089 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| David Peralta | RF | 31.345 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Ildemaro Vargas | SS | 28.008 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Addison Russell | SS | 25.182 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Brad Miller | SS | 29.279 | New York Yankees | New York Yankees (MLB) | DL-10 Right hip flexor strain |
| Willson Contreras | C | 27.072 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Tim Anderson | SS | 26.031 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) for rehab |
| Jake Junis | RP | 26.311 | Kansas City Royals | Kansas City Royals (MLB) | Placed on paternity leave list |
| Wily Peralta | P | 30.077 | | | Granted free agency |
| Jake Newberry | P | 24.246 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Shane Carle | RP | 27.329 | Atlanta Braves | Gwinnett (AAA) | Designated for Assignment |
| Wes Parsons | P | 26.321 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Jeremy Walker | P | 24.042 | Atlanta Braves | Atlanta Braves (MLB) | Contract purchased from minors |
| Francisco Cervelli | C | 33.140 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Transferred to 60-day DL |
| Clay Holmes | SP | 26.119 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-10 Right triceps inflammation |
| Blake Swihart | C | 27.112 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) for rehab |
| Carlos Torres | P | 36.275 | Minnesota Twins | Minnesota Twins (MLB) | Contract purchased from minors |
| Blake Parker | RP | 34.035 | Minnesota Twins | Minnesota Twins (MLB) | Designated for Assignment |
| Erick Fedde | SP | 26.149 | Washington Nationals | Fresno (AAA) | Assigned to Fresno (AAA) |
| Raudy Read | C | 25.268 | Washington Nationals | Washington Nationals (MLB) | Recalled from Fresno (AAA) |
| Devin Smeltzer | P | 23.321 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Daniel Stumpf | P | 28.201 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Jose Castillo | RP | 23.196 | San Diego Padres | Arizona Padres (Rk) | Assigned to AZL Padres (Rk) for rehab |
| Nick Hundley | C | 35.320 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL and DFA |
| Tanner Anderson | RP | 26.058 | Oakland Athletics | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Jimmy Nelson | SP | 30.049 | Milwaukee Brewers | San Antonio (AAA) | Assigned to San Antonio (AAA) for rehab |
| Kohl Stewart | P | 24.290 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Maddux Conger | P | 23.026 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Jose Chambuco | P | 17.026 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Keegan Fish | C | 19.309 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Luis Arcendo | SS | 19.266 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to Gulf Coast Rays (Rk) |
| Craig Lewis | OF | 22.063 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Jan Mercado | C | 19.331 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Shayne Fontana | CF | 22.033 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| James Ryan | P | 22.249 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Jherson Pereira | P | 22.178 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Adenys Bautista | P | 20.352 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| Mitchell Tyranski | P | 21.325 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Mason Thompson | P | 21.154 | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| Mitchell Stumpo | P | 23.037 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Eric Mock | P | 23.012 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Daniel Castro | 2B | 26.252 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Ricardo Hernandez | P | 21.170 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Wuilder Rodriguez | P | 26.184 | Milwaukee Brewers | Rocky Mountain (Rk) | Assigned to Rocky Mountain (Rk) |
| Ryan Halstead | P | 27.072 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Zach Watson | IF-OF | 22.029 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Dallas Litscher | P | 23.196 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Johnny Rizer | OF | 22.259 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Jerry Seitz | C | 24.300 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Keegan Curtis | P | 23.298 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Leonardo Taveras | P | 20.320 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Ryan Lidge | C | 24.270 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Will Robertson | OF | 24.144 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Reed Hayes | P | 24.129 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Robert Neustrom | OF | 22.254 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Jefry Valdez | P | 23.339 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Carlos Paraguate | SS | 18.172 | Atlanta Braves | Rome (A) | Activated from disabled list |
| Thomas St. Clair | P | 25.069 | - | | Released by Peoria |
| Imeldo Diaz | SS | 21.264 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Andres Matos | P | 23.133 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Connor Hollis | IF | 24.248 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Devin Conn | IF-OF | 22.112 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Bryce Nightengale | P | 22.342 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Payton Squier | 2B | 23.269 | Oakland Athletics | Beloit (A) | Activated from disabled list |
| Cobie Vance | 2B | 21.334 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Hugh Smith | P | 22.121 | Detroit Tigers | West Michigan (A) | DL-7 Injured |
| Russ Olive | 1B | 23.051 | Tampa Bay Rays | Bowling Green (A) | Activated from disabled list |
| RJ Freure | P | 22.018 | Houston Astros | Quad Cities (A) | Placed on temporarily inactive list |
| Orlando Romero | P | 22.301 | - | | Released by Charlotte |
| Nick Neidert | P | 22.246 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Michael Perri | P | 23.323 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Stephen Woods | P | 24.044 | Tampa Bay Rays | Charlotte (A+) | DL-7 Injured |
| Trevor Craport | 3B | 22.346 | - | | Released by Frederick |
| Cameron Ming | P | 23.083 | - | | Released by Frederick |
| Kirvin Moesquit | SS | 24.136 | - | | Released by Frederick |
| Yapson Gomez | P | 25.295 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Kirk McCarty | P-OF | 23.286 | Cleveland Indians | Lynchburg (A+) | Activated from disabled list |
| Riley Echols | P | 24.103 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Dakody Clemmer | OF | 23.187 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Tyler Carpenter | P | 27.150 | Los Angeles Angels | Mobile (AA) | Assigned to Mobile (AA) |
| Steve Berman | C | 24.238 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Aaron Hernandez | P | 22.234 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| James Naile | P | 26.166 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Kazuhisa Makita | P | 34.256 | San Diego Padres | Amarillo (AA) | Assigned to Amarillo (AA) |
| Brian Howard | P | 24.090 | Oakland Athletics | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Rocky Gale | C | 31.153 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Conner Capel | OF | 22.066 | St. Louis Cardinals | Springfield (AA) | Activated from disabled list |
| Jeff Kinley | P-OF | 27.160 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Zack Kelly | P | 24.143 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Brett Graves | P | 26.175 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Francisco Arcia | C | 29.313 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Henry Martinez | P | 25.088 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Adonis Rosa | P | 24.249 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Jerry Downs | OF | 25.214 | Boston Red Sox | Portland (AA) | DL-7 Injured |
| Ryder Ryan | P | 24.074 | New York Mets | Binghamton (AA) | Reinstated to active roster |
| Josh Tobias | SS | 26.243 | Boston Red Sox | Portland (AA) | Activated from disabled list |
| Jett Bandy | C | 29.120 | Texas Rangers | Nashville (AAA) | Reinstated to active roster |
| Sean Murphy | C | 24.293 | Oakland Athletics | Las Vegas (AAA) | Activated from disabled list |
| Cody Allen | P | 30.246 | Minnesota Twins | Rochester (AAA) | Placed on temporarily inactive list |
| Logan Morrison | 1B | 31.334 | Philadelphia Phillies | Lehigh Valley (AAA) | DL-7 Injured |
| James Karinchak | P | 23.306 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Michael McAvene | P | 21.334 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Forrest Whitley | P | 21.312 | Houston Astros | Fayetteville (A+) | Assigned to Fayetteville (A+) |
| Enoli Paredes | P | 23.300 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
