| Jose Antequera | ss | 21.298 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Andrew Aplin | OF | 26.065 | Seattle Mariners | Tacoma (AAA) | Traded from Astros to Mariners for player to be named later |
| Carlos Asuaje | 2B | 25.205 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Tyler Baker | C | 24.078 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Jeremy Barfield | RF | 28.317 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| T.J. Bennett | if | 24.307 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Royce Bolinger | OF | 26.286 | Texas Rangers | Frisco (AA) | Activated from disabled list |
| Zack Bowers | c | 23.223 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| J.R. Bradley | P | 24.350 | Arizona Diamondbacks | Visalia (A+) | Activated from disabled list |
| Colten Brewer | P | 24.208 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Parker Bugg | p | 22.211 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Ian Clarkin | P | 22.100 | New York Yankees | Tampa (A+) | Activated from disabled list |
| Tyler Cravy | SP | 27.316 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Matt Dean | 3B | 24.154 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Jhonathan Diaz | p | 20.254 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Felix Doubront | RP | 29.215 | Oakland Athletics | Nashville (AAA) | Activated from disabled list |
| Paolo Espino | P | 30.135 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Matt Flemer | P | 26.184 | Colorado Rockies | Albuquerque (AAA) | Reinstated to active roster |
| Arquimedes Gamboa | ss | 19.244 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Stephen Gaylor | OF | 25.234 | Atlanta Braves | Mississippi (AA) | Activated from disabled list |
| Tyler Gilbert | p | 23.154 | Philadelphia Phillies | Clearwater (A+) | Activated from disabled list |
| J.A. Happ | SP | 34.218 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) for rehab |
| Garrett Harrison | p | 23.284 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Cristian Javier | p | 20.060 | Houston Astros | Buies Creek (A+) | Assigned to Buies Creek (A+) |
| Tyler Jay | p | 23.036 | Minnesota Twins | Chattanooga (AA) | Activated from disabled list |
| Chris Jensen | P | 26.237 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Corey Kluber | SP | 31.045 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) for rehab |
| Nash Knight | 3b | 24.247 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Jeff Kobernus | cf | 28.329 | Seattle Mariners | Arkansas (AA) | Signed to Minor League Contract |
| Chris Mathewson | p | 20.364 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Seth Mejias-Brean | IF | 26.050 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Ben Meyer | p | 24.115 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Adam Morgan | RP | 27.087 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Hank Morrison | of | 23.061 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Connor Myers | of | 23.111 | Chicago Cubs | Myrtle Beach (A+) | Activated from disabled list |
| Gustavo Nunez | SS | 29.107 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Danny Ortiz | RF-LF | 27.140 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Emilio Pagan | P | 26.018 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Enoli Paredes | p | 21.240 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Carlos Perez | C | 26.210 | Los Angeles Angels | Salt Lake (AAA) | Activated from disabled list |
| Dario Pizzano | OF | 26.030 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Brooks Pounders | RP | 26.241 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Blake Quinn | p | 22.269 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Steven Reveles | if | 24.137 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Daniel Reynolds | P | 26.023 | Atlanta Braves | Mississippi (AA) | Activated from disabled list |
| Nick Rickles | C | 27.112 | Philadelphia Phillies | Reading (AA) | Traded from Nationals to Phillies |
| Jorma Rodriguez | ss | 21.061 | Cleveland Indians | Lake County (A) | Reinstated to active roster |
| Zac Rosscup | RP | 28.350 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jake Sanchez | P | 27.279 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Braeden Schlehuber | C | 29.139 | Atlanta Braves | Gwinnett (AAA) | Activated from disabled list |
| Luis Silverio | of | 21.333 | Arizona Diamondbacks | Kane County (A) | Activated from disabled list |
| Jonathan Singleton | 1B-DH | 25.250 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
