| A.J. Reed | P | 23.046 | Houston Astros | Houston Astros (MLB) | Contract purchased from minors |
| Hector Sanchez | C | 26.220 | San Diego Padres | San Diego Padres (MLB) | Outrighted to minors |
| Tony Zych | P | 25.322 | Seattle Mariners | Seattle Mariners (MLB) | Transferred to 60-day DL |
| Adrian Sampson | P | 24.262 | Seattle Mariners | Seattle Mariners (MLB) | DL-15 Right flexor bundle strain |
| David Rollins | RP | 26.186 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Donn Roach | SP | 26.193 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from minors |
| Wade LeBlanc | RP | 31.322 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from minors |
| Nick Tropeano | SP | 25.302 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Hernan Perez | SS-RF | 25.091 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Reinstated from paternity leave |
| Adam Frazier | IF | 24.194 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Contract purchased from minors |
| Juan Nicasio | RP | 29.298 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Reinstated to active roster |
| Jorge Rondon | P | 28.130 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Designated for Assignment |
| Cole Figueroa | 3B | 28.361 | Pittsburgh Pirates | Indianapolis (AAA) | Designated for Assignment |
| Edubray Ramos | RP | 23.188 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Andrew Bailey | RP | 32.025 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-15 Strained left hamstring |
| Steven Delabar | RP | 32.344 | | | Released by Reds |
| Jordan Pacheco | 1B | 30.146 | Atlanta Braves | Atlanta Braves (MLB) | Signed to Minor League Contract |
| Junior Lake | LF | 26.090 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from minors |
| Will Venable | CF-RF | 33.239 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Designated for Assignment |
| Nick Tepesch | SP | 27.256 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Contract purchased from minors |
| Blake Wood | RP | 30.321 | Cincinnati Reds | Cincinnati Reds (MLB) | Reinstated from paternity leave |
| Alfredo Figaro | RP | 31.353 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed to Minor League Contract |
| Socrates Brito | CF | 23.292 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-15 Fractured right toe |
| Brandon Drury | 2B | 23.308 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Andrew Bellatti | RP | 24.325 | Tampa Bay Rays | Durham (AAA) | Designated for Assignment |
| Oswaldo Arcia | RF | 25.047 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Traded from Twins to Rays for future considerations |
| Bryce Brentz | LF | 27.177 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Chris Young | LF | 32.294 | Boston Red Sox | Boston Red Sox (MLB) | DL-15 Strained right hamstring |
| Danny Farquhar | RP | 29.128 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| T.J. McFarland | RP | 27.017 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Micker Adolfo | OF | 19.287 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Josh Almonte | OF | 22.148 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Marcos Almonte | 3b | 20.089 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Johel Atencio | c | 19.281 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Marlon Avea | C | 22.298 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
| Andres Ayon | of | 21.094 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Corey Baker | P | 26.214 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Keach Ballard | ss | 23.344 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Alex Balog | p | 23.344 | Colorado Rockies | Hartford (AA) | Assigned to Hartford (AA) |
| D.J. Baxendale | P | 25.199 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Brandon Bednar | IF-OF | 24.096 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Reiny Beltre | 3b | 19.344 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Aaron Blair | SP | 24.030 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Akeem Bostick | P | 21.052 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Matt Bower | p | 22.009 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Kelson Brown | 2B | 28.231 | Pittsburgh Pirates | Bristol (Rk) | Assigned to Bristol (Rk) |
| Alan Busenitz | P | 25.307 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Miguel Castro | P | 21.183 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Garrett Cleavinger | p | 22.063 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Christopher Comito | p | 20.000 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| Michael Conforto | LF | 23.116 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Garrett Cortright | P | 24.267 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Aaron Crow | RP | 29.226 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jacob Dahlstrand | P | 24.091 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Activated from disabled list |
| Jesen Therrien | P | 23.099 | Philadelphia Phillies | Clearwater (A+) | Activated from disabled list |
