| Jeff Ames | P | 26.204 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Matt Andriese | SP | 27.360 | Tampa Bay Rays | Durham (AAA) | Activated from disabled list |
| Cal Becker | p | 24.075 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| J.R. Bradley | P | 25.075 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| Geoff Broussard | P | 26.336 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Henry Centeno | P | 22.364 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| Clay Chandler | p | 23.118 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Gavin Collins | c | 22.037 | Cleveland Indians | Lynchburg (A+) | Activated from disabled list |
| Malik Collymore | SS | 22.116 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Troy Conyers | p | 23.134 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Craig Dedelow | of | 22.281 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| Cody Dickson | P | 25.118 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Phil Ervin | OF | 25.037 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Yoel Espinal | P | 24.289 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Bobby Eveld | p | 25.263 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Max Gamboa | p | 21.275 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Activated from disabled list |
| Daniel Garmendia | p | 22.320 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Jeff Gelalich | OF | 26.160 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Tony Gonsolin | p | 23.101 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| John Gorman | p | 25.186 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Ashton Goudeau | P | 25.031 | Kansas City Royals | Arizona Royals (Rk) | Activated from disabled list |
| Austin Grebeck | of | 23.015 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Anjul Hernandez | p | 21.234 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| Ronald Herrera | P | 22.112 | New York Yankees | Gulf Coast Yankees (Rk) | Activated from disabled list |
| Ryan Horstman | P | 25.034 | Seattle Mariners | Arkansas (AA) | Activated from disabled list |
| Austin Hutchison | p | 22.136 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Dany Jimenez | p | 23.243 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| James Jones | RF | 28.333 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) |
| Felix Jorge | P | 23.233 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Denis Karas | 3b | 21.270 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Kyle Kendrick | SP | 32.362 | Boston Red Sox | Pawtucket (AAA) | Activated from disabled list |
| Stephen Kerr | 2b | 22.244 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Trace Loehr | SS | 22.092 | Oakland Athletics | Beloit (A) | Activated from disabled list |
| Nolan Martinez | p | 19.054 | New York Yankees | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Domenic Mazza | p | 23.025 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Kyle Mcgowin | P | 25.270 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Anthony Mciver | p | 25.137 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Reydel Medina | OF | 24.190 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Anthony Miller | 1b | 22.323 | Cleveland Indians | Lynchburg (A+) | Activated from disabled list |
| Yeudy Minaya | p | 21.104 | Oakland Athletics | Arizona Athletics (Rk) | Reinstated to active roster |
| Bryan Mitchell | RP | 26.126 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Alex Monsalve | C | 25.123 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Patrick Murphy | P | 22.074 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Dorssys Paulino | SS | 22.275 | Cleveland Indians | Akron (AA) | Activated from disabled list |
| Manny Pazos | c | 22.212 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| R.J. Peace | p | 20.060 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Cameron Perkins | OF | 26.330 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Chris Pike | P | 24.316 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Juan Pineda | 2b | 19.204 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Anderson Polanco | p | 24.351 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Cody Ponce | p | 23.120 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Ryan Riga | p | 24.305 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Dalton Rodriguez | P | 21.003 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Henrry Rosario | OF | 24.140 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Blake Rutherford | of | 20.113 | Chicago White Sox | Kannapolis (A) | Activated from disabled list |
| Edgar Santana | p | 25.312 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Jordan Schafer | cf-RF | 30.353 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Jesse Scholtens | p | 23.139 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Carlos Sepulveda | 2b | 20.361 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Aaron Slegers | P | 24.353 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Jordan Smith | 3B | 27.049 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| William Soto | P | 21.192 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Cody Stashak | p | 23.080 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Keaton Steele | P | 25.298 | Minnesota Twins | Chattanooga (AA) | Activated from disabled list |
