| Ronald Belisario | RP | 32.186 | | | Refused minor league assignment, declared free agent |
| Jonathan Schoop | 2B | 23.273 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Mike Morse | LF | 33.105 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Jake Marisnick | CF | 24.097 | Houston Astros | Houston Astros (MLB) | Activated from DL |
| Doug Bernier | ss | 35.011 | Minnesota Twins | Rochester (AAA) | Outrighted to minors |
| Jarred Cosart | SP | 25.041 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Oscar Hernandez | C | 21.361 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Tuffy Gosewisch | c | 31.323 | Arizona Diamondbacks | Reno (AAA) | Transferred to 60-day DL |
| Danny Dorn | PH | 30.350 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Patrick Corbin | SP | 25.351 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Justin Miller | RP | 28.022 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| John Axford | RP | 32.095 | Colorado Rockies | Colorado Rockies (MLB) | Reinstated from restricted list |
| Ryan Flaherty | 2B | 28.343 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Domingo Santana | RF | 22.334 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Anthony Ranaudo | RP | 25.299 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Taylor Teagarden | C | 31.197 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| David Ross | C | 38.108 | Chicago Cubs | Chicago Cubs (MLB) | DL-7 Concussion |
| Tommy La Stella | 2B | 26.155 | Chicago Cubs | Chicago Cubs (MLB) | Transferred to 60-day DL |
| Gonzalez Germen | RP | 27.286 | Chicago Cubs | Iowa (AAA) | Designated for Assignment |
| Everett Teaford | RP | 31.051 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Contract purchased from minors |
| Marc Krauss | 1B | 27.274 | Tampa Bay Rays | Durham (AAA) | Designated for Assignment |
| Mitch Harris | RP | 29.240 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| James Jones | CF | 26.284 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Mayckol Guaipe | RP | 24.328 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Steven Wright | RP | 30.309 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Noe Ramirez | RP | 25.195 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Miguel Cabrera | 1B | 32.078 | Detroit Tigers | Detroit Tigers (MLB) | DL-15 Left calf strain |
| Jefry Marte | 1B | 24.014 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Matt Harrison | SP | 29.323 | Texas Rangers | Texas Rangers (MLB) | Activated from DL |
| Neftali Feliz | RP | 27.064 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| Hanser Alberto | 2B | 22.261 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Michael Antonini | P | 29.333 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Brandon Barker | P | 22.319 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Cael Brockmeyer | C-1B | 23.271 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Oliver Caraballo | C | 20.314 | Texas Rangers | High Desert (A+) | Activated from disabled list |
| Miguel Castro | P | 20.193 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Andrew Church | P | 20.271 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Austin Cousino | OF | 22.079 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Varonex Cuevas | SS | 22.346 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| John Ely | P | 29.049 | Milwaukee Brewers | Arizona Brewers (Rk) | Activated from disabled list |
| Dustin Emmons | P | 23.250 | Atlanta Braves | Carolina (A+) | Assigned to Carolina (A+) |
| Anthony Fernandez | P | 25.027 | Seattle Mariners | Jackson (AA) | Assigned to Jackson (AA) |
| Jordan Foley | P | 21.358 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Garrett Fulenchek | P | 19.028 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Luis Gamez | P | 19.010 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| John Gant | P | 22.333 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Leury Garcia | SS | 24.109 | Chicago White Sox | Charlotte (AAA) | Activated from disabled list |
| Michael Gibbons | p | 22.072 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Tommy Hanson | SP | 28.311 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Cody Harris | P | 23.092 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Taylor Hearn | p | 20.309 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Michael Heesch | P | 25.051 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Ralph Henriquez | C | 28.089 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Josh Hodges | P | 24.014 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Kyle Keller | p | 22.068 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Brandon Leibrandt | P | 22.204 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Brad Markey | P | 23.124 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Lino Martinez | P | 23.292 | Philadelphia Phillies | Clearwater (A+) | Activated from disabled list |
| Jordan Mills | P | 23.055 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Michael O'Brien | P | 25.124 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Connor Overton | P | 21.346 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Tim Peterson | P | 24.133 | New York Mets | Savannah (A) | Reinstated to active roster |
| Joel Pineiro | P | 36.283 | Toronto Blue Jays | Buffalo (AAA) | Reinstated to active roster |