| Brett Eibner | CF | 27.205 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Jake Faria | P | 22.330 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Kyle Freeland | P | 23.042 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Willie Gabay | P | 24.358 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Robbie Garvey | CF-LF | 27.060 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Steve Geltz | RP | 28.237 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Alex Glenn | OF | 25.014 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Zack Godley | SP | 26.065 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Jack Goihl | c | 23.115 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Milton Gomez | P | 22.064 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Diego Goris | LF-2B | 25.199 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| John Gorman | p | 24.127 | Oakland Athletics | Arizona Athletics (Rk) | Assigned to Arizona Athletics (Rk) |
| Gabby Guerrero | P | 22.196 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Radley Haddad | C | 26.045 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Hunter Harvey | P | 21.198 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Activated from disabled list |
| Slade Heathcott | RF | 25.270 | Chicago White Sox | Arizona White Sox (Rk) | Assigned to Arizona White Sox (Rk) |
| Travis Hissong | P | 24.342 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Brent Honeywell | P | 21.086 | Tampa Bay Rays | Charlotte (A+) | Activated from disabled list |
| Edwin Jackson | RP | 32.290 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Tony Kemp | LF | 24.238 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Isiah Kiner-Falefa | SS | 21.094 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Nathan Kirby | p | 22.214 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Justin Lawrence | p | 21.212 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
| Carlos Leal | C | 24.348 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Edgar Lorenzo | of | 19.161 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Josh Lucas | P | 25.232 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Justin Maffei | OF | 24.303 | Pittsburgh Pirates | Bristol (Rk) | Assigned to Bristol (Rk) |
| Deven Marrero | 3B | 25.304 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Luis Marte | SS | 22.192 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Kenny Mathews | P | 22.323 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Bladimir Matos | p | 22.156 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Brian Matusz | RP | 29.134 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Kuehl Mceachern | P | 23.049 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Daniel Missaki | P | 20.077 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Adalberto Mondesi | OF | 20.334 | Kansas City Royals | Wilmington (A+) | Reinstated to active roster |
| Jose Monegro | P | 26.279 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Andrew Morales | P | 23.160 | St. Louis Cardinals | Springfield (AA) | Activated from disabled list |
| Gareth Morgan | OF | 20.074 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| James Naile | p | 23.137 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Chris O'Grady | P | 26.069 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Brian Olson | c | 23.155 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Luis Payano | OF | 20.044 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Richelson Pena | P | 22.269 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Ivan Pineyro | P | 24.270 | Miami Marlins | Jacksonville (AA) | Activated from disabled list |
| Moreno Polanco | p | 21.331 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Adam Ravenelle | P | 23.263 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Matt Reynolds | RP | 31.266 | San Francisco Giants | Richmond (AA) | Signed to Minor League Contract |
| C.J. Riefenhauser | RP | 26.146 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jamie Ritchie | C | 23.077 | Houston Astros | Lancaster (A+) | Activated from disabled list |
| Juan Robles | p | 18.231 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Kyle Ruchim | of | 23.318 | Chicago White Sox | Arizona White Sox (Rk) | Assigned to Arizona White Sox (Rk) |
| Lex Rutledge | P | 24.363 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Cristhopher Santamaria | P | 20.006 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Daniel Schlereth | P | 30.047 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Myles Schroder | C | 28.329 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| John Silviano | C | 21.349 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Kraig Sitton | P | 27.347 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Jake Skole | CF | 24.160 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| D.J. Stewart | of | 22.207 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Eric Surkamp | RP | 28.345 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Donavan Tate | CF | 25.271 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Ben Taylor | p | 23.225 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Chad Taylor | SS | 25.300 | New York Yankees | Gulf Coast Yankees (Rk) | Activated from disabled list |
