| Will Middlebrooks | 3b | 25.326 | Boston Red Sox | Boston Red Sox (MLB) | Activated from DL |
| Ezequiel Carrera | rf | 27.051 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Patrick McCoy | P | 25.363 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from minor league rehab assignment |
| Patrick McCoy | P | 25.363 | Detroit Tigers | Detroit Tigers (MLB) | Activated from DL |
| Felix Doubront | SP | 26.283 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Strained right calf |
| Cesar Jimenez | RP | 29.262 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Cliff Lee | SP | 35.336 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-15 Left flexor pronator strain |
| Sven Schueller | P | 18.197 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to AZL Dodgers (Rk) |
| Engel Beltre | RF | 24.273 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) for rehab |
| Mike Foltynewicz | P | 22.299 | Houston Astros | Houston Astros (MLB) | Contract purchased from minors |
| Mookie Betts | OF | 21.298 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Mike Carp | 1b | 28.032 | Boston Red Sox | Boston Red Sox (MLB) | Designated for Assignment |
| Tom Layne | RP | 29.272 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Shane Victorino | rf | 33.244 | Boston Red Sox | Boston Red Sox (MLB) | DL-15 Back |
| Alex Wilson | RP | 27.271 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Michael Roth | RP | 24.167 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Arkansas (AA) |
| Tyler Skaggs | SP | 23.019 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Strained left forearm |
| Jim Johnson | RP | 31.035 | - | | Released by Athletics |
| Ryan Feierabend | P | 28.344 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| Phil Klein | P | 25.093 | Texas Rangers | Texas Rangers (MLB) | Contract purchased from minors |
| Jordan Schafer | cf-RF | 27.331 | Atlanta Braves | Atlanta Braves (MLB) | Designated for Assignment |
| Shane Robinson | cf-RF | 29.275 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Tyler Colvin | lf | 28.330 | San Francisco Giants | San Francisco Giants (MLB) | Designated for Assignment |
| Matt Duffy | IF | 23.198 | San Francisco Giants | San Francisco Giants (MLB) | Contract purchased from minors |
| Jarrett Parker | RF | 25.212 | San Francisco Giants | San Francisco Giants (MLB) | Contract purchased from minors |
| Dan Uggla | 2b | 34.143 | San Francisco Giants | San Francisco Giants (MLB) | Designated for Assignment |
| Jayson Nix | 3b | 31.340 | - | | Released by Rays |
| Jay Bruce | RF | 27.120 | Cincinnati Reds | Cincinnati Reds (MLB) | Reinstated from Bereavement List |
| Ryan Webb | RP | 28.177 | Baltimore Orioles | Baltimore Orioles (MLB) | Designated for Assignment |
| Tyler Holt | CF | 25.144 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Zach McAllister | SP | 26.237 | Cleveland Indians | Cleveland Indians (MLB) | Designated for Assignment |
| Evan Scribner | RP | 29.013 | Oakland Athletics | Oakland Athletics (MLB) | Designated for Assignment |
| Henderson Alvarez | SP | 24.105 | Miami Marlins | Miami Marlins (MLB) | DL-15 Right shoulder inflammation |
| Anthony Ranaudo | P | 24.326 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Chris Valaika | 2b | 28.352 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| Tony Abreu | 2B | 29.261 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) |
| Octavio Acosta | P | 23.363 | New York Mets | Savannah (A) | Assigned to Savannah (A) |
| Zoilo Almonte | lf | 25.052 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Dario Alvarez | P | 25.196 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Andrew Aplin | OF | 23.133 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Taylor Ard | IF | 24.182 | Arizona Diamondbacks | South Bend (A) | Assigned to South Bend (A) |
| Luis Arrizurieta | C | 22.357 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Collin Balester | P | 28.056 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Tyler Barnette | P | 22.065 | Chicago White Sox | Kannapolis (A) | Activated from disabled list |
| Aaron Barrett | P | 26.212 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Cody Bellinger | 1B | 19.019 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Elliott Blair | LF-CF | 26.180 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Zach Borenstein | LF | 24.009 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Matt Branham | P | 26.308 | San Diego Padres | San Antonio (AA) | Activated from disabled list |
| Bryce Brentz | RF | 25.214 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Ben Brewster | P | 22.261 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Jake Brigham | P | 26.173 | Pittsburgh Pirates | Jamestown (A-) | Assigned to Jamestown (A-) |
