| Zac Rosscup | RP | 30.032 | Los Angeles Dodgers | Oklahoma City (AAA) | Claimed off waivers from Rockies by Dodgers and assigned to Oklahoma City (AAA) |
| Jeanmar Gomez | RP | 29.282 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Garrett Richards | SP | 30.045 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-10 Right elbow UCL damage |
| Marcos Molina | P | 23.125 | | | Released by Mets |
| Edward Paredes | P | 31.284 | Los Angeles Dodgers | Oklahoma City (AAA) | Designated for Assignment |
| Victor Alcantara | RP | 25.099 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Jerry Vasto | P | 26.150 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Bryan Shaw | RP | 30.246 | Colorado Rockies | Colorado Rockies (MLB) | Activated from DL |
| Vincent Velasquez | SP | 26.034 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Enyel De Los Santos | p | 22.199 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| David Bote | 3B | 25.095 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Tyler Lyons | RP | 30.141 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) for rehab |
| Andrew Cashner | SP | 31.303 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Neck strain |
| Yefry Ramirez | P | 24.225 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Cionel Perez | p | 22.081 | Houston Astros | Houston Astros (MLB) | Recalled from Corpus Christi (AA) |
| Ken Giles | RP | 27.294 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Tyler Olson | P | 28.282 | Cleveland Indians | Cleveland Indians (MLB) | Activated from DL |
| Marc Rzepczynski | P | 32.337 | Cleveland Indians | Cleveland Indians (MLB) | Designated for Assignment |
| Kevin Kaczmarski | OF | 26.193 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Drew Gagnon | P | 28.015 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Jacob Rhame | P | 25.117 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Ryan Williamson | P | 23.074 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Chaz Hebert | P | 25.310 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Christin Stewart | C-1B | 24.213 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Connor Jones | P | 23.236 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Austen Wade | OF | 22.145 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| Harrison Wenson | C | 23.081 | Los Angeles Angels | Arizona Angels (Rk) | Assigned to Arizona Angels (Rk) |
| Chester Pimentel | P | 22.242 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Yeison Cespedes | P | 20.128 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Connor Bennett | P | 21.092 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Henry Owens | P | 25.355 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| A.J. Kennedy | C | 24.169 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Jansiel Rivera | CF | 19.317 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Joey Marciano | P | 23.181 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Angel Rondon | P | 20.222 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Andrew Gist | P | 23.105 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Jordan Kipper | P | 25.278 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Durin O'Linger | P | 24.274 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Malcolm Seibert | 2B | 24.236 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Gian Paul Gonzalez | C | 22.182 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Franyel Casadilla | P | 21.097 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Connor Zwetsch | P | 23.066 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Keith Skinner | C | 24.088 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Raphael Gladu | OF | 23.018 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Brandon Boggetto | SS | 24.243 | - | | Released by Nationals |
| Kevin Marnon | P | 24.117 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Bowden Francis | P | 22.080 | Milwaukee Brewers | Wisconsin (A) | Reinstated to active roster |
| Ulysses Cantu | 3B | 20.071 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Kyle Nelson | P | 22.003 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Jesus Cruz | P | 23.087 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Robbie Gordon | P | 25.033 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Cole Stapler | P | 23.201 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Jovani Moran | P | 21.078 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Jay Feliciano | PF | 22.287 | Milwaukee Brewers | Wisconsin (A) | DL-7 Injured |
| Brady Anderson | IF-P | 25.243 | - | | Released by Twins |
| Chase Mullins | P | 23.357 | Atlanta Braves | Florida (A+) | Activated from disabled list |
| Ian Strom | CF | 23.211 | New York Mets | St. Lucie (A+) | DL-7 Injured |
| Angel Aguilar | SS | 23.028 | New York Yankees | Tampa (A+) | Activated from disabled list |
| Steven Sensley | OF | 22.309 | New York Yankees | Tampa (A+) | DL-7 Injured |
| Mitch Keller | P | 22.098 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Junior Fernandez | P | 21.131 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Estarlin Arias | P | 24.050 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Mauricio Cabrera | P | 24.292 | - | | Released by Braves |
