| Alexi Amarista | SS | 27.101 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Buddy Baumann | P | 28.220 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Edwin Escobar | RP | 24.085 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Donnie Hart | P | 25.313 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Anthony Recker | C | 32.322 | Atlanta Braves | Atlanta Braves (MLB) | Contract purchased from minors |
| Tyler Flowers | C | 30.173 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Fractured left hand |
| Nick Tepesch | SP | 27.277 | Oakland Athletics | Nashville (AAA) | Designated for Assignment |
| Edward Mujica | RP | 32.067 | Kansas City Royals | Kansas City Royals (MLB) | Signed to Minor League Contract |
| Ryon Healy | 1B-DH | 24.188 | Oakland Athletics | Oakland Athletics (MLB) | Contract purchased from minors |
| Yefri Perez | SS | 25.142 | Miami Marlins | Miami Marlins (MLB) | Recalled from Jacksonville (AA) |
| Kevin Kiermaier | CF | 26.085 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Activated from DL |
| Kevin Siegrist | RP | 26.361 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Activated from DL |
| Joe Beimel | RP | 39.088 | | | Released by Royals |
| David Ross | C | 39.119 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Trevor Cahill | RP | 28.137 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Right patellar tendinitis |
| Clayton Richard | RP | 32.308 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Tyler Collins | RF | 26.040 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Carson Fulmer | p | 22.215 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Justin Morneau | DH | 35.062 | Chicago White Sox | Chicago White Sox (MLB) | Activated from DL |
| Eduardo Rodriguez | SP | 23.100 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Jake Diekman | RP | 29.176 | Texas Rangers | Texas Rangers (MLB) | DL-15 Lacerated left index finger |
| Derek Holland | SP | 29.280 | Texas Rangers | Texas Rangers (MLB) | Transferred to 60-day DL |
| Keone Kela | RP | 23.091 | Texas Rangers | Texas Rangers (MLB) | Activated from DL |
| Joel Peralta | RP | 40.115 | | | Refused minor league assignment, declared free agent |
| Mayobanex Acosta | C | 28.239 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Carl Anderson | OF-P | 23.318 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Andrew Barbosa | P | 28.241 | New York Mets | Gulf Coast Mets (Rk) | Activated from disabled list |
| Daniel Barrios | 2b | 21.089 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Josh Bell | RF | 23.336 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Martin Cervenka | C | 23.347 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Li-Jen Chu | C | 22.125 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Vince Conde | IF | 22.276 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Hank Conger | C | 28.169 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Jonathon Crawford | P | 24.258 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Austin DeCarr | P | 21.124 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Yusniel Diaz | of | 19.282 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Activated from disabled list |
| Riley Drongesen | c | 24.048 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Jhoan Duran | p | 18.189 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Max Duval | p | 25.092 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Pedro Echemendia | p | 25.032 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Caleb Ferguson | P | 20.014 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Cole Figueroa | 3B | 29.016 | Miami Marlins | New Orleans (AAA) | Signed to 1-year contract for 2016-2016 ($0m) |
| Junior Flores | p | 21.276 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Mike Ford | P | 24.012 | New York Yankees | Staten Island (A-) | Activated from disabled list |
| Junior Garcia | P | 20.289 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Reed Garrett | P | 23.195 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Derian Gonzalez | p | 21.166 | St. Louis Cardinals | Peoria (A) | Activated from disabled list |
| Manuel Guzman | 2B | 21.156 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Hunter Harvey | P | 21.219 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Joe Harvey | P | 24.189 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Brandon Hicks | SS | 30.305 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Neil Holland | P | 27.336 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Chase Huchingson | P | 27.093 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Chris Iriart | 1b | 21.282 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Chase Jensen | SS | 25.168 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Mike King | p | 21.052 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Nick Kingham | P | 24.251 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Adam Kolarek | P | 27.183 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| George Kottaras | c | 33.061 | Atlanta Braves | Gwinnett (AAA) | Signed to Minor League Contract |
| Mark Laird | of | 23.109 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Mitch Lambson | P | 25.361 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Jack Leathersich | RP | 26.002 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Jose Leclerc | P | 22.209 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Stuart Levy | c | 23.329 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Domingo Leyba | 2B | 20.309 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Sicnarf Loopstok | C | 23.081 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Eduar Lopez | P | 21.145 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Cory Luebke | RP | 31.134 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Kenny Mathews | P | 22.344 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Jayson McKinley | p | 22.179 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Alex Monsalve | C | 24.085 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Adam Moore | C | 32.069 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Edward Mujica | RP | 32.067 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Tommy Nance | p | 25.119 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Chris Narveson | RP | 34.208 | Miami Marlins | New Orleans (AAA) | Activated from disabled list |
