| Jose Azocar | OF | 22.048 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Matt Manning | P | 20.151 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Cam Gibson | OF | 24.136 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Jacob Robson | OF | 23.220 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Steve Pearce | LF | 35.076 | Boston Red Sox | Boston Red Sox (MLB) | Traded from Blue Jays to Red Sox for Santiago Espinal |
| Santiago Espinal | SS | 23.227 | Toronto Blue Jays | Dunedin (A+) | Traded from Red Sox to Blue Jays for Steve Pearce |
| Nik Turley | P | 28.290 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-60 Injured |
| Jorge Bonifacio | RF | 25.024 | Kansas City Royals | Kansas City Royals (MLB) | Reinstated to active roster |
| Sandy Alcantara | SP | 22.295 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Nick Wittgren | RP | 27.030 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Carlos Perez | C | 27.244 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) for rehab |
| Ronald Acuna | LF | 20.192 | Atlanta Braves | Atlanta Braves (MLB) | Activated from DL |
| Matt Wisler | SP | 25.289 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Wes Parsons | P | 25.295 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Brandon McCarthy | SP | 34.357 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Right knee tendinitis |
| Taylor Cole | P | 28.312 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from minors |
| Eduardo Paredes | P | 23.114 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Nolan Fontana | IF | 27.022 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Zack Cozart | 2B | 32.320 | Los Angeles Angels | Los Angeles Angels (MLB) | Transferred to 60-day DL |
| Jake Jewell | P | 25.043 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-10 Right fibula fracture |
| Adrian Houser | RP | 25.146 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Mike Zagurski | RP | 35.152 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Contract purchased from minors |
| Yuli Gurriel | 1B | 34.019 | Houston Astros | Houston Astros (MLB) | Placed on paternity leave list |
| Juan Graterol | C | 29.134 | Minnesota Twins | Minnesota Twins (MLB) | Signed to Minor League Contract |
| A.J. Reed | 1B | 25.049 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Joshua Fields | RP | 32.313 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Right shoulder inflammation |
| Mitch Hansen | OF | 22.058 | New York Yankees | New York Yankees (MLB) | Signed to Minor League Contract |
| Donnie Hart | RP | 27.295 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Yefry Ramirez | P | 24.212 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Chance Sisco | C | 23.124 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Tyler Chatwood | SP | 28.194 | Chicago Cubs | Chicago Cubs (MLB) | Reinstated from paternity leave list |
| Dillon Maples | P | 26.050 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Ryan Goins | 3B-2B | 30.136 | Kansas City Royals | Kansas City Royals (MLB) | Designated for Assignment |
| Cameron Knight | C | 23.225 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Clarke Schmidt | P | 22.129 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Anton Kuznetsov | P | 20.033 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Denny Martinez | P | 21.239 | Philadelphia Phillies | Gulf Coast Phillies West (Rk) | Assigned to Gulf Coast Phillies West (Rk) |
| Jesus Azuaje | SS | 20.321 | Philadelphia Phillies | Gulf Coast Phillies West (Rk) | Assigned to Gulf Coast Phillies West (Rk) |
| Matthew Foley | C | 24.074 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Jared Akins | OF | 21.198 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Charlie Neuweiler | P | 19.140 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Freddy Rodriguez | OF | 21.225 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Harrison White | IF | 23.222 | - | | Released by Marlins |
| Cooper Goldby | C | 23.161 | Oakland Athletics | Vermont (A-) | DL-7 Injured |
| Billy Lescher | P | 22.285 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Alexis Wilson | C | 21.319 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Jeremiah McCray | OF | 20.117 | - | | Released by A's |
| Doug Domnarski | P | 23.355 | - | | Released by Marlins |
| Logan Boyd | P | 24.214 | - | | Released by Marlins |
| Ramon Rosso | P | 22.019 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Jeyner Baez | C | 22.339 | Washington Nationals | Hagerstown (A) | DL-7 Injured |
| Alex Dunlap | OF | 23.265 | Washington Nationals | Hagerstown (A) | Activated from disabled list |
| Bruce Zimmermann | P | 23.139 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Mitch Hansen | OF | 22.058 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Ismael Cabrera | P | 24.009 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Garrett Hope | C | 24.183 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Robert Molina | C | 21.285 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Dennis Ortega | C | 21.017 | St. Louis Cardinals | Peoria (A) | DL-7 Injured |
| Lane Ratliff | P | 23.098 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Tyler Watson | P | 21.037 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| John Sansone | SS | 24.286 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Jesse Adams | P-OF | 24.320 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Brusdar Graterol | P | 19.306 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Matt Morgan | C | 22.153 | - | | Released by Blue Jays |
| Alberti Chavez | 2B-3B | 22.343 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Brian Trieglaff | P | 24.015 | New York Yankees | Tampa (A+) | DL-7 Injured |
| Will Carter | P | 25.161 | New York Yankees | Tampa (A+) | DL-7 Injured |
| Hector Vargas | SS | 23.152 | Cincinnati Reds | Daytona (A+) | DL-7 Injured |
| Kevin Canelon | P | 24.163 | Cincinnati Reds | Daytona (A+) | Activated from disabled list |