| Tyler Brunnemann | P | 22.358 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Connor Buchmann | P | 21.021 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Jake Burnette | P | 21.356 | Pittsburgh Pirates | Bristol (Rk) | Assigned to Bristol (Rk) |
| Billy Burns | CF | 24.336 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Will Callaway | IF | 24.230 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Mitch Canham | C | 29.310 | Washington Nationals | Harrisburg (AA) | Activated from disabled list |
| Victor Caratini | C-IF | 20.349 | Chicago Cubs | Kane County (A) | Assigned to Kane County (A) |
| Yusuf Carter | c | 29.176 | Toronto Blue Jays | New Hampshire (AA) | Activated from disabled list |
| Miguel Castro | P | 19.220 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Juan Centeno | C | 24.258 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Taylor Cole | P | 24.346 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Maikis De La Cruz | CF-RF | 23.329 | New York Mets | St. Lucie (A+) | Activated from disabled list |
| Carlos Diaz | P | 20.256 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Chris Diaz | IF | 23.265 | Pittsburgh Pirates | West Virginia (A) | Activated from disabled list |
| Brandon Drury | 3B | 21.345 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Ryan Etsell | P | 22.227 | Los Angeles Angels | Arizona Angels (Rk) | Activated from disabled list |
| Justin Fitzgerald | P | 28.151 | Arizona Diamondbacks | Mobile (AA) | Activated from disabled list |
| Dustin Fowler | CF | 19.215 | New York Yankees | Charleston (sc) (A) | Activated from disabled list |
| Chris Freudenberg | P | 21.043 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Jeremy Gabryszwski | P | 21.138 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Audry German | P | 21.350 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Derrik Gibson | SS | 24.239 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Cristian Gomez | | 18.203 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Miguel Gonzalez | P | 27.312 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Zack Granite | OF | 21.318 | Minnesota Twins | Gulf Coast Twins (Rk) | Activated from disabled list |
| Kendall Graveman | P | 23.223 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Jeremy Hefner | SP | 28.143 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Jeremy Hermida | RF | 30.184 | Milwaukee Brewers | Nashville (AAA) | Activated from disabled list |
| Jefri Hernandez | P | 23.096 | Colorado Rockies | Asheville (A) | Activated from disabled list |
| Matt Hoffman | P | 25.256 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Tyler Horan | OF | 23.242 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| James Jones | RF | 25.311 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Tyler Kane | P | 21.343 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Branden Kline | P | 22.307 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Ian Krol | RP | 23.084 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Jake Lamb | 3B | 23.296 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Domingo Leyba | 2B | 18.325 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Corey Littrell | P | 22.133 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Johnnie Lowe | P | 29.133 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Ed Lucas | 3b | 32.072 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Domenick Mancini | P | 20.307 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Shaun Marcum | SP | 32.230 | Cleveland Indians | Arizona Indians (Rk) | Activated from disabled list |
| Carlos Martinez | RP | 22.315 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Kenny Mathews | P | 20.360 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Mike McCarthy | P | 26.257 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| John Mcleod | P | 22.059 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) for rehab |
| Steve McQuail | OF | 25.052 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Edwin Medina | OF | 21.171 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Sam Mende | 3B | 24.204 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Blake Miller | IF | 24.098 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Colin Moran | 3B-1B | 21.304 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Julio Morillo | C | 21.217 | Cincinnati Reds | Arizona Reds (Rk) | Assigned to Arizona Reds (Rk) |
| Josh Mueller | P | 25.195 | Colorado Rockies | Tulsa (AA) | Assigned to Tulsa (AA) |
| Aaron Munoz | C | 25.220 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Reymond Nunez | 1B | 23.310 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Peter O'Brien | C | 24.017 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Randy Ortiz | OF | 21.047 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Roberto Osuna | P | 19.175 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Henry Owens | P | 22.011 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Tyler Palmer | IF-OF | 22.316 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Wes Parsons | P | 21.329 | Atlanta Braves | Lynchburg (A+) | Activated from disabled list |