| Jason Bahr | P | 23.146 | Texas Rangers | Down East (A+) | Assigned to Down East (A+) |
| Joan Martinez | P | 21.316 | Boston Red Sox | Salem (A+) | Activated from disabled list |
| Carlos Tovar | SS | 22.326 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Tyler Ferguson | P | 24.279 | Texas Rangers | Down East (A+) | DL-7 Injured |
| P.J. Higgins | IF | 25.062 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Tanner Banks | P | 26.261 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Hector Perez | P | 22.035 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Connor Overton | P | 24.352 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Isaac Anderson | P | 24.310 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Imani Abdullah | P | 21.082 | - | | Announced retirement |
| Erik Johnson | P | 28.193 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Chris Chinea | C | 24.069 | St. Louis Cardinals | Springfield (AA) | DL-7 Injured |
| Johnny Fasola | P | 26.212 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Carmen Benedetti | IF | 23.255 | Houston Astros | Corpus Christi (AA) | Activated from disabled list |
| Carlos Sierra | P | 23.266 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Jose Cardona | OF | 24.117 | Texas Rangers | Frisco (AA) | Activated from disabled list |
| Jacob Nix | P | 22.184 | San Diego Padres | San Antonio (AA) | Activated from disabled list |
| Shea Spitzbarth | P | 23.280 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Forrest Whitley | P | 20.299 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Will Remillard | C | 25.296 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jeffrey Baez | OF | 24.254 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Luis Marte | SS | 24.208 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Cameron Rupp | C | 29.286 | - | | Released by Twins |
| Matt Den Dekker | CF-OF | 30.336 | New York Mets | New York Mets (MLB) | Contract purchased from minors |
| Jalen Beeks | RP | 25.001 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Robby Scott | RP | 28.316 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Kris Bryant | 3B | 26.189 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Ian Kennedy | SP | 33.204 | Kansas City Royals | Kansas City Royals (MLB) | DL-10 Left oblique strain |
| Austin Jackson | CF | 31.160 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| Jason Adam | RP | 26.342 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Addison Reed | CL | 29.196 | Minnesota Twins | Minnesota Twins (MLB) | DL-10 Right trieps tendinitis |
| Alan Busenitz | RP | 27.323 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Jose Alvarado | CL | 23.051 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Placed on family medical emergency leave list |
| Andrew Kittredge | P | 28.116 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Deck McGuire | P | 29.018 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Bruce Rondon | RP | 27.214 | Chicago White Sox | Chicago White Sox (MLB) | Designated for Assignment |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Trent Woodward | C | 26.158 | - | | Announced retirement |
| Ivan DeJesus | 2B | 31.071 | Boston Red Sox | Pawtucket (AAA) | Placed on temporarily inactive list |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Trent Woodward | C | 26.158 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Matt Albanese | OF-P | 22.351 | - | | Announced retirement |
| Tre Todd | C | 21.285 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Tanner Chock | P | 21.337 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Carlos Rodriguez | C | 19.121 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Zach Rheams | 1B | 22.006 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Tyler Webb | SS | 22.087 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Daniel Lynch | P | 21.236 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Michael Helman | IF | 22.049 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Jack Thoreson | C | 23.016 | Seattle Mariners | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Kyler Stout | P | 23.271 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Nico Hoerner | SS | 21.059 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Riley Thompson | P | 22.002 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Orleny Quiroz | P | 24.355 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Clayton Daniel | IF | 23.062 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Nick Sprengel | P | 21.037 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Madison Stokes | SS | 22.077 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| J.P. France | P | 23.098 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Anderson Bohorquez | SS | 20.281 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Clark Brinkman | CF | 22.127 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Ryan Walker | P | 22.228 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Fidel Castro | OF | 19.197 | Cincinnati Reds | Arizona Reds (Rk) | Assigned to Arizona Reds (Rk) |
| Felix Minjarez | | -- | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| Felix Jorge | P | 24.190 | Minnesota Twins | Chattanooga (AA) | Signed to Minor League Contract |
