| Chase Anderson | SP | 30.173 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Activated from DL |
| Junichi Tazawa | RP | 31.349 | | | Released by Marlins |
| Richard Urena | SS | 22.085 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Tyler Webb | P | 27.305 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Tom Kahnle | RP | 28.287 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (A) for rehab |
| Randal Grichuk | RF | 26.282 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) for rehab |
| Cody Bolton | P | 19.336 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Dylan Busby | OF | 22.175 | Pittsburgh Pirates | West Virginia (A) | DL-7 Injured |
| Shael Mendoza | 2B | 21.218 | Colorado Rockies | Asheville (A) | DL-7 Injured |
| Jakob Hernandez | P | 22.002 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Seuly Matias | OF | 19.259 | Kansas City Royals | Lexington (A) | Reinstated to active roster |
| Jhailyn Ortiz | 1B-OF | 19.184 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Nerluis Martinez | C | 22.041 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Connor Brogdon | P | 23.112 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Julio Pinto | P | 22.185 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Danny Mayer | OF | 22.331 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| David Parkinson | P | 22.159 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Colby Fitch | C | 22.299 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Zacrey Law | OF | 21.317 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Austen Wade | OF | 22.094 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Ernie Clement | IF | 22.060 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Chris Betts | C | 21.072 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Jesse Berardi | SS | 22.129 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Jose Medina | OF | 23.096 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Darwin Alvarado | OF | 19.192 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Ignacio Valdez | OF | 22.310 | - | | Released by Tigers |
| Alex Robinson | P | 23.283 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| Logan Lombana | P | 23.308 | Minnesota Twins | Fort Myers (A+) | DL-7 Injured |
| Blake Bivens | P | 22.284 | Tampa Bay Rays | Charlotte (A+) | Activated from disabled list |
| Alberto Tirado | P | 23.162 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Will Carter | P | 25.123 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Pat Ruotolo | P | 23.126 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| John Polonius | SS-2B | 27.128 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Parker Curry | P | 24.181 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Ryan Helsley | P | 23.307 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Ralph Garza | P | 24.045 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Seby Zavala | C | 24.266 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Casey Schroeder | C | 24.313 | Chicago White Sox | Birmingham (AA) | Activated from disabled list |
| Randy LeBlanc | P | 26.075 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Zach Jones | P | 27.168 | Minnesota Twins | Chattanooga (AA) | Activated from disabled list |
| Kyle Bird | P | 25.039 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Brody Koerner | P | 24.216 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Connor Overton | P | 24.301 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Jacob Waguespack | P | 24.197 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Dusty Isaacs | P | 26.288 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Ryan Halstead | P | 26.008 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Sean Brady | P | 23.346 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Erik Swanson | P | 24.259 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| David Ledbetter | P | 26.098 | - | | Announced retirement |
| Wynton Bernard | OF | 27.239 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Trent Thornton | P | 24.233 | Houston Astros | Fresno (AAA) | DL-7 Injured |
| Logan Taylor | P | 26.160 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Ivan Pineyro | P | 26.235 | Los Angeles Angels | Salt Lake (AAA) | Placed on temporarily inactive list |
| Sherman Johnson | 3B | 27.310 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Nelson Gonzalez | P | 28.095 | Colorado Rockies | Albuquerque (AAA) | Activated from disabled list |
| Greg Belton | P | 25.141 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Lane Adams | OF | 28.189 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Ezequiel Carrera | OF | 30.345 | New York Mets | Las Vegas (AAA) | Signed to Minor League Contract |
| Cody Martin | P | 28.259 | New York Mets | Las Vegas (AAA) | Signed to Minor League Contract |
| Keith Hessler | P | 29.067 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
| J.T. Brubaker | P | 24.185 | Pittsburgh Pirates | Indianapolis (AAA) | Reinstated to active roster |
| Casey Gillaspie | 1B | 25.116 | Chicago White Sox | Charlotte (AAA) | Placed on temporarily inactive list |
| Michael Saunders | CF | 31.183 | Chicago White Sox | Charlotte (AAA) | Signed to Minor League Contract |
| Anibal Sanchez | SP | 34.084 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) for rehab |
| Lonnie Chisenhall | RF | 29.229 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) for rehab |
| Odrisamer Despaigne | RP | 31.047 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Dillon Peters | P | 25.263 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Drew Robinson | 3B | 26.031 | Texas Rangers | Round Rock (AAA) | Activated from DL and assigned to Round Rock (AAA) |
| Matt Bush | RP | 32.102 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Kevin Jepsen | RP | 33.299 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| Carlos Asuaje | 2B | 26.201 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Freddy Peralta | P | 21.351 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Mark Melancon | CL | 33.054 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) for rehab |
| Billy McKinney | CF | 23.271 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) for rehab |
| Greg Bird | 1B | 25.193 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) for rehab |
| Clint Frazier | OF | 23.257 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Giovanny Gallegos | P | 26.281 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Josh Phegley | C | 30.099 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Bruce Maxwell | C | 27.152 | Oakland Athletics | Oakland Athletics (MLB) | Reinstated to active roster |
| Dustin Garneau | C | 30.282 | Oakland Athletics | Nashville (AAA) | Designated for Assignment |
| Howie Kendrick | 2B | 34.314 | Washington Nationals | Washington Nationals (MLB) | Transferred to 60-day DL |
| Tim Collins | RP | 28.273 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from minors |
| Jose Lobaton | C | 33.212 | New York Mets | New York Mets (MLB) | Outrighted to minors |
| Austin Hedges | C | 25.276 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) for rehab |
| David Ledbetter | P | 26.098 | - | | Announced retirement |
| Jonathan Singleton | 1B | 26.246 | - | | Released by Astros |
| David Ledbetter | P | 26.098 | - | | Announced retirement |