| Curtis Partch | RP | 27.169 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Joel Payamps | P | 20.116 | Colorado Rockies | Tri-City (A-) | Assigned to Tri-City (A-) |
| David Putman | P | 24.154 | Chicago White Sox | Kannapolis (A) | Activated from disabled list |
| Jimmy Reyes | P | 25.147 | Texas Rangers | Round Rock (AAA) | Activated from disabled list |
| Franderlyn Romero | P | 21.161 | Cincinnati Reds | Arizona Reds (Rk) | Activated from disabled list |
| Stefen Romero | 2B | 25.288 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Angel Rosa | SS | 21.316 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Chasen Shreve | P | 24.020 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Aaron Slegers | P | 21.331 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Elliot Soto | SS | 24.345 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Michael Soto | 1B-3B | 22.258 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Drew Stankiewicz | 2B | 21.044 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Ashur Tolliver | P | 26.190 | Baltimore Orioles | Bowie (AA) | Activated from disabled list |
| Wilfredo Tovar | SS | 22.356 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Nick Urbanus | SS-2B | 22.125 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Nick Vander Tuig | P | 22.236 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Austin Wates | CF-LF | 25.333 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Zelous Wheeler | 3B | 27.197 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Leonel Zazueta | p | 19.308 | Minnesota Twins | Gulf Coast Twins (Rk) | Activated from disabled list |
| Brett Tomko | P | 41.116 | Colorado Rockies | Colorado Springs (AAA) | DL-7 Injured |
| Dan Runzler | RP | 29.124 | | | Released by Giants |
| Drew Verhagen | P | 23.283 | Detroit Tigers | Toledo (AAA) | DL-7 Injured |
| Duane Below | RP | 28.259 | Detroit Tigers | Toledo (AAA) | DL-7 Injured |
| Rich Hill | RP | 34.143 | New York Yankees | Scranton/Wilkes-Barre (AAA) | DL-7 Injured |
| Trayvon Robinson | CF | 26.335 | Los Angeles Dodgers | Albuquerque (AAA) | DL-7 Injured |
| Jeff Antigua | P | 24.039 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Jose Yepez | C | 33.043 | Atlanta Braves | Gwinnett (AAA) | DL-7 Injured |
| Nick McCully | P | 25.330 | | | Released by White Sox |
| Cody Winiarski | P | 24.339 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Jon Keller | P | 21.358 | Baltimore Orioles | Frederick (A+) | DL-7 Injured |
| Luis Chirinos | P | 24.101 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Tripp Davis | P | 23.170 | Kansas City Royals | Lexington (A) | DL-7 Injured |
| Wagner Mateo | CF-1B | 21.124 | | | Released by Diamondbacks |
| Gerald Chin | 2B | 21.064 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Hunter Harvey | P | 19.235 | Baltimore Orioles | Delmarva (A) | DL-7 Injured |
| Yean Carlos Gil | P | 23.293 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Stefen Henderson | OF-P | 22.203 | Los Angeles Dodgers | Arizona Dodgers (Rk) | DL-60 Injured |
| Joe Saunders | SP | 33.046 | Baltimore Orioles | Baltimore Orioles (MLB) | Signed to minor league contract |
| Justin Kamplain | P | 21.169 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (A) |
| Jeremy Farrell | 3B | 27.263 | Chicago White Sox | Birmingham (AA) | Reinstated from suspension |
| Michael Earley | LF | 26.139 | Chicago White Sox | Birmingham (AA) | Reinstated from suspension |
| Kevin Vance | P | 24.024 | Chicago White Sox | Birmingham (AA) | Reinstated from suspension |
| Matt Ramsey | P | 24.311 | Miami Marlins | Jacksonville (AA) | Reinstated from suspension |
| Wilfredo Gimenez | C | 23.226 | Miami Marlins | Jacksonville (AA) | Reinstated from suspension |
| Dillon Ortman | P | 22.049 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Lucas Long | P | 21.298 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Tyler Wampler | IF | 22.335 | Los Angeles Angels | Ogden (Rk) | Assigned to Ogden (Rk) |
| James Farris | P | 22.119 | Chicago Cubs | Boise (A-) | Signed out of draft (Arizona) |
| Tyler Beede | P | 21.070 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Vanderbilt) |
| Mark Williams | P | 24.354 | Milwaukee Brewers | Brevard County (A+) | Placed on restricted list |
| Lars Davis | C | 28.267 | Philadelphia Phillies | Lehigh Valley (AAA) | Placed on temporary inactive list |
| Randol Rojas | P | 23.307 | | | Released by Rangers |
| Daniel Lewis | P | 23.128 | Chicago Cubs | Boise (A-) | Signed as undrafted free agent (Pensacola State CC) |
| Alvaro Rondon | SS | 23.329 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to AZL Diamondbacks (Rk) |
