| Jose De Paula | RP | 28.036 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed to Minor League Contract |
| Munenori Kawasaki | 3B | 34.310 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| Kyle Schwarber | C-LF | 23.035 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Torn ligaments in left knee |
| Matt Buschmann | RP | 32.056 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Contract purchased from minors |
| Kyle Drabek | P | 28.123 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Designated for Assignment |
| Justin Ruggiano | cf | 33.362 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| A.J. Griffin | SP | 28.072 | Texas Rangers | Texas Rangers (MLB) | Contract purchased from minors |
| Emilio Bonifacio | DH | 30.351 | | | Refused minor league assignment, declared free agent |
| Robbie Erlin | SP | 25.183 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Matt Thornton | RP | 39.206 | San Diego Padres | San Diego Padres (MLB) | DL-15 Left achilles tendinitis |
| Ariel Pena | P | 26.324 | Milwaukee Brewers | Colorado Springs (AAA) | Outrighted to minors |
| Connor Lien | OF | 22.025 | Atlanta Braves | Mississippi (AA) | DL-7 left hand |
| Zack Tillery | IF-P | 23.087 | Minnesota Twins | Cedar Rapids (A) | DL-7 Right triceps tendinitis |
| Phil Maton | p | 23.015 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Franco Terrero | p | 20.325 | Kansas City Royals | Lexington (A) | Assigned Lexington (A) |
| Tyler Krieger | ss | 22.083 | Cleveland Indians | Mahoning Valley (A-) | Signed out of draft (Clemson) |
| A.J. Achter | RP | 27.225 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from minors |
| Cam Bedrosian | RP | 24.190 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Nate Hyatt | IF-P | 25.195 | Los Angeles Angels | Los Angeles Angels (MLB) | Assignment unknown |
| Burke Badenhop | RP | 33.060 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Wesley Benjamin | p | 22.257 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Kyle Blanks | LF | 29.210 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Brennan Boesch | LF | 30.362 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Royce Bolinger | OF | 25.240 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Bryce Brentz | RF | 27.100 | Boston Red Sox | Pawtucket (AAA) | Activated from disabled list |
| Mike Connolly | IF | 24.161 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Jordan Cowan | SS | 20.362 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Ryan Etsell | P | 24.113 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| Grayson Garvin | P | 26.164 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Deolis Guerra | RP | 26.357 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Danny Hultzen | P | 26.132 | Seattle Mariners | Jackson (AA) | Activated from disabled list |
| Jerry Keel | p | 22.195 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Bradley Keller | of | 19.115 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Steve Kent | p | 26.336 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Mike Kickham | RP | 27.118 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Tyler Knigge | P | 27.164 | Seattle Mariners | Jackson (AA) | Activated from disabled list |
| Bobby Korecky | P | 36.206 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| George Kottaras | c | 32.329 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Tyler Krieger | ss | 22.083 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Carlos Maldonado | C | 37.096 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Derek Miller | IF | 23.265 | Boston Red Sox | Portland (AA) | Activated from disabled list |
| Zach Nuding | P | 26.011 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Justin O'Conner | C | 24.009 | Tampa Bay Rays | Montgomery (AA) | Activated from disabled list |
| Dan Paolini | 2B | 26.180 | Seattle Mariners | Jackson (AA) | Activated from disabled list |
