| Oliver Drake | RP | 31.202 | Minnesota Twins | Minnesota Twins (MLB) | Claimed off waivers from Blue Jays by Twins |
| Matt Magill | RP | 28.266 | Minnesota Twins | Minnesota Twins (MLB) | Placed on paternity leave list |
| A.J. Schugel | RP | 29.037 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) for rehab |
| Dylan Tice | 2b | 25.231 | New York Mets | New York Mets (MLB) | Signed to Minor League Contract |
| Juan Nicasio | RP | 31.337 | Seattle Mariners | Seattle Mariners (MLB) | DL-10 Right knee inflammation |
| Chasen Bradford | RP | 28.363 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Tyler Lyons | RP | 30.164 | St. Louis Cardinals | Memphis (AAA) | Outrighted to minors |
| Cionel Perez | p | 22.104 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Chris Devenski | RP | 27.263 | Houston Astros | Houston Astros (MLB) | DL-10 Left hamstring tightness |
| Chris Rusin | RP | 31.285 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) for rehab |
| Sebastian Kessay | P | 25.045 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Signed to Minor League Contract |
| Erik Goeddel | RP | 29.226 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Right lat inflammation |
| Brandon Cumpton | P | 29.260 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Kevin Pillar | CF | 29.211 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Christian Binford | P | 25.226 | Detroit Tigers | Erie (AA) | Traded from Orioles to Tigers for cash |
| Dovydas Neverauskas | P | 25.201 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Steven Brault | RP | 26.096 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Cesar Puello | OF | 27.124 | San Francisco Giants | San Francisco Giants (MLB) | Signed to Minor League Contract |
| Chris Owings | SS-RF | 26.357 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Andrew Chafin | RP | 28.047 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Reinstated to active roster |
| Jhan Marinez | P | 29.356 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Right hamstring strain |
| Jesus Reyes | p | 25.163 | Cincinnati Reds | Cincinnati Reds (MLB) | Recalled from Louisville (AAA) |
| Blake Swihart | C | 26.122 | Boston Red Sox | Boston Red Sox (MLB) | DL-10 Right hamstring strain |
| Daniel Butler | C | 31.290 | Boston Red Sox | Boston Red Sox (MLB) | Contract purchased from minors |
| Evan Marshall | P | 28.107 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) for rehab |
| Josh Tomlin | SP | 33.288 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) for rehab |
| Tommy Pham | LF | 30.148 | Tampa Bay Rays | Tampa Bay Rays (MLB) | DL-10 Right foot fracture |
| Adam Kolarek | P | 29.201 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Steven Matz | SP | 27.066 | New York Mets | New York Mets (MLB) | DL-10 Flexor pronator strain in left arm |
| Corey Oswalt | P | 24.334 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Tom Kahnle | RP | 28.361 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Luis Cessa | SP | 26.100 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Dustin Garneau | C | 30.356 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Kevan Smith | C | 30.036 | Chicago White Sox | Chicago White Sox (MLB) | Placed on the paternity leave list |
| Johnny Field | OF | 26.165 | Minnesota Twins | Rochester (AAA) | Claimed off waivers from Indians by Twins and assigned to Rochester (AAA) |
| Carlos Ramirez | OF | 27.101 | Oakland Athletics | Nashville (AAA) | Outrighted to minors |
| Ramon Laureano | CF | 24.019 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Andrew Miller | RP | 33.074 | Cleveland Indians | Cleveland Indians (MLB) | Activated from DL |
| Zach McAllister | RP | 30.239 | Cleveland Indians | Cleveland Indians (MLB) | Designated for Assignment |
| Tyler Mahle | P | 23.308 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Randy Rosario | P | 24.077 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Brian Duensing | RP | 35.162 | Chicago Cubs | Chicago Cubs (MLB) | DL-10 Left shoulder inflammation |
| Evan Phillips | p | 23.326 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Jake Holmes | SS | 20.032 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Zach Schellenger | P | 22.207 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to Gulf Coast Red Sox (Rk) |
| Eric Hanhold | P | 24.275 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Saul Torres | C | 19.165 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Wilmer Reyes | SS | 20.224 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Carlos Sierra | P | 23.289 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Eric Sogard | 2B | 32.073 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Danny Hultzen | P | 28.248 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Daulton Varsho | C | 22.032 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Matt Holliday | LF | 38.215 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Robert Garcia | P | 22.050 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Adalberto Pena | P | 23.145 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Mark Washington | P | 22.134 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Stephen Keller | P | 20.257 | Houston Astros | Greeneville (Rk) | |
| Luis Oviedo | P | 19.080 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Gian Paul Gonzalez | C | 22.205 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Jean Carmona | SS | 18.277 | Baltimore Orioles | Aberdeen (A-) | |
| Yeizo Campos | P | 22.096 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Trent Johnson | P | 21.356 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Dylan Tice | 2B | 25.231 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Jean Carlos Encarnacion | 3B | 20.198 | Baltimore Orioles | Delmarva (A) | |
| Holden Capps | P | 23.132 | Kansas City Royals | Lexington (A) | DL-7 Injured |
| Daniel Brito | SS | 20.192 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Eduard Conde | SS | 20.171 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Jagger Rusconi | OF | 22.016 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Jesse Berardi | SS | 22.203 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Willis Montgomerie | P | 23.062 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Sven Schueller | P | 22.199 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Juliandry Higuera | P | 23.331 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Raphael Gladu | OF | 23.041 | New York Mets | St. Lucie (A+) | DL-7 Injured |
