| Chi Chi Gonzalez | RP | 24.164 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Eric Surkamp | RP | 28.347 | Oakland Athletics | Nashville (AAA) | Designated for Assignment |
| Nick Tepesch | SP | 27.258 | Oakland Athletics | Oakland Athletics (MLB) | Claimed off waivers from Dodgers by Athletics |
| Ike Davis | 1B | 29.097 | New York Yankees | New York Yankees (MLB) | Outrighted to minors |
| Joel Peralta | RP | 40.096 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| Jeremy Guthrie | RP | 37.080 | Miami Marlins | Miami Marlins (MLB) | Signed to Minor League Contract |
| Steven Delabar | RP | 32.346 | | | Signed with Hiroshima (Japan) |
| Mauricio Cabrera | RP | 22.278 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Mississippi (AA) |
| Alexi Ogando | RP | 32.266 | Atlanta Braves | Atlanta Braves (MLB) | Designated for Assignment |
| Danny Farquhar | RP | 29.130 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Ryan Webb | RP | 30.142 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Designated for Assignment |
| Rafael Martin | RP | 32.042 | Washington Nationals | Washington Nationals (MLB) | Recalled from Syracuse (AAA) |
| Jumbo Diaz | RP | 32.121 | Cincinnati Reds | Cincinnati Reds (MLB) | Recalled from Louisville (AAA) |
| Mike Miller | IF | 26.273 | Boston Red Sox | Boston Red Sox (MLB) | Contract purchased from minors |
| Ryan Tepera | RP | 28.237 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Vincent Velasquez | SP | 24.020 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Curtis Partch | RP | 29.134 | Pittsburgh Pirates | Indianapolis (AAA) | Designated for Assignment |
| Chad Kuhl | P | 23.290 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Contract purchased from minors |
| Stephen Strasburg | SP | 27.342 | Washington Nationals | Washington Nationals (MLB) | DL-15 Upper back strain |
| Cory Luebke | RP | 31.115 | | | Released by Pirates |
| J.C. Ramirez | SP | 27.315 | Los Angeles Angels | Los Angeles Angels (MLB) | Claimed off waivers from Reds by Angels |
| Bo Schultz | RP | 30.275 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Gavin Floyd | RP | 33.151 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Torn right lat muscle |
| Luis Cessa | P | 24.063 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Andrew Bellatti | RP | 24.327 | Tampa Bay Rays | Durham (AAA) | Outrighted to minors |
| Bryan Abreu | p | 19.066 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| AJ Achter | RP | 27.304 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Randy Alcantara | p | 19.230 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Sergio Alcantara | SS | 19.352 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Nick Andros | p | 23.218 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Elvis Araujo | RP | 24.348 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| David Armendariz | OF | 24.310 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Claudio Bautista | | 22.210 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Bryce Beeler | 1B | 23.110 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Brennan Boesch | LF | 31.076 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Buddy Borden | P | 24.059 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Chris Bostick | SS-2B | 23.095 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Ryan Brinley | p | 23.079 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Billy Buckner | RP | 32.305 | Arizona Diamondbacks | Mobile (AA) | Activated from disabled list |
| Zack Burdi | p | 21.110 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Erlin Cerda | 3b | 22.053 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Alex Claudio | RP | 24.148 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Zach Collier | CF | 25.292 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Gerardo Concepcion | P | 24.118 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jacob Constante | P | 22.097 | Cincinnati Reds | Dayton (A) | Activated from disabled list |
| Nestor Cortes | P | 21.199 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Keith Couch | P | 26.234 | Boston Red Sox | Portland (AA) | Reinstated to active roster |
| William Cuevas | P | 25.256 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Ike Davis | 1B | 29.097 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Austin DeCarr | P | 21.105 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Chris Denorfia | LF | 35.347 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) |
| Carlos Diaz | ss | 23.224 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Robbie Dickey | P | 22.082 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Joel Effertz | P | 25.273 | Miami Marlins | Gulf Coast Marlins (Rk) | Activated from disabled list |
| Randy Encarnacion | OF | 21.331 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Tim Federowicz | C | 28.327 | Chicago Cubs | Iowa (AAA) | Outrighted to minors |
| Grayson Garvin | P | 26.243 | Tampa Bay Rays | Montgomery (AA) | Activated from disabled list |
| Chad Girodo | RP | 25.141 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Carlos Hernandez | p | 20.140 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| Dalier Hinojosa | RP | 30.137 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) for rehab |
