| CJ Riefenhauser | RP | 25.152 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Preston Guilmet | RP | 27.340 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Ronald Belisario | RP | 32.182 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Designated for Assignment |
| Kirby Yates | RP | 28.098 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Bryan Morris | RP | 28.095 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Jared Burton | RP | 34.029 | | | Released by Rangers |
| Ethan Martin | SP | 26.025 | Philadelphia Phillies | Reading (AA) | Outrighted to minors |
| Iolana Akau | C | 19.305 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Blake Allemand | ss | 23.000 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| Erwin Almonte | 1b | 20.129 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Brandon Beachy | SP | 28.301 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) for rehab |
| Cam Bedrosian | RP | 23.273 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Jose Berrios | P | 21.035 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Charles Brewer | RP | 27.085 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| David Buchanan | SP | 26.051 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Ali Castillo | 2B | 26.012 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Jose Chavez | C | 19.331 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Scott Diamond | SP | 28.336 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Joey Donofrio | P | 26.052 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Juan Duran | LF | 23.303 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Nick Frey | P | 23.306 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Junior Guerra | RP | 30.166 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Hector Guevara | 2B | 23.268 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Alen Hanson | SS | 22.252 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from disabled list |
| Derek Hill | OF | 19.184 | Detroit Tigers | West Michigan (A) | Activated from disabled list |
| DJ Johnson | P | 25.305 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Jake Junis | P | 22.288 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Kyle Keller | p | 22.064 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Zach Lee | P | 23.292 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Activated from disabled list |
| Nelson Leon | P | 20.002 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Jake Marisnick | CF | 24.093 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) for rehab |
| Kevin Medrano | IF | 25.041 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Carlos Moncrief | RF | 26.240 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Alex Muren | OF-P | 23.238 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Aaron Northcraft | P | 25.034 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Mike Olt | 3b | 26.308 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Matt Pagnozzi | C | 32.233 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Daniel Pigott | C-OF | 25.270 | Cincinnati Reds | Arizona Reds (Rk) | Assigned to Arizona Reds (Rk) |
| Argenis Raga | 3B | 20.344 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Colin Rea | P | 25.000 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Esmil Rogers | RP | 29.321 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Randy Rosario | P | 21.044 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Austin Schotts | OF | 21.288 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Louis Silverio | OF | 21.198 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Gregory Soto | p | 20.140 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Ryan Stephens | OF | 22.360 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Ethan Stewart | P | 24.163 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Activated from disabled list |
| Ricardo Valenzuela | C | 24.331 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Yordano Ventura | P | 24.028 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) for rehab |
| Carl Wise | 3b | 21.037 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Dan Jennings | RP | 28.075 | Chicago White Sox | Chicago White Sox (MLB) | Activated from DL |
| Matt Magill | SP | 25.233 | Cincinnati Reds | Daytona (A+) | DL-60 Injured |
| Scott Snodgress | P | 25.284 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Charles Moorman | C | 21.173 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Frederick Tiburcio | P | 24.242 | | | Released by Astros |