| Nik Turley | P | 26.287 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Ricardo Valenzuela | C | 25.325 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Will Venable | CF-RF | 33.239 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| David Whitehead | P | 24.065 | Pittsburgh Pirates | Bristol (Rk) | Activated from disabled list |
| Taylor Williams | P | 24.340 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Grant Green | 2B | 28.272 | San Francisco Giants | Sacramento (AAA) | DL-7 Injured |
| Jeffrey Glenn | C | 24.277 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Adam Law | SS-2B | 26.140 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Joel Fisher | C-IF | 23.168 | Philadelphia Phillies | Reading (AA) | DL-7 Injured |
| Kyle Hooper | P | 25.028 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Sam Holland | P | 22.125 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| Sharif Othman | C | 27.094 | Miami Marlins | Jupiter (A+) | DL-7 Injured |
| Carl Anderson | OF-P | 23.297 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Kevin Garcia | C | 23.281 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Rinku Singh | P | 27.321 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Alexis Maldonado | SS | 25.013 | Toronto Blue Jays | Lansing (A) | DL-7 Injured |
| Michael Matuella | p | 22.022 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Sterling Wynn | P | 22.214 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Storm Rynard | P | 20.274 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Alan Marrero | c | 18.117 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (Puerto Rico HS) |
| Alexander Alvarez | c | 19.284 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to GCL Rays (Rk) |
| Alexander Rodriguez | of | 18.104 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Alfredo Bohorquez | if | 25.282 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to GCL Blue Jays (Rk) |
| Austin Sweet | p | 22.277 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (Missouri Baptist) |
| Bo Hellquist | p | 22.081 | Minnesota Twins | Gulf Coast Twins (Rk) | Signed as undrafted free agent (Minnesota-Duluth) |
| Bobby Eveld | p | 24.204 | Toronto Blue Jays | Bluefield (Rk) | Signed to Minor League Contract |
| Carlos Guzman | if | 18.040 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Claudio Scotti | p | 17.352 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to GCL Pirates (Rk) |
| Cody Dube | p | 21.247 | Baltimore Orioles | Aberdeen (A-) | Signed out of draft (Keene State) |
| Colton Thomson | p | 23.338 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Signed as undrafted free agent [New Mexico] |
| Cristhian Tortosa | p | 17.238 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Cristian Pache | of | 17.218 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to GCL Braves (Rk) |
| Dane Hutcheon | ss | 21.346 | Minnesota Twins | Gulf Coast Twins (Rk) | Signed out of draft (Montevallo) |
| Derian Cruz | ss | 17.265 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to GCL Braves (Rk) |
| Eduard Rosillo | p | 22.185 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to GCL Rays (Rk) |
| Edward Cabrera | p | 18.073 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to GCL Marlins (Rk) |
| Elys Escobar | c | 19.277 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Enger Jimenez | of | 20.357 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Eric Diomartich | p | 22.052 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Signed as undra |
| Eric Diomartich | p | 22.052 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (Biola) |
| Evan Rogers | if | 22.057 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Signed as undrafted free agent (Mars Hill) |
| Franklin Arias | of | 19.167 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Signed as undrafted free agent (GCL Tigers East) |
| Gui Yuan Xu | 1b | 20.148 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) |
| Hector Rodriguez | p | 19.203 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Ian Hardman | p | 20.283 | Houston Astros | Gulf Coast Astros (Rk) | Signed out of draft (Seminole State OK) |
| Javier Monzon | ss | 23.139 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to GCL Blue Jays (Rk) |
| Javier Villarroel | p | 18.237 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Jesus Rodriguez | p | 18.129 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Joey Rose | 3b | 18.156 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Signed out of draft (New Jersey HS) |
| Johandry Cortez | c | 18.032 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Jose Gonzalez | of | 17.346 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Jose Salas | ss | 19.069 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Juan Soto | of | 17.243 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to GCL Nationals (Rk) |
| Kale Fultz | p | 22.086 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Signed as undrafted free agent (Central Baptist) |
| Kevin Williams | p | 25.074 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (LSU Shreveport) |
