| Colby Rasmus | cf | 28.309 | Houston Astros | Houston Astros (MLB) | Placed on bereavement list |
| Domingo Santana | RF-LF | 22.315 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Kevin Gregg | RP | 36.361 | | | Released by Mariners |
| Wil Myers | rf | 24.188 | San Diego Padres | San Diego Padres (MLB) | DL-15 Bone spurs, left wrist |
| Cory Mazzoni | P | 25.240 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| James Jones | RF | 26.265 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Aaron Sanchez | P | 22.350 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Right lat strain |
| Scott Copeland | P | 27.184 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Robbie Ross | RP | 25.357 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Jeff Bianchi | 2b-3b | 28.254 | Boston Red Sox | Boston Red Sox (MLB) | Designated for Assignment |
| Akeel Morris | P | 22.214 | New York Mets | New York Mets (MLB) | Recalled from St. Lucie (A+) |
| Dillon Gee | SP | 29.049 | New York Mets | New York Mets (MLB) | Designated for Assignment |
| Grady Sizemore | CF | 32.318 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Signed to Minor League Contract |
| Luis Jimenez | 3B | 27.150 | | | LG |
| Kirk Nieuwenhuis | lf | 27.314 | New York Mets | New York Mets (MLB) | Outrighted to minors |
| Martin Viramontes | P | 25.339 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Trea Turner | SS | 21.351 | Washington Nationals | Washington Nationals (MLB) | Officially traded to Nationals |
| Wei-Chung Wang | P | 23.052 | Milwaukee Brewers | Brevard County (A+) | Designated for Assignment |
| Ender Inciarte | RF | 24.230 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-15 Right hamstring strain |
| Matt Dominguez | 3b | 25.292 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Claimed off waivers from Astros by Brewers |
| Chris Parmelee | 1B | 27.113 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Wei-Yin Chen | SP | 29.330 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Jonathan Schoop | 2B | 23.254 | Baltimore Orioles | Baltimore Orioles (MLB) | Transferred to 60-day DL |
| Keon Barnum | 1B | 22.151 | Chicago White Sox | Winston-Salem (A+) | Activated from disabled list |
| Joel Bender | P | 23.318 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Brennan Boesch | LF | 30.065 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Chris Bostick | SS-2B | 22.084 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Rashad Brown | OF | 21.181 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Miguel Celestino | P | 25.249 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Paul Clemens | SP | 27.123 | Philadelphia Phillies | Clearwater (A+) | Activated from disabled list |
| Caleb Cotham | P | 27.223 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Nicky Delmonico | 1B-2B | 22.339 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Ronald Dominguez | P | 21.154 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Kelly Dugan | RF | 24.271 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Cutter Dykstra | 2B-LF | 25.352 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Luke Eubank | P | 21.112 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Willy Garcia | CF-RF | 22.285 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Francisco Gonzalez | P | 20.268 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Rick Hague | SS | 26.271 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Chase Harris | OF | 23.324 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Donnie Hart | P | 24.283 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Brett Jackson | cf | 26.318 | San Francisco Giants | Sacramento (AAA) | Activated from disabled list |
| Kevin Keyes | RF | 26.093 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Rainy Lara | P | 24.094 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Mark Leiter | P | 24.095 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Adam Loewen | 1B-RF | 31.068 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Jose Lozada | 3B-SS | 29.169 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Justin Marks | P | 27.156 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Yoel Mecias | P | 21.248 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Kirk Nieuwenhuis | LF | 27.314 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| James Pazos | P | 24.042 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Jake Peavy | SP | 34.016 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) for rehab |
| Ricardo Pinto | P | 21.147 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Carlos Ramirez | OF | 24.053 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Calvin Rayburn | P | 23.128 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Jared Reaves | IF | 24.331 | Detroit Tigers | Erie (AA) | Activated from disabled list |
| Zac Reininger | P | 22.139 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Jo-Jo Reyes | P | 30.208 | Los Angeles Angels | Salt Lake (AAA) | Signed to Minor League Contract |
| Luis Reyes | P | 20.263 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Joely Rodriguez | P | 23.215 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Mel Rojas | CF | 25.023 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Adrian Sanchez | 2B | 24.304 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Joe Sclafani | IF | 25.055 | Houston Astros | Fresno (AAA) | Reinstated to active roster |
| Slade Smith | P | 24.263 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Carlos Tocci | | 19.298 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Devon Travis | 2B | 24.115 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) for rehab |
| Trea Turner | SS | 21.351 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Ricardo Valencia | c | 22.154 | Texas Rangers | Hickory (A) | Activated from disabled list |
| Kyle Wren | OF | 24.054 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Jose Yepez | C | 33.362 | Atlanta Braves | Gwinnett (AAA) | Activated from disabled list |
| Elliot Johnson | 2b | 31.099 | Los Angeles Dodgers | Oklahoma City (AAA) | DL-7 Injured |
| Omar Quintanilla | ss | 33.235 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
| Wil Nieves | c | 37.264 | | | Released by Braves |
| Boone Whiting | P | 25.300 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
| Daniel Mayora | 3B | 29.324 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Robert Morey | P | 26.201 | Miami Marlins | New Orleans (AAA) | DL-7 Injured |
| Skyler Stromsmoe | SS-LF | 31.078 | San Francisco Giants | Sacramento (AAA) | DL-7 Injured |
| Adam Ehrlich | C | 22.185 | St. Louis Cardinals | Peoria (A) | DL-7 Injured |
| Kevin Shackelford | P | 26.070 | Cincinnati Reds | Pensacola (AA) | DL-7 Injured |
| Boomer Collins | IF | 26.003 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Hector Hernandez | P | 24.116 | Arizona Diamondbacks | Kane County (A) | DL-7 Injured |
| Ian Gardeck | P | 24.207 | San Francisco Giants | San Jose (A+) | DL-7 Injured |
| JP Sportman | IF | 23.142 | Oakland Athletics | Stockton (A+) | DL-7 Injured |
| Michael Kraft | P | 23.287 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Sam Holland | P | 21.116 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Andrew Case | P | 22.161 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Brad Markey | P | 23.105 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Jefry Rodriguez | p | 21.325 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Jomar Reyes | 3B | 18.116 | Baltimore Orioles | Delmarva (A) | DL-7 Sprained right thumb |
| Jose Castillo | P | 19.158 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Nick Vilter | 2B-3B | 21.253 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Reed Reilly | P | 23.163 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Robbie Dickey | P | 21.071 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Tanner Banks | P | 23.236 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| E.J. Encinosa | P | 23.316 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Ronald Belisario | RP | 32.167 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Contract purchased from minors |
| Raudel Lazo | P | 26.065 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Carlos Peguero | rf | 28.114 | Boston Red Sox | Pawtucket (AAA) | Signed to Minor League Contract |
| Frankie Reed | P | 27.125 | | | Released by Marlins |
| Jerry Keel | p | 21.263 | San Diego Padres | Tri-City (A-) | Signed out of draft (Cal State Northridge) |
| Anthony Swarzak | RP | 29.279 | | | Signed with Doosan Bears (Korea) |
