| Scott Alexander | RP | 27.320 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) for rehab |
| Peter Alonso | if | 22.170 | New York Mets | St. Lucie (A+) | Activated from disabled list |
| Nathan Bannister | p | 23.160 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| AJ Bogucki | p | 22.024 | Washington Nationals | Hagerstown (A) | Activated from disabled list |
| Jason Bourgeois | CF | 35.142 | Chicago White Sox | Charlotte (AAA) | Activated from disabled list |
| Greg Brody | IF | 25.217 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Yoenis Cespedes | LF | 31.228 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) for rehab |
| Matt Crouse | P | 26.329 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| J.R. Davis | 2b | 22.289 | St. Louis Cardinals | Peoria (A) | Activated from disabled list |
| Alex De Goti | ss | 22.280 | Houston Astros | Quad Cities (A) | Activated from disabled list |
| Allan De San Miguel | C | 29.115 | Kansas City Royals | Northwest Arkansas (AA) | Activated from disabled list |
| Jaff Decker | CF-RF | 27.092 | Oakland Athletics | Nashville (AAA) | Activated from disabled list |
| Jake Drehoff | P | 24.355 | Boston Red Sox | Greenville (A) | Activated from disabled list |
| Tommy Edman | ss | 22.017 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Chris Ellis | P | 24.246 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| J.J. Franco | SS | 25.114 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Adonis Garcia | 3B | 32.044 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) for rehab |
| Granden Goetzman | OF | 24.193 | Tampa Bay Rays | Montgomery (AA) | Activated from disabled list |
| Chris Heston | SP | 29.046 | Los Angeles Dodgers | Oklahoma City (AAA) | Claimed off waivers from Mariners by Dodgers |
| Reilly Hovis | p | 23.211 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Jerry Keel | p | 23.242 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Justin Kelly | p | 24.034 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Matt Kent | p | 24.255 | Boston Red Sox | Salem (A+) | Reinstated to active roster |
| Corey Kluber | SP | 31.046 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) for rehab |
| Brody Koerner | p | 23.221 | New York Yankees | Tampa (A+) | Activated from disabled list |
| Rudy Martin | of | 21.116 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Jose Martinez | 1B-RF | 28.305 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) for rehab |
| James Marvel | p | 23.251 | Pittsburgh Pirates | West Virginia (A) | Activated from disabled list |
| Ryan Mason | p | 22.234 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| David Masters | SS | 24.033 | Washington Nationals | Potomac (A+) | Activated from disabled list |
| Kyle Mcgrath | P | 24.299 | San Diego Padres | San Antonio (AA) | Activated from disabled list |
| Patrick McGuff | p | 23.057 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Heiker Meneses | SS-2B | 25.330 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Yoan Moncada | 3B | 21.365 | Chicago White Sox | Charlotte (AAA) | Activated from disabled list |
| Rafael Montero | RP | 26.221 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Jairo Munoz | P | 25.288 | Tampa Bay Rays | Charlotte (A+) | Activated from disabled list |
| Harrison Musgrave | P | 25.084 | Colorado Rockies | Albuquerque (AAA) | Activated from disabled list |
| Jacob Nix | p | 21.138 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Brett Oberholtzer | SP | 27.329 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Steven Okert | RP | 25.322 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| James Paxton | SP | 28.201 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) for rehab |
| Joel Payamps | P | 23.049 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| Brandon Peterson | P | 25.246 | Los Angeles Angels | Mobile (AA) | Activated from disabled list |
| Joe Pistorese | p | 24.223 | Seattle Mariners | Modesto (A+) | Activated from disabled list |
| Lane Ratliff | P | 22.065 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Kyle Regnault | P | 28.164 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Josh Rogers | p | 22.320 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Jared Ruxer | P | 24.301 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Ariel Sandoval | OF | 21.202 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Activated from disabled list |
| Trevor Simms | p | 25.072 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Devin Smeltzer | p | 21.262 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Dwight Smith | OF | 24.212 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Robert Stock | C | 27.186 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Wilmer Torres | p | 20.360 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Cesar Valdez | SP | 32.070 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Beck Wheeler | P | 28.164 | New York Mets | Las Vegas (AAA) | Activated from disabled list |
| Donnie Hart | RP | 26.262 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Tyson Ross | SP | 30.034 | Texas Rangers | Round Rock (AAA) | Transferred to 60-day DL |
| Dallas Keuchel | SP | 29.146 | Houston Astros | Houston Astros (MLB) | Activated from DL |
| Brian McCann | C | 33.096 | Houston Astros | Houston Astros (MLB) | Activated from DL |
| Miguel Socolovich | RP | 30.306 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Designated for Assignment |
| John Brebbia | P | 26.361 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Contract purchased from minors |
| Buck Farmer | SP | 26.095 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) as 26th man |
| Tyler Danish | P | 22.256 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) as 26th man |
