| Angel German | p | 21.067 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Traded from Pirates with Oneil Cruz to Dodgers for Tony Watson |
| Oneil Cruz | 3b | 18.300 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Traded from Dodgers with Angel German to Pirates for Tony Watson |
| Tim Beckham | SS | 27.185 | Baltimore Orioles | Baltimore Orioles (MLB) | Traded from Rays to Orioles for Tobias Myers |
| Tobias Myers | p | 18.360 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Traded from Orioles to Rays for Tim Beckham |
| Brandon Kintzler | CL | 32.364 | Washington Nationals | Washington Nationals (MLB) | Traded from Twins to Nationals for Tyler Watson |
| Tyler Watson | p | 20.070 | Minnesota Twins | Minnesota Twins (MLB) | Traded from Nationals to Twins for Brandon Kintzler |
| Michael Feliz | RP | 24.033 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Lance McCullers | SP | 23.302 | Houston Astros | Houston Astros (MLB) | DL-10 Lower back discomfort |
| A.J. Reed | 1B | 24.082 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Teoscar Hernandez | LF | 24.289 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded to Blue Jays with Nori Aoki to Blue Jays for Francisco Liriano |
| Norichika Aoki | RF | 35.207 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded by Astros with Teoscar Hernandez to Blue Jays for Francisco Liriano |
| Francisco Liriano | SP | 33.279 | Houston Astros | Houston Astros (MLB) | Traded from Blue Jays to Astros for Norichika Aoki and eoscar Hernandez |
| David Hernandez | RP | 32.079 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Traded from Angels to Diamondbacks for Luis Madero |
| Luis Madero | p | 20.107 | Los Angeles Angels | Los Angeles Angels (MLB) | Traded from Diamondbacks to Angels for David Hernandez |
| Jeremy Jeffress | RP | 29.314 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Traded from Rangers to Brewers for Taylor Scott |
| Tayler Scott | P | 25.060 | Texas Rangers | Texas Rangers (MLB) | Traded from Brewers to Rangers for Jeremy Jeffress |
| Kirk Nieuwenhuis | CF-LF | 29.359 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Designated for Assignment |
| Perci Garner | RP | 28.230 | Cleveland Indians | Akron (AA) | Designated for Assignment |
| Joe Smith | RP | 33.131 | Cleveland Indians | Cleveland Indians (MLB) | Traded from Blue Jays to Indians for Thomas Pannone and Samad Taylor |
| Thomas Pannone | OF | 23.094 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded from Indians with Samad Taylor to Blue Jays for Joe Smith |
| Samad Taylor | 2b | 19.111 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded from Indians with Thomas Pannone to Blue Jays for Joe Smith |
| Nick Franklin | LF | 26.151 | Los Angeles Angels | Los Angeles Angels (MLB) | Outrighted to minors |
| Tyler Olson | P | 27.302 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Josh Tomlin | SP | 32.285 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Strained left hamstring |
| Jorge Mateo | SS | 22.038 | Oakland Athletics | Oakland Athletics (MLB) | Traded from Yankees with Dustin Fowler and James Kaprielian to Athletics for Sonny Gray |
| James Kaprielian | p | 23.151 | Oakland Athletics | Oakland Athletics (MLB) | Traded from Yankees with Jorge Mateo and Dustin Fowler to Athletics for Sonny Gray |
| Dustin Fowler | CF | 22.214 | Oakland Athletics | Oakland Athletics (MLB) | Traded from Yankees with James Kaprielian and Jorge Mateo to Athletics for Sonny Gray |
| Sonny Gray | SP | 27.266 | New York Yankees | New York Yankees (MLB) | Traded from Athletics to Yankees for Dustin Fowler, James Kaprielian and Jorge Mateo |
| Joshua Rutledge | 3B-2B | 28.101 | Boston Red Sox | Boston Red Sox (MLB) | Transferred to 60-day DL |
| Addison Reed | CL | 28.216 | Boston Red Sox | Boston Red Sox (MLB) | Traded from Mets to Red Sox for Gerson Bautista, Jamie Callahan and Stephen Nogosek |
| Gerson Bautista | p | 22.061 | New York Mets | New York Mets (MLB) | Traded from Red Sox with Jamie Callahan and Stephen Nogosek to Mets for Addison Reed |
| Jamie Callahan | P | 22.341 | New York Mets | New York Mets (MLB) | Traded from Red Sox with Gerson Bautista and Stephen Nogosek to Mets for Addison Reed |
| Steve Nogosek | p | 22.201 | New York Mets | New York Mets (MLB) | Traded from Red Sox with Jamie Callahan and Gerson Bautista to Mets for Addison Reed |
| Jumbo Diaz | RP | 33.155 | Houston Astros | Houston Astros (MLB) | Signed to Minor League Contract |
| Jonathan Holder | RP | 24.052 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Adam Rosales | SS-2B | 34.072 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Traded from Athletics to Diamondbacks for Jeferson Mejia |
| Jeferson Mejia | P | 22.363 | Oakland Athletics | Oakland Athletics (MLB) | Traded from Diamondbacks to Athletics for Adam Rosales |
| Austin Maddox | C | 26.079 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Jeremy Guthrie | SP | 38.114 | | | Announced retirement |
