| Duane Underwood | P | 23.340 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Tennessee (AA) |
| Tyler Chatwood | SP | 28.191 | Chicago Cubs | Chicago Cubs (MLB) | Placed on Paternity Leave List |
| Michael Dunn | RP | 33.033 | Colorado Rockies | Lancaster (A+) | Assigned to Lancaster (A+) for rehab |
| Chris Tillman | SP | 30.071 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) for rehab |
| Yu Darvish | SP | 31.313 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) for rehab |
| Shae Simmons | RP | 27.295 | Chicago Cubs | Iowa (AAA) | Outrighted to minors |
| Trayce Thompson | CF | 27.102 | Chicago White Sox | Charlotte (AAA) | Outrighted to minors |
| Carlos Estevez | RP | 25.179 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) for rehab |
| Jonny Venters | P | 33.097 | Tampa Bay Rays | Tampa Bay Rays (MLB) | DL-10 Right hamstring strain |
| Austin Pruitt | RP | 28.298 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Luis Sardinas | SS | 25.040 | Baltimore Orioles | Norfolk (AAA) | Transferred to 60-day DL |
| Donnie Hart | RP | 27.292 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Tim Beckham | DH | 28.149 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Jesmuel Valentin | SS | 24.044 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Reinstated to active roster |
| Hector Neris | CL | 29.011 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Edubray Ramos | RP | 25.188 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-10 Right shoulder impingement |
| Mitchell Walding | SS | 25.288 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Ben Meyer | P | 25.146 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Caleb Smith | P | 26.333 | Miami Marlins | Miami Marlins (MLB) | DL-10 Left shoulder tightness |
| Martin Perez | SP | 27.082 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) for rehab |
| Evan Phillips | p | 23.287 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Mike Foltynewicz | SP | 26.262 | Atlanta Braves | Atlanta Braves (MLB) | Activated from DL |
| Brandon Kintzler | RP | 33.328 | Washington Nationals | Washington Nationals (MLB) | Activated from DL |
| Jefry Rodriguez | p | 24.334 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Clay Buchholz | SP | 33.315 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-10 Strained left oblique |
| Shelby Miller | SP | 27.258 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Chris Flexen | P | 23.359 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Tyler Bashlor | RP | 25.070 | New York Mets | New York Mets (MLB) | Recalled from Binghamton (AA) |
| Giovanny Gallegos | P | 26.316 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Kyle Higashioka | C | 28.066 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Clint Frazier | OF | 23.292 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Gary Sanchez | C | 25.205 | New York Yankees | New York Yankees (MLB) | DL-10 Right groin strain |
| Scott Oberg | RP | 28.104 | Colorado Rockies | Lancaster (A+) | Assigned to Lancaster (A+) for rehab |
| Ryan Lamarre | CF | 29.216 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Ryan Buchter | RP | 31.132 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL |
| Liam Hendriks | RP | 29.135 | Oakland Athletics | Oakland Athletics (MLB) | Designated for Assignment |
| Nick Martini | CF | 27.363 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Nick Basto | 3B | 24.085 | Washington Nationals | Washington Nationals (MLB) | Signed to Minor League Contract |
| Dariel Alvarez | OF | 29.230 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Matthew Hammonds | P | 23.033 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Franklin Perez | P | 20.201 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Keyder Aristigueta | 2B | 22.144 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Kyle Johnson | OF | 24.279 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Omar Herman | P | 21.096 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Ruddy Giron | SS | 21.172 | San Diego Padres | Arizona Padres 2 (Rk) | Assigned to Arizona Padres 2 (Rk) |
| Reinaldo Ilarraza | 2B | 19.164 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Malique Ziegler | OF | 21.290 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) |
| Carlos Diaz | 2B | 25.222 | Kansas City Royals | Arizona Royals (Rk) | Assigned to Arizona Royals (Rk) |
| Wes Darvill | 2B | 26.289 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Sandro Cabrera | P | 23.003 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) |
| Rudy Martin | OF | 22.146 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Yeison Santana | P | 21.243 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Matthew Foley | C | 24.071 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Rashad Crawford | OF | 24.253 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Miguel Eladio | SS | 22.046 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Kyle Goodbrand | P | 23.064 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Franyel Casadilla | P | 21.081 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Eric Wood | 3B | 25.215 | Pittsburgh Pirates | West Virginia (A-) | Assigned to West Virginia (A-) |
| Cesar Gonzalez | OF | 23.025 | - | | Released by Tigers |
| JP Sears | P | 22.127 | New York Yankees | Charleston (sc) (A) | DL-7 Injured |
| Jean Carrillo | C | 21.009 | Baltimore Orioles | Delmarva (A) | Activated from disabled list |
| Seamus Curran | 1B | 20.292 | Baltimore Orioles | Delmarva (A) | DL-7 Injured |
| Daniel Ramos | P | 23.111 | New York Yankees | Charleston (sc) (A) | Activated from disabled list |
| Tommy DeJuneas | P | 22.245 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Tyler Friis | 2B | 22.134 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Evan Guillory | P | 22.171 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Christian Donahue | IF | 23.052 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Hunter Schryver | P | 23.083 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Jesus Lage | SS | 20.206 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Manuel Rondon | P | 23.110 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Arden Pabst | C-IF | 23.103 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Josh Prevost | P | 26.162 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Nash Knight | IF | 25.278 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Chace Numata | C | 25.315 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Jon Kennedy | P | 22.279 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Ruben Alaniz | P | 27.011 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Jake Thomas | OF | 24.339 | - | | Announced retirement |