| Keyder Aristigueta | 2b | 20.144 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Kilber Santana | p | 17.253 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Lenin Rodriguez | c | 18.091 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Luis Carrasco | p | 21.287 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Luis Gonzalez | p | 21.354 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Malvin Matos | of | 19.310 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Mauricio Llovera | p | 20.069 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Maximo Castillo | p | 17.052 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to GCL Blue Jays (Rk) |
| Miguel Sanchez | p | 22.176 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to AZL Brewers (Rk) |
| Moises Bello | 3b | 19.012 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Moises Gomez | of | 17.302 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to GCL Rays (Rk) |
| Nick Jobst | p | 22.066 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (USC Aiken) |
| Oskerlly Sanchez | p | 20.302 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Raul Rivas | 2b | 19.241 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Rene Pinto | c | 19.235 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to GCL Rays (Rk) |
| Ricardo Cubillan | ss | 18.144 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to GCL Red Sox (Rk) |
| Ronaldo Lopez | p | 18.169 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Tim Holmes | p | 22.252 | New York Yankees | Gulf Coast Yankees (Rk) | Signed as undrafted free agent (San Jacinto) |
| Troy Sieber | 1b | 21.003 | Houston Astros | Gulf Coast Astros (Rk) | Signed out of draft (Saint Leo) |
| Victor Ngoepe | ss | 18.136 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to GCL Pirates (Rk) |
| Wladimir Pinto | p | 18.133 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Jason Erickson | p | 29.142 | Pittsburgh Pirates | Bristol (Rk) | Assigned to Bristol (Rk) |
| Andy Pineda | of | 19.226 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Brandon Benavente | c | 18.295 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Bryan Abreu | p | 19.064 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Carlos Luna | p | 19.273 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to AZL Brewers (Rk) |
| Cesar Rosado | p | 20.003 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Christopher Luciano | 1b | 20.025 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Cristian Javier | p | 19.091 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Damaso Marte | ss | 17.315 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Assigned to AZL Dodgers (Rk) |
| Eleardo Cabrera | of | 20.230 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Erik Garcia | c | 23.094 | St. Louis Cardinals | Johnson City (Rk) | Signed as undrafted free agent (Missouri Baptist) |
| Franchi Batista | p | 20.030 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers East (Rk) |
| Gabriel Valdez | p | 20.244 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Hansel Paulino | p | 20.174 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Jason Lopez | c | 18.101 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees East (Rk) |
| Jorge Alcala | p | 20.333 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Jose Ramos | p | 19.325 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Juan Pineda | 2b | 18.145 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Leovanny Rodriguez | p | 20.012 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Luis Hernandez | 3b | 18.043 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) |
| Luis Vasquez | p | 22.216 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Oliver Toribio | c | 20.018 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Oscar Campos | c | 19.199 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Pablo Ochoa | p | 18.165 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to AZL Cubs (Rk) |
| Randy Vasquez | c | 20.104 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Wilson Amador | of | 19.193 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Anthony Ciavarella | p | 22.316 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Signed out of draft (Monmouth) |
| Brody Westmoreland | 3b | 20.308 | Houston Astros | Gulf Coast Astros (Rk) | Signed out of draft (Colorado HS) |
| Chase Hodson | p | 23.350 | New York Yankees | Gulf Coast Yankees (Rk) | Signed as undrafted free agent (Texas State) |
| Dylan Delso | c | 23.288 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (Oklahoma City) |
| Griffin Jax | p | 21.215 | Minnesota Twins | Elizabethton (Rk) | Signed out of draft (Air Force) |
| Joe Napolitano | p | 24.136 | New York Mets | Gulf Coast Mets (Rk) | Signed as undrafted free agent (St. John's) |
| Joey Graziano | p | 22.221 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (St. John's) |
| Matthew Gorst | p | 21.305 | Boston Red Sox | Lowell (A-) | Signed out of draft (Georgia Tech) |
| Reed Gamache | 2b | 22.173 | New York Mets | Gulf Coast Mets (Rk) | Signed as undrafted free agent (SUNY Binghamton) |
| Robert Calvano | p | 23.118 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Signed out of draft (Nebraska-Omaha) |
| Luis Torrealba | of | 19.275 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Matt Murray | P | 26.179 | | | Released by Royals |