| Matt Pare | 1B | 25.143 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Jimy Perez | 3b | 22.056 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Ricardo Rodriguez | P | 23.221 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Jose Rosario | P | 25.223 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Michael Smith | P | 26.068 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| Jordan Tarsovich | 2b | 24.294 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Lance Thonvold | p | 22.275 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Damek Tomscha | 3B | 24.226 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Ryan Uhl | 1b | 22.318 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Sutton Whiting | 2b | 23.331 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Burch Smith | RP | 25.362 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| Justin Marks | P | 28.088 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| Neil Wagner | RP | 32.099 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| Ryan Brett | 2B | 24.183 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| Vinny Rottino | RF-LF | 36.002 | Chicago White Sox | Charlotte (AAA) | DL-7 Injured |
| Angel Sanchez | P | 26.132 | Pittsburgh Pirates | Altoona (AA) | DL-7 Injured |
| Cameron Seitzer | 1B | 26.088 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Assigned to extended spring training |
| Miguel Chalas | P | 23.286 | Chicago White Sox | Charlotte (AAA) | DL-7 Injured |
| Neil Holland | P | 27.238 | Washington Nationals | Harrisburg (AA) | DL-7 Injured |
| Paul Smyth | P | 29.008 | Arizona Diamondbacks | Reno (AAA) | DL-7 Injured |
| Tim Alderson | P | 27.157 | Washington Nationals | Harrisburg (AA) | DL-7 Injured |
| Brian Rauh | P | 24.261 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Drew Vettleson | RF | 24.265 | Washington Nationals | Harrisburg (AA) | DL-7 Injured |
| Robert Benincasa | P | 25.216 | Washington Nationals | Harrisburg (AA) | DL-7 Injured |
| Stephen Bruno | SS | 25.143 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Steve Perakslis | P | 25.084 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Andruth Ramirez | C | 27.030 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Brenden Webb | RF | 26.044 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Hector Silvestre | P | 23.116 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Kylin Turnbull | P | 26.209 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Johan Diaz | p | 23.159 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Chris Reed | P | 25.324 | Miami Marlins | Miami Marlins (MLB) | Assignment Unknown |
| Adam Weisenburger | C | 27.117 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Assignment Unknown |
| Arturo Rodriguez | C | 24.189 | Miami Marlins | Miami Marlins (MLB) | Assignment Unknown |
| Ben Klimesh | P | 25.330 | Cincinnati Reds | Cincinnati Reds (MLB) | Assignment Unknown |
| Blake Logan | P | 24.088 | Miami Marlins | Miami Marlins (MLB) | Assignment Unknown |
| Bryan Case | c | 23.240 | San Francisco Giants | San Francisco Giants (MLB) | Assignment Unknown |
| Bryce Morrow | P | 28.098 | San Diego Padres | San Diego Padres (MLB) | Assignment Unknown |
| Casey McElroy | 2B | 26.102 | San Diego Padres | San Diego Padres (MLB) | Assignment Unknown |
| Cesar Galvez | 2B | 24.260 | Colorado Rockies | Colorado Rockies (MLB) | Assignment Unknown |
| Chad Rogers | P | 26.249 | Cincinnati Reds | Cincinnati Reds (MLB) | Assignment Unknown |
| Chan Moon | SS | 25.017 | Houston Astros | Houston Astros (MLB) | Assignment Unknown |
| Dennis O'Grady | P | 26.327 | San Diego Padres | San Diego Padres (MLB) | Assignment Unknown |
| Devin Burke | P | 25.048 | Colorado Rockies | Colorado Rockies (MLB) | Assignment Unknown |
| Eric Ruth | P | 25.195 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Erik Gonzalez | 3B | 24.222 | Cleveland Indians | Cleveland Indians (MLB) | Assignment Unknown |
| Frank Batista | P | 26.348 | Chicago Cubs | Chicago Cubs (MLB) | Assignment Unknown |
| Jayce Boyd | IF | 25.100 | New York Mets | New York Mets (MLB) | Assignment Unknown |
| Josciel Veras | SS | 23.123 | Cincinnati Reds | Cincinnati Reds (MLB) | Assignment Unknown |
| Matthew Spann | P | 25.051 | Washington Nationals | Washington Nationals (MLB) | Assignment Unknown |
| Mike McCarthy | P | 28.143 | Boston Red Sox | Boston Red Sox (MLB) | Assignment Unknown |
| Mike McCarthy | P | 28.143 | Boston Red Sox | Boston Red Sox (MLB) | Assignment Unknown |
| Rafael Pineda | p | 25.065 | Seattle Mariners | Bakersfield (A+) | DL-60 Injured |
| Sean Buckley | 3B | 26.218 | Cincinnati Reds | Cincinnati Reds (MLB) | Assignment Unknown |
| Tanner Peters | P | 25.246 | Oakland Athletics | Nashville (AAA) | DL-7 Injured |
| Will Kengor | SS | 23.259 | Detroit Tigers | Detroit Tigers (MLB) | Assignment Unknown |