| Zach Nuding | P | 26.109 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Andy Paz | C | 23.192 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Richelson Pena | P | 22.290 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Brooks Pounders | P | 25.293 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Christian Powell | P | 25.013 | Houston Astros | Gulf Coast Astros (Rk) | Activated from disabled list |
| Josh Prevost | P | 24.183 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Alex Reyes | P | 21.321 | St. Louis Cardinals | Memphis (AAA) | Reinstated to active roster |
| Jo-Jo Reyes | P | 31.238 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Jason Richman | p | 22.274 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Niuman Romero | SS | 31.173 | New York Mets | Las Vegas (AAA) | Activated from disabled list |
| Eduard Rosillo | p | 22.206 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Mark Sappington | P | 25.241 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Hector Silvestre | P | 23.214 | Washington Nationals | Potomac (A+) | Activated from disabled list |
| Devon Stewart | p | 23.202 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Elias Torres | OF | 24.145 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Casey Turgeon | SS | 23.291 | St. Louis Cardinals | Palm Beach (A+) | Activated from disabled list |
| Spencer Turnbull | P | 23.301 | Detroit Tigers | West Michigan (A) | Activated from disabled list |
| A.J. Vanegas | P | 23.334 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Activated from disabled list |
| Ildemaro Vargas | SS | 25.000 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Gerwuins Velazco | C | 24.283 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Victor Veliz | P | 22.283 | Oakland Athletics | Stockton (A+) | Activated from disabled list |
| David Whitehead | P | 24.086 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Tom Windle | P | 24.128 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Josh Zeid | RP | 29.114 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Carson Blair | C | 26.271 | | | Released by Athletics |
| Justin De Fratus | RP | 28.269 | | | Released by Rangers |
| Kanekoa Texeira | P | 30.160 | Atlanta Braves | Gwinnett (AAA) | DL-7 Injured |
| Rico Noel | CF | 27.186 | Los Angeles Dodgers | Oklahoma City (AAA) | DL-7 Injured |
| Ross Detwiler | RP | 30.132 | Cleveland Indians | Columbus (AAA) | Placed on temporary inactive list |
| Sam LeCure | RP | 32.073 | Los Angeles Dodgers | Oklahoma City (AAA) | DL-7 Injured |
| Tim Dillard | P | 32.363 | Milwaukee Brewers | Colorado Springs (AAA) | DL-7 Injured |
| Aaron Judge | OF | 24.081 | New York Yankees | Scranton/Wilkes-Barre (AAA) | DL-7 Injured |
| Matt Flemer | P | 25.236 | Colorado Rockies | Albuquerque (AAA) | Placed on temporary inactive list |
| Vimael Machin | ss | 22.294 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Brandon Alger | P | 25.012 | | | Released by Padres |
| Mason Smith | CF | 21.122 | | | Released by Padres |
| Michael Johnson | P | 25.194 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Travis Harrison | 3B | 23.272 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Joe Chavez | ss | 23.020 | | | Announced retirement |
| Max Pentecost | C | 23.128 | Toronto Blue Jays | Lansing (A) | Placed on temporary inactive list |
| Sean Reid-Foley | P | 20.321 | Toronto Blue Jays | Dunedin (A+) | Placed on temporary inactive list |
| Cameron Palmer | p | 24.226 | | | Released by Dodgers |
| Cristian Gomez | SS | 20.187 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Garrett Harrison | p | 22.336 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| J.J. Franco | SS | 24.165 | Chicago White Sox | Kannapolis (A) | DL-7 Injured |
| Jordan Hillyer | p | 22.297 | | | Released by Marlins |
| Pedro Payano | p | 21.292 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Jansiel Rivera | of | 17.322 | Seattle Mariners | Dominican Mariners (Rk) | Assigned to DSL Mariners (Rk) |
| Jose Sotillo | of | 20.064 | San Diego Padres | Dominican Padres (Rk) | Assigned to DSL Padres (Rk) |
| Rafael Ordaz | p | 21.149 | Tampa Bay Rays | Gulf Coast Rays (Rk) | DL-60 Injured |
| Kevin Santiago | ss | 18.291 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed out of draft (Miami-Dade) |
| Matt Swarmer | p | 22.294 | Chicago Cubs | Arizona Cubs (Rk) | Signed out of draft (Kutztown) |
| Thomas Jones | of | 18.219 | Miami Marlins | Gulf Coast Marlins (Rk) | Signed out of draft (South Carolina HS) |
| Brayan Hernandez | of | 18.308 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to AZL Mariners (Rk) |
| Duncan Robinson | p | 22.223 | Chicago Cubs | Arizona Cubs (Rk) | Signed out of draft (Dartmouth) |
| Hunter Wells | p | 21.055 | Miami Marlins | Gulf Coast Marlins (Rk) | Signed out of draft (Gonzaga) |
| Jordan Sheffield | p | 21.045 | Los Angeles Dodgers | Ogden (Rk) | Signed out of draft (Vanderbilt) |
| Zach McKinstry | ss | 21.078 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Signed out of draft (Central Michigan) |
| Miguel Sanchez | p | 20.232 | Oakland Athletics | Arizona Athletics (Rk) | Assigned to AZL Athletics (Rk) |
