| Vance Worley | RP | 29.190 | Miami Marlins | Miami Marlins (MLB) | Signed to Minor League Contract |
| Luke Maile | C | 26.055 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Designated for Assignment |
| Brett Wallace | 1B | 30.219 | | | Released by Padres |
| Jose Osuna | 1B-LF | 24.111 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Assigned to minors |
| Glenn Sparkman | P | 24.326 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Fractured right thumb |
| Bo Schultz | RP | 31.189 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Torn right UCL |
| Dalton Pompey | CF | 24.112 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Concussion |
| Roberto Osuna | RP | 22.054 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Cervical spasm |
| Melvin Upton | LF-CF | 32.224 | | | Released by Blue Jays |
| Jarrod Saltalamacchia | C | 31.335 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from minors |
| Dominic Leone | RP | 25.159 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from minors |
| Mike Bolsinger | SP | 29.064 | Toronto Blue Jays | Buffalo (AAA) | Designated for Assignment |
| Oliver Drake | RP | 30.079 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Craig Gentry | LF-RF | 33.125 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Gabriel Ynoa | P | 23.311 | Baltimore Orioles | Baltimore Orioles (MLB) | Assigned to minors |
| Jayson Aquino | RP | 24.131 | Baltimore Orioles | Baltimore Orioles (MLB) | Assigned to minors |
| Anthony Santander | OF | 22.165 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Right elbow inflammation |
| Wade Miley | SP | 30.140 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Illness |
| Chris Tillman | SP | 28.352 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Right shoulder soreness |
| Daniel Stumpf | P | 26.088 | | | Granted free agency |
| Daniel Stumpf | P | 26.088 | Detroit Tigers | Detroit Tigers (MLB) | Signed to 1-year contract for 2017-2017 ($0m) and assigned to minors |
| Micah Johnson | LF | 26.105 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Fractured left wrist |
| Armando Rivero | P | 29.061 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Strained right shoulder |
| Mauricio Cabrera | RP | 23.192 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Right elbow strain |
| Anthony Recker | C | 33.217 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| David Dahl | LF | 23.001 | Colorado Rockies | Colorado Rockies (MLB) | DL-10 Stress reaction in ribcage |
| Ian Desmond | CF | 31.194 | Colorado Rockies | Colorado Rockies (MLB) | DL-10 Fractured left hand |
| Tom Murphy | C | 25.365 | Colorado Rockies | Colorado Rockies (MLB) | DL-10 Hairline fracture, right forearm |
| Chris Rusin | RP | 30.162 | Colorado Rockies | Colorado Rockies (MLB) | DL-10 Strained right oblique |
| Chad Qualls | RP | 38.228 | Colorado Rockies | Colorado Rockies (MLB) | DL-10 Right forearm tightness |
| Jairo Diaz | RP | 25.311 | Colorado Rockies | Colorado Rockies (MLB) | DL-10 Recovery from right elbow surgery |
| Miguel Castro | P | 22.099 | Colorado Rockies | Albuquerque (AAA) | Designated for Assignment |
| Kyle Freeland | SP | 23.323 | Colorado Rockies | Colorado Rockies (MLB) | Contract purchased from minors |
| David Wright | 3B | 34.103 | New York Mets | New York Mets (MLB) | DL-10 Cervical disc herniation |
| Brandon Nimmo | CF | 24.006 | New York Mets | New York Mets (MLB) | DL-10 Strained right hamstring |
| Steven Matz | SP | 25.309 | New York Mets | New York Mets (MLB) | DL-10 Left elbow irritation |
| Seth Lugo | SP | 27.136 | New York Mets | New York Mets (MLB) | DL-10 Partial tear in right elbow UCL |
| Juan Lagares | CF | 28.016 | New York Mets | New York Mets (MLB) | DL-10 Left oblique strain |
| Ty Kelly | LF | 28.256 | New York Mets | New York Mets (MLB) | Contract purchased from minors |
| Anthony Swarzak | RP | 31.204 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Geovany Soto | C | 34.072 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Cody Asche | DH | 26.276 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Charlie Tilson | CF-LF | 24.121 | Chicago White Sox | Chicago White Sox (MLB) | DL-10 Stress reaction, right foot |
| Carlos Rodon | SP | 24.113 | Chicago White Sox | Chicago White Sox (MLB) | DL-10 Left biceps bursitis |
| Juan Minaya | RP | 26.196 | Chicago White Sox | Chicago White Sox (MLB) | DL-10 Right abdominal strain |
| Tyler Cravy | SP | 27.263 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Assigned to minors |
| Jared Hughes | RP | 31.272 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Signed to 1-year contract for 2017-2017 ($0.95m) |
| Tanner Scheppers | RP | 30.075 | Texas Rangers | Texas Rangers (MLB) | DL-10 Sore left abdominal muscle |
| Tyson Ross | SP | 29.346 | Texas Rangers | Texas Rangers (MLB) | DL-10 Recovery from thoracic outlet surgery |
| Brett Nicholas | 1B | 28.258 | Texas Rangers | Texas Rangers (MLB) | DL-10 Torn meniscus, left knee |
