| Cody Anderson | RP | 28.222 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Jefry Rodriguez | p | 25.272 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Austin Pruitt | RP | 29.236 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Blake Snell | SP | 26.141 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Activated from DL |
| Jonathan Davis | CF | 26.347 | Toronto Blue Jays | Buffalo (AAA) | Activated from DL and assigned to Buffalo (AAA) |
| Jake Cave | CF | 26.138 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Tyler Duffey | RP | 28.118 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Kohl Stewart | P | 24.199 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Fernando Romero | P | 24.121 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Justin Miller | P | 31.316 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) for rehab |
| Luke Gregerson | RP | 34.345 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) for rehab |
| Hunter Wood | P | 25.255 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Reinstated to active roster |
| Ji-Man Choi | 1B | 27.341 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Reinstated to active roster |
| Andrew Velazquez | SS | 24.284 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Harrison Bader | CF | 24.325 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Activated from DL |
| Daniel Poncedeleon | P | 27.099 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Daniel Murphy | 2B | 34.023 | Colorado Rockies | Colorado Rockies (MLB) | Activated from DL |
| Jeff Hoffman | SP | 26.106 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Zac Reininger | P | 26.086 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Ryne Ogren | IF | 22.013 | Baltimore Orioles | Aberdeen (A-) | Traded from Mariners to Orioles for Mike Wright |
| Chad Green | RP | 27.336 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Kyle Higashioka | C | 29.004 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Stephen Tarpley | P | 26.066 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Gary Sanchez | C | 26.143 | New York Yankees | New York Yankees (MLB) | Activated from DL |
| Gabriel Moya | P | 24.105 | Minnesota Twins | Rochester (AAA) | Activated from DL and assigned to Rochester (AAA) |
| Bobby Poyner | p | 26.144 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Darwinzon Hernandez | P | 22.128 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Jose Pirela | 2B | 29.154 | San Diego Padres | San Diego Padres (MLB) | DL-10 Strained left oblique |
| Ty France | IF | 24.285 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Mitchell Walding | SS | 26.226 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Drew Anderson | RP | 25.033 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| David Bote | 3B | 26.017 | Chicago Cubs | Chicago Cubs (MLB) | Reinstated to active roster |
| Alec Mills | RP | 27.146 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| James Pazos | RP | 27.355 | Philadelphia Phillies | Lehigh Valley (AAA) | Designated for Assignment |
| Sean Rodriguez | LF | 33.363 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Enyel De Los Santos | p | 23.121 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Josh Lucas | P | 28.170 | Baltimore Orioles | Norfolk (AAA) | Outrighted to minors |
| Sam Freeman | P | 31.305 | Los Angeles Angels | Los Angeles Angels (MLB) | Designated for Assignment |
| Tim Hill | P | 29.073 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Matt Ramsey | P | 29.212 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from minors |
| Rougned Odor | 2B | 25.080 | Texas Rangers | Nashville (AAA) | Assigned to Nashville (AAA) for rehab |
| Brian Flynn | RP | 29.005 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) for rehab |
| Gabriel Noguera | P | 22.328 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Jonathan Dziedzic | P | 28.079 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Matt Pidich | P | 24.120 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Ricky Salinas | P | 23.029 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Allan Winans | P | 23.258 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Jacob Blank | P | 23.068 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Adrian Rodriguez | P | 22.259 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Sal Giardina | C | 26.359 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| James McArthur | P | 22.134 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Ryne Ogren | IF | 22.013 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Scott Burke | P | 24.326 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Jacob Billingsley | P | 24.271 | Houston Astros | Fayetteville (A+) | Assigned to Fayetteville (A+) |