| Manuel Margot | CF | 22.240 | San Diego Padres | San Diego Padres (MLB) | DL-10 Strained right calf |
| Franchy Cordero | SS | 22.266 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Dillon Gee | RP | 31.028 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| AJ Griffin | SP | 29.119 | Texas Rangers | Texas Rangers (MLB) | DL-10 Left intercostal muscle strain |
| Mike Morin | RP | 26.023 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| William Cuevas | RP | 26.224 | Detroit Tigers | Toledo (AAA) | Designated for Assignment |
| Arcenio Leon | P | 30.246 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| JaCoby Jones | CF | 25.016 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Ian Kinsler | 2B | 34.338 | Detroit Tigers | Detroit Tigers (MLB) | DL-10 Strained left hamstring |
| Tyler Saladino | 2B | 27.310 | Chicago White Sox | Chicago White Sox (MLB) | DL-10 Back spasms |
| Adam Engel | IF-OF | 25.169 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Brian Johnson | SP | 26.170 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Jharel Cotton | SP | 25.128 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Jesse Hahn | SP | 27.300 | Oakland Athletics | Oakland Athletics (MLB) | DL-10 Strained right triceps |
| Adalberto Mejia | P | 23.340 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Adam Wilk | P | 29.169 | Minnesota Twins | Minnesota Twins (MLB) | Designated for Assignment |
| Aaron Hill | LF | 35.066 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Scott Kazmir | SP | 33.123 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Transferred to 60-day DL |
| Andrew Toles | LF | 25.002 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Transferred to 60-day DL |
| Josh Donaldson | 3B-DH | 31.169 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Troy Tulowitzki | SS | 32.228 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Mike Freeman | 1B | 29.296 | Atlanta Braves | Atlanta Braves (MLB) | Claimed off waivers from Mariners by Braves |
| Seth Lugo | SP | 27.190 | New York Mets | St. Lucie (A+) | Transferred to 60-day DL |
| Tyler Pill | P | 26.362 | New York Mets | New York Mets (MLB) | Contract purchased from minors |
| Austin Jackson | CF | 30.114 | Cleveland Indians | Cleveland Indians (MLB) | Activated from DL |
| Luis Sardinas | SS | 24.010 | Baltimore Orioles | Norfolk (AAA) | Outrighted to minors |
| Junior Guerra | SP | 32.130 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Activated from DL |
| Ryan Braun | LF | 33.191 | Milwaukee Brewers | Milwaukee Brewers (MLB) | DL-10 Strained left calf |
| Kyle Blanks | LF | 30.257 | | | Released by Giants |
| Dylan Covey | SP | 25.286 | Chicago White Sox | Chicago White Sox (MLB) | DL-10 Left oblique strain |
| Juan Minaya | RP | 26.250 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| David Phelps | RP | 30.229 | Miami Marlins | Miami Marlins (MLB) | Reinstated from Bereavement list |
| Rafael Bautista | RF | 24.079 | Washington Nationals | Syracuse (AAA) | DL-7 Injured |
| Chantz Mack | OF | 26.022 | | | Released by Mariners |
| Jio Mier | SS | 26.273 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Kody Kerski | P | 25.038 | | | Released by Mariners |
| Richard Rodriguez | P | 27.083 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Alex Winkelman | p | 23.107 | Houston Astros | Corpus Christi (AA) | Placed on temporary inactive list |
| B.J. Lopez | C | 22.239 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assigned to extended spring training |
| Connor Lien | OF | 23.072 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Emilio Guerrero | SS | 24.278 | Toronto Blue Jays | New Hampshire (AA) | DL-7 Injured |
| Jay Baum | IF-OF | 24.213 | | | Released by Mariners |
| Joel Fisher | C-IF | 24.138 | | | Released by Phillies |
| Jon Perrin | p | 24.003 | Milwaukee Brewers | Biloxi (AA) | DL-7 Injured |
| Justin Seager | IF | 25.011 | Seattle Mariners | Arkansas (AA) | DL-7 Injured |
| Karch Kowalczyk | IF | 26.056 | Los Angeles Dodgers | Tulsa (AA) | Placed on temporary inactive list |
| Mickey Jannis | p | 29.162 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Telvin Nash | 1B | 26.095 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Yohan Ramirez | p | 22.020 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Cody Stashak | p | 22.356 | Minnesota Twins | Fort Myers (A+) | DL-7 Injured |
| Drew Jackson | ss | 23.302 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Franklyn Kilome | P | 21.336 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Assigned to extended spring training |
| Jonny Drozd | P | 25.252 | Minnesota Twins | Fort Myers (A+) | DL-7 Injured |
| Shawon Dunston | CF | 24.110 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Tyler Frohwirth | p | 23.255 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Carlos Sanabria | p | 20.122 | Houston Astros | Houston Astros (MLB) | Assigned to extended spring training |
| Hildemaro Requena | p | 19.310 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Manuel Geraldo | ss | 20.245 | San Francisco Giants | San Francisco Giants (MLB) | Assigned to extended spring training |
| Ryan Kirby | 1b | 22.121 | San Francisco Giants | San Francisco Giants (MLB) | Assigned to extended spring training |
| Shane Carrier | of | 20.357 | Minnesota Twins | Minnesota Twins (MLB) | Assigned to extended spring training |
| Tyler Beardsley | p | 23.009 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Will Albertson | c | 22.334 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Ryan Raburn | LF | 36.039 | Washington Nationals | Washington Nationals (MLB) | Trade from White Sox to Nationals |
| Peter O'Brien | C | 26.315 | Texas Rangers | Round Rock (AAA) | Claimed off waivers from Reds by Rangers |
| Angher Cespedes | p | 22.305 | | | Released by Nationals |
| Anthony Ray | CF | 22.084 | | | Released by Cardinals |