| Michael Suarez | p | 22.155 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| Tommy Thorpe | P | 24.337 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Alberto Tirado | P | 22.256 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Activated from disabled list |
| Josh Turley | P | 26.362 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Nik Turley | P | 27.346 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Mitchell Walding | SS | 24.347 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Activated from disabled list |
| Jordan Watson | p | 23.343 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Lachlan Wells | p | 20.177 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Garrett Whitlock | p | 21.073 | New York Yankees | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Wes Wilson | C | 28.005 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Eric Yardley | P | 27.005 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Tyler Zuber | p | 22.068 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Rajai Davis | CF | 36.308 | Boston Red Sox | Boston Red Sox (MLB) | Traded from Athletics to Red Sox for Rafael Rincones |
| Steve Selsky | CF | 28.034 | Boston Red Sox | Pawtucket (AAA) | Designated for Assignment |
| Kyle Farmer | IF | 27.006 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Alejandro Chacin | P | 24.060 | Cincinnati Reds | Cincinnati Reds (MLB) | Contract purchased from minors |
| Luke Farrell | p | 26.077 | Cincinnati Reds | Cincinnati Reds (MLB) | Recalled from Louisville (AAA) |
| Blake Wood | RP | 32.015 | Cincinnati Reds | Cincinnati Reds (MLB) | Designated for Assignment |
| Drew Anderson | RP | 23.154 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Ryan Sherriff | P | 27.090 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Contract purchased from minors |
| Trevor Rosenthal | RP | 27.086 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Transferred to 60-day DL |
| Angel Sanchez | P | 27.268 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Contract purchased from minors |
| Jason Kipnis | 2B | 30.142 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Recurring strained right hamstring |
| Erik Gonzalez | 2B | 25.358 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Jackie Bradley | CF | 27.126 | Boston Red Sox | Boston Red Sox (MLB) | DL-10 Sprained left thumb |
| Deven Marrero | 2B | 26.363 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Vidal Nuno | RP | 30.028 | Baltimore Orioles | Norfolk (AAA) | Outrighted to minors |
| David Phelps | RP | 30.318 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Leonys Martin | CF | 29.170 | Seattle Mariners | Seattle Mariners (MLB) | Designated for Assignment |
| A.J. Minter | RP | 23.355 | Atlanta Braves | Atlanta Braves (MLB) | Contract purchased from minors |
| Andrew Kittredge | P | 27.159 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Miguel Castro | P | 22.242 | Baltimore Orioles | Baltimore Orioles (MLB) | Reinstated from Bereavement list |
| John Curtiss | P | 24.140 | Minnesota Twins | Minnesota Twins (MLB) | Contract purchased from minors |
| Trevor Plouffe | 3B | 31.069 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Designated for Assignment |
| Tim Melville | P | 27.318 | Minnesota Twins | Minnesota Twins (MLB) | Designated for Assignment |
| Daniel Gossett | P | 24.283 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Paolo Espino | P | 30.225 | Milwaukee Brewers | Colorado Springs (AAA) | Designated for Assignment |
| Steven Matz | SP | 26.086 | New York Mets | New York Mets (MLB) | DL-10 Ulnar nerve irritation, left elbow |
| Mark Lowe | RP | 34.077 | | | Released by White Sox |
| Alberth Martinez | CF | 26.212 | | | Released by Padres |
| Bubba Starling | OF | 25.020 | Kansas City Royals | Omaha (AAA) | DL-7 Strained oblique |
| Drew Gagnon | P | 27.058 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Kohl Stewart | P | 22.320 | Minnesota Twins | Fort Myers (A+) | DL-7 Injured |
| Spencer Johnson | of | 23.295 | | | Released by Astros |
| John Straka | P | 27.216 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Ryan Hissey | c | 23.137 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Sam Coonrod | P | 24.335 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Brandon Lawson | p | 22.253 | Tampa Bay Rays | Charlotte (A+) | Placed on temporary inactive list |
| Norge Ruiz | p | 23.161 | Oakland Athletics | Stockton (A+) | DL-7 Injured |
| Ty Barkell | p | 24.164 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| Christian Cavaness | of | 23.160 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Dustin Hunt | p | 23.021 | | | Released by Astros |
| Jack Meggs | of | 22.127 | Oakland Athletics | Vermont (A-) | DL-60 Injured |
| Tyler Lancaster | c | 23.022 | St. Louis Cardinals | State College (A-) | Suspended 76 games for violating minor league drug policy |
| Filyer Sanchez | p | 20.196 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to GCL Braves (Rk) |
| Igor Baez | c | 22.078 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to GCL Marlins (Rk) |