| Emilio Bonifacio | RF | 32.099 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Signed to Minor League Contract |
| Dylan Floro | P | 26.216 | Chicago Cubs | Iowa (AAA) | Designated for Assignment |
| John Hicks | 1B | 27.334 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Alex Avila | C | 30.183 | Chicago Cubs | Chicago Cubs (MLB) | Traded by Tigers with Justin Wilson to Cubs for Isaac Paredes and Jeimer Candelario |
| Justin Wilson | RP | 29.348 | Chicago Cubs | Chicago Cubs (MLB) | Traded by Tigers with Alex Avila to Cubs for Isaac Paredes and Jeimer Candelario |
| Isaac Paredes | ss | 18.163 | Detroit Tigers | Detroit Tigers (MLB) | Traded by Cubs with Jeimer Candelario to Tigers for Alex Avila and Justin Wilson |
| Jeimer Candelario | 3B | 23.249 | Detroit Tigers | Detroit Tigers (MLB) | Traded by Cubs with Isaac Paredes to Tigers for Alex Avila and Justin Wilson |
| Shane Peterson | DH-LF | 29.171 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Outrighted to minors |
| John Axford | RP | 34.121 | | | Released by Athletics |
| Chris Owings | SS-RF | 25.354 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-60 Fractured right middle finger |
| Aramis Ademan | ss | 18.321 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Eliezer Alvarez | 2B-3B | 22.289 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Elliot Ashbeck | p | 23.257 | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| Leudys Baez | of | 21.035 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Gerson Bautista | p | 22.061 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Preston Beck | OF | 26.278 | Texas Rangers | Round Rock (AAA) | Activated from disabled list |
| Aaron Blair | SP | 25.066 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Ben Braymer | p | 23.094 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Cael Brockmeyer | C-1B | 25.297 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Casey Brown | P | 24.095 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Austin Bush | 1b | 21.222 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Jamie Callahan | P | 22.341 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Luis Campusano | c | 18.305 | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| Gabriel Cancel | ss | 20.235 | Kansas City Royals | Lexington (A) | Activated from disabled list |
| Rafael Carvajal | p | 20.260 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Daniel Corcino | P | 26.339 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Dylan Covey | SP | 25.352 | Chicago White Sox | Arizona White Sox (Rk) | Assigned to Arizona White Sox (Rk) for rehab |
| Jonathon Crawford | P | 25.273 | Cincinnati Reds | Daytona (A+) | Activated from disabled list |
| Alan Crowley | c | 21.149 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Johnny Cueto | SP | 31.166 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) for rehab |
| Ike Davis | 1B | 30.131 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Jumbo Diaz | RP | 33.155 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Tim Dillard | P | 34.012 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Cody Dube | p | 22.283 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Jean Carlos Encarnacion | 3b | 19.195 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Nick Franklin | LF | 26.151 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Vladimir Frias | RF-LF | 30.328 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Gerson Garabito | p | 21.347 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Elniery Garcia | P | 22.219 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Activated from disabled list |
| Sal Giardina | C | 25.092 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Terrance Gore | LF | 26.053 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| A.J. Griffin | SP | 29.185 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Ryan Helsley | p | 23.013 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Sam Hentges | P | 21.013 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| Rosell Herrera | SS | 24.288 | Colorado Rockies | Albuquerque (AAA) | Activated from disabled list |
| Carter Kieboom | ss | 19.331 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Dean Kiekhefer | RP | 28.054 | Seattle Mariners | Tacoma (AAA) | Activated from disabled list |
| Tyler Kolek | P | 21.229 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Bobby LaFromboise | RP | 31.036 | Texas Rangers | Arizona Rangers (Rk) | Activated from disabled list |
| Austin Listi | of | 23.268 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Daniel Lockhart | SS-2B | 24.269 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| Drew Lugbauer | c | 20.342 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Juan Luis | of | 21.130 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Danilo Manzueta | p | 20.194 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Evan Marshall | RP | 27.104 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) for rehab |