| Santiago Rodriguez | p | 21.021 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Wilman Rodriguez | OF | 24.028 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| John Ruettiger | CF | 25.287 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Pedro Ruiz | 2B-SS | 23.310 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| Rob Segedin | 3B | 26.237 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Brandon Show | P | 22.247 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Grant Sides | P | 26.013 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Stephen Smith | P | 29.051 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Eric Stults | SP | 35.209 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Matt Szczur | LF | 25.350 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Ramon Troncoso | RP | 32.139 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Ricardo Valencia | c | 22.173 | Texas Rangers | High Desert (A+) | Activated from disabled list |
| Andrew Velazquez | SS | 20.356 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Victor Veliz | P | 21.272 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| K.J. Woods | RF | 19.362 | Miami Marlins | Greensboro (A) | Reinstated to active roster |
| Jorge Zavala | P | 21.025 | Atlanta Braves | Carolina (A+) | Activated from disabled list |
| Brian Bogusevic | lf | 31.138 | Philadelphia Phillies | Lehigh Valley (AAA) | Placed on temporary inactive list |
| Casey Coleman | P | 28.002 | Kansas City Royals | Omaha (AAA) | Placed on temporary inactive list |
| Casey Kotchman | 1b | 32.133 | Kansas City Royals | Omaha (AAA) | Placed on temporary inactive list |
| Eric Fryer | C | 29.313 | Minnesota Twins | Rochester (AAA) | Placed on temporary inactive list |
| Jordan Norberto | P | 28.209 | Tampa Bay Rays | Durham (AAA) | Placed on temporary inactive list |
| Lucas Luetge | RP | 28.131 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
| Aaron Blair | P | 23.040 | Arizona Diamondbacks | Reno (AAA) | Placed on temporary inactive list |
| Buddy Baumann | P | 27.209 | Kansas City Royals | Omaha (AAA) | Placed on temporary inactive list |
| Jacob Wilson | IF | 24.341 | St. Louis Cardinals | Memphis (AAA) | Placed on temporary inactive list |
| Jake Barrett | P | 23.349 | Arizona Diamondbacks | Mobile (AA) | Placed on temporary inactive list |
| Jordan Lennerton | 1B | 29.139 | Detroit Tigers | Toledo (AAA) | Placed on temporary inactive list |
| Matt Fields | 1B | 29.362 | | | Released by Royals |
| Nate Hanson | 1B | 28.147 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Patrick Kivlehan | 3B | 25.195 | Seattle Mariners | Tacoma (AAA) | Placed on temporary inactive list |
| Pedro Rodriguez | P | 27.248 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Scott McGregor | P | 28.198 | Washington Nationals | Syracuse (AAA) | Placed on temporary inactive list |
| Trevor Miller | P | 24.022 | | | Released by Mariners |
| Tyler Deloach | P | 24.084 | Los Angeles Angels | Salt Lake (AAA) | Placed on temporary inactive list |
| Brian Ellington | P | 24.335 | Miami Marlins | Jacksonville (AA) | Placed on temporary inactive list |
| Chris O'Brien | C | 25.346 | Baltimore Orioles | Bowie (AA) | DL-7 Injured |
| Joe Musgrove | P | 22.213 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Jordan Shipers | P | 24.008 | | | Announced retirement |
| Paul Sewald | P | 25.040 | New York Mets | Binghamton (AA) | Placed on temporary inactive list |
| Sean Jamieson | SS | 26.125 | Arizona Diamondbacks | Mobile (AA) | Placed on temporary inactive list |
| Tony Wolters | SS | 23.026 | Cleveland Indians | Akron (AA) | DL-7 Injured |
| Tyler Mizenko | P | 25.087 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Yoan Lopez | P | 22.184 | Arizona Diamondbacks | Mobile (AA) | Placed on temporary inactive list |
| Kellin Deglan | C | 23.063 | Texas Rangers | High Desert (A+) | Placed on temporary inactive list |
| Robert Whalen | P | 21.155 | New York Mets | St. Lucie (A+) | DL-7 Injured |
| Ronard Castillo | LF | 23.019 | | | Released by Cardinals |
| Yoel Mecias | P | 21.267 | | | Released by Phillies |
| Dan Langfield | P | 24.165 | Cincinnati Reds | Dayton (A) | DL-7 Injured |
| Francisco Castillo | 2b | 22.031 | Milwaukee Brewers | Wisconsin (A) | DL-7 Injured |
| Jared Breen | IF | 24.055 | Baltimore Orioles | Delmarva (A) | DL-60 Injured |
| Jonah Wesely | P | 20.209 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| London Lindley | of | 22.023 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Mitch Watrous | P | 22.186 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Ryan Atwood | P | 23.328 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Andrew Noviello | c | 18.254 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Placed on temporary inactive list |
| Henry Santana | of | 20.198 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Assigned to DSL Phillies (Rk) |
| Jake Reppert | p | 22.321 | | | Released by Phillies |
| Logan Allen | p | 18.043 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Placed on temporary inactive list |
| Max Watt | p | 20.330 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Placed on temporary inactive list |
| Tyler Spoon | of | 22.280 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Placed on temporary inactive list |
| Brett Bochy | P | 27.313 | San Francisco Giants | Sacramento (AAA) | Designated for Assignment |
| Tyler Brown | ss | 20.168 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (College of Southern Nevada) |
| Tyler Payne | c | 22.253 | Chicago Cubs | Arizona Cubs (Rk) | Signed out of draft (West Virginia State) |
| Andrew Suarez | p | 22.297 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Miami) |
| David Hill | p | 21.039 | Colorado Rockies | Boise (A-) | Signed out of draft (Vanguard) |
| David Olmedo-Barrera | of | 21.013 | Tampa Bay Rays | Princeton (Rk) | Signed out of draft (Cal State Fullerton) |
| Gabe Clark | 1b | 20.273 | Toronto Blue Jays | Bluefield (Rk) | SIgned out of draft (Oregon State) |
| Garrett Cleavinger | p | 21.073 | Baltimore Orioles | Aberdeen (A-) | Signed out of draft (Oregon) |
| Grant Watson | p | 22.003 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (UCLA) |
| Brett Booth | C | 24.266 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