| Zach Osborne | IF | 25.354 | Colorado Rockies | Colorado Rockies (MLB) | Assignment Unknown |
| Andy Fermin | 3B | 26.256 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Assignment Unknown |
| Colin Bates | P | 28.030 | Washington Nationals | Washington Nationals (MLB) | Assignment Unknown |
| D.J. Brown | P | 25.132 | Cleveland Indians | Cleveland Indians (MLB) | Assignment Unknown |
| Jordan Harrison | P | 25.000 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Assignment Unknown |
| Noel Cuevas | LF-CF | 24.190 | Colorado Rockies | Colorado Rockies (MLB) | Assignment Unknown |
| Tyler Ybarra | P | 26.119 | Colorado Rockies | Colorado Rockies (MLB) | Assignment Unknown |
| Daris Vargas | p | 23.240 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Darren Seferina | 2B | 22.075 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Assignment Unknown |
| David Armendariz | OF | 24.231 | Cleveland Indians | Cleveland Indians (MLB) | Assignment Unknown |
| David Sopilka | C | 22.222 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Derrick Sylvester | P | 24.356 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Devin Williams | P | 21.200 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Assignment Unknown |
| Dewin Perez | P | 21.192 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Assignment Unknown |
| Donny Sands | 3b | 19.328 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Drew Smith | p | 22.197 | Detroit Tigers | West Michigan (A) | DL-7 Injured |
| Dusten Knight | P | 25.214 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Elvis Rubio | OF | 21.281 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Eudor Garcia | IF | 21.327 | New York Mets | New York Mets (MLB) | Placed on restricted list |
| Francisco Contreras | 3B | 23.127 | Detroit Tigers | Detroit Tigers (MLB) | Assignment Unknown |
| Francisco Jimenez | P | 21.187 | Baltimore Orioles | Baltimore Orioles (MLB) | Assignment Unknown |
| Garrett Mattlage | SS | 23.043 | Detroit Tigers | Detroit Tigers (MLB) | Assignment Unknown |
| Garrett Mundell | p | 23.052 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Greg McCall | C | 24.106 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Assignment Unknown |
| J.J. Franco | SS | 24.067 | Atlanta Braves | Atlanta Braves (MLB) | Assigned to extended spring training |
| Jacob Morris | OF | 25.111 | Chicago White Sox | Chicago White Sox (MLB) | Assignment Unknown |
| Jake Mayers | P | 25.244 | Washington Nationals | Washington Nationals (MLB) | Assigned to extended spring training |
| Janser Severino | P | 24.206 | Baltimore Orioles | Delmarva (A) | DL-7 Injured |
| Jason Hoppe | P | 23.300 | Los Angeles Angels | Los Angeles Angels (MLB) | Assignment Unknown |
| Jeff Gardner | C | 24.079 | Washington Nationals | Washington Nationals (MLB) | Assignment Unknown |
| Jeff Kinley | p | 24.054 | Miami Marlins | Miami Marlins (MLB) | Assignment Unknown |
| Jeffeson Medina | p | 21.313 | Seattle Mariners | Seattle Mariners (MLB) | Assignment Unknown |
| Jerry Downs | of | 22.108 | Boston Red Sox | Boston Red Sox (MLB) | Assignment Unknown |
| Jesse Hodges | 3b | 22.011 | Chicago Cubs | Chicago Cubs (MLB) | Assignment Unknown |
| Jimmy Allen | 2B | 24.096 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Assignment Unknown |
| Joe Harvey | P | 24.091 | New York Yankees | Charleston (sc) (A) | DL-7 Injured |
| Jonathan Van Eaton | P | 24.329 | Los Angeles Angels | Los Angeles Angels (MLB) | Assignment Unknown |
| Jose Castillo | P | 20.090 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Jose Mesa | P | 22.239 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Jose Regalado | P | 24.142 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Assignment Unknown |
| Josh Swirchak | 2b | 23.007 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Assignment Unknown |
| Juan Robles | p | 18.154 | Houston Astros | Houston Astros (MLB) | Assignment Unknown |
| Justin Ferrell | P | 21.353 | Houston Astros | Houston Astros (MLB) | Assignment Unknown |
| Justin Kamplain | P | 23.055 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Kelvin Vasquez | P | 23.003 | Texas Rangers | Texas Rangers (MLB) | Assigned to extended spring training |
| Kristian Brito | 1B | 21.110 | Seattle Mariners | Seattle Mariners (MLB) | Assignment Unknown |
| Luis Reynoso | SS | 21.219 | Houston Astros | Houston Astros (MLB) | Assignment Unknown |
