| Everth Cabrera | ss | 28.201 | Baltimore Orioles | Baltimore Orioles (MLB) | Designated for Assignment |
| Cesar Cabral | P | 26.115 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Matt Wieters | C | 29.016 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Rey Navarro | 2B-3B | 25.166 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Rajai Davis | LF | 34.230 | Detroit Tigers | Detroit Tigers (MLB) | Reinstated from Paternity Leave |
| Dustin McGowan | RP | 33.074 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Tommy Pham | CF | 27.090 | St. Louis Cardinals | Memphis (AAA) | Activated from DL and assigned to Memphis (AAA) |
| Matt Adams | 1b | 26.279 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Transferred to 60-day DL |
| Jeff Mathis | C | 32.067 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Jhonatan Solano | C | 29.298 | Miami Marlins | Miami Marlins (MLB) | Designated for Assignment |
| Joey Terdoslavich | lf | 26.270 | Atlanta Braves | Atlanta Braves (MLB) | Activated from DL |
| Eric Young | lf | 30.012 | Atlanta Braves | Atlanta Braves (MLB) | Designated for Assignment |
| Danny Muno | SS | 26.117 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Daniel Murphy | 2b | 30.066 | New York Mets | New York Mets (MLB) | DL-15 Strained left quad |
| Pat Venditte | P | 29.341 | Oakland Athletics | Oakland Athletics (MLB) | Contract purchased from minors |
| Coco Crisp | cf | 35.218 | Oakland Athletics | Oakland Athletics (MLB) | Transferred to 60-day DL |
| Jean Machi | RP | 32.125 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Strained left groin |
| Casey McGehee | DH | 32.237 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Scott Schebler | RF | 24.243 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Jon Moscot | P | 23.296 | Cincinnati Reds | Cincinnati Reds (MLB) | Contract purchased from minors |
| Pedro Villarreal | RP | 27.180 | Cincinnati Reds | Cincinnati Reds (MLB) | Recalled from Louisville (AAA) |
| Jason Marquis | SP | 36.289 | Cincinnati Reds | Cincinnati Reds (MLB) | Designated for Assignment |
| Joe Ross | P | 22.016 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from minors |
| A.J. Cole | P | 23.153 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Craig Stammen | RP | 31.089 | Washington Nationals | Washington Nationals (MLB) | Transferred to 60-day DL |
| Jake Lamb | 3B | 24.240 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Jordan Pacheco | c-1B | 29.127 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Designated for Assignment |
| Martin Agosta | P | 24.060 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Carlos Arroyo | OF | 21.343 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Andrew Bellatti | P | 23.306 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Sean Buckley | 3B | 25.276 | Cincinnati Reds | Pensacola (AA) | Activated from disabled list |
| Lindsey Caughel | P | 24.297 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Tommy Field | 2b | 28.104 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Matt Fields | 1B | 29.333 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| Caleb Gindl | rf-LF | 26.279 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Anthony Hewitt | RF | 26.040 | Baltimore Orioles | Frederick (A+) | Activated from disabled list |
| Edgar Ibarra | P | 26.006 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Jon Kemmer | LF | 24.201 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
| Angelo Leclerc | P | 23.241 | Texas Rangers | High Desert (A+) | Assigned to High Desert (A+) |
| Devin Lohman | SS-2B | 26.053 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Hector Lorenzana | IF | 23.251 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Brett Martin | P | 20.039 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Harold Martinez | 3B | 25.034 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| L.J. Mazzilli | IF | 24.273 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Martin Medina | 1B-C | 25.074 | Toronto Blue Jays | Dunedin (A+) | Traded from White Sox to Blue Jays for cash |
| Luis Miranda | P | 20.274 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Jose Monegro | P | 25.260 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Miles Nordgren | P | 22.359 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Mike O'Neill | LF | 27.115 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Luis Perez | P | 30.137 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Ryan Plourde | C-OF | 23.101 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Dalton Pompey | CF | 22.177 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Michael Ratterree | SS | 24.117 | Milwaukee Brewers | Brevard County (A+) | Assigned to Brevard County (A+) |
| Nick Rodesky | P | 24.071 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Yeixon Ruiz | | 24.079 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Jerry Sands | LF-1B | 27.252 | Cleveland Indians | Columbus (AAA) | Outrighted to minors |
| Scott Schebler | RF | 24.243 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Ross Seaton | P | 25.261 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Matthew Spann | P | 24.109 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Bubba Starling | OF | 22.307 | Kansas City Royals | Northwest Arkansas (AA) | Activated from disabled list |
| Cole Sturgeon | OF-P | 23.263 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Richie Tate | P | 23.056 | Atlanta Braves | Carolina (A+) | Assigned to Carolina (A+) |
| Jose Veras | RP | 34.229 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| David Washington | 1B | 24.198 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| J.T. Watkins | C | 25.280 | Boston Red Sox | Salem (A+) | Reinstated to active roster |
| Gianfranco Wawoe | 2B | 20.316 | Seattle Mariners | Jackson (AA) | Assigned to Jackson (AA) |
| Austen Williams | P | 22.169 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Roman Mendez | P | 24.316 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Tyler Holt | CF | 26.088 | Cleveland Indians | Columbus (AAA) | DL-7 Injured |
| Jhonatan Ramos | P | 25.303 | Baltimore Orioles | Bowie (AA) | DL-7 Injured |
| Mitch Lively | P | 29.272 | Washington Nationals | Syracuse (AAA) | Placed on temporary inactive list |
| Michael Burgess | RF | 26.229 | | | Released by Orioles |
| Tim Roberson | C | 25.322 | Boston Red Sox | Portland (AA) | DL-7 Injured |
| Tyler Mizenko | P | 25.058 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Cole Lankford | C | 22.276 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Collin Radack | OF | 23.068 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Elio Castillo | 1B | 21.097 | Texas Rangers | Texas Rangers (MLB) | Assigned to extended spring training |
| Travis Radke | P | 22.092 | San Diego Padres | San Diego Padres (MLB) | Assigned to extended spring training |
| Ty McFarland | 2B | 23.237 | New York Yankees | New York Yankees (MLB) | Assigned to extended spring training |
| Will Morris | P | 22.035 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Assigned to extended spring training |
| Emilio Ogando | P | 21.297 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Jason Zgardowski | P | 21.252 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Assigned to extended spring training |
| Justin Atkinson | 3B | 21.317 | Toronto Blue Jays | Lansing (A) | DL-7 Injured |
| Luiz Gohara | P | 18.310 | Seattle Mariners | Seattle Mariners (MLB) | Assigned to extended spring training |
| Luke Curtis | P | 23.158 | Milwaukee Brewers | Wisconsin (A) | DL-7 Injured |
| Tyler Moore | C-IF | 21.302 | New York Mets | Savannah (A) | DL-7 Injured |
| Wigberto Nevarez | C | 23.263 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Dane McFarland | CF | 20.225 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assigned to extended spring training |
| Luis Ortiz | P | 19.258 | Texas Rangers | Texas Rangers (MLB) | Assigned to extended spring training |
| Trevor Bayless | P | 23.244 | Oakland Athletics | Stockton (A+) | DL-7 Injured |