| Adrian Beltre | 3B | 37.361 | Texas Rangers | Texas Rangers (MLB) | DL-10 Right calf tightness |
| Hanser Alberto | 3B | 24.167 | Texas Rangers | Texas Rangers (MLB) | DL-10 Right shoulder tightness |
| Andrew Cashner | SP | 30.203 | Texas Rangers | Texas Rangers (MLB) | DL-10 Right biceps tendinitis |
| Chi Chi Gonzalez | RP | 25.078 | Texas Rangers | Texas Rangers (MLB) | DL-60 Partially torn UCL, right elbow |
| Andre Ethier | LF | 34.357 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Herniated disc |
| Scott Kazmir | SP | 33.069 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Sore hip |
| Brock Stewart | SP | 25.182 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Right shoulder tendinitis |
| Josh Ravin | RP | 29.072 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Strained right groin |
| Pedro Baez | RP | 29.022 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Right thumb strain |
| Tim Cooney | SP | 26.104 | | | Released by Indians |
| Lonnie Chisenhall | RF | 28.180 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Right shoulder sprain |
| Jason Kipnis | 2B | 29.365 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Right shoulder inflammation |
| Cody Anderson | RP | 26.200 | Cleveland Indians | Cleveland Indians (MLB) | DL-60 Tommy John Surgery |
| Yadier Molina | C | 34.263 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Signed to 3-year contract for 2018-2020 ($60m) 20--20--20 [Extension] |
| Peter Moylan | RP | 38.121 | Kansas City Royals | Kansas City Royals (MLB) | Contract purchased from minors |
| Hunter Dozier | RF | 25.224 | Kansas City Royals | Kansas City Royals (MLB) | DL-60 left oblique strain |
| Jorge Soler | LF | 25.037 | Kansas City Royals | Kansas City Royals (MLB) | DL-10 Strained left oblique |
| Martin Prado | 3B | 33.158 | Miami Marlins | Miami Marlins (MLB) | DL-10 Strained right hamstring |
| Jeff Locke | RP | 29.134 | Miami Marlins | Miami Marlins (MLB) | DL-10 Left biceps tendinitis |
| Odrisamer Despaigne | RP | 29.364 | Miami Marlins | Miami Marlins (MLB) | DL-10 Strained left oblique |
| Tyler Moore | 1B | 30.062 | Miami Marlins | Miami Marlins (MLB) | Contract purchased from minors |
| Joe Ross | SP | 23.316 | Washington Nationals | Washington Nationals (MLB) | Assigned to minors |
| Kennys Vargas | 1B | 26.244 | Minnesota Twins | Minnesota Twins (MLB) | Assigned to minors |
| Chris Gimenez | C | 34.096 | Minnesota Twins | Minnesota Twins (MLB) | Contract purchased from minors |
| Glen Perkins | CL | 34.031 | Minnesota Twins | Minnesota Twins (MLB) | DL-60 Recovery from left shoulder surgery |
| Devin Mesoraco | C | 28.287 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-10 recovery from right hip surgery |
| Nefi Ogando | RP | 27.303 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-10 Right hand strain |
| Austin Brice | RP | 24.287 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-10 Ulnar neuritis, right elbow |
| Patrick Kivlehan | RF | 27.101 | Cincinnati Reds | Cincinnati Reds (MLB) | Contract purchased from minors |
| Nick Travieso | P | 23.061 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-60 Right shoulder inflammation |
| Anthony DeSclafani | SP | 26.349 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-10 Sprained UCL right elbow |
| Roberto Perez | C | 28.100 | Cleveland Indians | Cleveland Indians (MLB) | Signed to 4-year contract for 2017-2020 ($9m) 0.55--1.5--2.5--3.5 Club options for 2021-2022 5.5--7 $500k signing bonus |
| Chris Marrero | LF | 28.274 | San Francisco Giants | San Francisco Giants (MLB) | Contract purchased from minors |
| Aaron Hill | LF | 35.012 | San Francisco Giants | San Francisco Giants (MLB) | Contract purchased from minors |
| Neil Ramirez | RP | 27.312 | San Francisco Giants | San Francisco Giants (MLB) | Contract purchased from minors |
| Mac Williamson | OF | 26.261 | San Francisco Giants | San Francisco Giants (MLB) | DL-10 Strained left quad |
| Will Smith | RP | 27.266 | San Francisco Giants | San Francisco Giants (MLB) | DL-60 Left elbow surgery |
| Trevor Brown | C | 25.139 | San Francisco Giants | San Francisco Giants (MLB) | DL-10 Sprained right ankle |
| Rio Ruiz | 3B | 22.315 | Atlanta Braves | Atlanta Braves (MLB) | Assigned to minors |
| Zach Eflin | SP | 22.359 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-10 Right and left knee tendinitis |
| Tyler Austin | 1B | 25.209 | New York Yankees | New York Yankees (MLB) | DL-60 Fractured left ankle |
| Pete Kozma | SS | 28.356 | New York Yankees | New York Yankees (MLB) | Contract purchased from minors |
| Jerry Keel | p | 23.188 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Anthony Marks | of | 22.352 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Ray Black | P | 26.280 | San Francisco Giants | San Francisco Giants (MLB) | Designated for Assignment |
| Danny Winkler | P | 27.059 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Recovery from elbow surgery |
