| Paulo Orlando | RF | 32.218 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Brad Miller | 1B | 28.232 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Designated for Assignment |
| Ronny Rodriguez | SS | 26.051 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Alex Wilson | RP | 31.216 | Detroit Tigers | Detroit Tigers (MLB) | Activated from DL |
| Paul Blackburn | SP | 24.185 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL |
| Bruce Maxwell | C | 27.169 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Boog Powell | OF | 25.144 | Oakland Athletics | Oakland Athletics (MLB) | Transferred to 60-day DL |
| Preston Guilmet | RP | 30.316 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Designated for Assignment |
| Greg Garcia | 3B-SS | 28.303 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Reinstated to active roster |
| Steven Baron | C | 27.182 | St. Louis Cardinals | Memphis (AAA) | Outrighted to minors |
| Jalen Beeks | P | 24.332 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Bobby Poyner | p | 25.188 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Greg Holland | CL | 32.199 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) for rehab |
| Matt Bowman | RP | 27.007 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) for rehab |
| Jason Castro | C | 30.355 | Minnesota Twins | Minnesota Twins (MLB) | Transferred to 60-day DL |
| Trevor May | RP | 28.257 | Minnesota Twins | Rochester (AAA) | Activated from DL and assigned to Rochester (AAA) |
| Tony Cingrani | RP | 28.337 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Left shoulder strain |
| Caleb Ferguson | P | 21.340 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Edward Paredes | P | 31.250 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Pedro Baez | RP | 30.088 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Trevor Richards | p | 25.023 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Tyler Cloyd | SP-RP | 31.022 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Jake Bauers | 1B-LF | 22.245 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Xavier Cedeno | RP | 31.285 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Tyler Brown | 2B | 23.140 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Garrett Davila | P | 21.141 | Kansas City Royals | Lexington (A) | DL-7 Injured |
| Colby Fitch | C | 22.316 | Philadelphia Phillies | Lakewood (A) | DL-7 Injured |
| John Riley | C | 24.113 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Frank Rubio | P | 23.045 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Janser Lara | P | 21.301 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Cole Stobbe | SS | 20.281 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Jean Carlos Mejia | P | 21.285 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Adrian De Horta | P | 23.086 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| Jose Soriano | P | 19.230 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Blayne Enlow | P | 19.078 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Evan Guillory | P | 22.153 | St. Louis Cardinals | Peoria (A) | Placed on temporarily inactive list |
| Levi MaVorhis | P | 23.311 | St. Louis Cardinals | Peoria (A) | DL-7 Injured |
| Jordan Scheftz | P | 22.281 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Riley Echols | P | 23.056 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Felix Tati | P | 21.067 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Brian Shaffer | P | 21.299 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Jeff Bain | P | 22.096 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Nick Brown | P | 23.199 | - | | Released by Twins |
| Kyle Nelson | P | 21.334 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Mandy Alvarez | IF | 23.328 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Jarett Rindfleisch | C | 22.277 | Miami Marlins | Jupiter (A+) | |
| Alexis Tapia | P | 22.302 | Tampa Bay Rays | Charlotte (A+) | Activated from disabled list |
| Jake Fraley | OF | 23.013 | Tampa Bay Rays | Charlotte (A+) | Activated from disabled list |
| Evan Kruczynski | P | 23.068 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Jim Voyles | P | 23.079 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Spenser Watkins | P | 25.284 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Peter Maris | IF | 24.264 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Troy Montgomery | OF | 23.298 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Jon Kennedy | P | 22.261 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Nathaniel Lowe | 1B | 22.336 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Reimin Ramos | P | 22.041 | - | | Released by Rays |
| Connor Johnstone | P | 23.246 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Devin Williams | P | 23.259 | Milwaukee Brewers | Carolina (A+) | Assigned to Carolina (A+) |
| Zach Plesac | P | 23.137 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Triston McKenzie | P | 20.309 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Chase Williams | P | 25.196 | - | | Released by Brewers |
| Kelvin Beltre | SS | 21.255 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Jorge Ona | OF | 21.158 | San Diego Padres | Lake Elsinore (A+) | Activated from disabled list |
| Luis Alejandro Basabe | 2B | 21.285 | Arizona Diamondbacks | Visalia (A+) | DL-7 Injured |
| Brandon Van Horn | IF | 24.171 | San Francisco Giants | San Jose (A+) | Placed on temporarily inactive list |
| Reid Humphreys | SS | 23.198 | Colorado Rockies | Lancaster (A+) | Activated from disabled list |
| Parker Curry | P | 24.198 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Andrew Sopko | P | 23.304 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Edwin Diaz | SS | 22.287 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Carlos Sierra | P | 23.232 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Shea Spitzbarth | P | 23.246 | Los Angeles Dodgers | Tulsa (AA) | Activated from disabled list |
| Forrest Whitley | P | 20.265 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
| Logan Ondrusek | P | 33.114 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Adam Law | OF-3B | 28.122 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Brandon Lowe | IF | 23.336 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Anthony Marzi | P | 25.192 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Casey Schroeder | C | 24.330 | Chicago White Sox | Birmingham (AA) | Activated from disabled list |
| Quintin Torres-Costa | P | 23.269 | Milwaukee Brewers | Biloxi (AA) | Activated from disabled list |
| Darren Seferina | 2B | 24.134 | Milwaukee Brewers | Biloxi (AA) | DL-7 Injured |
| Tito Polo | OF | 23.288 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Omar Bencomo | P | 29.117 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Sal Giardina | C | 26.038 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Harold Castro | 2B | 24.189 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Nick Sergakis | 3B | 25.062 | New York Mets | Binghamton (AA) | Activated from disabled list |
| Rey Navarro | 3B-2B | 28.167 | New York Yankees | Trenton (AA) | DL-7 Injured |
| Ryan Bollinger | P | 27.123 | New York Yankees | Trenton (AA) | Activated from disabled list |
| Drew Stankiewicz | 2B | 24.354 | Philadelphia Phillies | Reading (AA) | Activated from disabled list |
| Emmanuel Marrero | IF | 25.022 | Philadelphia Phillies | Reading (AA) | DL-7 Injured |
| Vladimir Guerrero | OF | 19.083 | Toronto Blue Jays | New Hampshire (AA) | DL-7 Injured |
| Cory Taylor | P | 24.175 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Joey Wong | SS-3B | 30.056 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Caleb Gindl | OF | 29.280 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Armando Araiza | C | 24.353 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Jonah Arenado | 3B | 23.124 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Kyle Hoppy | CF | 27.030 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Nelson Gonzalez | P | 28.112 | Colorado Rockies | Albuquerque (AAA) | Activated from disabled list |
| David Holmberg | P | 26.324 | Colorado Rockies | Albuquerque (AAA) | Placed on temporarily inactive list |
| Alejandro Garcia | OF | 26.352 | - | | Released by Astros |
| Aaron Laffey | P | 33.053 | - | | Announced retirement |
| Christian Colon | 2B-SS | 29.024 | New York Mets | Las Vegas (AAA) | Placed on temporarily inactive list |
| Jacob Turner | P | 27.017 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Sam Lewis | P | 26.242 | Arizona Diamondbacks | Jackson (AA) | DL-7 Injured |
| Aaron Laffey | P | 33.053 | - | | Announced retirement |
| Nick Plummer | OF | 21.311 | St. Louis Cardinals | Peoria (A) | Activated from disabled list |
| Aaron Laffey | P | 33.053 | - | | Announced retirement |