| Johan Mieses | OF | 22.351 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Alejandro Salazar | SS | 21.266 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Jake Fishman | P | 23.140 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Santiago Espinal | SS | 23.227 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Mitch Nay | 3B | 24.281 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Stefan Trosclair | 2B | 23.340 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Kenny Wilson | OF | 28.149 | - | | Released by Tigers |
| Francisco Jimenez | P | 23.267 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Brandon Bielak | P | 22.087 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Arnaldo Hernandez | P | 22.140 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| John Nogowski | OF-1B | 25.174 | St. Louis Cardinals | Springfield (AA) | Activated from disabled list |
| Anthony Misiewicz | P | 23.239 | Seattle Mariners | Arkansas (AA) | Activated from disabled list |
| Nicky Lopez | SS | 23.107 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Taylor Jones | P | 24.204 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Zach Houchins | SS | 25.285 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Zander Wiel | IF | 25.168 | Minnesota Twins | Chattanooga (AA) | Activated from disabled list |
| Alberto Rosario | C | 31.169 | Arizona Diamondbacks | Jackson (AA) | Activated from disabled list |
| Jeffrey Baez | OF | 24.241 | Chicago Cubs | Tennessee (AA) | Activated from disabled list |
| Jose Queliz | C | 25.325 | Arizona Diamondbacks | Jackson (AA) | DL-7 Injured |
| Bo Way | OF | 26.224 | Los Angeles Angels | Mobile (AA) | Activated from disabled list |
| Dietrich Enns | P | 27.043 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Conor Lillis-White | P | 25.341 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Matt Custred | P | 24.293 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Kohl Stewart | P | 23.264 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Cody Hall | P | 30.174 | - | | Released by Rays |
| Mitch Keller | P | 22.085 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Caleb Simpson | P | 26.287 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Ronnie Jebavy | OF | 24.042 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Sam Haggerty | IF | 24.033 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Jon Harris | P | 24.255 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Jason Martin | OF | 22.297 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Matt Den Dekker | CF-OF | 30.323 | New York Mets | Las Vegas (AAA) | Activated from disabled list |
| Jose Lobaton | C | 33.250 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Jordan Pacheco | 1B | 32.149 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Alexi Ogando | P | 34.267 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Cameron Hill | P | 24.035 | Cleveland Indians | Columbus (AAA) | DL-7 Injured |
| Juan Graterol | C | 29.134 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Jorge Polanco | 2B-SS | 24.358 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Cesar Cortez | OF | 19.088 | - | | Released by Astros |
| Patrick Mathis | OF | 22.097 | - | | Released by Astros |
| Josh Hart | OF | 23.269 | - | | Released by Marlins |
| Derrick Adams | P | 21.112 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Eddie Silva | IF | 22.077 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Marcelo Martinez | P | 21.322 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Hunter Speer | P | 23.041 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Caleb Sampen | P | 21.340 | Los Angeles Dodgers | Ogden (Rk) | Signed out of draft (Wright State) |
| Cal Stevenson | OF | 21.289 | Toronto Blue Jays | Bluefield (Rk) | Assigned to Bluefield (Rk) |
| Hunter Steinmetz | OF | 21.197 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Mitch Hickey | P | 22.230 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| James McArthur | P | 21.199 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Matt Kroon | 3B | 21.205 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Ethan DeCaster | P | 23.244 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Jesse Wilkening | C | 21.303 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Jack Perkins | P | 20.326 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Tarik Skubal | P | 21.220 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Stoney O'Brien | IF | 24.041 | Philadelphia Phillies | Gulf Coast Phillies West (Rk) | Assigned to Gulf Coast Phillies West (Rk) |
| Tim Cate | P | 20.271 | Washington Nationals | Auburn (A-) | Signed out of draft (Connecticut) |
| Chris Vallimont | P | 21.102 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Luke Jarvis | IF | 23.203 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Tyler Carr | P | 22.058 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Austin Ross | P | 23.316 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Devin Mann | IF | 21.137 | Los Angeles Dodgers | Great Lakes (A) | Placed on temporarily inactive list |
| Billy Cooke | OF-IF | 22.276 | Seattle Mariners | Clinton (A) | DL-7 Injured |
| Chris Roberts | P | 20.360 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Carlos Perez | C | 27.244 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Ariel Miranda | P | 29.169 | Seattle Mariners | Tacoma (AAA) | Placed on temporarily inactive list |
| Todd Hankins | 3B-OF | 27.222 | Cleveland Indians | Columbus (AAA) | DL-7 Injured |
| Regi Grace | P | 18.201 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Brian Auerbach | P | 21.302 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Blake Bennett | P | 22.113 | Philadelphia Phillies | Gulf Coast Phillies West (Rk) | Assigned to Gulf Coast Phillies West (Rk) |
| Michael Gizzi | P | 23.044 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Denny Bentley | P | 20.031 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Steele Walker | OF | 21.333 | Chicago White Sox | Arizona White Sox (Rk) | Signed out of draft (Oklahoma) |