| Jose Pujols | RF-OF | 22.309 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Morgan Lofstrom | C | 22.352 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Blake Bivens | P | 22.358 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Jesus Sanchez | OF | 20.300 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Nick Hartman | P | 23.283 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Roldani Baldwin | C | 22.140 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Erlin Cerda | 2B | 24.090 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Bobby Dalbec | IF | 23.035 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Jake Cosart | P | 24.173 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Matt Peacock | P | 24.157 | Arizona Diamondbacks | Visalia (A+) | DL-7 Injured |
| Joey Marciano | P | 23.204 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Hansel Rodriguez | P | 21.157 | San Diego Padres | Lake Elsinore (A+) | Activated from disabled list |
| Dominic Miroglio | C | 23.146 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| Colby Blueberg | P | 25.084 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Sebastian Kessay | P | 25.045 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Yonathan Mendoza | 3B-SS | 24.174 | Seattle Mariners | Arkansas (AA) | Activated from disabled list |
| Khalil Lee | OF | 20.038 | Kansas City Royals | Northwest Arkansas (AA) | DL-7 Injured |
| Taylor Hearn | P | 23.338 | Texas Rangers | Frisco (AA) | |
| Tyler Higgins | P | 27.103 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Alfredo Escalera-Maldonado | OF | 23.167 | Kansas City Royals | Northwest Arkansas (AA) | Activated from disabled list |
| Craig Brooks | P | 25.314 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Dan Robertson | OF | 32.307 | - | | Released by Diamondbacks |
| Christian Binford | P | 25.226 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Mark Ecker | P | 23.068 | Detroit Tigers | Erie (AA) | DL-7 Injured |
| Pat Ruotolo | P | 23.200 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Jiandido Tromp | OF | 24.310 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Alexis Rivero | P | 23.289 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Ranfi Casimiro | P | 26.018 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Charlie Madden | C | 22.337 | Boston Red Sox | Portland (AA) | DL-7 Injured |
| Mike Shawaryn | P | 23.320 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Luis Ortiz | P | 22.316 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Josh Ockimey | 1B | 22.290 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| David Sosebee | P | 24.343 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Parker Morin | C | 27.032 | Kansas City Royals | Omaha (AAA) | Placed on temporarily inactive list |
| Richelson Pena | P | 24.308 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Elliot Soto | SS | 28.347 | Colorado Rockies | Albuquerque (AAA) | DL-7 Injured |
| Scott Heineman | OF | 25.242 | Texas Rangers | Round Rock (AAA) | Activated from disabled list |
| Cesar Puello | OF | 27.124 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Dario Alvarez | P | 29.198 | - | | Released by Mariners |
| Austin House | P | 27.191 | - | | Released by Rockies |
| Shawn O'Malley | SS | 30.219 | Colorado Rockies | Albuquerque (AAA) | Placed on temporarily inactive list |
| D.J. Baxendale | P | 27.238 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Matt McBride | C | 33.072 | Philadelphia Phillies | Lehigh Valley (AAA) | Activated from disabled list |
| Juan Graterol | C | 29.170 | Minnesota Twins | Rochester (AAA) | Activated from disabled list |
| Nick Rickles | C | 28.182 | Philadelphia Phillies | Lehigh Valley (AAA) | DL-7 Injured |
| Tom Windle | P | 26.146 | Philadelphia Phillies | Lehigh Valley (AAA) | Placed on temporarily inactive list |
| Tim Federowicz | C | 30.364 | Cincinnati Reds | Louisville (AAA) | Signed to Minor League Contract |
| Adron Chambers | OF | 31.299 | - | | Released by Phillies |
| Edisson Gonzalez | SS | 18.110 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Gabriel Moreno | C | 18.171 | Toronto Blue Jays | Bluefield (Rk) | Assigned to Bluefield (Rk) |
| Jhon Torres | OF | 18.127 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | |
| Francis Beriguete | P | 18.358 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Travis Perry | P | 21.148 | San Francisco Giants | Arizona Giants Orange (Rk) | Assigned to Arizona Giants Orange (Rk) |
| Ezequiel Pagan | CF | 18.026 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Bryce Bush | 3B | 18.233 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| Jimmy Galusky | IF | 22.097 | Chicago White Sox | Arizona White Sox (Rk) | Assigned to Arizona White Sox (Rk) |
| Luis Rodriguez | SS | 19.154 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Cody Eckerson | P | 23.162 | Los Angeles Angels | Arizona Angels (Rk) | Assigned to Arizona Angels (Rk) |
| Justin Garcia | P | 23.032 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Cristofer Ogando | P | 24.284 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Andrew Mitchell | P | 23.284 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Robert Boselli | C | 22.108 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Matt Sanders | IF | 22.057 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Vinny Capra | SS | 22.027 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Madison Stokes | SS | 22.100 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Richie Palacios | IF | 21.079 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Samir Vivas | P | 23.183 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Juremi Profar | SS | 22.186 | Texas Rangers | Frisco (AA) | |
| Adam Hofacket | P | 24.166 | Los Angeles Angels | Mobile (AA) | DL-7 Injured |
| Jason Alexander | P | 25.155 | Los Angeles Angels | Mobile (AA) | Reinstated to active roster |
| Cesar Loaiza | P | 20.024 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Carlos Ventura | P | 21.032 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Peter Bayer | P | 24.150 | Oakland Athletics | Arizona Athletics (Rk) | Assigned to Arizona Athletics (Rk) |
| Reilly Johnson | C | 21.311 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