| Evan Marzilli | OF | 26.140 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Reese McGuire | C | 22.151 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Zach McKinstry | ss | 22.093 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Charlie Meyer | c | 24.202 | Milwaukee Brewers | Carolina (A+) | Activated from disabled list |
| Chase Mullins | p | 23.012 | Atlanta Braves | Florida (A+) | Activated from disabled list |
| Steve Nogosek | p | 22.201 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Shawn O'Malley | RF-3B | 29.216 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) for rehab |
| Samuel Ortiz | 2b | 20.361 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Matt Pare | 1B | 26.256 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Isaac Paredes | ss | 18.163 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Jose Pena | P | 26.131 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Shane Peterson | DH-LF | 29.171 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Philip Pfeifer | p | 25.016 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Ivan Pineyro | P | 25.306 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| A.J. Puckett | p | 22.065 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Henry Ramos | CF-RF | 25.107 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Matt Ramsey | P | 27.310 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Ryan Riga | p | 24.282 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Junior Rincon | P | 25.237 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Tyson Ross | SP | 30.100 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) for rehab |
| Nick Routt | P | 26.337 | Cincinnati Reds | Arizona Reds (Rk) | Activated from disabled list |
| Evy Ruibal | p | 21.306 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Yan Sanchez | ss | 20.334 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Brandon Sandoval | of | 22.037 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Michael Silva | p | 22.251 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Louis Silverio | OF | 23.228 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Forrest Snow | P | 28.213 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Michael Taylor | CF | 26.127 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) for rehab |
| Placido Torres | p | 24.075 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Touki Toussaint | P | 21.041 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Tyler Watson | p | 20.070 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Jonah Wesely | P | 22.235 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Caleb Whalen | of | 24.285 | Milwaukee Brewers | Carolina (A+) | Assigned to Carolina (A+) |
| Garrett Williams | p | 22.319 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Cole Wiper | P | 25.058 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) |
| Ryne Stanek | P | 26.005 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Brett Anderson | SP | 29.181 | | | Released by Cubs |
| Nick Ahmed | SS | 27.138 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Transferred to 60-day DL |
| Andrew McKirahan | RP | 27.173 | Cincinnati Reds | Pensacola (AA) | DL-7 Injured |
| Ben Rowen | P | 28.258 | New York Mets | Las Vegas (AAA) | Placed on temporary inactive list |
| Griffin Glaude | p | 25.116 | Toronto Blue Jays | Lansing (A) | Placed on temporary inactive list |
| Jimmy Reyes | P | 28.146 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Jordan Smith | 3B | 27.026 | Cleveland Indians | Columbus (AAA) | DL-7 Injured |
| Tyrone Taylor | OF | 23.190 | Milwaukee Brewers | Biloxi (AA) | DL-7 Injured |
| Brandon Bailey | p | 22.285 | Oakland Athletics | Stockton (A+) | DL-7 Injured |
| Casey Bloomquist | p | 23.187 | Chicago Cubs | Myrtle Beach (A+) | DL-7 Injured |
| Kyle Survance | of | 23.237 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Luke Raley | of | 22.315 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Mason Thompson | p | 19.161 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Jared Poche' | p | 22.252 | Oakland Athletics | Vermont (A-) | DL-60 Injured |
| Luis Curbelo | ss | 19.263 | Chicago White Sox | Arizona White Sox (Rk) | DL-60 Injured |
| Preston Grand Pre | ss | 22.016 | Los Angeles Dodgers | Arizona Dodgers (Rk) | DL-60 Injured |
| Ricky Mota | ss | 19.160 | | | Released by White Sox |
| Jake Baker | p | 19.049 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | DL-7 Injured |
| Brennan Price | p | 22.016 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to GCL Blue Jays (Rk) |
| Kennard McDowell | ss | 23.319 | Colorado Rockies | Grand Junction (Rk) | Signed as undrafted free agent (UNC Wilmington) |
| Joe Jimenez | P | 22.195 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
