| Tyler Baker | C | 24.074 | Arizona Diamondbacks | Kane County (A) | Activated from disabled list |
| David Berg | p | 24.054 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Arnaldo Berrios | CF | 21.127 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Shane Billings | of | 22.158 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Akeem Bostick | P | 22.017 | Houston Astros | Corpus Christi (AA) | Activated from disabled list |
| Ronald Bueno | SS | 24.229 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Joey Butler | DH | 31.070 | Washington Nationals | Syracuse (AAA) | Activated from disabled list |
| Johan Camargo | ss | 23.159 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Justin Camp | p | 24.004 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Leonel Campos | RP | 29.309 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Elio Castillo | 1B | 23.081 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Garrett Cooper | IF | 26.147 | Milwaukee Brewers | Colorado Springs (AAA) | Activated from disabled list |
| Travis D'Arnaud | C | 28.100 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) for rehab |
| Keury De la cruz | CF | 25.175 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Eduardo de Oleo | C | 24.116 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Odrisamer Despaigne | RP | 30.047 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Connor Eller | p | 23.118 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Caleb Ferguson | P | 20.323 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Aaron Fossas | p | 24.261 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Jace Fry | P | 23.316 | Chicago White Sox | Birmingham (AA) | Activated from disabled list |
| Tyler Goeddel | LF | 24.213 | Cincinnati Reds | Pensacola (AA) | Activated from disabled list |
| Ismael Guillon | P | 25.098 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Andrew Guillotte | 2b | 24.052 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Aaron Hill | LF | 35.061 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) for rehab |
| Travis Hissong | P | 25.307 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Chris Huffman | P | 24.177 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Patrick Johnson | P | 28.280 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Tommy La Stella | 3B | 28.110 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Carlos Martinez | C | 22.019 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Jose Medina | P | 20.269 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Thomas Milone | OF | 22.115 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Jonathan Oquendo | SS | 21.061 | Milwaukee Brewers | Carolina (A+) | Assigned to Carolina (A+) |
| Mitchell Osnowitz | P | 25.324 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Dillon Overton | RP | 25.278 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Steve Perakslis | P | 26.126 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Luis Pino | P | 22.198 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Patrick Riehl | p | 23.002 | Cincinnati Reds | Dayton (A) | Activated from disabled list |
| Eric Ruth | P | 26.237 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Dwight Smith | OF | 24.207 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Ryan Thompson | P | 24.329 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Nik Turley | P | 27.252 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Julio Urias | SP | 20.282 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Jon Wandling | P | 24.358 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Juan Yepez | 3b | 19.091 | St. Louis Cardinals | Peoria (A) | Traded from Braves to Cardinals for Matt Adams |
| Adalberto Mejia | P | 23.335 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Miguel Almonte | RP | 24.047 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| T.J. McFarland | RP | 27.347 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Taijuan Walker | SP | 24.281 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-10 Blister on right index finger |
| Ian Kennedy | SP | 32.153 | Kansas City Royals | Kansas City Royals (MLB) | Activated from DL |
| Adalberto Mondesi | 2B | 21.299 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Alex Gordon | LF | 33.101 | Kansas City Royals | Kansas City Royals (MLB) | Placed on paternity leave list |
| Dan Vogelbach | 1B | 24.155 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Josh Ravin | RP | 29.121 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Carter Capps | RP | 26.287 | San Diego Padres | El Paso (AAA) | Transferred to 60-day DL |
| Chase D'Arnaud | LF | 30.120 | San Diego Padres | San Diego Padres (MLB) | Claimed off waivers from Red Sox by Padres |
| Ryan Braun | LF | 33.186 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Activated from DL |
| Brandon Workman | RP | 28.281 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Chris Heston | SP | 29.041 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Paul Janish | SS | 34.221 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Ryan Flaherty | SS | 30.298 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Right shoulder tendinitis |
| Jason Heyward | RF-CF | 27.285 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Dylan Floro | P | 26.145 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Anthony Recker | C | 33.266 | Atlanta Braves | Gwinnett (AAA) | Designated for Assignment |
| Juan Centeno | C | 27.186 | Houston Astros | Houston Astros (MLB) | Contract purchased from minors |
| Brian McCann | C | 33.091 | Houston Astros | Houston Astros (MLB) | DL-7 Concussion |
| Al Alburquerque | RP | 30.345 | Kansas City Royals | Kansas City Royals (MLB) | Designated for Assignment |
| Jake Junis | RP | 24.247 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Aaron Nola | SP | 23.351 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Bruce Maxwell | C | 26.152 | Oakland Athletics | Nashville (AAA) | DL-7 Injured |
| Paulo Orlando | RF | 31.201 | Kansas City Royals | Omaha (AAA) | DL-7 Fractured shin |
| Andres Santiago | P | 27.207 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Elvis Rubio | OF | 22.323 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Jacob Rhame | P | 24.066 | Los Angeles Dodgers | Oklahoma City (AAA) | DL-7 Injured |
| Nick Routt | P | 26.266 | Cincinnati Reds | Louisville (AAA) | DL-7 Injured |
| Trevor Simms | p | 25.067 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assigned to extended spring training |
| Eliezer Alvarez | 2B-3B | 22.218 | St. Louis Cardinals | Springfield (AA) | DL-7 Injured |
| Elvin Soto | C | 25.099 | Colorado Rockies | Grand Junction (Rk) | Assigned to Grand Junction (Rk) |
| Alex Katz | p | 22.221 | Baltimore Orioles | Baltimore Orioles (MLB) | Traded from White Sox to Orioles for intl bonus slots |
| Blake Quinn | p | 22.265 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Assigned to extended spring training |
| Chris Mathewson | p | 20.360 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Assigned to extended spring training |
| Kyri Washington | of | 22.314 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Adam McCreery | P | 24.141 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Enoli Paredes | p | 21.236 | Houston Astros | Houston Astros (MLB) | Assigned to extended spring training |
| Frederis Parra | P | 22.211 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Gabriel Cancel | ss | 20.164 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| James Marvel | p | 23.246 | Pittsburgh Pirates | West Virginia (A) | DL-7 Injured |
| Joey Wentz | p | 19.227 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Ricardo Cespedes | of | 19.270 | New York Mets | Columbia (A) | DL-7 Injured |
| Stephen Alemais | ss | 22.039 | Pittsburgh Pirates | West Virginia (A) | DL-7 Injured |
| Vance Tatum | p | 22.019 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Blake Lalli | 1B | 34.009 | | | Released by Braves |
| Carlos Perez | C | 26.206 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Orlando Calixte | SS | 25.108 | San Francisco Giants | Sacramento (AAA) | DL-7 Injured |
| Steven Moya | RF | 25.256 | Detroit Tigers | Toledo (AAA) | DL-7 Injured |
| Zach Walters | SS | 27.258 | | | Released by Reds |
| Carlos Moncrief | RF | 28.199 | San Francisco Giants | Sacramento (AAA) | Placed on temporary inactive list |
| Matt Lujan | P | 28.271 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Johneshwy Fargas | CF | 22.157 | San Francisco Giants | San Jose (A+) | DL-7 Injured |
| Devin Smeltzer | p | 21.257 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Emilio Gustave | of | 22.115 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Assigned to extended spring training |
| Justin Maese | p | 20.209 | Toronto Blue Jays | Lansing (A) | Placed on temporary inactive list |
| Charcer Burks | CF | 22.073 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Kent Emanuel | P | 24.351 | Houston Astros | Corpus Christi (AA) | Placed on temporary inactive list |
| Cole Anderson | of | 20.103 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
