| Gordon Beckham | 2b | 27.340 | Los Angeles Angels | Los Angeles Angels (MLB) | Traded from White Sox to Angels for PTBNL (Yency Almonte) |
| Yolmer Sanchez | 2B | 22.054 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Craig Gentry | lf-cf | 30.267 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL |
| Daniel Corcino | P | 23.361 | Cincinnati Reds | Cincinnati Reds (MLB) | Recalled from Pensacola (AA) |
| Brandon Belt | 1b | 26.124 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Concussion |
| Dan Jennings | RP | 27.127 | Miami Marlins | Miami Marlins (MLB) | DL-15 Concussion (Transferred) |
| Tim Anderson | SS | 21.060 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Victor Araujo | | 21.286 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Nestor Bautista | P | 22.101 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Tyler Beede | P | 21.091 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Sean Bierman | P | 25.306 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Ray Black | P | 24.057 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Brett Bruening | P | 25.235 | Chicago White Sox | Arizona White Sox (Rk) | Activated from disabled list |
| Colton Cain | P | 23.198 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
| Miguel Castro | P | 19.241 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Kramer Champlin | P | 24.167 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Mike Connolly | IF | 22.296 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Jonathan Cornelius | P | 26.083 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Kevin Cornelius | SS | 21.359 | New York Yankees | Gulf Coast Yankees (Rk) | Activated from disabled list |
| Keith Couch | P | 24.290 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| William Cuevas | P | 23.312 | Boston Red Sox | Salem (A+) | Activated from disabled list |
| Ryan Dennick | P | 27.224 | Cincinnati Reds | Louisville (AAA) | Reinstated to active roster |
| Osvaldo Duarte | SS | 18.217 | Houston Astros | Gulf Coast Astros (Rk) | Activated from disabled list |
| Gene Escat | P | 24.353 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Ronnierd Garcia | 3B-1B | 21.233 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Gonzalez Germen | RP | 26.334 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Sean Godfrey | OF | 22.233 | Atlanta Braves | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Mitch Haniger | OF | 23.242 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Alex Hassan | LF | 26.143 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| David Hess | P | 21.043 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Ryan Jackson | 2B-SS | 26.104 | San Diego Padres | Arizona Padres (Rk) | Assigned to AZL Padres (Rk) for rehab |
| Nick Jones | P | 22.342 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Michael Joseph | P | 23.344 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| George Kontos | RP | 29.071 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) |
| Alexander Labrador | C | 19.299 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Cody Livesay | OF | 21.047 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Joseph Maher | P | 22.017 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Jason McCracken | P | 22.353 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Daniel McCutchen | P | 31.330 | Chicago White Sox | Charlotte (AAA) | Activated from disabled list |
| Shawn McGill | C | 30.175 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Alex McKeon | C-1B | 21.094 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Yohander Mendez | P | 19.217 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Sam Moll | P | 22.232 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Mitch Morales | SS | 21.172 | San Diego Padres | Eugene (A-) | Assigned to Eugene (A-) |
| Jan Novak | P | 20.215 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Chace Numata | C | 22.008 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Danny Otero | RP | 29.184 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Joey Paciorek | C | 25.336 | Milwaukee Brewers | Huntsville (AA) | Reinstated to active roster |
| Willy Paredes | | 25.201 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Blake Parker | RP | 29.064 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Brooks Pounders | P | 23.330 | Kansas City Royals | Wilmington (A+) | Activated from disabled list |
| Heri Quevedo | P | 24.076 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Dylan Rheault | P | 22.154 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Dae-Eun Rhee | P | 25.152 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Steve Sabatino | P | 24.167 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Luis Santos | P | 23.192 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Casey Shane | p | 18.365 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Ryan Sherriff | P | 24.089 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Eric Sim | C | 25.231 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Aaron Slegers | P | 21.352 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Jake Smith | P | 24.081 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Sammy Solis | P | 26.012 | Washington Nationals | Gulf Coast Nationals (Rk) | Activated from disabled list |
| Rowdy Tellez | 1B | 19.159 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Richard Urena | SS | 18.178 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Daniel Wagner | 2B | 26.041 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Jemile Weeks | 2b | 27.208 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Bartolo Colon | RP | 39.090 | New York Mets | New York Mets (MLB) | Reinstated from Bereavement list |
| Corey Knebel | P | 22.270 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Frank De los Santos | P | 26.279 | Chicago White Sox | Charlotte (AAA) | DL-7 Injured |
| Hector Ambriz | RP | 30.085 | | | Released by Padres |
| Jose Valdez | P | 31.212 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Kevin Mattison | CF | 28.336 | | | Released by Brewers |
| Tim Berry | P | 23.157 | Baltimore Orioles | Bowie (AA) | DL-7 Injured |
| Jake Thompson | P | 25.014 | Tampa Bay Rays | Durham (AAA) | Placed on temporary inactive list |
| Jeff Ibarra | P | 27.004 | San Diego Padres | San Antonio (AA) | DL-7 Injured |
| Jose Toussen | SS-2B | 24.282 | New York Yankees | Trenton (AA) | DL-7 Injured |
| Tyson Blaser | C-1B | 26.258 | New York Yankees | Trenton (AA) | DL-7 Injured |
| Zak Hermans | P | 23.062 | Chicago Cubs | Kane County (A) | DL-7 Injured |
| Chipper Smith | P | 24.212 | Miami Marlins | Jacksonville (AA) | DL-7 Injured |
| Chris Devenski | P | 23.282 | Houston Astros | Corpus Christi (AA) | Placed on temporary inactive list |
| Micah Gibbs | C | 26.026 | Kansas City Royals | Northwest Arkansas (AA) | DL-7 Injured |
| Mike Augliera | P | 24.075 | Boston Red Sox | Portland (AA) | Placed on temporary inactive list |
| Austin Wilson | OF | 22.197 | Seattle Mariners | Clinton (A) | DL-7 Injured |
| Josue Montanez | P | 22.220 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Andrew Dennis | C | 21.145 | Pittsburgh Pirates | Bristol (Rk) | DL-60 Injured |
| Ramon Laureano | OF | 20.038 | Houston Astros | Greeneville (Rk) | DL-60 Injured |
| Javier Hernandez | C | 18.032 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to GCL Blue Jays (Rk) |
| Jose Fernandez | OF | 20.267 | Cincinnati Reds | Cincinnati Reds (MLB) | Assignment unknown |
| Freddy Galvis | 3b | 24.281 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Freddy Galvis | 3b | 24.281 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Travis Brewster | OF | 22.214 | Miami Marlins | Gulf Coast Marlins (Rk) | Signed as undrafted free agent (Grayson CC) |
| Jason Zgardowski | P | 20.329 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Signed as undrafted free agent (Angelo State) |
| Justin Henry | CF-3B | 29.114 | Boston Red Sox | Pawtucket (AAA) | Placed on temporary inactive list |
| Charles Leesman | SP | 27.165 | - | | Cleared Waivers and Became a Free Agent |
| Dan Jennings | RP | 27.127 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) for rehab |
| Ryan Lamarre | CF | 25.274 | Cincinnati Reds | Cincinnati Reds (MLB) | Signed to Minor League Contract |