| Josciel Veras | SS | 22.206 | Cincinnati Reds | Louisville (AAA) | DL-7 Injured |
| Jose Monegro | P | 25.285 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Dixon Llorens | P | 22.225 | St. Louis Cardinals | Peoria (A) | DL-7 Injured |
| Mike Snyder | 3B | 25.014 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Albert Minnis | P | 23.239 | Houston Astros | Lancaster (A+) | DL-7 Injured |
| Alfredo Gonzalez | C | 22.353 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Chad Wallach | P | 23.240 | Cincinnati Reds | Daytona (A+) | DL-7 Injured |
| Cole Swanson | P | 23.087 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Jimmy Yezzo | IF | 23.125 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Phil Ervin | OF | 22.349 | Cincinnati Reds | Daytona (A+) | DL-7 Injured |
| Sean Dwyer | 1B | 23.209 | | | Released by Rockies |
| Sean Townsley | P | 24.285 | Miami Marlins | Jupiter (A+) | DL-7 Injured |
| Brennan Middleton | IF | 24.223 | | | Released by Nationals |
| Raudy Read | C | 21.245 | Washington Nationals | Hagerstown (A) | Placed on temporary inactive list |
| Stefan Crichton | P | 23.122 | Baltimore Orioles | Delmarva (A) | Placed on temporary inactive list |
| Tim Hill | P | 25.141 | Kansas City Royals | Idaho Falls (Rk) | DL-60 Injured |
| Carlos Cartagena | OF | 21.191 | | | Released by Giants |
| Grant Hockin | P | 19.118 | Cleveland Indians | Arizona Indians (Rk) | DL-7 Injured |
| Gustavo Cabrera | of | 19.160 | San Francisco Giants | Arizona Giants (Rk) | DL-7 Injured |
| Jordan Dunatov | OF | 22.254 | Cleveland Indians | Arizona Indians (Rk) | DL-7 Injured |
| Nicol Parra | OF | 20.338 | | | Released by Giants |
| Ricardo Rodriguez | c | 17.193 | San Diego Padres | San Diego Padres (MLB) | Assigned to DSL Padres (Rk) |
| Sam Lewis | P | 23.266 | Kansas City Royals | Idaho Falls (Rk) | DL-60 Injured |
| Andrew Noviello | c | 18.250 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (Massachusetts HS) |
| Bryce Denton | 3b | 17.334 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Signed out of draft (Tennessee HS) |
| Garrett Whitley | of | 18.110 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed out of draft (New York HS) |
| Kory Groves | p | 22.302 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (Cal State Monterey Bay) |
| Mac Marshall | p | 19.156 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Georgia HS) |
| Matthew Foley | c | 21.077 | Miami Marlins | Gulf Coast Marlins (Rk) | Signed out of draft (Rhode Island College) |
| Nolan Watson | p | 18.157 | Kansas City Royals | Burlington (Rk) | Signed out of draft (Indiana HS) |
| Gilmael Troya | p | 18.088 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees (Rk) |
| Jose Santos | p | 23.115 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to AZL Dodgers (Rk) |
| Matt LeVert | p | 22.253 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (Cal State San Bernardino) |
| AJ Simcox | ss | 21.009 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Signed out of draft (Tennessee HS) |
| Andrew Benintendi | of | 20.360 | Boston Red Sox | Lowell (A-) | Signed out of draft (Arkansas) |
| Austin Rei | c | 21.247 | Boston Red Sox | Lowell (A-) | Signed out of draft (Washington) |
| Bobby Poyner | p | 22.212 | Boston Red Sox | Lowell (A-) | Signed out of draft (Florida) |
| Charles Galiano | c | 21.039 | Milwaukee Brewers | Helena (Rk) | Signed out of draft (Fordham) |
| Mark Weist | 3b | 22.323 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Michigan State) |
| Max Cordy | p | 22.022 | Minnesota Twins | Gulf Coast Twins (Rk) | Signed out of draft (UC Davis) |
| Steven Klimek | p | 21.088 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (St. Bonaventure) |
| William Shepley | p | 22.045 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (UNC Wilmington) |
| Xavier Borde | p | 22.080 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (Arizona) |
| Jeremy Hadley | OF | 20.222 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Assignment unknown |
| Mario Adames | P | 23.033 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Assignment unknown |
| Christian Cecilio | p | 22.149 | San Diego Padres | San Diego Padres (MLB) | Assignment unknown |
| Luis Lara | C | 20.148 | Kansas City Royals | Kansas City Royals (MLB) | Assignment unknown |
| Brett Booth | C | 24.262 | Houston Astros | Corpus Christi (AA) | Placed on temporary inactive list |
| Tom Eshelman | p | 21.011 | Houston Astros | Gulf Coast Astros (Rk) | Signed out of draft (Cal State Fullerton) |