| Kevin Gowdy | P | 21.159 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Francisco Morales | P | 19.180 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Victor Santos | P | 18.286 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Bryce Conley | P | 24.245 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Matt Solter | P | 25.324 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Jaison Vilera | P | 21.309 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Connor Hoover | SS | 22.280 | Seattle Mariners | West Virginia (A) | Assigned to West Virginia (A) |
| Jasseel De la Cruz | P | 21.302 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Josh Stowers | OF | 22.058 | New York Yankees | Charleston (sc) (A) | DL-7 Injured |
| Brett Daniels | P | 23.059 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Willy Collado | P | 21.025 | Houston Astros | Fayetteville (A+) | Assigned to Fayetteville (A+) |
| Alexis Wilson | C | 22.254 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Joey Gonzalez | P-IF | 22.104 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Joe Cronin | P-IF | 24.344 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Andrew Cabezas | P | 22.140 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Michael Davis | 3B | 23.093 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Jacob Heatherly | P | 20.339 | Cincinnati Reds | Dayton (A) | DL-7 Injured |
| Mark Moclair | P | 22.042 | Houston Astros | Quad Cities (A) | DL-7 Injured |
| Lester Madden | OF | 20.095 | Oakland Athletics | Beloit (A) | Activated from disabled list |
| Jon Kennedy | P | 23.217 | - | | Released by Florida |
| Anthony Bemboom | C | 29.096 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Dennis Ortega | C | 21.317 | St. Louis Cardinals | Palm Beach (A+) | Activated from disabled list |
| Edward Cabrera | P | 21.011 | Miami Marlins | Jupiter (A+) | Activated from disabled list |
| Jonathan Ortega | IF | 22.209 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Carlos Sanabria | P | 22.090 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Aramis Ademan | SS | 20.223 | Chicago Cubs | Myrtle Beach (A+) | Reinstated to active roster |
| Diogenes Almengo | P | 23.327 | Baltimore Orioles | Frederick (A+) | Reinstated to active roster |
| Jake Thompson | P | 24.214 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Danny Garcia | P | 25.062 | - | | Released by Modesto |
| Matt Walker | P | 24.208 | Seattle Mariners | Modesto (A+) | Assigned to Modesto (A+) |
| Kevin McCanna | P | 25.082 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Joel Seddon | P | 26.285 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| David MacKinnon | P | 24.130 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Zachary Lovvorn | P | 24.333 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Evan White | 1B-OF | 22.363 | Seattle Mariners | Arkansas (AA) | Activated from disabled list |
| Daniel Camarena | P | 26.166 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Adrian Almeida | P | 24.058 | Los Angeles Angels | Mobile (AA) | Assigned to Mobile (AA) |
| Drew Maggi | OF-SS | 29.343 | Milwaukee Brewers | Pensacola (AA) | Assigned to Pensacola (AA) |
| Ramon Torres | SS-2B | 26.092 | Chicago White Sox | Birmingham (AA) | Placed on temporarily inactive list |
| Craig Brooks | P | 26.213 | Chicago Cubs | Tennessee (AA) | Reinstated to active roster |
| Teddy Stankiewicz | P | 25.150 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Jake Romanski | C | 28.123 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Nick Lovullo | SS | 25.144 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Spenser Watkins | P | 26.240 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Matthew Gorst | P | 24.243 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Oscar Hernandez | C | 25.289 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Jake Paulson | P | 27.067 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| John Schreiber | P | 25.050 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Kevin Lenik | P | 27.267 | - | | Released by Omaha |
| Zach Borenstein | OF | 28.275 | - | | Released by Iowa |
| Tyler Cloyd | P | 31.344 | Seattle Mariners | Tacoma (AAA) | |
| Taylor Guerrieri | P | 26.144 | Texas Rangers | Nashville (AAA) | DL-7 Injured |
| Mike Kaelin | P | 25.025 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Eduardo Paredes | P | 24.049 | - | | Released by Toledo |
| Chad De La Guerra | IF | 26.151 | Boston Red Sox | Pawtucket (AAA) | Activated from disabled list |
| Dan Runzler | P | 34.025 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Pedro Florimon | SS | 32.135 | Atlanta Braves | Gwinnett (AAA) | Placed on temporarily inactive list |
| Bo Bichette | SS | 21.050 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Spencer Kulman | P | 24.026 | - | | Announced retirement |
| Wladimir Galindo | 3B | 22.169 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Mike Wright | SP | 29.111 | Seattle Mariners | Seattle Mariners (MLB) | Traded from Orioles to Mariners for Ryne Ogren |
| Zack Cozart | 2B | 33.255 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-10 Neck strain |