| Ronald Pena | P | 26.280 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| James Teague | P | 23.300 | Baltimore Orioles | Frederick (A+) | DL-7 Injured |
| Telmito Agustin | OF | 21.259 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Isaac Silva | P | 25.286 | Baltimore Orioles | Frederick (A+) | Activated from disabled list |
| Dustin Houle | C | 24.228 | Milwaukee Brewers | Carolina (A+) | Assigned to Carolina (A+) |
| Nick Basto | 3B | 24.085 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Sterling Sharp | P | 23.026 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Wyatt Short | P | 23.254 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Matt Peacock | P | 24.118 | Arizona Diamondbacks | Visalia (A+) | DL-7 Injured |
| Logan Taylor | IF | 24.276 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Nick Noonan | 2B | 29.052 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Tyler Wagner | P | 27.152 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Adam Law | OF-3B | 28.140 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Jason Vosler | IF | 24.292 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Zach Hedges | P | 25.247 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| James Norwood | P | 24.183 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Craig Brooks | P | 25.275 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Taylor Murphy | 3B | 25.234 | - | | Released by Braves |
| Jeff Ames | P | 27.145 | - | | Released by Nationals |
| Armando Araiza | C | 25.006 | Baltimore Orioles | Bowie (AA) | DL-7 Injured |
| Ronnie Jebavy | OF | 24.039 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Jaycob Brugman | OF | 26.159 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Francisco Diaz | C | 28.096 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Will LaMarche | P | 26.323 | - | | Released by Giants |
| Ian Parmley | OF | 28.188 | - | | Released by Blue Jays |
| Danny Muno | 2B | 29.136 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
| Sherman Johnson | 3B | 27.345 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Cameron Perkins | OF | 27.271 | Seattle Mariners | Tacoma (AAA) | Activated from disabled list |
| Logan Moon | OF | 26.131 | Kansas City Royals | Omaha (AAA) | DL-7 Injured |
| David Holmberg | P | 26.342 | Colorado Rockies | Albuquerque (AAA) | DL-7 Injured |
| Jackson Williams | C | 32.042 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from disabled list |
| Wynston Sawyer | C | 26.224 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Jordan Pacheco | 1B | 32.146 | Minnesota Twins | Rochester (AAA) | Activated from disabled list |
| Stuart Levy | C | 25.308 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Danny Espinosa | 2B | 31.061 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Johnny Hellweg | P | 29.239 | - | | Released by Pirates |
| Jake Thomas | OF | 24.339 | - | | Announced retirement |
| Jake Thomas | OF | 24.339 | - | | Announced retirement |
| Brandon Koch | P | 24.182 | Tampa Bay Rays | Charlotte (A+) | DL-7 Injured |
| Tyler Pill | P | 28.027 | Los Angeles Dodgers | Oklahoma City (AAA) | Placed on temporarily inactive list |
| Jake Thomas | OF | 24.339 | - | | Announced retirement |
| Jake Thomas | OF | 24.339 | - | | Announced retirement |
| Jake Thomas | OF | 24.339 | - | | Announced retirement |
| Juan Perez | SS | 26.237 | - | | Released by White Sox |
| Michael Fuchs | SS-3B | 22.??? | - | | Announced retirement |
| Bryan Torres | OF | 20.358 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Andrew Mitchell | P | 23.245 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Rylan Thomas | 3B | 21.000 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Joseivin Medina | OF | 18.144 | Pittsburgh Pirates | Bristol (Rk) | Assigned to Bristol (Rk) |
| Scott Kapers | C | 21.210 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Troy Dixon | CF | 21.120 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Ryan Weiss | P | 21.197 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Jackson Goddard | P | 21.195 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Bryce Montes de Oca | P | 22.063 | New York Mets | Brooklyn (A-) | DL-7 Injured |
| Kevin Magee | P | 22.176 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Chris Proctor | C | 21.109 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Luke Sherley | SS | 22.049 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Andrew Karp | P | 22.269 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Gus Varland | P | 21.231 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Matt Esparza | P | 23.307 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Adam Hill | P | 21.093 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Richie Palacios | IF | 21.040 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Kyle Marinconz | IF | 22.032 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Alexis Garcia | P | 26.160 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Jack Thoreson | C | 23.000 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Yasin Chentouf | CF | 21.007 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Chris Tillman | P | 30.071 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Rodney Theophile | | -- | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Adrian Morejon | P | 19.118 | San Diego Padres | Lake Elsinore (A+) | DL-7 Injured |
| Casey Mize | P | 21.055 | Detroit Tigers | Detroit Tigers (MLB) | Signed out of draft (Auburn) |
| Abel Estevez | P | 18.160 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Reid Anderson | P | 22.293 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Onix Vega | C | 19.291 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Jonathan Quintana | OF | 23.214 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Nick Decker | OF | 18.267 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (New Jersey HS) |
| Brian Metoyer | P | 21.224 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Avery Tuck | OF | 20.179 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Nicholas Ernst | P | 21.302 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Lisandro Santos | P | 19.336 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Edwin Jackson | SP | 34.290 | Oakland Athletics | Oakland Athletics (MLB) | Contract purchased from minors |