| Junior Soto | of | 20.124 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Vance Tatum | p | 22.023 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Toby Thomas | SS | 23.167 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Christian Torres | p | 23.260 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Luis Villegas | C | 24.174 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Jose Vizcaino | ss | 23.050 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Jared Walker | 3B | 21.111 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Corey Walter | P | 24.287 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Gianfranco Wawoe | 2B | 22.304 | Seattle Mariners | Modesto (A+) | Assigned to Modesto (A+) |
| Rowan Wick | P | 24.197 | St. Louis Cardinals | Memphis (AAA) | Activated from disabled list |
| James McCann | C | 26.346 | Detroit Tigers | Detroit Tigers (MLB) | DL-10 Left hand laceration |
| Henry Urrutia | dh | 30.101 | | | Released by Orioles |
| Adam Liberatore | RP | 30.013 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Luis Avilan | RP | 27.310 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Sore left triceps |
| Asdrubal Cabrera | SS | 31.193 | New York Mets | New York Mets (MLB) | Activated from DL |
| Dinelson Lamet | P | 24.311 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from minors |
| Kenta Maeda | SP | 29.044 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Joc Pederson | CF | 25.034 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-7 Concussion |
| Lonnie Chisenhall | CF | 28.233 | Cleveland Indians | Cleveland Indians (MLB) | DL-7 Concussion |
| Peter O'Brien | C | 26.314 | Cincinnati Reds | Louisville (AAA) | Designated for Assignment |
| Amir Garrett | P | 25.022 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-10 Right hip inflammation |
| Jake Buchanan | SP | 27.243 | Cincinnati Reds | Cincinnati Reds (MLB) | Claimed off waivers from Cubs by Reds |
| Chris Marrero | LF | 28.327 | | | Signed with Orix (Japan) |
| Gregory Polanco | LF | 25.254 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Activated from DL |
| Jeanmar Gomez | RP | 28.235 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Daniel Wright | RP | 26.052 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Rob Refsnyder | LF | 26.060 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Jacoby Ellsbury | CF | 33.257 | New York Yankees | New York Yankees (MLB) | DL-7 Concussion |
| Jumbo Diaz | RP | 33.088 | Tampa Bay Rays | Tampa Bay Rays (MLB) | DL-10 Right arm fatigue |
| Tommy Hunter | RP | 30.326 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Activated from DL |
| Matt Wisler | SP | 24.255 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Josh Collmenter | RP | 31.107 | Atlanta Braves | Atlanta Braves (MLB) | Designated for Assignment |
| Tim Dillard | P | 33.311 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Allan De San Miguel | C | 29.114 | Kansas City Royals | Northwest Arkansas (AA) | DL-7 Injured |
| Aneury Tavarez | 2B | 25.041 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Bradley Roney | 3B | 24.266 | Atlanta Braves | Mississippi (AA) | DL-7 Injured |
| Carlos Arroyo | OF | 23.331 | Texas Rangers | Down East (A+) | DL-7 Injured |
| Scott Barlow | P | 24.158 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Steven Ridings | p | 23.086 | Seattle Mariners | Seattle Mariners (MLB) | Assigned to extended spring training |
| Brandon Peterson | P | 25.245 | Los Angeles Angels | Mobile (AA) | DL-7 Injured |
| Jairo Munoz | P | 25.287 | Tampa Bay Rays | Charlotte (A+) | DL-7 Injured |
| Keegan Akin | p | 22.054 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (Rk) |
| Leon Byrd | 2b | 23.087 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Matt Kent | p | 24.254 | Boston Red Sox | Salem (A+) | Placed on temporary inactive list |
| Narciso Crook | RF | 21.318 | Cincinnati Reds | Daytona (A+) | DL-7 Injured |
| Sarkis Ohanian | p | 23.292 | Cincinnati Reds | Daytona (A+) | DL-7 Injured |
| Tommy Thorpe | P | 24.247 | Chicago Cubs | Myrtle Beach (A+) | DL-7 Injured |
| Yunior Montero | P | 23.290 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Assigned to extended spring training |
| Alfredo Gonzalez | c | 21.163 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (Rk) |
| C.J. Chatham | ss | 22.154 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Darwinzon Hernandez | p | 20.159 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Jordan Desguin | p | 23.207 | Milwaukee Brewers | Wisconsin (A) | DL-7 Injured |
| Luis Castro | 3B | 21.249 | Colorado Rockies | Asheville (A) | DL-7 Injured |
| Samuel Pastrone | p | 19.331 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| Tayler Saucedo | p | 23.341 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Assigned to extended spring training |
| Bryan Mata | p | 18.022 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