| Jacob Howell | p | 20.323 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Chad Jenkins | RP | 28.188 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Jake Johansen | P | 25.155 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Pierce Johnson | P | 25.048 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Tyler Krieger | ss | 22.162 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Angelo La Bruna | 1b | 24.073 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Trey Lambert | P | 25.022 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Logan Landon | of | 23.130 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Ryan Leonards | SS | 24.341 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Sam Lewis | P | 24.262 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Adam Loewen | RP | 32.079 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Sicnarf Loopstok | C | 23.062 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Reynaldo Lopez | P | 22.174 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Jorge Marban | P | 27.204 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Yeison Medina | P | 23.268 | St. Louis Cardinals | Johnson City (Rk) | Assigned to Johnson City (Rk) |
| Yoervis Medina | RP | 27.335 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Francisco Mejia | | 20.244 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Danny Mendick | ss | 22.272 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Angel Miguel | ss | 26.087 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Alex Monsalve | C | 24.066 | Cleveland Indians | Lynchburg (A+) | Activated from disabled list |
| Phil Morse | p | 22.035 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Jose Nin | p | 21.007 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Geury Ortiz | p | 21.036 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Nick Pasquale | P | 25.243 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Noah Perio | 2B | 24.226 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Jake Peter | IF | 23.083 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Luke Raley | of | 21.281 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Reid Redman | IF | 27.217 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Junior Rincon | P | 24.203 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Victor Robles | of | 19.039 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Luigi Rodriguez | CF | 23.226 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Daniel Salters | c | 23.142 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Gonzalo Sanudo | P | 24.169 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Max Schrock | ss | 21.258 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Kurt Spomer | P | 26.352 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Craig Stammen | RP | 32.110 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Andrew Stevenson | of | 22.026 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Ryan Strausborger | CF | 28.115 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Trent Szkutnik | P | 22.310 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Darien Tubbs | of | 21.152 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Joey Wagman | P | 24.338 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Drew Ward | 3B | 21.214 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Spenser Watkins | P | 23.304 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Grant Watson | p | 22.360 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Boone Whiting | P | 26.311 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Enmanuel Zabala | OF | 21.271 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Brian Matusz | RP | 29.136 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Chris Narveson | RP | 34.189 | Miami Marlins | New Orleans (AAA) | DL-7 Injured |
| Scott Barnes | RP | 28.296 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Lewis Brinson | OF | 22.050 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Adam Parks | P | 23.260 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Evan Van Hoosier | 2B | 22.185 | Texas Rangers | Texas Rangers (MLB) | Assigned to extended spring training |
| Luis Silva | 2b | 20.363 | Texas Rangers | Frisco (AA) | Placed on temporary inactive list |
| Nick Sarianides | P | 26.302 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Raywilly Gomez | C | 26.153 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Sam Wolff | P | 25.074 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Artie Lewicki | P | 24.080 | Detroit Tigers | Lakeland (A+) | DL-7 Injured |
| DJ Davis | OF | 21.337 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Tyler Davis | p | 23.173 | Texas Rangers | High Desert (A+) | Placed on temporary inactive list |
| Tyler Ford | P | 24.290 | | | Announced retirement |
| Hector Garcia | P | 20.267 | Pittsburgh Pirates | West Virginia (A) | DL-7 Injured |
| Jesus Luzardo | p | 18.270 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (Florida HS) |
| Matt Rowland | p | 18.140 | Atlanta Braves | Gulf Coast Braves (Rk) | Signed out of draft (Georgia HS) |
| Zach Becherer | p | 20.297 | Atlanta Braves | Gulf Coast Braves (Rk) | Signed out of draft (Rend Lake) |
| Carlos Espinal | p | 19.249 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees East (Rk) |
| Brandon Bailey | p | 21.251 | Oakland Athletics | Arizona Athletics (Rk) | Signed out of draft (Gonzaga) |
| Jake Fraley | OF | 21.033 | Tampa Bay Rays | Hudson Valley (A-) | Signed out of draft (LSU) |
| Mark Ecker | p | 21.031 | Detroit Tigers | Connecticut (A-) | Signed out of draft (Texas A&M) |
| Roger Gonzalez | c | 22.237 | Oakland Athletics | Arizona Athletics (Rk) | Signed out of draft (Winthrop) |
| Sam Tewes | p | 21.141 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Signed out of draft (Wichita State) |
| TJ Zeuch | p | 20.331 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Signed out of draft (Pittsburgh) |
| Trent Giambrone | ss | 22.189 | Chicago Cubs | Eugene (A-) | Signed out of draft (Louisiana HS) |
| Andrew Bellatti | RP | 24.327 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| Bryson Myles | RF | 26.282 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