| Luis Torrens | C | 19.342 | New York Yankees | Charleston (sc) (A) | DL-7 Injured |
| Luke Eubank | P | 22.044 | Cleveland Indians | Cleveland Indians (MLB) | Assignment Unknown |
| Marlon Avea | C | 22.221 | Houston Astros | Tri City (A-) | Assigned to Tri-City (A-) |
| Marty Herum | 3B | 24.115 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assignment Unknown |
| Matt Campbell | P | 24.194 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Assignment Unknown |
| Max Kuhn | SS | 23.211 | Oakland Athletics | Oakland Athletics (MLB) | Assigned to extended spring training |
| Michael Bolaski | 3B | 24.064 | Los Angeles Angels | Los Angeles Angels (MLB) | Assignment Unknown |
| Michael Burke | P | 23.225 | Baltimore Orioles | Baltimore Orioles (MLB) | Assignment Unknown |
| Mike Fagan | P | 23.332 | Oakland Athletics | Oakland Athletics (MLB) | Assignment Unknown |
| Mitch Watrous | P | 23.099 | San Diego Padres | San Diego Padres (MLB) | Assignment Unknown |
| Natanael Mejia | C | 23.273 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Nathan Kirby | p | 22.137 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Assignment Unknown |
| Nick Flair | ss | 23.160 | Los Angeles Angels | Los Angeles Angels (MLB) | Assignment Unknown |
| Nick Frey | P | 24.223 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Assignment Unknown |
| Nick Gardewine | P | 22.237 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Nick Monroe | p | 22.034 | San Diego Padres | San Diego Padres (MLB) | Assignment Unknown |
| Omar Cotto | of | 24.041 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Assignment Unknown |
| Ordomar Valdez | 2B | 21.347 | Cleveland Indians | Cleveland Indians (MLB) | Assignment Unknown |
| Oriel Caicedo | P | 22.085 | Atlanta Braves | Atlanta Braves (MLB) | Assignment Unknown |
| Quinnton Mack | of | 24.058 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assignment Unknown |
| Robbie Perkins | C | 21.315 | Colorado Rockies | Colorado Rockies (MLB) | Placed on Reseve List |
| Ryan Burr | p | 21.316 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assignment Unknown |
| Ryan Stephens | OF | 23.277 | Colorado Rockies | Colorado Rockies (MLB) | Assignment Unknown |
| Sean Carley | P | 25.102 | New York Yankees | New York Yankees (MLB) | Assignment Unknown |
| Sean Smedley | C-1B | 25.193 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Assignment Unknown |
| Seth Conner | 3B | 24.071 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Assignment Unknown |
| Spencer Turnbull | P | 23.203 | Detroit Tigers | West Michigan (A) | DL-7 Injured |
| Stephen Tarpley | P | 23.051 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Assignment Unknown |
| Steven Mateo | 1B | 23.233 | Los Angeles Angels | Los Angeles Angels (MLB) | Assignment Unknown |
| Taylor Cockrell | p | 21.292 | Atlanta Braves | Atlanta Braves (MLB) | Assignment Unknown |
| Thyago Vieira | P | 23.092 | Seattle Mariners | Seattle Mariners (MLB) | Assignment Unknown |
| Tim Proudfoot | ss | 23.017 | Oakland Athletics | Oakland Athletics (MLB) | Assignment Unknown |
| Trey Teakell | p | 24.052 | Detroit Tigers | West Michigan (A) | DL-7 Injured |
| Ty Hensley | P | 22.253 | New York Yankees | Charleston (sc) (A) | DL-7 Injured |
| Ty Sterner | P | 23.121 | Cincinnati Reds | Cincinnati Reds (MLB) | Assigned to extended spring training |
| Victor Padron | OF | 21.278 | Detroit Tigers | Detroit Tigers (MLB) | Assignment Unknown |
| Vimael Machin | ss | 22.196 | Chicago Cubs | Chicago Cubs (MLB) | Assignment Unknown |
| Wander Franco | 3b | 19.180 | Houston Astros | Houston Astros (MLB) | Assignment Unknown |
| Will Remillard | C | 23.203 | Chicago Cubs | Chicago Cubs (MLB) | Assignment Unknown |
| Xavier Turner | 3b | 22.228 | Texas Rangers | Texas Rangers (MLB) | Assigned to extended spring training |
| Yermin Mercedes | C | 23.054 | Baltimore Orioles | Baltimore Orioles (MLB) | Assignment Unknown |
| Carl Anderson | OF-P | 23.220 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Assignment Unknown |
| Iolana Akau | C | 20.222 | Oakland Athletics | Stockton (A+) | DL-7 Injured |
| Brandon Belt | 1B | 27.354 | San Francisco Giants | San Francisco Giants (MLB) | Signed to 5-year contract for 2017-2021 ($72.8m) [Extension] 8.8--16--16--16--16 |
| Tyrone Taylor | OF | 22.077 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
