| Gordon Beckham | 2B | 31.257 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Paul Blackburn | SP | 24.178 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) for rehab |
| Oliver Drake | RP | 31.138 | Los Angeles Angels | Los Angeles Angels (MLB) | Claimed off waivers from Indians by Angels |
| Trevor Gott | RP | 25.278 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Ryan Madson | RP | 37.276 | Washington Nationals | Washington Nationals (MLB) | Activated from DL |
| Ryan Rua | 1B-LF | 28.081 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Adrian Beltre | 3B | 39.054 | Texas Rangers | Texas Rangers (MLB) | Activated from DL |
| Tony Cruz | C | 31.286 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Curt Casali | C | 29.203 | Cincinnati Reds | Louisville (AAA) | Traded from Rays to Reds for cash |
| Dustin Peterson | 3B | 23.263 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Peter Bourjos | LF | 31.061 | Atlanta Braves | Atlanta Braves (MLB) | Contract purchased from minors |
| Aaron Blair | SP | 26.005 | | | Released by Braves |
| Nick Goody | RP | 26.330 | Cleveland Indians | Cleveland Indians (MLB) | Transferred to 60-day DL |
| Ben Taylor | RP | 25.200 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Shane Bieber | P | 23.000 | Cleveland Indians | Cleveland Indians (MLB) | Contract purchased from minors |
| Pat Venditte | RP | 32.335 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Clayton Kershaw | SP | 30.073 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Dee Gordon | CF | 30.039 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Grayson Greiner | C | 25.232 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Dylan Cozens | OF | 24.000 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Rhys Hoskins | LF | 25.075 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-10 Fractured jaw |
| Drew Hutchison | RP | 27.282 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Designated for Assignment |
| Mark Leiter | P | 27.079 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Ronny Rodriguez | SS | 26.044 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Carlos Ramirez | OF | 27.037 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Khris Davis | DH | 30.162 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL |
| Aaron Slegers | P | 25.269 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Tyler Duffey | RP | 27.155 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Carlos Martinez | SP | 26.253 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) for rehab |
| Enmanuel de Jesus | P | 24.145 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Carlos Acevedo | P | 23.246 | Washington Nationals | Hagerstown (A) | DL-7 Injured |
| Randy Alcantara | P | 21.203 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Connor Brogdon | P | 23.122 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Taylor Ahearn | OF | 23.187 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Jordan Balazovic | P | 19.256 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Emerson Jimenez | SS | 23.166 | Toronto Blue Jays | Lansing (A) | Activated from disabled list |
| Sarkis Ohanian | P | 24.298 | Cincinnati Reds | Dayton (A) | Activated from disabled list |
| Tanner Kiest | P | 23.257 | Minnesota Twins | Cedar Rapids (A) | Reinstated to active roster |
| Zach McKinstry | SS | 23.032 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Andy Ravel | P | 23.231 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Max Wotell | P | 21.260 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Marshall Kasowski | P | 23.082 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| James Carter | P | 24.082 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Diomar Lopez | P | 21.167 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Jared Carkuff | P | 24.279 | - | | Released by Padres |
| Sean Poppen | P | 24.077 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Jose Antequera | SS | 22.304 | Philadelphia Phillies | Clearwater (A+) | DL-7 Injured |
| Danny Hudzina | IF | 24.093 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Nick Howard | P | 25.055 | Cincinnati Reds | Daytona (A+) | Reinstated to active roster |
| Michael Gibbons | P | 25.037 | New York Mets | St. Lucie (A+) | Activated from disabled list |
| Jose Godoy | C | 23.230 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Shawn Semple | P | 22.235 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Matt Pobereyko | P | 26.159 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Josh Prevost | P | 26.137 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Brian Mims | 2B | 22.078 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Thomas McIlraith | P | 24.103 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Nick Hartman | P | 23.219 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Elvis Araujo | P | 26.321 | Baltimore Orioles | Frederick (A+) | DL-7 Injured |
| Algenis Martinez | P | 24.261 | Boston Red Sox | Salem (A+) | Activated from disabled list |
| Francisco Jimenez | P | 23.239 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Reid Humphreys | SS | 23.191 | Colorado Rockies | Lancaster (A+) | DL-7 Injured |
| Matt Ball | P | 23.067 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Franklin Navarro | C | 23.226 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Blake Smith | P | 25.292 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| Matt Milburn | P | 24.306 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Conner Menez | P | 23.002 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Matthew Batten | IF | 22.344 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Anthony Mciver | P | 26.053 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Colby Blueberg | P | 25.020 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| A.J. Franks | P | 22.341 | Seattle Mariners | Modesto (A+) | Assigned to Modesto (A+) |
| Julian Leon | C | 22.128 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Forrestt Allday | OF | 27.037 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| River Stevens | 2B-3B | 26.142 | San Diego Padres | San Antonio (AA) | DL-7 Injured |
| Trevor Megill | P | 24.177 | San Diego Padres | San Antonio (AA) | DL-7 Injured |
| Ralph Garza | P | 24.055 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Tyler Pill | P | 28.002 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Juniel Querecuto | 2B-SS | 25.254 | Arizona Diamondbacks | Jackson (AA) | DL-7 Injured |
| Daniel Procopio | P | 22.256 | Los Angeles Angels | Mobile (AA) | Activated from disabled list |
| Daury Torrez | P | 24.354 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jose Queliz | C | 25.297 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| Brad Goldberg | P | 28.099 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Jose Garcia | C | 23.209 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Zac Houston | P | 23.182 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Dusty Isaacs | P | 26.298 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| John Polonius | SS-2B | 27.138 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Montana Durapau | P | 26.065 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Michael Perez | C | 25.297 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Colton Plaia | C | 27.248 | New York Mets | Las Vegas (AAA) | Activated from disabled list |
| Dario Alvarez | P | 29.134 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
| Charlie Meyer | C | 25.141 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Adam Loewen | OF | 34.052 | - | | Released by Rangers |
| Louis Head | P | 28.038 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Oscar Hernandez | C | 24.326 | Boston Red Sox | Pawtucket (AAA) | Reinstated to active roster |
| Aaron Blair | P | 26.005 | Atlanta Braves | Gwinnett (AAA) | Activated from disabled list |
| Adron Chambers | OF | 31.235 | Philadelphia Phillies | Lehigh Valley (AAA) | Reinstated to active roster |
| Matt McBride | C | 33.008 | Philadelphia Phillies | Lehigh Valley (AAA) | Reinstated to active roster |
| Jose Mayorga | C | 25.284 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Cody Satterwhite | P | 31.124 | - | | Released by Nationals |
| Andrew Pullin | 2B | 24.248 | - | | Announced retirement |
| Austin Gomber | P | 24.189 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| John Gant | RP | 25.298 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Tyler O'Neill | c | 22.344 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Alex Reyes | SP | 23.275 | St. Louis Cardinals | St. Louis Cardinals (MLB) | DL-10 Right lat strain |
| Luke Voit | C | 27.107 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Mike Mayers | RP | 26.177 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
