| Dominic Leone | RP | 24.183 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Phil Coke | RP | 33.281 | New York Yankees | New York Yankees (MLB) | Signed to Minor League Contract |
| Keith Hessler | RP | 27.042 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Mobile (AA) |
| Kevin Gausman | SP | 25.110 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| David Murphy | LF | 34.190 | | | Released by Twins |
| Louis Coleman | RP | 30.022 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Reinstated from bereavement list |
| Joaquin Benoit | RP | 38.274 | Seattle Mariners | Seattle Mariners (MLB) | DL-15 Right shoulder inflammation |
| Mayckol Guaipe | RP | 25.258 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Scott Oberg | RP | 26.044 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from Albuquerque (AAA) |
| Nick Hundley | C | 32.231 | Colorado Rockies | Colorado Rockies (MLB) | Activated from DL |
| Keone Kela | RP | 23.010 | Texas Rangers | Texas Rangers (MLB) | Transferred to 60-day DL |
| Cesar Ramos | RP | 31.308 | Texas Rangers | Texas Rangers (MLB) | Contract purchased from minors |
| Carlos Carrasco | SP | 29.036 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Strained left hamstring |
| Alex Meyer | RP | 26.113 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Danny Santana | CF | 25.170 | Minnesota Twins | Minnesota Twins (MLB) | Activated from DL |
| Andrew Triggs | P | 27.041 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Jose Valdez | P | 26.056 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Jeff Ferrell | RP | 25.154 | Detroit Tigers | Toledo (AAA) | Activated from DL and assigned to Toledo (AAA) |
| Layne Somsen | P | 26.325 | Cincinnati Reds | Cincinnati Reds (MLB) | Contract purchased from minors |
| Jay Bruce | RF | 29.023 | Cincinnati Reds | Cincinnati Reds (MLB) | Placed on paternity leave |
| Miguel Gonzalez | SP | 31.334 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Michael Feliz | RP | 22.302 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Rogelio Armenteros | p | 21.300 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Blake Bass | p | 22.327 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Steve Bean | C | 22.223 | St. Louis Cardinals | Palm Beach (A+) | Activated from disabled list |
| Aaron Blanton | SS | 22.237 | Miami Marlins | Greensboro (A) | Activated from disabled list |
| Brandon Brosher | OF | 21.068 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Byron Buxton | CF | 22.129 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Derek Campbell | IF | 24.303 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Jarred Cosart | SP | 25.336 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Michael Crotta | P | 31.214 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Cody Dent | SS | 24.269 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Alex Farina | p | 22.331 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| Ryan Flaherty | 2B | 29.273 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Dante Flores | 2b | 23.018 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Jared Foster | 2b | 23.175 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Jeff Gardner | C | 24.096 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Daniel Gonzalez | c | 20.142 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Ben Griset | P | 24.045 | New York Mets | St. Lucie (A+) | Reinstated to active roster |
| Trevor Hildenberger | P | 25.132 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Jesse Hodges | 3b | 22.028 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Drew Hutchison | RP | 25.247 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Jesse Jenner | c | 22.282 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Ulises Joaquin | P | 23.319 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Christian Jones | P | 25.089 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Max Kepler | RF | 23.075 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Brody Koerner | p | 22.191 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Casey Lawrence | P | 28.181 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Trey Mancini | 1B | 24.039 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Danny Mendick | ss | 22.210 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Jose Mesa | P | 22.256 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Kyle Miller | p | 22.145 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Luis Morales | P | 23.041 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Omar Narvaez | C-1B | 24.076 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Miguel Nunez | P | 23.181 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Chris O'Dowd | C | 25.204 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Brandon Peterson | P | 24.216 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Gustavo Pierre | SS | 24.120 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Jose Pirela | 2B | 26.156 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| James Pugliese | P | 23.257 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) for rehab |
| Yefry Ramirez | P | 22.149 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Cody Reed | P | 23.011 | Cincinnati Reds | Louisville (AAA) | Activated from disabled list |
| James Reeves | p | 22.323 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Gerardo Reyes | P | 22.348 | San Diego Padres | Fort Wayne (A) | Activated from disabled list |
| Luis Reynoso | SS | 21.236 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| John Richy | P | 23.272 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Bryan Rodriguez | P | 24.295 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Cleuluis Rondon | P | 22.013 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Juan Santos | P | 20.240 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Wynston Sawyer | C | 24.164 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Nick Schulz | OF | 24.359 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Louis Silverio | OF | 22.132 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Mason Smith | CF | 21.041 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Jency Solis | P | 23.063 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Luis Tejada | 1B | 23.196 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Ka'ai Tom | of | 21.337 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Damek Tomscha | 3B | 24.243 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Jose Valdez | P | 26.056 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Mick VanVossen | p | 23.178 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Luke Westphal | P | 26.316 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Alex Wimmers | P | 27.176 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Eric Yardley | P | 25.251 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Brandon Gomes | RP | 31.285 | Chicago Cubs | Iowa (AAA) | Placed on temporary inactive list |
| Chad Smith | P | 26.206 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Rob Wooten | RP | 30.279 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Kris Hall | P | 24.323 | Oakland Athletics | Midland (AA) | DL-7 Injured |
| Michael Wagner | P | 24.206 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Mike McCarthy | P | 28.160 | Boston Red Sox | Portland (AA) | DL-7 Injured |
| Mitch Delfino | IF | 25.103 | San Francisco Giants | Sacramento (AAA) | DL-7 Injured |
| Seth Lugo | P | 26.160 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Stephen Landazuri | P | 24.111 | Seattle Mariners | Seattle Mariners (MLB) | Assigned to extended spring training |
| Victor Mateo | P | 26.273 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Brett Lee | P | 25.218 | | | Released by Twins |
| Derek Miller | IF | 23.282 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Jeff McNeil | IF-OF | 24.018 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Jeff McNeil | IF-OF | 24.018 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Nate Hyatt | IF-P | 25.212 | Los Angeles Angels | Arkansas (AA) | DL-7 Injured |
| Pin-Chieh Chen | CF | 24.278 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Ryan Newell | P | 24.313 | Miami Marlins | Jacksonville (AA) | DL-7 Injured |
| Stefan Sabol | C | 24.084 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Jose Berrios | P | 21.334 | Minnesota Twins | Minnesota Twins (MLB) | Contract purchased from minors |
| Blake Logan | P | 24.105 | | | Announced retirement |
